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  1. Article: The Small Fibrous Prostate.

    Fowler, A L

    Atlanta journal-record of medicine

    2022  Volume 62, Issue 2, Page(s) 67–70

    Language English
    Publishing date 2022-08-26
    Publishing country United States
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Surgical Kidney.

    Fowler, A L

    Atlanta journal-record of medicine

    2022  Volume 60, Issue 8, Page(s) 335–343

    Language English
    Publishing date 2022-08-26
    Publishing country United States
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Spinal Anesthesia in Genito-Urinary Surgery.

    Fowler, A L

    Atlanta journal-record of medicine

    2022  Volume 61, Issue 9, Page(s) 391–395

    Language English
    Publishing date 2022-08-26
    Publishing country United States
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Genito-Urinary Clinic-Atlanta Medical College, 11 A. M. Thursday.

    Fowler, A L / Weaver, J Calvin / Armstrong, T B

    Atlanta journal-record of medicine

    2022  Volume 60, Issue 9, Page(s) 410–413

    Language English
    Publishing date 2022-08-26
    Publishing country United States
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: 98 Growth and mineral content of tall fescue grown in manure extracts from horses fed varying trace mineral sources and levels

    Fowler, A.L / Brümmer-Holder, M

    Journal of equine veterinary science. 2021 May, v. 100

    2021  

    Abstract: Horse manure spread on pasture can provide nutrients and minerals to plants, but the effect of horse diet on fecal mineral availability to plants is unknown. This study's objective was to determine if the amount and source of trace minerals (TM) fed to ... ...

    Abstract Horse manure spread on pasture can provide nutrients and minerals to plants, but the effect of horse diet on fecal mineral availability to plants is unknown. This study's objective was to determine if the amount and source of trace minerals (TM) fed to horses would affect the growth and mineral content of plants grown hydroponically in manure extracts. Nine horses were used in a replicated 3 × 3 Latin square design for the study's feeding portion. Horses had ad libitum access to forage and were fed a protein pellet containing one of 3 dietary treatments: a low TM treatment with no added TM (CON) or industry relevant TM level treatments with TM added as either organic TM (ORG) or inorganic TM (ING). Added TM were Co, Cu, Mn, Se, and Zn at equivalent amounts for ORG and ING. There were 3 21-d feeding periods, including a 5-d washout; each horse received each treatment. Feces were collected on d 21 of each period. Manure extracts were made from each horse by mixing wet feces with distilled water (30 g DM/L), incubating for 20 h, and straining. Extracts were combined by treatment and TM concentrations reflected dietary levels, with ING and ORG being similar and greater than CON. Manure extracts, distilled water/negative control (WAT) and Steinman's nutrient solution/positive control (NUT) were applied as liquid treatments. Tall fescue seeds were germinated in a growth chamber, and seedlings transferred to rockwool in pans (40 seedlings/pan) on d 9. Pans were randomly assigned to treatment with 4 replicate pans/treatment. Plants were grown in an environmentally controlled room, and watered with the liquid treatment to keep fluid amount consistent in the pans. Plant height was recorded every 10 d. At the experiment's end (d 41), plants were harvested to determine plant DM biomass and TM content using ICP-MS. Biomass, final height and TM data were analyzed using ANOVA and growth rate data were analyzed using regression and orthogonal contrasts. The NUT and ORG plants had greater final DM biomass and height compared with WAT plants, while ING and CON were intermediate (P < 0.05). Growth was quadratic for WAT, with a plateau in growth at d 25. Growth in the remaining treatments was linear and rate was greatest for NUT, followed by ORG, lowest in CON, and ING did not differ from ORG and CON (P < 0.05). Cu and Mn was greatest in NUT (P < 0.05). Zn was lower in WAT compared with all treatments (P < 0.055) and Co and Se were not different among treatments (P > 0.05). The level and source of TM in horse diets affected plant availability of nutrients in the manure, which can influence pasture growth and composition.
    Keywords Festuca arundinacea ; biomass ; diet ; feces ; growth chambers ; horse manure ; horses ; hydroponics ; industry ; liquids ; mineral content ; nutrient solutions ; pastures ; plant height ; rockwool ; veterinary medicine
    Language English
    Dates of publication 2021-05
    Publishing place Elsevier Inc.
    Document type Article
    Note NAL-AP-2-clean
    ZDB-ID 2102631-2
    ISSN 1542-7412 ; 0737-0806
    ISSN (online) 1542-7412
    ISSN 0737-0806
    DOI 10.1016/j.jevs.2021.103561
    Database NAL-Catalogue (AGRICOLA)

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  6. Article: 77 Trace elements in whole blood and mane hair of horses fed varying sources and levels of trace elements

    Fowler, A.L / Hayes, S.H / Krebs, K / Brümmer-Holder, M

    Journal of equine veterinary science. 2021 May, v. 100

    2021  

    Abstract: There has been interest in using hair as a marker for mineral status in horses, but there is a lack of quality research to develop a method to do so. The objectives of this study were to determine if dietary supply of minerals would affect blood and mane ...

    Abstract There has been interest in using hair as a marker for mineral status in horses, but there is a lack of quality research to develop a method to do so. The objectives of this study were to determine if dietary supply of minerals would affect blood and mane hair element concentrations and if there would be a relationship between blood and mane hair element concentrations. Nine mature geldings were used in a replicated 3 × 3 Latin square design. All horses had ad libitum access to forage and 3 dietary treatments were provided by a soybean meal pellet: organic trace minerals (ORG), inorganic trace minerals (ING), and no added trace minerals (CON). The ING and ORG pellet provided the same amount of Co, Cu, Mn, Se, and Zn (between 100 and 380% of NRC requirements), but varied in source and CON provided levels of minerals between 15 and 170% of NRC requirements depending on the mineral. There were 3 21-d treatment periods, including a 5-d washout, so each horse received each treatment. Before the first period, a 3 to 4 cm section of mane hair at the poll was clipped close to the skin. On the last day of each treatment period, blood and mane hair were collected. Mane hair was clipped from the same poll area so only new hair growth was collected. Hair and blood were analyzed for Co, Cr, Cu, Mn, Se, Pb, and Zn using ICP-MS. Data were analyzed using ANOVA with treatment, period, and square replicate as effects. The effect of mane hair color on mineral concentration was evaluated using an ANOVA with hair color as the main effect (black, n = 5; chestnut, n = 3; 1 gray, not included). Means were separated using LSD test. Correlations between hair and blood elements were made using Pearson correlation coefficients. Blood Co tended to be lowest in CON compared with other treatments (P = 0.071). Blood Cr tended to be greatest (P = 0.107) and blood Se was greatest (P < 0.05) in ORG compared with CON, with ING not different from either group. Hair Co was greatest in ORG compared with ING, but CON was not different from either (P < 0.05). Hair Cr tended to be greatest in CON compared with ING, with ORG not different from either (P = 0.102). Hair Pb was greatest in CON compared with the other treatments (P < 0.05). The only correlation between blood and hair was a weak trend for blood Co to be correlated with hair Co (r = 0.347; P = 0.076). Across all treatments, black hair had greater concentrations of Se and lower concentrations of Zn than chestnut hair (P < 0.05). While this study did not find correlations between hair and blood, mineral level and source did alter blood and hair concentrations of certain elements independently, and hair color influences mineral deposition.
    Keywords Castanea ; blood ; color ; mineral content ; soybean meal ; veterinary medicine
    Language English
    Dates of publication 2021-05
    Publishing place Elsevier Inc.
    Document type Article
    Note NAL-AP-2-clean
    ZDB-ID 2102631-2
    ISSN 1542-7412 ; 0737-0806
    ISSN (online) 1542-7412
    ISSN 0737-0806
    DOI 10.1016/j.jevs.2021.103540
    Database NAL-Catalogue (AGRICOLA)

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  7. Article: Effect of weight change on markers of bone turnover and phosphorus excretion

    Fowler, A.L. / Pyles, M.B. / Hayes, S.H. / Crum, A.D. / Harris, P.A. / Krotky, A. / Lawrence, L.M.

    Journal of equine veterinary science. 2022 July 11,

    2022  

    Abstract: There is little information about how weight change in horses impacts bone turnover and the metabolism of minerals associated with bone. This study evaluated weight change in mature horses as a factor that could alter bone turnover and fecal P output. ... ...

    Abstract There is little information about how weight change in horses impacts bone turnover and the metabolism of minerals associated with bone. This study evaluated weight change in mature horses as a factor that could alter bone turnover and fecal P output. Fifteen horses (555±8 kg) were assigned to three treatments: weight loss (LO; n=5), weight maintenance (MA; n=5), and weight gain (GA; n=5). Diets contained 75%, 100%, and 145% of maintenance digestible energy requirements for the three treatments, respectively, but contained similar amounts of protein and minerals. At the end of the weight change period (27±6 d), blood samples were analyzed for bone biomarkers and a 5-day total fecal collection was conducted to measure fecal mineral output. Horses fed the MA diet had an average daily weight change that was not different from either the GA or LO treatments, while weight change was different between the GA group and the LO group (0.49 kg/d vs -1.16 kg/d; P=0.017). Weight change was negatively correlated with cross-linking C-terminal telopeptides of type-I collagen, a biomarker of bone resorption (r=-0.62; P=0.014) and tended to be positively correlated with bone alkaline phosphatase, a biomarker of bone formation (r=0.48; P=0.068). Also, fecal P output tended to be lower in GA than in LO horses (P=0.085), while MA was intermediate and not different, suggesting that weight loss was increasing bone resorption, resulting in a tendency for higher P loss from the body. Weight change in horses can influence bone metabolism as well as mineral excretion.
    Keywords alkaline phosphatase ; biomarkers ; blood ; bone formation ; bone resorption ; collagen ; crosslinking ; diet ; digestible energy ; excretion ; horses ; metabolism ; phosphorus ; veterinary medicine ; weight control ; weight gain ; weight loss
    Language English
    Dates of publication 2022-0711
    Publishing place Elsevier Inc.
    Document type Article
    Note Pre-press version
    ZDB-ID 2102631-2
    ISSN 1542-7412 ; 0737-0806
    ISSN (online) 1542-7412
    ISSN 0737-0806
    DOI 10.1016/j.jevs.2022.104080
    Database NAL-Catalogue (AGRICOLA)

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  8. Article ; Online: Covid 19 and Surgical training: Carpe Diem.

    Hennessy, O / Fowler, A L / Hennessy, C / Hogan, A / Nugent, E / Joyce, M

    The British journal of surgery

    2020  Volume 107, Issue 12, Page(s) e591

    MeSH term(s) COVID-19 ; Humans ; Pandemics ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-09-14
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2985-3
    ISSN 1365-2168 ; 0263-1202 ; 0007-1323 ; 1355-7688
    ISSN (online) 1365-2168
    ISSN 0263-1202 ; 0007-1323 ; 1355-7688
    DOI 10.1002/bjs.12032
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: 3 Weanling Thoroughbred mitochondrial profiles are related to race performance metrics

    Guy, C.P / Latham, C.M / Owen, R.N / Fowler, A.L / Fenger, C.K / Riley, D.G / White-Springer, S.H

    Journal of equine veterinary science. 2021 May, v. 100

    2021  

    Abstract: Few physiological markers have been identified to predict performance potential in juvenile horses. Within racing, performance is difficult to quantify due to variations in track conditions and participant caliber; metrics such as speed figures and ... ...

    Abstract Few physiological markers have been identified to predict performance potential in juvenile horses. Within racing, performance is difficult to quantify due to variations in track conditions and participant caliber; metrics such as speed figures and dosage profiles (DP) are used to overcome some of these challenges. To test the hypothesis that weanling mitochondrial profiles are associated with performance indices, gluteus medius samples were collected from racing-bred Thoroughbred weanlings (99 fillies, 90 colts; mean ± SD; 6.0 ± 0.6 mo) and analyzed for mitochondrial enzyme activities via colorimetry, and for oxidative (P) and electron transport (E) capacities via high-resolution respirometry. Dosage profiles, which include influence of speed and stamina, dosage index, and center of distribution were determined from each horse's pedigree. Associations were evaluated by regression of these dependent variables on mitochondrial profile measures. The mixed linear models included sex, year, farm, and the farm × year interaction as fixed effects; effects with significance of P > 0.2 were removed from each model. Sire was included as a random effect. Data are presented as regression coefficients ± SE. Dosage index was negatively associated with integrative (relative to mg tissue) P with complex I (PCI; −0.02 ± 0.01; P = 0.04), positively associated with intrinsic (relative to citrate synthase activity; CS) E with complex II only (ECII; 0.50 ± 0.21; P = 0.02), tended to be positively associated with intrinsic P with complexes I+II (PCI₊II; 0.26 ± 0.15) and intrinsic maximum E (ECI₊II; 0.24 ± 0.14; P ≤ 0.08), and tended to be negatively associated with the contribution of PCI to ECI₊II (−2.70 ± 1.47; P = 0.06). Stamina points were positively associated with CS activity (0.021 ± 0.008) and integrative PCI (0.011 ± 0.004; P ≤ 0.02), negatively related with intrinsic ECII (−0.23 ± 0.09; P = 0.02), and tended to be negatively related with intrinsic PCI₊II (−0.13 ± 0.07) and intrinsic ECI₊II (−0.12 ± 0.06; P ≤ 0.08). Racing records were available on a subset of horses (n = 30). The career-best speed figure for each horse was positively associated with integrative (relative to mg protein) mitochondrial function (cytochrome c oxidase activity; 1.83 ± 0.62; P = 0.006) and negatively related with integrative mitochondrial leak (−2.40 ± 1.13) and the contribution of leak to ECI₊II (−170.73 ± 68.61; P ≤ 0.05). Relationships between DP and mitochondrial phenotypes may offer insight into mitochondrial profiles of horses that are best suited for specific disciplines or specialties within a discipline, but these results should be confirmed in a larger cohort of horses.
    Keywords Thoroughbred ; citrate (si)-synthase ; colorimetry ; electron transfer ; farms ; juveniles ; mitochondria ; pedigree ; sires ; veterinary medicine ; weanlings
    Language English
    Dates of publication 2021-05
    Publishing place Elsevier Inc.
    Document type Article
    Note NAL-AP-2-clean
    ZDB-ID 2102631-2
    ISSN 1542-7412 ; 0737-0806
    ISSN (online) 1542-7412
    ISSN 0737-0806
    DOI 10.1016/j.jevs.2021.103466
    Database NAL-Catalogue (AGRICOLA)

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