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  1. Article ; Online: Highlights from ICOPA 2022.

    Frias, Liesbeth

    The Lancet. Microbe

    2022  Volume 3, Issue 11, Page(s) e813

    Language English
    Publishing date 2022-10-03
    Publishing country England
    Document type Journal Article
    ISSN 2666-5247
    ISSN (online) 2666-5247
    DOI 10.1016/S2666-5247(22)00285-3
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  2. Article: A call to strengthen local governance for preventing and mitigating global crises.

    Frias, Liesbeth / Guerrero-Sanchez, Sergio

    One health (Amsterdam, Netherlands)

    2023  Volume 16, Page(s) 100556

    Abstract: Deforestation and land conversion have dramatic consequences to biodiversity and disease emergence, but they are also deep-rooted in historical forces involved in environmental injustice. Global guidelines tackling global crises approach the problem ... ...

    Abstract Deforestation and land conversion have dramatic consequences to biodiversity and disease emergence, but they are also deep-rooted in historical forces involved in environmental injustice. Global guidelines tackling global crises approach the problem using top-down formulas that often fail to match local needs and priorities, and are rarely evaluated for local suitability, implications, and impacts. Motivated by the report of the Intergovernmental Platform on Biodiversity and Ecosystem Services (IPBES) workshop, published in 2020, we reflect on how drivers of zoonotic disease emergence are linked to historical injustices and how global initiatives tackling global crises are prone to reproducing colonial structures. We provide examples of local governance strengthening through horizontal and interdisciplinary collaborations, and how the support of local solutions can build resilience against global crises.
    Language English
    Publishing date 2023-05-01
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2834831-X
    ISSN 2352-7714
    ISSN 2352-7714
    DOI 10.1016/j.onehlt.2023.100556
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  3. Article ; Online: Linguatula serrata.

    Frias, Liesbeth / Jenkins, David J

    Trends in parasitology

    2023  Volume 40, Issue 1, Page(s) 89–90

    MeSH term(s) Animals ; Pentastomida ; Parasitic Diseases, Animal
    Language English
    Publishing date 2023-10-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 2036227-4
    ISSN 1471-5007 ; 1471-4922
    ISSN (online) 1471-5007
    ISSN 1471-4922
    DOI 10.1016/j.pt.2023.09.007
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  4. Article ; Online: Early detection of new pandemic waves. Control chart and a new surveillance index.

    Cildoz, Marta / Gaston, Martin / Frias, Laura / Garcia-Vicuña, Daniel / Azcarate, Cristina / Mallor, Fermin

    PloS one

    2024  Volume 19, Issue 2, Page(s) e0295242

    Abstract: The COVID-19 pandemic highlights the pressing need for constant surveillance, updating of the response plan in post-peak periods and readiness for the possibility of new waves of the pandemic. A short initial period of steady rise in the number of new ... ...

    Abstract The COVID-19 pandemic highlights the pressing need for constant surveillance, updating of the response plan in post-peak periods and readiness for the possibility of new waves of the pandemic. A short initial period of steady rise in the number of new cases is sometimes followed by one of exponential growth. Systematic public health surveillance of the pandemic should signal an alert in the event of change in epidemic activity within the community to inform public health policy makers of the need to control a potential outbreak. The goal of this study is to improve infectious disease surveillance by complementing standardized metrics with a new surveillance metric to overcome some of their difficulties in capturing the changing dynamics of the pandemic. At statistically-founded threshold values, the new measure will trigger alert signals giving early warning of the onset of a new pandemic wave. We define a new index, the weighted cumulative incidence index, based on the daily new-case count. We model the infection spread rate at two levels, inside and outside homes, which explains the overdispersion observed in the data. The seasonal component of real data, due to the public surveillance system, is incorporated into the statistical analysis. Probabilistic analysis enables the construction of a Control Chart for monitoring index variability and setting automatic alert thresholds for new pandemic waves. Both the new index and the control chart have been implemented with the aid of a computational tool developed in R, and used daily by the Navarre Government (Spain) for virus propagation surveillance during post-peak periods. Automated monitoring generates daily reports showing the areas whose control charts issue an alert. The new index reacts sooner to data trend changes preluding new pandemic waves, than the standard surveillance index based on the 14-day notification rate of reported COVID-19 cases per 100,000 population.
    MeSH term(s) Humans ; Pandemics/prevention & control ; COVID-19/epidemiology ; Public Health Surveillance ; Disease Outbreaks/prevention & control ; Records
    Language English
    Publishing date 2024-02-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0295242
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  5. Article: The

    Guerrero-Sanchez, Sergio / Frias, Liesbeth / Saimin, Silvester / Orozco-terWengel, Pablo / Goossens, Benoit

    Conservation physiology

    2023  Volume 11, Issue 1, Page(s) coad055

    Abstract: Agricultural expansion in Southeast Asia has converted most natural landscapes into mosaics of forest interspersed with plantations, dominated by the presence of generalist species that benefit from resource predictability. Dietary shifts, however, can ... ...

    Abstract Agricultural expansion in Southeast Asia has converted most natural landscapes into mosaics of forest interspersed with plantations, dominated by the presence of generalist species that benefit from resource predictability. Dietary shifts, however, can result in metabolic alterations and the exposure of new parasites that can impact animal fitness and population survival. Our study focuses on the Asian water monitor lizard (
    Language English
    Publishing date 2023-08-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 2721508-8
    ISSN 2051-1434
    ISSN 2051-1434
    DOI 10.1093/conphys/coad055
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  6. Article ; Online: Retrospective Study of First Trimester Metrorrhagia: Pregnancy Follow-Up and Relationship with the Appearance of Gestational Complications.

    Baños Cándenas, Laura / Abehsera Davó, Daniel / Castaño Frías, Lucía / González Mesa, Ernesto

    Medicina (Kaunas, Lithuania)

    2023  Volume 59, Issue 8

    Abstract: Background and ... ...

    Abstract Background and Objectives
    MeSH term(s) Pregnancy ; Infant, Newborn ; Female ; Humans ; Aged ; Metrorrhagia/etiology ; Retrospective Studies ; Diabetes, Gestational ; Pre-Eclampsia ; Pregnancy Trimester, First ; Follow-Up Studies
    Language English
    Publishing date 2023-07-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina59081370
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  7. Article ; Online: Detection of echinostomatid trematode eggs at the forest-oil palm interface in Sabah, Malaysia.

    Frias, Liesbeth / Manin, Benny Obrain / Guerrero-Sánchez, Sergio / Sipangkui, Symphorosa / Chua, Tock H

    Parasitology

    2023  Volume 151, Issue 2, Page(s) 181–184

    Abstract: In this study, we report the occurrence of echinostomatid eggs in feces of wildlife, domestic animals and humans frequenting the forest–oil palm plantation interface in the Kinabatangan (Sabah, Malaysia), and discuss potential implications for public ... ...

    Abstract In this study, we report the occurrence of echinostomatid eggs in feces of wildlife, domestic animals and humans frequenting the forest–oil palm plantation interface in the Kinabatangan (Sabah, Malaysia), and discuss potential implications for public health. Using microscopy, we detected echinostomatid eggs in six host species, including Asian palm civets (
    MeSH term(s) Humans ; Animals ; Cats ; Dogs ; Malaysia/epidemiology ; Ecosystem ; Trematoda ; Forests ; Echinostoma ; Animals, Wild ; Macaca fascicularis ; Zoonoses
    Language English
    Publishing date 2023-12-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 207627-5
    ISSN 1469-8161 ; 0031-1820
    ISSN (online) 1469-8161
    ISSN 0031-1820
    DOI 10.1017/S0031182023001257
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  8. Article ; Online: Omissions in the synthetic theory of evolution.

    Frías L, Daniel

    Biological research

    2010  Volume 43, Issue 3, Page(s) 299–306

    Abstract: The Synthetic Theory of Evolution is the most unifying theory of life science. This theory has dominated scientific thought in explaining the mechanisms involved in speciation. However, there are some omissions that have delayed the understanding of some ...

    Abstract The Synthetic Theory of Evolution is the most unifying theory of life science. This theory has dominated scientific thought in explaining the mechanisms involved in speciation. However, there are some omissions that have delayed the understanding of some aspects of the mechanisms of organic evolution, principally: 1) the bridge between somatic and germinal cells, especially in some phylum of invertebrates and vertebrates; 2) horizontal genetic transferences and the importance of viruses in host adaptation and evolution; 3) the role of non-coding DNA and non-transcriptional genes; 4) homeotic evolution and the limitations of gradual evolution; and 5) excessive emphasis on extrinsic barriers to animal speciation. This paper reviews each of these topics in an effort to contribute to a better comprehension of organic evolution. Molecular findings suggest the need for a new evolutionary synthesis.
    MeSH term(s) Animals ; Biological Evolution ; Epigenesis, Genetic/genetics ; Genetics, Population ; Host-Pathogen Interactions/genetics ; Humans ; Invertebrates/genetics ; Phylogeny ; Selection, Genetic/genetics ; Vertebrates/genetics ; Viruses/genetics
    Language English
    Publishing date 2010
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 1138990-4
    ISSN 0717-6287 ; 0716-9760
    ISSN (online) 0717-6287
    ISSN 0716-9760
    DOI /S0716-97602010000300006
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  9. Article: Surgical Interest of an Accurate Real-World Prediction of Primary Systemic Therapy Response in HER2 Breast Cancers.

    Sánchez-Méndez, Jose Ignacio / Horstmann, Mónica / Méndez, Nieves / Frías, Laura / Moreno, Elisa / Yébenes, Laura / Roca, Mᵃ José / Hernández, Alicia / Martí, Covadonga

    Cancers

    2023  Volume 15, Issue 10

    Abstract: Human epidermal growth factor receptor 2 (HER2)-enriched breast cancers (BC) present the highest rates of pathological response to primary systemic therapy (PST), but they are also the ones that tend to be larger at diagnosis, with microcalcifications ... ...

    Abstract Human epidermal growth factor receptor 2 (HER2)-enriched breast cancers (BC) present the highest rates of pathological response to primary systemic therapy (PST), but they are also the ones that tend to be larger at diagnosis, with microcalcifications and, often, with axillary involvement. If we do not have a reliable method to predict the degree of response, we may not be able to transfer the benefits of PST to surgery. The post-PST surgery planning is guided by the findings in the magnetic resonance imaging (MRI), whose predictive capacity, although high, is far from optimal. Thus, it seems interesting to find other variables to improve it. A retrospective observational study including women with HER2 BC treated with PST and further surgery was conducted. Information regarding clinical, radiological, and histopathological variables was gathered from a total of 132 patients included. Radiological complete response (rCR) was achieved in 65.9% of the sample, and pathological complete response (pCR), according to Miller and Payne criteria, in 58.3% of cases. A higher Ki67 value, the absence of Hormonal Receptors expression, and an rCR was significantly related to a pCR finding. This information impacts directly in surgery planning, as it permits adjustment of the breast resection volume.
    Language English
    Publishing date 2023-05-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers15102757
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  10. Article ; Online: Usefulness of lipid emulsion for the management of cardiac toxicity in acute flecainide overdose.

    Tuero León, Gaspar / González, Jesús / González, Néstor / Gomila Muñiz, Isabel / Sahuquillo Frías, Laura / Barceló Martín, Bernardino

    Emergencias : revista de la Sociedad Espanola de Medicina de Emergencias

    2023  Volume 35, Issue 4, Page(s) 318–319

    Title translation Utilidad de la emulsión lipídica en el tratamiento de la toxicidad cardiaca en una intoxicación aguda por flecainida.
    MeSH term(s) Humans ; Cardiotoxicity ; Flecainide ; Emulsions ; Lipids
    Chemical Substances Flecainide (K94FTS1806) ; Emulsions ; Lipids
    Language Spanish
    Publishing date 2023-07-10
    Publishing country Spain
    Document type Letter
    ZDB-ID 2127173-2
    ISSN 2386-5857 ; 2386-5857
    ISSN (online) 2386-5857
    ISSN 2386-5857
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