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  1. Article ; Online: Effect of Different Post-Curing Methods on the Degree of Conversion of 3D-Printed Resin for Models in Dentistry.

    Kirby, Scott / Pesun, Igor / Nowakowski, Anthony / França, Rodrigo

    Polymers

    2024  Volume 16, Issue 4

    Abstract: The aim was to investigate the effects of different post-curing units on the chemical properties (degree of conversion) of 3D-printed resins for producing models in dentistry. The goal is to determine whether less-expensive post-curing units can be a ... ...

    Abstract The aim was to investigate the effects of different post-curing units on the chemical properties (degree of conversion) of 3D-printed resins for producing models in dentistry. The goal is to determine whether less-expensive post-curing units can be a viable alternative to the manufacturer's recommended units. Forty-five samples were fabricated with an LCD printer (Phrozen Sonic Mini, Phrozen 3D, Hsinchu City, Taiwan) using MSLA Dental Modeling Resin (Apply Lab Work, Torrance, CA, USA). These samples were divided randomly into four different groups for post-curing using four distinct curing units: Phrozen Cure V2 (Phrozen 3D, Hsinchu City, Taiwan), a commercial acrylic nail UV LED curing unit (SUNUV, Shenzhen, China), a homemade curing unit created from a readily available UV LED light produced (Shenzhen, China), and the Triad
    Language English
    Publishing date 2024-02-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym16040549
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Drug-delivery nanoparticles for bone-tissue and dental applications.

    Higino, Taisa / França, Rodrigo

    Biomedical physics & engineering express

    2022  Volume 8, Issue 4

    Abstract: The use of nanoparticles as biomaterials with applications in the biomedical field is growing every day. These nanomaterials can be used as contrast imaging agents, combination therapy agents, and targeted delivery systems in medicine and dentistry. ... ...

    Abstract The use of nanoparticles as biomaterials with applications in the biomedical field is growing every day. These nanomaterials can be used as contrast imaging agents, combination therapy agents, and targeted delivery systems in medicine and dentistry. Usually, nanoparticles are found as synthetic or natural organic materials, such as hydroxyapatite, polymers, and lipids. Besides that, they are could also be inorganic, for instance, metallic or metal-oxide-based particles. These inorganic nanoparticles could additionally present magnetic properties, such as superparamagnetic iron oxide nanoparticles. The use of nanoparticles as drug delivery agents has many advantages, for they help diminish toxicity effects in the body since the drug dose reduces significantly, increases drugs biocompatibility, and helps target drugs to specific organs. As targeted-delivery agents, one of the applications uses nanoparticles as drug delivery particles for bone-tissue to treat cancer, osteoporosis, bone diseases, and dental treatments such as periodontitis. Their application as drug delivery agents requires a good comprehension of the nanoparticle properties and composition, alongside their synthesis and drug attachment characteristics. Properties such as size, shape, core-shell designs, and magnetic characteristics can influence their behavior inside the human body and modify magnetic properties in the case of magnetic nanoparticles. Based on that, many different studies have modified the synthesis methods for these nanoparticles and developed composite systems for therapeutics delivery, adapting, and improving magnetic properties, shell-core designs, and particle size and nanosystems characteristics. This review presents the most recent studies that have been presented with different nanoparticle types and structures for bone and dental drug delivery.
    MeSH term(s) Contrast Media ; Drug Delivery Systems/methods ; Humans ; Magnetics ; Nanoparticles/chemistry ; Particle Size
    Chemical Substances Contrast Media
    Language English
    Publishing date 2022-05-06
    Publishing country England
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ISSN 2057-1976
    ISSN (online) 2057-1976
    DOI 10.1088/2057-1976/ac682c
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  3. Article ; Online: Understanding thiopurine methyltransferase polymorphisms for the targeted treatment of hematologic malignancies.

    Franca, R / Braidotti, S / Stocco, G / Decorti, G

    Expert opinion on drug metabolism & toxicology

    2021  Volume 17, Issue 10, Page(s) 1187–1198

    Abstract: Introduction: Thiopurine methyltransferase (TPMT) catalyzes the S-methylation of thiopurines (mercaptopurine (MP) and tioguanine (TG)), chemotherapeutic agents used in the treatment of acute lymphoblastic leukemia (ALL). Polymorphisms in : Areas ... ...

    Abstract Introduction: Thiopurine methyltransferase (TPMT) catalyzes the S-methylation of thiopurines (mercaptopurine (MP) and tioguanine (TG)), chemotherapeutic agents used in the treatment of acute lymphoblastic leukemia (ALL). Polymorphisms in
    Areas covered: This review gives an overview on
    Expert opinion: To titrate thiopurines safely and effectively, achieve the right degree of lymphotoxic effect and avoid excessive myelosuppression, the optimal management will combine a preemptive
    MeSH term(s) Animals ; Antimetabolites, Antineoplastic/administration & dosage ; Antimetabolites, Antineoplastic/adverse effects ; Antimetabolites, Antineoplastic/pharmacokinetics ; Genotype ; Humans ; Mercaptopurine/administration & dosage ; Mercaptopurine/adverse effects ; Mercaptopurine/pharmacokinetics ; Methyltransferases/genetics ; Methyltransferases/metabolism ; Molecular Targeted Therapy ; Polymorphism, Genetic ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/drug therapy ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/enzymology ; Thioguanine/administration & dosage ; Thioguanine/adverse effects ; Thioguanine/pharmacokinetics
    Chemical Substances Antimetabolites, Antineoplastic ; Mercaptopurine (E7WED276I5) ; Methyltransferases (EC 2.1.1.-) ; thiopurine methyltransferase (EC 2.1.1.67) ; Thioguanine (FTK8U1GZNX)
    Language English
    Publishing date 2021-09-06
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2214462-6
    ISSN 1744-7607 ; 1742-5255
    ISSN (online) 1744-7607
    ISSN 1742-5255
    DOI 10.1080/17425255.2021.1974398
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6264: Show issues Location:
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  4. Article ; Online: Contributions from the Global Emerging Infections Surveillance (GEIS) network.

    Jones, Franca R

    MSMR

    2018  Volume 25, Issue 8, Page(s) 2–4

    MeSH term(s) Communicable Disease Control ; Humans ; Military Personnel/statistics & numerical data ; Occupational Diseases/epidemiology ; Occupational Diseases/microbiology ; Population Surveillance ; United States/epidemiology
    Language English
    Publishing date 2018-08-23
    Publishing country United States
    Document type Introductory Journal Article
    ZDB-ID 2623409-9
    ISSN 2152-8217 ; 2158-0111
    ISSN (online) 2152-8217
    ISSN 2158-0111
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  5. Article ; Online: Evaluation of Glazing and Polishing Systems for Novel Chairside CAD/CAM Lithium Disilicate and Virgilite Crowns.

    Jurado, C A / Arndt, K / Azpiazu-Flores, F X / Faddoul, F / França, R / Fischer, N G / Watanabe, H

    Operative dentistry

    2023  Volume 48, Issue 6, Page(s) 689–699

    Abstract: Objective: The purpose of this study was to evaluate the effectiveness of glazing, two zirconia, and two lithium disilicate polishing systems on surface roughness of a CAD/CAM lithium disilicate and virgilite ceramic with atomic force microscopy (AFM) ... ...

    Abstract Objective: The purpose of this study was to evaluate the effectiveness of glazing, two zirconia, and two lithium disilicate polishing systems on surface roughness of a CAD/CAM lithium disilicate and virgilite ceramic with atomic force microscopy (AFM) and visual assessment performed by dental students and faculty.
    Methods and materials: Sixty maxillary right central incisor crowns made of a novel chairside CAD/CAM lithium disilicate and virgilite (CEREC Tessera) were milled for glazing and polishing. The crowns were divided into six groups: no polishing/glazing provided (NoP/G); glazed (GZ); glazed and polished with Brasseler Dialite LD Lithium Disilicate (DiLD); glazed and polished with Meisinger Luster Lithium Disilicate (LuLD); glazed and polished with Brasseler Dialite ZR Zirconia (DiZR); and glazed and polished with Meisinger Luster Zirconia (LuZR). Surfaces were scanned with AFM to measure roughness (Ra) and root mean square roughness (Rq) and generate micrographs. Crowns were visually assessed by 10 dental students and 10 dental school faculty members to determine clinical acceptableness.
    Results: Glazing and all polishing kits significantly reduced Ra and Rq compared to no polishing/glazing. No significant Ra differences were found between glazing and all polishing kits (p>0.05). DiZR significantly reduced Rq compared to other groups (p<0.05). Visual assessment showed that GZ, LuLD, and DiZR were the most clinically acceptable crowns.
    Conclusion: Polishing and glazing considerably improve the surface smoothness of maxillary central incisor crowns fabricated out of a chairside CAD/CAM lithium disilicate and virgilite ceramic. Altogether, zirconia polishing systems provided smoother and more clinically acceptable surfaces than the lithium disilicate kits.
    MeSH term(s) Humans ; Materials Testing ; Dental Polishing/methods ; Surface Properties ; Dental Porcelain ; Ceramics ; Crowns ; Computer-Aided Design ; Microscopy, Electron, Scanning
    Chemical Substances lithia disilicate ; zirconium oxide (S38N85C5G0) ; Dental Porcelain (12001-21-7)
    Language English
    Publishing date 2023-10-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 752995-8
    ISSN 1559-2863 ; 0361-7734
    ISSN (online) 1559-2863
    ISSN 0361-7734
    DOI 10.2341/23-017-L
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    In stock of ZB MED Cologne/Königswinter

    Zs.B 1963: Show issues Location:
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  6. Article: XPS Characterization of TiO

    Konatu, Reginaldo Toshihiro / Domingues, Danielle Duque / França, Rodrigo / Alves, Ana Paula Rosifini

    Journal of functional biomaterials

    2023  Volume 14, Issue 7

    Abstract: Ti15Zr15Mo (TMZ alloy) has been studied in recent years for biomedical applications, mainly due to phase beta formation. From the surface modification, it is possible to associate the volume and surface properties with a better biomedical response. This ... ...

    Abstract Ti15Zr15Mo (TMZ alloy) has been studied in recent years for biomedical applications, mainly due to phase beta formation. From the surface modification, it is possible to associate the volume and surface properties with a better biomedical response. This study aimed to evaluate the possibility of using anodization to obtain TiO
    Language English
    Publishing date 2023-07-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2648525-4
    ISSN 2079-4983
    ISSN 2079-4983
    DOI 10.3390/jfb14070353
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  7. Article ; Online: Metal distributions in human hair strand cross-section: Advanced analysis using LA-ICP-MS in dentistry.

    Fernandes, Ana Carla B C J / Yang, Panseok / Armstrong, Debbie / França, Rodrigo

    Talanta

    2023  Volume 265, Page(s) 124909

    Abstract: Human hair is a biomarker that is crucial in investigating toxic metal exposures. Thirteen elements (Li, Mg, Cr, Mn, Fe, Co, Ni, Cu, Zn, Sr, Ag, Ba, and Hg) commonly found in hair strands from dentistry environments were investigated using laser ablation ...

    Abstract Human hair is a biomarker that is crucial in investigating toxic metal exposures. Thirteen elements (Li, Mg, Cr, Mn, Fe, Co, Ni, Cu, Zn, Sr, Ag, Ba, and Hg) commonly found in hair strands from dentistry environments were investigated using laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS). Previous studies have employed partial ablation along hair strands to avoid contamination from mounting materials. The partial ablation can be problematic if element chemistry within the hair is not homogeneous. In this study, element variations along cross-sections of human hair strands were investigated. A number of elements showed internal variations with most elements enriched at the cuticle, emphasizing the importance of complete ablation for the characterization of human hair element chemistry. Complete and partial ablation LA-ICP-MS results were verified against solution nebulization SN-ICP-MS. Complete LA-ICP-MS showed a better agreement with SN-ICP-MS. Therefore, the developed LA-ICP-MS method can be applied to monitor the health of dental workers and students exposed to dental environments.
    MeSH term(s) Humans ; Metals/analysis ; Laser Therapy ; Mercury/analysis ; Hair/chemistry ; Dentistry
    Chemical Substances Metals ; Mercury (FXS1BY2PGL)
    Language English
    Publishing date 2023-07-03
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1500969-5
    ISSN 1873-3573 ; 0039-9140
    ISSN (online) 1873-3573
    ISSN 0039-9140
    DOI 10.1016/j.talanta.2023.124909
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  8. Article: Optimizing semen cryopreservation in Calomys laucha: a step forward in rodent reproductive research.

    Corcini, C D / Vilela, J / Gatti, N / Mion, B / Castro, N / Franca, R T / Varela Junior, A S

    Cryo letters

    2024  Volume 45, Issue 2, Page(s) 134–138

    Abstract: Background: Examining semen cryopreservation in Calomys laucha offers valuable insights for reproductive research and species conservation.: Objective: To determine the most effective sugar for the cryopreservation of C. laucha semen.: Materials ... ...

    Abstract Background: Examining semen cryopreservation in Calomys laucha offers valuable insights for reproductive research and species conservation.
    Objective: To determine the most effective sugar for the cryopreservation of C. laucha semen.
    Materials and methods: Using 36 epididymides from C. laucha, semen samples were diluted in a 3% skimmed milk medium supplemented with one of four sugars (glucose, fructose, lactose, or sucrose) at a concentration of 0.3 M. These mixtures underwent a conditioning phase at 37 degree C for 10 min, cooled to -80 degree C for another 10 min, and were subsequently stored in liquid nitrogen.
    Results: Upon thawing, samples treated with lactose and glucose solutions show superior sperm motility, achieving 8.2% and 10.0% respectively, in contrast to the fructose (2.0%) and sucrose (4.1%) mixtures. Furthermore, samples preserved in glucose registered the highest sperm penetration rates, reaching 44.9%.
    Conclusion: Our findings suggest that a cryopreservation medium containing 0.3 M glucose can contribute to the safeguarding C. laucha rodent semen. https://doi.org/10.54680/fr24210110612.
    MeSH term(s) Animals ; Male ; Semen ; Cryopreservation ; Lactose ; Rodentia ; Sperm Motility ; Semen Preservation ; Glucose/pharmacology ; Fructose ; Sucrose/pharmacology ; Spermatozoa ; Cryoprotective Agents
    Chemical Substances Lactose (J2B2A4N98G) ; Glucose (IY9XDZ35W2) ; Fructose (30237-26-4) ; Sucrose (57-50-1) ; Cryoprotective Agents
    Language English
    Publishing date 2024-04-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 756781-9
    ISSN 0143-2044
    ISSN 0143-2044
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6449: Show issues Location:
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  9. Article ; Online: Biomaterials in bone and mineralized tissue engineering using 3D printing and bioprinting technologies.

    Rahimnejad, Maedeh / Rezvaninejad, Raziyehsadat / Rezvaninejad, Rayehehossadat / França, Rodrigo

    Biomedical physics & engineering express

    2021  Volume 7, Issue 6

    Abstract: This review focuses on recently developed printable biomaterials for bone and mineralized tissue engineering. 3D printing or bioprinting is an advanced technology to design and fabricate complex functional 3D scaffolds, mimicking native tissue ... ...

    Abstract This review focuses on recently developed printable biomaterials for bone and mineralized tissue engineering. 3D printing or bioprinting is an advanced technology to design and fabricate complex functional 3D scaffolds, mimicking native tissue for
    MeSH term(s) Biocompatible Materials ; Bioprinting ; Hydrogels ; Printing, Three-Dimensional ; Tissue Engineering ; Tissue Scaffolds
    Chemical Substances Biocompatible Materials ; Hydrogels
    Language English
    Publishing date 2021-10-07
    Publishing country England
    Document type Journal Article ; Review
    ISSN 2057-1976
    ISSN (online) 2057-1976
    DOI 10.1088/2057-1976/ac21ab
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  10. Article: The Effect of Vitamin D Adequacy on Thyroid Hormones and Inflammatory Markers after Bariatric Surgery.

    França, Roberta / Cordeiro, Adryana / Pereira, Silvia Elaine / Saboya, Carlos José / Ramalho, Andrea

    Metabolites

    2023  Volume 13, Issue 5

    Abstract: Vitamin D status affects the clinical and corporal outcomes of postoperative patients who undergo a Roux-en-Y gastric bypass (RYGB). The aim of this study was to evaluate the effect of adequate vitamin D serum concentrations on thyroid hormones, body ... ...

    Abstract Vitamin D status affects the clinical and corporal outcomes of postoperative patients who undergo a Roux-en-Y gastric bypass (RYGB). The aim of this study was to evaluate the effect of adequate vitamin D serum concentrations on thyroid hormones, body weight, blood cell count, and inflammation after an RYGB. A prospective observational study was conducted with eighty-eight patients from whom we collected blood samples before and 6 months after surgery to evaluate their levels of 25-hydroxyvitamin D 25(OH)D, thyroid hormones, and their blood cell count. Their body weight, body mass index (BMI), total weight loss, and excess weight loss were also evaluated 6 and 12 months after surgery. After 6 months, 58% of the patients achieved an adequate vitamin D nutritional status. Patients in the adequate group showed a decrease in the concentration of thyroid-stimulating hormone (TSH) (3.01 vs. 2.22 µUI/mL,
    Language English
    Publishing date 2023-04-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662251-8
    ISSN 2218-1989
    ISSN 2218-1989
    DOI 10.3390/metabo13050603
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