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  1. Article ; Online: End of life management in Internal Medicine Wards

    Veronica Stefanelli / Niccolò Veneziani / Diletta Calamassi / Piero Morino / Sandra Niccolini / Francesca Dainelli / Francesca Maggi / Anna Marchese / Luca Masotti

    Italian Journal of Medicine (2020)

    a single centre real life report

    2020  

    Abstract: The burden of end of life in Internal Medicine wards is not neglegible. However, literature evidence about end of life care in Internal Medicine wards lacks. Therefore, the aim of this study was to report on end of life management in a Internal Medicine ... ...

    Abstract The burden of end of life in Internal Medicine wards is not neglegible. However, literature evidence about end of life care in Internal Medicine wards lacks. Therefore, the aim of this study was to report on end of life management in a Internal Medicine ward. We performed a retrospective study focusing on characteristics and management of patients consecutively died in an italian Internal Medicine ward between 2018, July-1 and 2019, June-30. Demographic, co-morbidity, pharmacological treatment at hospital admission and in the last 48- hours of life and procedures during hospital stay were collected. Study population was composed by 354 patients (190 females), corresponding to about ten percent of patients admitted in the ward, with mean age ± DS 83.5 ± 10.6 years. Eighty-four percent of deaths was exepected in the last 48 hours before exitus. The main co-morbidities were blood hypertension (66.3 %), solid or haematological malignancies (40.3%), arhythmias (34.7%), pressure ulcers (31.3%) and diabetes (27.4%). The main causes of hospitalization were infectious diseases (23.1%) and cardiac or respiratory failure (20.9%). In seven percent of patients palliative cares had been already activated before the hospital admission. No patient had written living wills or advance directives. In the last 48 hours of life, the main phramacological classes prescribed were opioids (63.2%), antibiotics (46.9%) and corticosteroids (46.3%). Compared with pharmacological classes prescribed at hospital admission, in the last 48 hours of life the prescription of antibiotics, corticosteroids, opioids and benzodiazepines was significantly increased, whereas the prescription of antihypertensive agents, proton pump inhibitors and antithrombotic drugs resulted significantly reduced. Written order to withdrawal of vital parameters relevation or active treatment were found in 30.7% and 31.9%, respectively. In the last 48 hours of life, 61% of patients underwent to at least one blood assay, 34% arterial blood gas analysis and about 35% at ...
    Keywords End of life ; palliative care ; internal medicine ; deaths ; elderly ; cancer ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2020-10-01T00:00:00Z
    Publisher PAGEPress Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: New-onset type 1 diabetes mellitus triggered by SARS-CoV-2 infection in a patient with Hashimoto thyroiditis

    Elena Schipani / Andrea Cozzi / Giuseppe Salvatore Murgida / Valentina Francolini / Eleonora Sisti / Stefania Di Martino / Francesca Dainelli / Rosa Vecchio / Elisa Grifoni / Luca Masotti

    Italian Journal of Medicine, Iss AOP (2021)

    a case report

    2021  

    Abstract: New onset type 1 diabetes mellitus is an uncommon but possible complication triggered by SARSCoV- 2 infection. Metabolic inflammation supported by cytokine storm leading to pancreatic beta cells destruction is the most probable link between COVID-19 and ... ...

    Abstract New onset type 1 diabetes mellitus is an uncommon but possible complication triggered by SARSCoV- 2 infection. Metabolic inflammation supported by cytokine storm leading to pancreatic beta cells destruction is the most probable link between COVID-19 and diabetes. Here, we describe the case of a 51-year-old female suffering from Hashimoto thyroiditis, who came to our attenction for new onset polyuria-polydipsia syndrome associated to hyperglycemia after a mild form of COVID- 19 recognized two months before and already recovered. Type 1 diabetes was diagnosed.
    Keywords Diabetes ; SARS-CoV-2 ; COVID-19 ; hyperglycemia ; glutamic acid decarboxylase-65 autoantibodies ; Medicine ; R
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher PAGEPress Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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