LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 756

Search options

  1. Article: Transient hemi-parkinsonism due to deep brain venous edema induced by severe intracranial hypotension, a case report.

    Frachet, S / Girault, S / François, B / Magy, L

    Revue neurologique

    2023  Volume 179, Issue 9, Page(s) 1041–1044

    Language English
    Publishing date 2023-10-08
    Publishing country France
    Document type Letter
    ZDB-ID 4593-7
    ISSN 2213-0004 ; 0035-3787
    ISSN (online) 2213-0004
    ISSN 0035-3787
    DOI 10.1016/j.neurol.2023.07.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ui II Zs.45: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article: Influence of winter North-Atlantic Oscillation on Climate-Related-Energy penetration in Europe

    François, B

    Renewable energy. 2016 Dec., v. 99

    2016  

    Abstract: When considering 100% renewable scenarios, backup generation is needed for stabilizing the network when Climate Related Energy (CRE) such as wind, solar or run-of-the river hydropower are not sufficient for supplying the load. Several studies show that, ... ...

    Abstract When considering 100% renewable scenarios, backup generation is needed for stabilizing the network when Climate Related Energy (CRE) such as wind, solar or run-of-the river hydropower are not sufficient for supplying the load. Several studies show that, over relatively short time period (less than 10 years), backup generation needs are reduced by dissipating power densities either in space through grids or time through storage. This study looks at the impact of low time frequency variations of CRE with a specific focus on the time variability induced by the North Atlantic Oscillation (NAO) teleconnection pattern during winter season. A set of eleven regions in Europe and Tunisia is used for highlighting space variability of the winter NAO’s impact. For each of these regions, we combine data from the Weather Research and Forecasting Model and the European Climate Assessment & Dataset for estimating solar-power, wind-power, run-of-the-river hydro-power and the energy load over the 1980–2012 time period. Results show that NAO’s impact on winter penetration rate depends on both the considered energy source and the location. They also highlight a non-linear relation between the NAO’s impact on CRE penetration rates and the level of equipment used for harvesting the CRE sources.
    Keywords climate ; data collection ; energy conversion ; environmental assessment ; equipment ; harvesting ; North Atlantic Oscillation ; rivers ; water power ; weather research and forecasting model ; wind ; wind power ; winter ; Europe ; Tunisia
    Language English
    Dates of publication 2016-12
    Size p. 602-613.
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 2001449-1
    ISSN 0960-1481
    ISSN 0960-1481
    DOI 10.1016/j.renene.2016.07.010
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: Addressing Parental Stress and Reducing Avoidable Benzodiazepine Exposure in Children During Hospitalization in Pediatric Intensive Care Units to Improve Mental Health Outcomes.

    Fernandez, Arnaud / Gindt, Morgane / Francois, Bérangère / Askenazy, Florence

    Indian journal of pediatrics

    2023  Volume 90, Issue 7, Page(s) 735

    MeSH term(s) Humans ; Child ; Benzodiazepines/adverse effects ; Hospitalization ; Intensive Care Units, Pediatric ; Parents/psychology ; Outcome Assessment, Health Care
    Chemical Substances Benzodiazepines (12794-10-4)
    Language English
    Publishing date 2023-04-24
    Publishing country India
    Document type Letter
    ZDB-ID 218231-2
    ISSN 0973-7693 ; 0019-5456
    ISSN (online) 0973-7693
    ISSN 0019-5456
    DOI 10.1007/s12098-023-04608-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 826: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Transcriptional Regulation of the Human 5-HT1A Receptor Gene by Lithium: Role of Deaf1 and GSK3β.

    Harkin, Emerson F / Nasrallah, Georges / Le François, Brice / Albert, Paul R

    International journal of molecular sciences

    2023  Volume 24, Issue 21

    Abstract: Serotonin 1A (5-HT1A) autoreceptors located on serotonin neurons inhibit their activity, and their upregulation has been implicated in depression, suicide and resistance to antidepressant treatment. Conversely, post-synaptic 5-HT1A heteroreceptors are ... ...

    Abstract Serotonin 1A (5-HT1A) autoreceptors located on serotonin neurons inhibit their activity, and their upregulation has been implicated in depression, suicide and resistance to antidepressant treatment. Conversely, post-synaptic 5-HT1A heteroreceptors are important for antidepressant response. The transcription factor deformed epidermal autoregulatory factor 1 (Deaf1) acts as a presynaptic repressor and postsynaptic enhancer of 5-HT1A transcription, but the mechanism is unclear. Because Deaf1 interacts with and is phosphorylated by glycogen synthase kinase 3β (GSK3β)-a constitutively active protein kinase that is inhibited by the mood stabilizer lithium at therapeutic concentrations-we investigated the role of GSK3β in Deaf1 regulation of human 5-HT1A transcription. In 5-HT1A promoter-reporter assays, human HEK293 kidney and 5-HT1A-expressing SKN-SH neuroblastoma cells, transfection of Deaf1 reduced 5-HT1A promoter activity by ~45%. To identify potential GSK3β site(s) on Deaf1, point mutations of known and predicted phosphorylation sites on Deaf1 were tested. Deaf1 repressor function was not affected by any of the mutants tested except the Y300F mutant, which augmented Deaf1 repression. Both lithium and the selective GSK3 inhibitors CHIR-99021 and AR-014418 attenuated and reversed Deaf1 repression compared to vector. This inhibition was at concentrations that maximally inhibit GSK3β activity as detected by the GSK3β-sensitive TCF/LEF reporter construct. Our results support the hypothesis that GSK3β regulates the activity of Deaf1 to repress 5-HT1A transcription and provide a potential mechanism for actions of GSK3 inhibitors on behavior.
    MeSH term(s) Humans ; Antidepressive Agents ; Glycogen Synthase Kinase 3 beta/genetics ; HEK293 Cells ; Lithium/pharmacology ; Receptor, Serotonin, 5-HT1A/genetics ; Serotonin/pharmacology
    Chemical Substances Antidepressive Agents ; Glycogen Synthase Kinase 3 beta (EC 2.7.11.1) ; Lithium (9FN79X2M3F) ; Receptor, Serotonin, 5-HT1A (112692-38-3) ; Serotonin (333DO1RDJY) ; DEAF1 protein, human ; GSK3B protein, human (EC 2.7.11.1)
    Language English
    Publishing date 2023-10-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms242115620
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article: Pédopsychiatrie en unité de soins intensifs pédiatriques.

    François, Bérengère / Gindt, Morgane / Askenazy, Florence / Fernandez, Arnaud

    Soins. Pediatrie, puericulture

    2022  Volume 43, Issue 327, Page(s) 33–35

    Abstract: A study was conducted in the pediatric intensive care and resuscitation unit of the Nice pediatric hospitals, University Hospital Center Lenval (06) from January to March 2015. Its objective was to describe the events and child psychiatric interventions ... ...

    Title translation Child psychiatry in pediatric intensive care unit.
    Abstract A study was conducted in the pediatric intensive care and resuscitation unit of the Nice pediatric hospitals, University Hospital Center Lenval (06) from January to March 2015. Its objective was to describe the events and child psychiatric interventions experienced by young patients. Of the 181 individuals managed during the research, 63 met the inclusion criteria.
    MeSH term(s) Child ; Child Psychiatry ; Hospitals, Pediatric ; Hospitals, University ; Humans ; Intensive Care Units, Pediatric
    Language French
    Publishing date 2022-06-17
    Publishing country France
    Document type Journal Article ; Review
    ZDB-ID 1234484-9
    ISSN 2214-9325 ; 1259-4792
    ISSN (online) 2214-9325
    ISSN 1259-4792
    DOI 10.1016/j.spp.2022.06.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 2788: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: New targets for new therapeutic approaches.

    François, Bruno

    Critical care (London, England)

    2014  Volume 18, Issue 6, Page(s) 669

    Abstract: Because of its resistance profiles, Pseudomonas aeruginosa remains probably one of the challenging bacteria responsible for ventilator-associated pneumonia in the ICU. Nevertheless, a much better understanding of its mechanism of virulence, such as the ... ...

    Abstract Because of its resistance profiles, Pseudomonas aeruginosa remains probably one of the challenging bacteria responsible for ventilator-associated pneumonia in the ICU. Nevertheless, a much better understanding of its mechanism of virulence, such as the type 3 secretion system that can also impact on resistance, gives some opportunities for management improvement. The most promising approach is probably the production of monoclonal antibodies that enable not only more targeted treatments but also development of some early preemptive approaches at the time of colonization through real-time diagnosis.
    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Bacterial Toxins/genetics ; Humans ; Pseudomonas Infections/drug therapy ; Pseudomonas aeruginosa/genetics
    Chemical Substances Anti-Bacterial Agents ; Bacterial Toxins
    Language English
    Publishing date 2014-12-13
    Publishing country England
    Document type Comment ; Journal Article
    ZDB-ID 2051256-9
    ISSN 1466-609X ; 1466-609X
    ISSN (online) 1466-609X
    ISSN 1466-609X
    DOI 10.1186/s13054-014-0669-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: Strengths and limitations of industry vs. academic randomized controlled trials.

    Laterre, P-F / François, B

    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases

    2015  Volume 21, Issue 10, Page(s) 906–909

    Abstract: Clinical research has evolved substantially over the last two decades, but industry-sponsored research is still substantially superior to academic research in preparing, organizing and monitoring studies. Academics have to realize that conducting ... ...

    Abstract Clinical research has evolved substantially over the last two decades, but industry-sponsored research is still substantially superior to academic research in preparing, organizing and monitoring studies. Academics have to realize that conducting clinical research has become a real job with professionalism requirements. The primary objectives of research and development clearly differ between industry and academics. In the first case, new drug development is expected to generate profit, whereas in the latter case, research is aimed at understanding mechanisms of disease, promoting evidence-based medicine, and improving public health and care. However, a large number of clinical studies do not achieve their goals, and the reasons for failure may also differ between sponsored and academic studies. Industry and academics should develop better constructive partnerships and learn from each other. Academics should guide industry in study design and in investigator site selection, and academics should benefit from industry's expertise in improving monitoring and reporting processes. Finally, the existing database from former studies should be opened and shared with academics, to enable the exploration of additional scientific questions and the generation of new hypotheses. The two types of research should not be opposed, but should take the form of a constructive collaboration, increasing the chances of reaching each individual goal.
    MeSH term(s) Biomedical Research ; Databases, Factual ; Evidence-Based Medicine ; Humans ; Industry ; Randomized Controlled Trials as Topic
    Language English
    Publishing date 2015-10
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1328418-6
    ISSN 1469-0691 ; 1470-9465 ; 1198-743X
    ISSN (online) 1469-0691
    ISSN 1470-9465 ; 1198-743X
    DOI 10.1016/j.cmi.2015.07.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 4541: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 284: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: Right ventricular failure is strongly associated with mortality in patients with moderate-to-severe COVID-19-related ARDS and appears related to respiratory worsening.

    Evrard, Bruno / Goudelin, Marine / Giraudeau, Bruno / François, Bruno / Vignon, Philippe

    Intensive care medicine

    2022  Volume 48, Issue 6, Page(s) 765–767

    MeSH term(s) COVID-19/complications ; Heart Failure ; Humans ; Respiratory Distress Syndrome/etiology ; SARS-CoV-2
    Language English
    Publishing date 2022-05-12
    Publishing country United States
    Document type Letter
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-022-06730-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1089: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: National Institute on Minority Health and Health Disparities Specialized Centers of Excellence on Minority Health and Health Disparities.

    Mujuru, Priscah / Jean-Francois, Beda / Pérez-Stable, Eliseo J

    American journal of preventive medicine

    2022  Volume 63, Issue 1 Suppl 1, Page(s) S6–S7

    MeSH term(s) Healthcare Disparities ; Humans ; Minority Groups ; Minority Health
    Language English
    Publishing date 2022-06-20
    Publishing country Netherlands
    Document type Editorial
    ZDB-ID 632646-8
    ISSN 1873-2607 ; 0749-3797
    ISSN (online) 1873-2607
    ISSN 0749-3797
    DOI 10.1016/j.amepre.2022.03.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2096: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: Experimental investigation of efficient and simple wind-turbine based on DFIG-direct power control using LCL-filter for stand-alone mode.

    Amrane, Fayssal / Francois, Bruno / Chaiba, Azeddine

    ISA transactions

    2021  Volume 125, Page(s) 631–664

    Abstract: This paper suggests an experimental implementation study of the Wind Energy Conversion System (WECS) based on efficient Direct Power Control (DPC). Stand-alone mode for variable wind speed application using Doubly-Fed Induction Generator (DFIG) is ... ...

    Abstract This paper suggests an experimental implementation study of the Wind Energy Conversion System (WECS) based on efficient Direct Power Control (DPC). Stand-alone mode for variable wind speed application using Doubly-Fed Induction Generator (DFIG) is studied and developed in this work. Due to the wind power performance limitation of traditional PI controllers, such as overshoot, response time, and static error; IP (integral-Proportional) controllers is replaced instead of the PI to control rotor current d-q components (I
    Language English
    Publishing date 2021-07-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2012746-7
    ISSN 1879-2022 ; 0019-0578
    ISSN (online) 1879-2022
    ISSN 0019-0578
    DOI 10.1016/j.isatra.2021.07.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top