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  1. Book: Modelle von Gesundheit und Krankheit

    Franke, Alexa

    (Verlag Hans Huber : Programmbereich Gesundheit)

    2012  

    Author's details Alexa Franke
    Series title Verlag Hans Huber : Programmbereich Gesundheit
    Keywords Public Health ; Disabled Persons ; Disease ; Gesundheit ; Krankheit
    Subject Erkrankung ; Krankheitszustand ; Krankheiten ; Morbus ; Nosos ; Pathos ; Gesundheitsstatus ; Gesundheitszustand
    Language German
    Size 285 S. : Ill., graph. Darst.
    Edition 3., überarb. Aufl.
    Publisher Huber
    Publishing place Bern
    Publishing country Switzerland
    Document type Book
    Note Hier auch später erschienene, unveränderte Nachdrucke
    HBZ-ID HT017358476
    ISBN 978-3-456-85120-4 ; 3-456-85120-0 ; 9783456951201 ; 9783456751207 ; 3456951205 ; 3456751206
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2012 A 3395 order for loan Magazin
    2021 A 526 available for loan (reading room) Lesesaal EG

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  2. Book ; Online: Kritische Lebensereignisse im Alter - Übergänge gestalten

    Franke, Annette / Heusinger, Josefine / Konopik, Nadine / Wolter, Birgit

    (Forschung und Praxis der Gesundheitsförderung ; Band 49)

    2017  

    Institution Bundeszentrale für Gesundheitliche Aufklärung
    Author's details Annette Franke, Josefine Heusinger, Nadine Konopik und Birgit Wolter ; Herausgeberin: Bundeszentrale für Gesundheitliche Aufklärung (BZgA)
    Series title Forschung und Praxis der Gesundheitsförderung ; Band 49
    Collection
    Subject code 610
    Language German
    Size 1 Online-Ressource (132 Seiten), Diagramme
    Edition Auflage 1.2.11.17
    Publisher Bundeszentrale für gesundheitliche Aufklärung (BZgA)
    Publishing place Köln
    Publishing country Germany
    Document type Book ; Online
    Note Open Access
    HBZ-ID HT019617586
    ISBN 9783946692386 ; 3946692389
    DOI 10.4126/FRL01-006431164
    Database Repository for Life Sciences

    Full text online

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  3. Book ; Online ; E-Book: Hirndoping & Co

    Franke, Andreas G.

    die optimierte Gesellschaft

    2019  

    Author's details Andreas G. Franke
    Language German
    Size 1 Online-Ressource (XIII, 212 Seiten), Illustrationen
    Publisher Springer
    Publishing place Berlin
    Publishing country Germany
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT020297349
    ISBN 978-3-662-58853-6 ; 9783662588529 ; 3-662-58853-6 ; 3662588528
    DOI 10.1007/978-3-662-58853-6
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

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  4. Article ; Online: Mass Spectrometry-Based Immunopeptidomics of Peptides Presented on Human Leukocyte Antigen Proteins.

    ElAbd, Hesham / Franke, Andre

    Methods in molecular biology (Clifton, N.J.)

    2024  Volume 2758, Page(s) 425–443

    Abstract: Human leukocyte antigen (HLA) proteins are a group of glycoproteins that are expressed at the cell surface, where they present peptides to T cells through physical interactions with T-cell receptors (TCRs). Hence, characterizing the set of peptides ... ...

    Abstract Human leukocyte antigen (HLA) proteins are a group of glycoproteins that are expressed at the cell surface, where they present peptides to T cells through physical interactions with T-cell receptors (TCRs). Hence, characterizing the set of peptides presented by HLA proteins, referred to hereafter as the immunopeptidome, is fundamental for neoantigen identification, immunotherapy, and vaccine development. As a result, different methods have been used over the years to identify peptides presented by HLA proteins, including competition assays, peptide microarrays, and yeast display systems. Nonetheless, over the last decade, mass spectrometry-based immunopeptidomics (MS-immunopeptidomics) has emerged as the gold-standard method for identifying peptides presented by HLA proteins. MS-immunopeptidomics enables the direct identification of the immunopeptidome in different tissues and cell types in different physiological and pathological states, for example, solid tumors or virally infected cells. Despite its advantages, it is still an experimentally and computationally challenging technique with different aspects that need to be considered before planning an MS-immunopeptidomics experiment, while conducting the experiment and with analyzing and interpreting the results. Hence, we aim in this chapter to provide an overview of this method and discuss different practical considerations at different stages starting from sample collection until data analysis. These points should aid different groups aiming at utilizing MS-immunopeptidomics, as well as, identifying future research directions to improve the method.
    MeSH term(s) Humans ; Histocompatibility Antigens Class I ; Peptides/chemistry ; HLA Antigens ; Histocompatibility Antigens Class II ; Mass Spectrometry/methods
    Chemical Substances Histocompatibility Antigens Class I ; Peptides ; HLA Antigens ; Histocompatibility Antigens Class II
    Language English
    Publishing date 2024-03-28
    Publishing country United States
    Document type Journal Article
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-0716-3646-6_23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book: Modelle von Gesundheit und Krankheit

    Franke, Alexa

    (Lehrbuch Gesundheitswissenschaften ; Verlag Hans Huber, Programmbereich Gesundheit)

    2006  

    Author's details Alexa Franke
    Series title Lehrbuch Gesundheitswissenschaften
    Verlag Hans Huber, Programmbereich Gesundheit
    Keywords Gesundheit ; Krankheit
    Subject Erkrankung ; Krankheitszustand ; Krankheiten ; Morbus ; Nosos ; Pathos ; Gesundheitsstatus ; Gesundheitszustand
    Language German
    Size 231 S. : graph. Darst.
    Edition 1. Aufl.
    Publisher Huber
    Publishing place Bern
    Publishing country Switzerland
    Document type Book
    HBZ-ID HT014774480
    ISBN 978-3-456-84353-7 ; 3-456-84353-4
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2006 A 4134 order for loan Magazin

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  6. Article: Update: Zivil-militärische Zusammenarbeit in chirurgischen Fachgesellschaften (CAMIN und EKTC)

    Güsgen, C / Franke, A

    Wehrmedizinische Monatsschrift

    2023  Volume 67, Issue 5, Page(s) 216

    Language German
    Document type Article
    ZDB-ID 506502-1
    ISSN 0043-2156
    Database Current Contents Medicine

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    In stock of ZB MED Cologne/Königswinter

    Un I Zs.516: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  7. Book ; Thesis: Die Rolle von BMP-4 in der Entwicklung chromaffiner Zellen

    Franke, Aylin

    2005  

    Author's details vorgelegt von Aylin Franke
    Language German
    Size III, 82 Bl. : Ill., graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Heidelberg, Univ., Diss., 2005
    HBZ-ID HT014964881
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2007 E 473 order for loan Magazin

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  8. Book: Das HEDE-Training ®

    Franke, Alexa / Witte, Maibritt

    Manual zur Gesundheitsförderung auf Basis der Salutogenese

    (Prävention und Gesundheitsförderung)

    2009  

    Author's details Alexa Franke ; Maibritt Witte
    Series title Prävention und Gesundheitsförderung
    Keywords Salutogenese ; Kohärenz ; Psychotraining
    Subject Mentales Training ; Psychologisches Training
    Language German
    Size 112 S. : Ill., graph. Darst.
    Edition 1. Aufl.
    Publisher Huber
    Publishing place Bern
    Publishing country Switzerland
    Document type Book
    Accompanying material 1 CD-ROM (12 cm)
    HBZ-ID HT016057162
    ISBN 978-3-456-84774-0 ; 3-456-84774-2
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2010 A 1098 order for loan Magazin
    2010 MO 120 <<[Begleitmaterial]>> order for loan Magazin

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  9. Article ; Online: AI revolution in healthcare and medicine and the (re-)emergence of inequalities and disadvantages for ageing population.

    Stypińska, Justyna / Franke, Annette

    Frontiers in sociology

    2023  Volume 7, Page(s) 1038854

    Abstract: AI systems in medicine and healthcare are being extensively explored in prevention, diagnosis, novel drug designs and after-care. The application of AI technology in healthcare systems promises impressive outcomes such as equalising healthcare, reducing ... ...

    Abstract AI systems in medicine and healthcare are being extensively explored in prevention, diagnosis, novel drug designs and after-care. The application of AI technology in healthcare systems promises impressive outcomes such as equalising healthcare, reducing mortality rate and human error, reducing medical costs, as well as reducing reliance on social services. In the light of the WHO "Decade of Healthy Ageing", AI applications are designed as digital innovations to support the quality of life for older persons. However, the emergence of evidence of different types of algorithmic bias in AI applications, ageism in the use of digital devices and platforms, as well as age bias in digital data suggests that the use of AI might have discriminatory effects on older population or even cause harm. This paper addresses the issue of age biases and age discrimination in AI applications in medicine and healthcare systems and try to identify main challenges in this area. It will reflect on the potential of AI applications to amplify the already existing health inequalities by discussing two levels where potential negative impact of AI on age inequalities might be observed. Firstly, we will address the technical level of age bias in algorithms and digital datasets (especially health data). Secondly, we will discuss the potential disparate outcomes of automatic decision-making systems (ADMs) used in healthcare on the older population. These examples will demonstrate, although only partially, how AI systems may create new structures of age inequalities and novel dimensions of exclusion in healthcare and medicine.
    Language English
    Publishing date 2023-01-23
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2297-7775
    ISSN (online) 2297-7775
    DOI 10.3389/fsoc.2022.1038854
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Assessing the impact of climate change on crop production in southern Africa: a review

    Franke, AC

    South African journal of plant and soil =. 2021 Jan. 01, v. 38, no. 1

    2021  

    Abstract: This paper provides a systematic review of studies assessing the impact of climate change on crop yields in southern Africa. Moreover, it synthesises the current knowledge of the impact of elevated ambient CO₂ levels (eCO₂) and temperatures on ... ...

    Abstract This paper provides a systematic review of studies assessing the impact of climate change on crop yields in southern Africa. Moreover, it synthesises the current knowledge of the impact of elevated ambient CO₂ levels (eCO₂) and temperatures on physiological processes, and the application of this knowledge in mechanistic crop models. While eCO₂ evidently has a strong impact on photosynthesis and crop water use, it is uncertain how this will work out for the climatic and crop management conditions prevailing in southern Africa. The impact of heat stress on crop reproductive processes and the process of transpiration cooling mitigating heat stress are poorly represented in models, while both process are relevant given the climatic conditions prevailing in southern Africa. Twenty studies assessing the impact of climate change on future yields of crops, mostly maize, have been retrieved. The results suggest that potato, Bambara groundnut and sugarcane yields may improve. No consistent trends for maize and sorghum could be identified. While yield predictions are obviously context-specific, large uncertainties related to climate predictions and crop models imply results should be treated with caution. Suggestions are made for field experimentation and the improved application of crop models for climate change research in the region.
    Keywords Vigna subterranea ; carbon dioxide ; climate change ; corn ; crop management ; field experimentation ; heat stress ; photosynthesis ; potatoes ; soil ; sugarcane ; systematic review ; transpiration ; Southern Africa
    Language English
    Dates of publication 2021-0101
    Size p. 1-12.
    Publishing place Taylor & Francis
    Document type Article
    Note NAL-AP-2-clean
    ZDB-ID 2672837-0
    ISSN 2167-034X ; 0257-1862
    ISSN (online) 2167-034X
    ISSN 0257-1862
    DOI 10.1080/02571862.2020.1844325
    Database NAL-Catalogue (AGRICOLA)

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