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  1. Book ; Online ; E-Book: On life

    Harold, Franklin M.

    cells, genes, and the evolution of complexity

    (Oxford scholarship online)

    2022  

    Abstract: Offering an inside look into the world around us, microbiologist Franklin M. Harold makes life ...

    Author's details Franklin M. Harold
    Series title Oxford scholarship online
    Abstract Offering an inside look into the world around us, microbiologist Franklin M. Harold makes life intelligible for readers interested in biology. The book traces living things and how they operate, focusing on questions about the interaction between physics, chemistry, and biology.
    Keywords Biology ; Cytology ; Life (Biology)
    Subject code 570
    Language English
    Size 1 online resource (225 pages)
    Publisher Oxford University Press
    Publishing place New York, New York
    Document type Book ; Online ; E-Book
    Note Also issued in print: 2022.
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 0-19-760457-9 ; 0-19-760456-0 ; 0-19-760454-4 ; 978-0-19-760457-1 ; 978-0-19-760456-4 ; 978-0-19-760454-0
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article: Radiotherapy in Some Malignant Conditions of the Mouth.

    Franklin, Milton

    International dental journal (Philadelphia, Pa.)

    2023  Volume 25, Issue 12, Page(s) 905–910

    Language English
    Publishing date 2023-11-01
    Publishing country United States
    Document type Journal Article
    ISSN 1069-0441
    ISSN 1069-0441
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Animals as Beneficiaries of Biomedical Research Originally Intended for Humans.

    Loew, Franklin M

    ILAR journal

    2022  Volume 62, Issue 3, Page(s) 367–368

    MeSH term(s) Humans ; Animals ; United States ; Biomedical Research
    Language English
    Publishing date 2022-11-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 2192062-X
    ISSN 1930-6180 ; 1084-2020
    ISSN (online) 1930-6180
    ISSN 1084-2020
    DOI 10.1093/ilar/ilac014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Whither Decision-Analytic Modelling-Based Economic Evaluation for Health Care Decision Making?

    Hunter, Rachael Maree / Franklin, Matthew

    PharmacoEconomics - open

    2024  

    Language English
    Publishing date 2024-04-25
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2874287-4
    ISSN 2509-4254 ; 2509-4262
    ISSN (online) 2509-4254
    ISSN 2509-4262
    DOI 10.1007/s41669-024-00492-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: ICER report on Alzheimer's disease: implications from a patient perspective.

    Franklin, Meg

    Journal of managed care & specialty pharmacy

    2021  Volume 27, Issue 11, Page(s) 1618–1620

    Abstract: DISCLOSURES: ...

    Abstract DISCLOSURES:
    MeSH term(s) Academies and Institutes ; Advisory Committees ; Alzheimer Disease ; Antibodies, Monoclonal, Humanized/therapeutic use ; Health Services Accessibility ; Health Status Disparities ; Humans ; Patient Participation
    Chemical Substances Antibodies, Monoclonal, Humanized ; aducanumab (105J35OE21)
    Language English
    Publishing date 2021-10-12
    Publishing country United States
    Document type Journal Article
    ISSN 2376-1032
    ISSN (online) 2376-1032
    DOI 10.18553/jmcp.2021.27.11.1618
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Enabling QALY estimation in mental health trials and care settings: mapping from the PHQ-9 and GAD-7 to the ReQoL-UI or EQ-5D-5L using mixture models.

    Franklin, Matthew / Hernández Alava, Monica

    Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

    2023  Volume 32, Issue 10, Page(s) 2763–2778

    Abstract: Purpose: Patient-reported outcome measures (PROMs) are commonly collected in trials and some care settings, but preference-based PROMs required for economic evaluation are often missing. For these situations, mapping models are needed to predict ... ...

    Abstract Purpose: Patient-reported outcome measures (PROMs) are commonly collected in trials and some care settings, but preference-based PROMs required for economic evaluation are often missing. For these situations, mapping models are needed to predict preference-based (aka utility) scores. Our objective is to develop a series of mapping models to predict preference-based scores from two mental health PROMs: Patient Health Questionnaire-9 (PHQ-9; depression) and Generalised Anxiety Questionnaire-7 (GAD-7; anxiety). We focus on preference-based scores for the more physical-health-focussed EQ-5D (five-level England and US value set, and three-level UK cross-walk) and more mental-health-focussed Recovering Quality-of-Life Utility Index (ReQoL-UI).
    Methods: We used trial data from the Improving Access to Psychological Therapies (IAPT) mental health services (now called NHS Talking Therapies), England, with a focus on people with depression and/or anxiety caseness. We estimated adjusted limited dependent variable or beta mixture models (ALDVMMs or Betamix, respectively) using GAD-7, PHQ-9, age, and sex as covariates. We followed ISPOR mapping guidance, including assessing model fit using statistical and graphical techniques.
    Results: Over six data collection time-points between baseline and 12-months, 1340 observed values (N ≤ 353) were available for analysis. The best fitting ALDVMMs had 4-components with covariates of PHQ-9, GAD-7, sex, and age; age was not a probability variable for the final ReQoL-UI mapping model. Betamix had practical benefits over ALDVMMs only when mapping to the US value set.
    Conclusion: Our mapping functions can predict EQ-5D-5L or ReQoL-UI related utility scores for QALY estimation as a function of variables routinely collected within mental health services or trials, such as the PHQ-9 and/or GAD-7.
    MeSH term(s) Humans ; Mental Health ; Patient Health Questionnaire ; Quality of Life/psychology ; Surveys and Questionnaires
    Chemical Substances betamix (8074-50-8)
    Language English
    Publishing date 2023-06-14
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1161148-0
    ISSN 1573-2649 ; 0962-9343
    ISSN (online) 1573-2649
    ISSN 0962-9343
    DOI 10.1007/s11136-023-03443-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3796: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Workforce perspective on racial and ethnic equity in early childhood autism evaluation and treatment: "The cornerstone of everything we do".

    Buck, A / Hurewitz, S / Franklin, M Scotton

    Autism : the international journal of research and practice

    2024  , Page(s) 13623613241235522

    Abstract: Lay abstract: Black and non-White Latinx children tend to receive autism diagnoses later in life and with a higher degree of impairment than White children. The purpose of this study was to learn what is currently helping as well as preventing Black and ...

    Abstract Lay abstract: Black and non-White Latinx children tend to receive autism diagnoses later in life and with a higher degree of impairment than White children. The purpose of this study was to learn what is currently helping as well as preventing Black and non-White Latinx children from getting access to autism evaluation and services. We held virtual interviews with 26 experts who work with autistic children and their families, including clinical providers, researchers, advocates, and policymakers/government representatives. From these interviews, we identified four themes that have an impact on equity in autism services: (1)
    Language English
    Publishing date 2024-03-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 1338513-6
    ISSN 1461-7005 ; 1362-3613
    ISSN (online) 1461-7005
    ISSN 1362-3613
    DOI 10.1177/13623613241235522
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5838: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Mapping functions for the PHQ-9 and GAD-7 to generate EQ-5D-3L for economic evaluation.

    Mukuria, Clara / Franklin, Matthew / Hinde, Sebastian

    The European journal of health economics : HEPAC : health economics in prevention and care

    2024  

    Abstract: Purpose: Generic preferenced-based measures, such as EQ-5D-3L, that are used to estimate quality adjusted life years (QALYs) for economic evaluation are not always available in clinical trials. Predicting EQ-5D-3L values from the commonly used Patient ... ...

    Abstract Purpose: Generic preferenced-based measures, such as EQ-5D-3L, that are used to estimate quality adjusted life years (QALYs) for economic evaluation are not always available in clinical trials. Predicting EQ-5D-3L values from the commonly used Patient Health Questionnaire 9 (PHQ-9) and Generalised Anxiety Disorder-7 (GAD-7) would allow estimation of QALYs from such trials. The aim was to provide mapping functions to estimate EQ-5D-3L from PHQ-9 and GAD-7 to facilitate economic evaluation.
    Methods: Data was drawn from four trials of patients with symptoms of depression testing collaborative care or computerised cognitive behavioural therapy. Patients completed PHQ-9, GAD-7, and EQ-5D-3L at different timepoints. Mapping was undertaken using adjusted limited dependent variable mixture models (ALDVMM), ordinary least squares (OLS), and Tobit models based on PHQ-9, GAD-7 scores or questions, and age to predict EQ-5D-3L utilities. Models were selected based on mean error (ME), mean absolute error (MAE), root mean squared error (RMSE), model goodness of fit, and visual inspection of the predictions.
    Results: There were 5583 and 3942 observations for EQ-5D-3L combined with PHQ-9 and GAD-7 respectively. ALDVMM models had low ME ( ≤|0.0018|) and MAE ranging from 0.189 to 0.192, while RMSE was from 0.251 to 0.254 and had better predictions than OLS and Tobit models. ALDVMM models with four components based on PHQ-9 and GAD-7 scores are recommended for estimating EQ-5D-3L utilities.
    Conclusions: Recommended mapping functions provide users with an approach to estimate EQ-5D-3L utilities for economic evaluation using PHQ-9, GAD-7, or both scores where they have been used together.
    Language English
    Publishing date 2024-04-25
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2045253-6
    ISSN 1618-7601 ; 1618-7598
    ISSN (online) 1618-7601
    ISSN 1618-7598
    DOI 10.1007/s10198-024-01692-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5475: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Spatial Variation in Humidity and the Onset of Seasonal Influenza Across the Contiguous United States.

    Serman, E / Thrastarson, H Th / Franklin, M / Teixeira, J

    GeoHealth

    2022  Volume 6, Issue 2, Page(s) e2021GH000469

    Abstract: In recent years, environmental factors, particularly humidity, have been used to inform influenza prediction models. This study aims to quantify the relationship between humidity and influenza incidence at the state-level in the contiguous United States. ...

    Abstract In recent years, environmental factors, particularly humidity, have been used to inform influenza prediction models. This study aims to quantify the relationship between humidity and influenza incidence at the state-level in the contiguous United States. Piecewise segmented regressions were performed on specific humidity data from NASA's Atmospheric Infrared Sounder (AIRS) and incident influenza estimates from Google Flu Trends to identify threshold values of humidity that signal the onset of an influenza outbreak. Our results suggest that influenza incidence increases after reaching a humidity threshold that is state-specific. A linear regression showed that the state-specific thresholds were associated with annual average humidity conditions (
    Language English
    Publishing date 2022-02-01
    Publishing country United States
    Document type Journal Article
    ISSN 2471-1403
    ISSN (online) 2471-1403
    DOI 10.1029/2021GH000469
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: An atypical facial eruption in skin of color: A rare presentation of histiocytoid Sweet syndrome.

    Ehlert, Brittany / Shegos, Lauren / Franklin, Matthew / Buckley, Kaila / Rodger, Jaimie

    JAAD case reports

    2024  Volume 47, Page(s) 6–9

    Language English
    Publishing date 2024-03-09
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2834220-3
    ISSN 2352-5126
    ISSN 2352-5126
    DOI 10.1016/j.jdcr.2024.02.027
    Database MEDical Literature Analysis and Retrieval System OnLINE

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