LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 360

Search options

  1. Article ; Online: African Swine Fever Virus Infection and Cytokine Response In Vivo: An Update.

    Franzoni, Giulia / Pedrera, Miriam / Sánchez-Cordón, Pedro J

    Viruses

    2023  Volume 15, Issue 1

    Abstract: African swine fever (ASF) is a hemorrhagic viral disease of domestic pigs and wild suids ( ... ...

    Abstract African swine fever (ASF) is a hemorrhagic viral disease of domestic pigs and wild suids (all
    MeSH term(s) Swine ; Animals ; African Swine Fever ; African Swine Fever Virus ; Cytokines/metabolism ; Interleukin-6/metabolism ; Interleukin-1/metabolism ; Sus scrofa
    Chemical Substances Cytokines ; Interleukin-6 ; Interleukin-1
    Language English
    Publishing date 2023-01-14
    Publishing country Switzerland
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v15010233
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article: The Cell-Mediated Immune Response against

    Righi, Cecilia / Franzoni, Giulia / Feliziani, Francesco / Jones, Clinton / Petrini, Stefano

    Vaccines

    2023  Volume 11, Issue 4

    Abstract: Bovine Alphaherpesvirus ... ...

    Abstract Bovine Alphaherpesvirus 1
    Language English
    Publishing date 2023-04-02
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2703319-3
    ISSN 2076-393X
    ISSN 2076-393X
    DOI 10.3390/vaccines11040785
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article: Cell Lines for the Development of African Swine Fever Virus Vaccine Candidates: An Update.

    Meloni, Dionigia / Franzoni, Giulia / Oggiano, Annalisa

    Vaccines

    2022  Volume 10, Issue 5

    Abstract: African swine fever virus (ASFV) is the etiological agent of a highly lethal disease in both domestic and wild pigs. The virus has rapidly spread worldwide and has no available licensed vaccine. An obstacle to the construction of a safe and efficient ... ...

    Abstract African swine fever virus (ASFV) is the etiological agent of a highly lethal disease in both domestic and wild pigs. The virus has rapidly spread worldwide and has no available licensed vaccine. An obstacle to the construction of a safe and efficient vaccine is the lack of a suitable cell line for ASFV isolation and propagation. Macrophages are the main targets for ASFV, and they have been widely used to study virus-host interactions; nevertheless, obtaining these cells is time-consuming and expensive, and they are not ethically suitable for the production of large-scale vaccines. To overcome these issues, different virulent field isolates have been adapted on monkey or human continuous cells lines; however, several culture passages often lead to significant genetic modifications and the loss of immunogenicity of the adapted strain. Thus, several groups have attempted to establish a porcine cell line able to sustain ASFV growth. Preliminary data suggested that some porcine continuous cell lines might be an alternative to primary macrophages for ASFV research and for large-scale vaccine production, although further studies are still needed. In this review, we summarize the research to investigate the most suitable cell line for ASFV isolation and propagation.
    Language English
    Publishing date 2022-04-29
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2703319-3
    ISSN 2076-393X
    ISSN 2076-393X
    DOI 10.3390/vaccines10050707
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Book ; Online: Interaction of monocytes and derived macrophage subsets with African swine fever viruses of diverse virulence

    Franzoni, Giulia

    2017  

    Author's details Giulia Franzoni
    Language English
    Size Online-Ressource
    Publishing place Sassari
    Document type Book ; Online
    Database Special collection on veterinary medicine and general parasitology

    More links

    Kategorien

  5. Article: Effect of glutamic acid foliar applications on lettuce under water stress.

    Franzoni, Giulia / Cocetta, Giacomo / Ferrante, Antonio

    Physiology and molecular biology of plants : an international journal of functional plant biology

    2021  Volume 27, Issue 5, Page(s) 1059–1072

    Abstract: The yield and quality of leafy vegetables can be compromised by reduced water availability. Glutamic acid is involved in different biological processes and among them it plays an important role in chlorophyll and proline biosynthesis. The aim of this ... ...

    Abstract The yield and quality of leafy vegetables can be compromised by reduced water availability. Glutamic acid is involved in different biological processes and among them it plays an important role in chlorophyll and proline biosynthesis. The aim of this work was to evaluate the possible efficacy of glutamic acid in counteracting water stress in romaine lettuce. Lettuce plants were grown in pots filled with substrate and subjected to water deprivation. A glutamic acid solution (1.9 mM) was applied as foliar treatment, both in stressed and non-stressed plants. The effect of the treatment was evaluated at different time points during the experiment in order to evaluate changes at a molecular, physiological, biochemical and agronomic level. Yield was reduced by 35% in stressed plants, while no significant changes in quality parameters were observed, except for nitrate content, which increased under water stress. At a molecular level, the expression of genes encoding for ROS scavenging enzymes was monitored but, apparently, glutamic acid did not significantly prevent the water stress response. Slightly positive effects deriving from glutamic acid application were found for nitrate and proline contents, suggesting that a possible mode of action of glutamic acid would involve a role for these molecules. Further studies are required, also on other crop species, for confirming these results. Different concentrations and application modes should be also tested.
    Language English
    Publishing date 2021-04-22
    Publishing country India
    Document type Journal Article
    ZDB-ID 2487126-6
    ISSN 0974-0430 ; 0971-5894
    ISSN (online) 0974-0430
    ISSN 0971-5894
    DOI 10.1007/s12298-021-00984-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: Biochemical and molecular changes in peach fruit exposed to cold stress conditions.

    Franzoni, Giulia / Spadafora, Natasha Damiana / Sirangelo, Tiziana Maria / Ferrante, Antonio / Rogers, Hilary J

    Molecular horticulture

    2023  Volume 3, Issue 1, Page(s) 24

    Abstract: Storage or transportation temperature is very important for preserving the quality of fruit. However, low temperature in sensitive fruit such as peach can induce loss of quality. Fruit exposed to a specific range of temperatures and for a longer period ... ...

    Abstract Storage or transportation temperature is very important for preserving the quality of fruit. However, low temperature in sensitive fruit such as peach can induce loss of quality. Fruit exposed to a specific range of temperatures and for a longer period can show chilling injury (CI) symptoms. The susceptibility to CI at low temperature varies among cultivars and genetic backgrounds. Along with agronomic management, appropriate postharvest management can limit quality losses. The importance of correct temperature management during postharvest handling has been widely demonstrated. Nowadays, due to long-distance markets and complex logistics that require multiple actors, the management of storage/transportation conditions is crucial for the quality of products reaching the consumer.Peach fruit exposed to low temperatures activate a suite of physiological, metabolomic, and molecular changes that attempt to counteract the negative effects of chilling stress. In this review an overview of the factors involved, and plant responses is presented and critically discussed. Physiological disorders associated with CI generally only appear after the storage/transportation, hence early detection methods are needed to monitor quality and detect internal changes which will lead to CI development. CI detection tools are assessed: they need to be easy to use, and preferably non-destructive to avoid loss of products.
    Language English
    Publishing date 2023-11-13
    Publishing country England
    Document type Journal Article ; Review
    ISSN 2730-9401
    ISSN (online) 2730-9401
    DOI 10.1186/s43897-023-00073-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article: Effect of glutamic acid foliar applications on lettuce under water stress

    Franzoni, Giulia / Cocetta, Giacomo / Ferrante, Antonio

    Physiology and molecular biology of plants. 2021 May, v. 27, no. 5

    2021  

    Abstract: The yield and quality of leafy vegetables can be compromised by reduced water availability. Glutamic acid is involved in different biological processes and among them it plays an important role in chlorophyll and proline biosynthesis. The aim of this ... ...

    Abstract The yield and quality of leafy vegetables can be compromised by reduced water availability. Glutamic acid is involved in different biological processes and among them it plays an important role in chlorophyll and proline biosynthesis. The aim of this work was to evaluate the possible efficacy of glutamic acid in counteracting water stress in romaine lettuce. Lettuce plants were grown in pots filled with substrate and subjected to water deprivation. A glutamic acid solution (1.9 mM) was applied as foliar treatment, both in stressed and non-stressed plants. The effect of the treatment was evaluated at different time points during the experiment in order to evaluate changes at a molecular, physiological, biochemical and agronomic level. Yield was reduced by 35% in stressed plants, while no significant changes in quality parameters were observed, except for nitrate content, which increased under water stress. At a molecular level, the expression of genes encoding for ROS scavenging enzymes was monitored but, apparently, glutamic acid did not significantly prevent the water stress response. Slightly positive effects deriving from glutamic acid application were found for nitrate and proline contents, suggesting that a possible mode of action of glutamic acid would involve a role for these molecules. Further studies are required, also on other crop species, for confirming these results. Different concentrations and application modes should be also tested.
    Keywords biosynthesis ; chlorophyll ; crops ; glutamic acid ; mechanism of action ; molecular biology ; nitrates ; proline ; romaine lettuce ; stress response ; water deprivation
    Language English
    Dates of publication 2021-05
    Size p. 1059-1072.
    Publishing place Springer India
    Document type Article
    Note NAL-AP-2-clean
    ZDB-ID 2487126-6
    ISSN 0974-0430 ; 0971-5894
    ISSN (online) 0974-0430
    ISSN 0971-5894
    DOI 10.1007/s12298-021-00984-6
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

  8. Article: Maceration Time Affects the Efficacy of Borage Extracts as Potential Biostimulant on Rocket Salad

    Franzoni, Giulia / Bulgari, Roberta / Ferrante, Antonio

    Agronomy. 2021 Oct. 28, v. 11, no. 11

    2021  

    Abstract: The efficacy of plant-based biostimulants lays on the extraction of bioactive compounds that can trigger positive biological responses in plants. Their use has been increasing for lowering the production costs, enhance the yield and the stress tolerance, ...

    Abstract The efficacy of plant-based biostimulants lays on the extraction of bioactive compounds that can trigger positive biological responses in plants. Their use has been increasing for lowering the production costs, enhance the yield and the stress tolerance, and improve the cropping systems’ sustainability. The aim of this work was to investigate the effect of maceration time on borage extracts, subsequently sprayed on rocket plants hydroponically grown. A preliminary test was also assessed to evaluate the extracts’ effect on seeds germination. Borage leaves and flowers were separated and macerated in the same conditions for different times. The obtained borage extracts were applied two times during the cultivation of rocket plants. The yield was not affected by the treatments, while the quality of leafy vegetables was improved. The results indicated that the flower extracts (FE) were more active than leaf extracts (LE) in stimulating the crop response. Promising results were observed on the nitrate assimilation, with reduced accumulation in the edible and commercial parts. Non-destructive analysis revealed that electron transport rates were significantly higher in treated plants. Biostimulant effects were also confirmed by the lowering of sucrose and sugars content in the treated plants and by a general increment of secondary metabolites.
    Keywords Eruca vesicaria subsp. sativa ; agronomy ; electron transfer ; flowers ; germination ; hydroponics ; leaves ; maceration ; nitrates ; nondestructive methods ; secondary metabolites ; stress tolerance ; sucrose
    Language English
    Dates of publication 2021-1028
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    ZDB-ID 2607043-1
    ISSN 2073-4395
    ISSN 2073-4395
    DOI 10.3390/agronomy11112182
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

  9. Article: Biostimulants on Crops: Their Impact under Abiotic Stress Conditions

    Franzoni, Giulia / Cocetta, Giacomo / Prinsi, Bhakti / Ferrante, Antonio / Espen, Luca

    Horticulturae. 2022 Feb. 22, v. 8, no. 3

    2022  

    Abstract: Biostimulants are agronomic tools that have been gaining importance in the reduction of fertilizer applications. They can improve the yield of cropping systems or preventing crop yield losses under abiotic stresses. Biostimulants can be composed of ... ...

    Abstract Biostimulants are agronomic tools that have been gaining importance in the reduction of fertilizer applications. They can improve the yield of cropping systems or preventing crop yield losses under abiotic stresses. Biostimulants can be composed of organic and inorganic materials and most of the components are still unknown. The characterization of the molecular mechanism of action of biostimulants can be obtained using the omics approach, which includes the determination of transcriptomic, proteomic, and metabolomic changes in treated plants. This review reports an overview of the biostimulants, taking stock on the recent molecular studies that are contributing to clarify their action mechanisms. The omics studies can provide an overall evaluation of a crop’s response, connecting the molecular changes with the physiological pathways activated and the performance with or without stress conditions. The multiple responses of plants treated with biostimulants must be correlated with the phenotype changes. In this context, it is also crucial to design an adequate experimental plan and statistical data analysis, in order to find robust correlations between biostimulant treatments and crop performance.
    Keywords abiotic stress ; crop yield ; experimental design ; fertilizers ; mechanism of action ; metabolomics ; phenotype ; proteomics ; transcriptomics
    Language English
    Dates of publication 2022-0222
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    ZDB-ID 2813983-5
    ISSN 2311-7524
    ISSN 2311-7524
    DOI 10.3390/horticulturae8030189
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

  10. Article: Effect of exogenous application of salt stress and glutamic acid on lettuce (Lactuca sativa L.)

    Franzoni, Giulia / Cocetta, Giacomo / Trivellini, Alice / Garabello, Christian / Contartese, Valeria / Ferrante, Antonio

    Scientia horticulturae. 2022 June 01, v. 299

    2022  

    Abstract: Salinity is a serious environmental issue which can negatively affect crop growth and productivity worldwide. Lettuce is generally considered as a salt-sensitive crop; however, different cultivars may have different adaptive mechanisms to this ... ...

    Abstract Salinity is a serious environmental issue which can negatively affect crop growth and productivity worldwide. Lettuce is generally considered as a salt-sensitive crop; however, different cultivars may have different adaptive mechanisms to this environmental stress. The application of biostimulants has proven to be a strategic strategy to improve plant responses to abiotic stresses and to foster resilience of crops during cultivation. This study intended to explore the physiological mechanisms underlying Romaine lettuce plant responses to salt stress, also in combination with the exogenous application of glutamic acid. The glutamic acid treatment was applied as foliar spray for the first time before salt exposure, followed by three applications during the stress. To understand the effect of salinity and glutamic acid treatment, different physiological and molecular analytical determinations were performed. High salinity induced a general stimulation of PSII and chlorophyll content. In particular, the performance index (+102%) and the number of reaction centres per cross section (+75,7%) increased, whereas the energy dissipation as heat per reaction centres (-32,1%) and the net rate of the centres’ closure (Mo) (-39.4%) decreased. Moreover, a reduction of yield (-26,5%) was observed in plants grown under high salinity. The concentration of proline was stimulated by salinity whereas ABA levels were reduced. The analyses of the genes encoding for ROS scavenging enzymes showed a general downregulation in response to salinity with the only exception of LsSOD. The application of the glutamic acid did not show a clear effect of the amino acid on lettuce plants, regardless the different growing conditions.
    Keywords Lactuca sativa ; acid treatment ; chlorophyll ; cultivars ; energy ; foliar spraying ; glutamic acid ; heat ; photosystem II ; proline ; romaine lettuce ; salinity ; salt stress
    Language English
    Dates of publication 2022-0601
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 185557-8
    ISSN 0304-4238
    ISSN 0304-4238
    DOI 10.1016/j.scienta.2022.111027
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

To top