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  1. Book: Synopsis of diseases of the chest

    Fraser, Richard S.

    2005  

    Title variant Diseases of the chest
    Author's details Richard S. Fraser
    Keywords Thoracic Diseases ; Lung Diseases ; Brustkorbkrankheit
    Subject Brustkorb ; Thoraxkrankheit
    Language English
    Size XI, 12 [Bl.], 957 S. : zahlr. Ill.
    Edition 3. ed.
    Publisher Elsevier
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT014117622
    ISBN 0-7216-0445-5 ; 978-0-7216-0445-9
    Database Catalogue ZB MED Medicine, Health

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  2. Book: What's law got to do with it?

    Fraser, Richard C.

    Health care reform in Canada ; a Law for the Future Fund Project

    1994  

    Institution Canadian Bar Association / Task Force on Health Care
    Author's details The Canadian Bar Association, Task Force on Health Care. [Health Care Task Force members: Richard C. Fraser, Chair]
    Keywords Health Care Reform / Canada ; Health Services Accessibility / Canada ; Health Care Costs / Canada / legislation
    Language English
    Size V, 118 S.
    Publishing place Ottawa, Ontario
    Publishing country Canada
    Document type Book
    HBZ-ID HT007376588
    ISBN 0-920742-32-7 ; 978-0-920742-32-7
    Database Catalogue ZB MED Medicine, Health

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  3. Book: Synopsis of diseases of the chest

    Fraser, Richard S.

    1993  

    Title variant Diseases of the chest
    Author's details Richard S. Fraser
    Keywords Thoracic Diseases ; Brustkorbkrankheit
    Subject Brustkorb ; Thoraxkrankheit
    Language English
    Size XII, 1020 S. : Ill.
    Edition 2. ed., 1. print.
    Publisher Saunders
    Publishing place Philadelphia u.a.
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT006298748
    ISBN 0-7216-3669-1 ; 978-0-7216-3669-6
    Database Catalogue ZB MED Medicine, Health

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  4. Article ; Online: Venous air embolism: artefactual air entrapment and autopsy technique.

    Zolotarov, Pylyp / Fraser, Richard

    International journal of legal medicine

    2019  Volume 134, Issue 3, Page(s) 1033–1036

    Abstract: Venous air embolism (VAE) is a rare cause of death for which special procedures are needed for autopsy diagnosis. The current one of choice was devised by Richter in 1905 to prevent introduction of gas into the right heart while opening the thorax. We ... ...

    Abstract Venous air embolism (VAE) is a rare cause of death for which special procedures are needed for autopsy diagnosis. The current one of choice was devised by Richter in 1905 to prevent introduction of gas into the right heart while opening the thorax. We could find no published data demonstrating that that this occurs during standard autopsy technique. Two scenarios were investigated. In the first, the study group included cases using the traditional method to open the thoracic cage; in the control group, Richter's method was used. Gas was collected under water and measured in a calibrated tube. The second scenario involved cases in which an intracardiac catheter was present at autopsy. In these, 50 mL of air was injected prior to chest opening and the amount of intracardiac air was measured. The first (non-injected) study and control groups consisted of 28 and 26 cases, respectively. Gas was identified in 3 cases (10%) in the study group and 2 cases (7%) in the control group. In the ten injected cases, there was a significant difference in the amount of the gas recovered (10 mL in the standard cases and 30 mL in the Richter group). No significant artifactual gas entrapment occurs in the right heart using the standard autopsy technique. However, it is possible that this technique may cause loss of intracardiac gas and if there is a clinical suspicion of VAE, Richter's technique should be used.
    MeSH term(s) Autopsy/methods ; Case-Control Studies ; Embolism, Air/diagnosis ; Gases/analysis ; Humans
    Chemical Substances Gases
    Language English
    Publishing date 2019-10-08
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1055109-8
    ISSN 1437-1596 ; 0937-9827
    ISSN (online) 1437-1596
    ISSN 0937-9827
    DOI 10.1007/s00414-019-02158-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Narratives of the museum specimen: a pilot project.

    Totten, Stephanie / Fraser, Richard

    Medical education

    2018  Volume 52, Issue 11, Page(s) 1186

    MeSH term(s) Adult ; Biological Specimen Banks ; Education, Medical, Undergraduate/methods ; Female ; Humans ; Male ; Museums ; Pilot Projects ; Specimen Handling ; Students, Medical/psychology ; Young Adult
    Language English
    Publishing date 2018-10-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 195274-2
    ISSN 1365-2923 ; 0308-0110
    ISSN (online) 1365-2923
    ISSN 0308-0110
    DOI 10.1111/medu.13725
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Superiority of systemic bleomycin to intradermal HOCl for the study of interstitial lung disease.

    Morozan, Arina / Joy, Sydney / Fujii, Utako / Fraser, Richard / Watters, Kevin / Martin, James G / Colmegna, Inés

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 20577

    Abstract: Systemic sclerosis (SSc) is an autoimmune disease characterized by vasculopathy, immune dysregulation, and multi-organ fibrosis. Interstitial lung disease (ILD) is a complication of SSc and a leading cause of SSc-death. The administration of hypochlorous ...

    Abstract Systemic sclerosis (SSc) is an autoimmune disease characterized by vasculopathy, immune dysregulation, and multi-organ fibrosis. Interstitial lung disease (ILD) is a complication of SSc and a leading cause of SSc-death. The administration of hypochlorous acid (HOCl) intradermally in the mouse (HOCl-SSc) purportedly shows several features typical of SSc. We studied the model by injecting BALB/c mice daily intradermally with HOCl for 6-weeks, an exposure reported to induce lung fibrosis. On day 42, the skinfold thickness and the dermal thickness were two and three times larger respectively in the HOCl group compared to controls. HOCl treatment did not result in histological features of pulmonary fibrosis nor significant changes in lung compliance. Automated image analysis of HOCl mice lungs stained with picrosirius red did not show increased collagen deposition. HOCl injections did not increase pulmonary mRNA expression of pro-fibrotic genes nor induced the production of serum advanced oxidation protein products and anti-topoisomerase 1 antibodies. Immune cells in bronchoalveolar lavage fluid (BALF) and whole lung digests were not increased in HOCl-treated animals. Since lung fibrosis is proposed to be triggered by oxidative stress, we injected HOCl to Nrf2
    MeSH term(s) Animals ; Mice ; Pulmonary Fibrosis/metabolism ; Hypochlorous Acid/metabolism ; Bleomycin/adverse effects ; Bleomycin/metabolism ; NF-E2-Related Factor 2/metabolism ; Skin/metabolism ; Fibrosis ; Lung Diseases, Interstitial/pathology ; Scleroderma, Systemic/pathology ; Lung/pathology ; Disease Models, Animal
    Chemical Substances Hypochlorous Acid (712K4CDC10) ; Bleomycin (11056-06-7) ; NF-E2-Related Factor 2
    Language English
    Publishing date 2023-11-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-47083-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Intracellular

    Malet, Karim / Faure, Emmanuel / Adam, Damien / Donner, Jannik / Liu, Lin / Pilon, Sarah-Jeanne / Fraser, Richard / Jorth, Peter / Newman, Dianne K / Brochiero, Emmanuelle / Rousseau, Simon / Nguyen, Dao

    American journal of respiratory and critical care medicine

    2024  

    Abstract: Rationale: Pseudomonas aeruginosa: Objectives: To detect and characterize intracellular : Methods: We sampled the lung explant tissues from CF patients undergoing lung transplantation and non-CF lung donor control. We analyzed lung tissue sections ...

    Abstract Rationale: Pseudomonas aeruginosa
    Objectives: To detect and characterize intracellular
    Methods: We sampled the lung explant tissues from CF patients undergoing lung transplantation and non-CF lung donor control. We analyzed lung tissue sections for the presence of intracellular
    Measurements and main results: P.a.
    Conclusion: This is the first study describing the presence of intracellular
    Language English
    Publishing date 2024-02-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202308-1451OC
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book: Fraser and Paré's diagnosis of diseases of the chest / 2

    Fraser, Robert G. / Paré, J. A. Peter / Fraser, Richard S.

    1999  

    Author's details R. S. Fraser
    Collection Fraser and Paré's diagnosis of diseases of the chest
    Language English
    Size XIII S., S. 697 - 1417, I-61 S. : Ill.
    Publisher Saunders
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT011102775
    ISBN 0-7216-6196-3 ; 978-0-7216-6196-4
    Database Catalogue ZB MED Medicine, Health

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  9. Book: Fraser and Paré's diagnosis of diseases of the chest / 1

    Fraser, Robert G. / Paré, J. A. Peter / Fraser, Richard S.

    1999  

    Author's details R. S. Fraser
    Collection Fraser and Paré's diagnosis of diseases of the chest
    Language English
    Size XLII, 693, I-61 S. : Ill.
    Publisher Saunders
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT011102796
    ISBN 0-7216-6195-5 ; 978-0-7216-6195-7
    Database Catalogue ZB MED Medicine, Health

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  10. Book: Fraser and Paré's diagnosis of diseases of the chest / 3

    Fraser, Robert G. / Paré, J. A. Peter / Fraser, Richard S.

    1999  

    Author's details R. S. Fraser
    Collection Fraser and Paré's diagnosis of diseases of the chest
    Language English
    Size XIII S., S. 1421 - 2357, I-61 S. : Ill., graph. Darst.
    Publisher Saunders
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT011102771
    ISBN 0-7216-6197-1 ; 978-0-7216-6197-1
    Database Catalogue ZB MED Medicine, Health

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