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  1. Article ; Online: A conversation with Joseph F. Fraumeni, Jr. Interviewed by Robert N. Hoover.

    Fraumeni, Joseph F

    Epidemiology (Cambridge, Mass.)

    2013  Volume 24, Issue 6, Page(s) 929–933

    MeSH term(s) Career Choice ; Epidemiology/history ; History, 20th Century ; Humans ; Mentors ; National Cancer Institute (U.S.)/history ; National Cancer Institute (U.S.)/organization & administration ; Neoplasms/epidemiology ; Physicians/history ; Physicians/psychology ; United States
    Language English
    Publishing date 2013-11
    Publishing country United States
    Document type Biography ; Historical Article ; Interview ; Portraits
    ZDB-ID 1053263-8
    ISSN 1531-5487 ; 1044-3983
    ISSN (online) 1531-5487
    ISSN 1044-3983
    DOI 10.1097/EDE.0b013e3182a56987
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3121: Show issues Location:
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  2. Book ; Conference proceedings: Persons at high risk of cancer

    Fraumeni, Joseph Francis

    an approach to cancer etiology and control ; proceedings of a conference Key Biscayne, Florida, December 10 - 12, 1974

    1975  

    Author's details ed. by Joseph F[rancis] Fraumeni
    Language English
    Size XVII, 544 S. ; 8-o
    Publisher Acad. Press
    Publishing place New York, NY u.a.
    Publishing country United States
    Document type Book ; Conference proceedings
    HBZ-ID HT009487063
    ISBN 0-12-265950-3 ; 978-0-12-265950-8
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    1977 A 382 order for loan Magazin

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  3. Article: Molecular epidemiology: principles and practices. Foreword.

    Fraumeni, Joseph F

    IARC scientific publications

    2011  , Issue 163, Page(s) vi

    MeSH term(s) Humans ; Molecular Epidemiology ; Public Health/trends
    Language English
    Publishing date 2011
    Publishing country France
    Document type Introductory Journal Article
    ISSN 0300-5038
    ISSN 0300-5038
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Reproductive factors associated with breast cancer risk in Li-Fraumeni syndrome.

    Khincha, Payal P / Best, Ana F / Fraumeni, Joseph F / Loud, Jennifer T / Savage, Sharon A / Achatz, Maria Isabel

    European journal of cancer (Oxford, England : 1990)

    2019  Volume 116, Page(s) 199–206

    Abstract: Li-Fraumeni syndrome (LFS) is a rare autosomal dominant cancer predisposition syndrome with exceptionally high lifetime cancer risks, caused primarily by germline TP53 variants. Early-onset breast cancer is the most common cancer in women with LFS. ... ...

    Abstract Li-Fraumeni syndrome (LFS) is a rare autosomal dominant cancer predisposition syndrome with exceptionally high lifetime cancer risks, caused primarily by germline TP53 variants. Early-onset breast cancer is the most common cancer in women with LFS. Associations between female reproductive factors and breast cancer risk have been widely studied in the general population and BRCA1/2 mutation carriers but not in LFS. We evaluated whether reproductive factors are associated with breast cancer in LFS. Questionnaire data were collected for 152 women with confirmed germline TP53 variants enrolled in the National Cancer Institute's LFS study (NCT01443468); of which, 85 had breast cancer, confirmed by pathology/medical reports. Fisher's exact test and Cox proportional hazards were used to calculate the effect of reproductive factors on breast cancer risk. Lifetime breastfeeding for at least 7 months was associated with lower breast cancer risk (hazard ratio [HR] 0.57, p = 0.05). Parity did not independently change breast cancer risk (HR 1.08, p = 0.8) but suggested an increased risk with older age at first live birth (HR 2.14, p = 0.05). Age at menarche (HR 1.09, p = 0.24) and use of oral contraceptives (HR 0.88; p = 0.7) did not significantly affect breast cancer risk. In this first study of reproductive factors and breast cancer in women with LFS, breastfeeding was observed to be protective against breast cancer risk, especially with at least 7 months of lifetime breastfeeding. Older age at first live birth was suggested to slightly increase breast cancer risk. Larger prospective studies of reproductive factors are warranted in women with LFS before making definitive clinical recommendations.
    MeSH term(s) Adult ; Breast Feeding ; Breast Neoplasms/etiology ; Contraceptives, Oral, Hormonal/therapeutic use ; Female ; Humans ; Li-Fraumeni Syndrome/complications ; Menarche/physiology ; Middle Aged ; Parity/physiology ; Retrospective Studies ; Risk Factors ; Young Adult
    Chemical Substances Contraceptives, Oral, Hormonal
    Language English
    Publishing date 2019-06-15
    Publishing country England
    Document type Journal Article ; Observational Study ; Research Support, N.I.H., Intramural
    ZDB-ID 82061-1
    ISSN 1879-0852 ; 0277-5379 ; 0959-8049 ; 0964-1947
    ISSN (online) 1879-0852
    ISSN 0277-5379 ; 0959-8049 ; 0964-1947
    DOI 10.1016/j.ejca.2019.05.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 456: Show issues Location:
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    Zs.MO 583: Show issues

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  5. Book: Cancer epidemiology and prevention

    Schottenfeld, David / Fraumeni, Joseph F

    2006  

    Author's details edited by David Schottenfeld, Joseph F. Fraumeni Jr
    MeSH term(s) Neoplasms/epidemiology ; Neoplasms/prevention & control
    Language English
    Size xviii, 1392 p. :, ill.
    Edition 3rd ed.
    Publisher Oxford University Press
    Publishing place Oxford ; New York
    Document type Book
    ISBN 9780195149616 ; 0195149610
    Database Catalogue of the US National Library of Medicine (NLM)

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  6. Article ; Online: The Changing Face of Noncardia Gastric Cancer Incidence Among US Non-Hispanic Whites.

    Anderson, William F / Rabkin, Charles S / Turner, Natalie / Fraumeni, Joseph F / Rosenberg, Philip S / Camargo, M Constanza

    Journal of the National Cancer Institute

    2018  Volume 110, Issue 6, Page(s) 608–615

    Abstract: Background: The initial step for noncardia gastric carcinogenesis is atrophic gastritis, driven by either Helicobacter pylori infection or autoimmunity. In recent decades, the prevalence rates of these two major causes declined and increased, ... ...

    Abstract Background: The initial step for noncardia gastric carcinogenesis is atrophic gastritis, driven by either Helicobacter pylori infection or autoimmunity. In recent decades, the prevalence rates of these two major causes declined and increased, respectively, with changes in Western lifestyles. We therefore assessed gastric cancer incidence trends for US race/ethnic groups, 1995-2013.
    Methods: Age-standardized rates (ASRs) from 45 North American Association of Central Cancer Tumor Registries were summarized by estimated annual percentage change (EAPC) and 95% confidence intervals (CIs). Age period cohort models supplemented standard descriptive techniques and projected future trends.
    Results: There were 137 447 noncardia cancers in 4.4 billion person-years of observation. Among non-Hispanic whites, the ASR was 2.2 per 100 000 person-years, with an EAPC of -2.3% (95% CI = -2.0% to -2.6%). Notwithstanding this overall decline, EAPCs rose 1.3% (95% CI = 0.6% to 2.1%) for persons younger than age 50 years and fell -2.6% (95% CI = -2.4% to -2.9%) for older individuals. These converging trends manifested a birth cohort effect more pronounced among women than men, with incidence among women born in 1983 twofold (95% CI = 1.1-fold to 3.6-fold) greater than those born in 1951. Age interaction was also statistically significant among Hispanic whites, with slightly increasing vs decreasing EAPCs for younger and older individuals, respectively. Incidence declined regardless of age for other races. Current trends foreshadow expected reversals in both falling incidence and male predominance among non-Hispanic whites.
    Conclusions: Dysbiosis of the gastric microbiome associated with modern living conditions may be increasing risk of autoimmune gastritis and consequent noncardia cancer. The changing face by age and sex of gastric cancer warrants analytical studies to identify potential causal mechanisms.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Cohort Studies ; Ethnicity/statistics & numerical data ; Female ; Helicobacter Infections/complications ; Helicobacter Infections/epidemiology ; Humans ; Incidence ; Male ; Middle Aged ; Prevalence ; Racial Groups/statistics & numerical data ; Registries ; Stomach Neoplasms/epidemiology ; Stomach Neoplasms/ethnology ; United States ; White People/statistics & numerical data
    Language English
    Publishing date 2018-01-31
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Intramural
    ZDB-ID 2992-0
    ISSN 1460-2105 ; 0027-8874 ; 0198-0157
    ISSN (online) 1460-2105
    ISSN 0027-8874 ; 0198-0157
    DOI 10.1093/jnci/djx262
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  7. Article ; Online: Hair dye use and non-Hodgkin lymphoma.

    Zahm, Shelia Hoar / Fraumeni, Joseph F

    JAMA

    2005  Volume 294, Issue 10, Page(s) 1205; author reply 1205

    MeSH term(s) Hair Dyes/adverse effects ; Humans ; Lymphoma, Non-Hodgkin/chemically induced ; Risk Factors
    Chemical Substances Hair Dyes
    Language English
    Publishing date 2005-09-14
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 2958-0
    ISSN 1538-3598 ; 0254-9077 ; 0002-9955 ; 0098-7484
    ISSN (online) 1538-3598
    ISSN 0254-9077 ; 0002-9955 ; 0098-7484
    DOI 10.1001/jama.294.10.1205-a
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  8. Article: Outstanding Scientist of 2004. Joseph K. McLaughlin, PhD: A world leader in implant research.

    Blot, William J / Fraumeni, Joseph F

    Journal of long-term effects of medical implants

    2004  Volume 14, Issue 5, Page(s) 341–346

    Abstract: Objective: To describe the key contributions of Dr. Joseph K. McLaughlin, Outstanding Scientist of 2004.: Methods: We review the scientific literature and indicate how epidemiologic research conducted by Dr. McLaughlin has clarified long-term health ... ...

    Abstract Objective: To describe the key contributions of Dr. Joseph K. McLaughlin, Outstanding Scientist of 2004.
    Methods: We review the scientific literature and indicate how epidemiologic research conducted by Dr. McLaughlin has clarified long-term health effects among persons with breast and other medical implants.
    Results: Dr. Joseph K. McLaughlin has conducted and directed more research into the long-term effects of human implants than any other scientist worldwide. His insights greatly elucidated the long-term health consequences associated with a variety of implanted devices, including silicone and saline breast implants, hip and knee replacements, temporomandibular and finger joint devices, and pacemakers. By initiating and bringing to fruition a series of innovative epidemiologic investigations, Dr. McLaughlin and his colleagues have provided the scientific basis for making judgments about alleged adverse health effects following cosmetic, reconstructive, and reparative implant surgery.
    Conclusions: Dr. McLaughlin's seminal investigations have provided reassurance that breast and other implants have not demonstrably increased the risk of cancer or other systemic diseases. The comprehensive and rigorous nature of this research merits his selection as Outstanding Scientist of 2004.
    MeSH term(s) Awards and Prizes ; Breast Implants ; Epidemiology/history ; History, 21st Century ; Humans ; Maryland ; Prostheses and Implants ; Societies, Medical ; United States
    Language English
    Publishing date 2004-09-01
    Publishing country United States
    Document type Biography ; Historical Article ; Journal Article ; Portrait
    ZDB-ID 1073166-0
    ISSN 1050-6934
    ISSN 1050-6934
    DOI 10.1615/jlongtermeffmedimplants.v14.i5.10
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3217: Show issues Location:
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  9. Book: Epidemiology of cancer

    Fraumeni, Joseph F

    an interdisciplinary approach

    (NIH director's Wednesday afternoon lecture series. Robert S. Gordon, Jr. lecture)

    1996  

    Institution National Institutes of Health (U.S.). / Medical Arts and Photography Branch
    Author's details Medical Arts and Photography Branch
    Series title NIH director's Wednesday afternoon lecture series. Robert S. Gordon, Jr. lecture
    MeSH term(s) Neoplasms/epidemiology ; Genetic Predisposition to Disease ; Neoplasms/genetics ; Risk Factors
    Language English
    Size 1 videocassette (53 min.) :, sd., col. ;, 1/2 in.
    Publisher National Institutes of Health
    Publishing place Bethesda, Md
    Document type Book
    Note CME credit available.
    Database Catalogue of the US National Library of Medicine (NLM)

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  10. Book: Epidemiology of cancer

    Fraumeni, Joseph F

    an interdisciplinary approach

    (The 1996 Robert S. Gordon, Jr. lecture in epidemiology)

    1996  

    Abstract: An orange eight-pointed star is the center of the image, with blue rays coming from it over a background of light green, red, and yellow shapes. The date of the lecture is Wednesday, Nov. 13, 1996. ...

    Institution National Institutes of Health (U.S.). / Medical Arts and Photography Branch
    Author's details Joseph F. Fraumeni Jr
    Series title The 1996 Robert S. Gordon, Jr. lecture in epidemiology
    Abstract An orange eight-pointed star is the center of the image, with blue rays coming from it over a background of light green, red, and yellow shapes. The date of the lecture is Wednesday, Nov. 13, 1996.
    MeSH term(s) Neoplasms/epidemiology
    Language English
    Size 1 photomechanical print (poster) :, col. ;, 78 x 46 cm.
    Publisher Medical Arts and Photography Branch, National Institutes of Health
    Publishing place Bethesda, Md
    Document type Book
    Note HMD provides access to digital images in lieu of originals when electronic copies exist. Access to originals may require advance notice. Please see HMD Reference Librarian for more information.
    Database Catalogue of the US National Library of Medicine (NLM)

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