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  1. Article ; Online: Occurrence and Biological Activities of Seco-Iridoids from Jasminum L.

    Frezza, Claudio / Nicolosi, Roberta Maria / Brasili, Elisa / Mura, Francesco / De Vita, Daniela

    Chemistry & biodiversity

    2024  Volume 21, Issue 4, Page(s) e202400254

    Abstract: In this paper, the first complete review on the seco-iridoids from the genus Jasminum L. was presented. In particular, their occurrence in the genus was detailed together with their biological activities. The literature survey has clearly pointed out ... ...

    Abstract In this paper, the first complete review on the seco-iridoids from the genus Jasminum L. was presented. In particular, their occurrence in the genus was detailed together with their biological activities. The literature survey has clearly pointed out that only a few Jasminum species have been studied for their seco-iridoid content evidencing oleoside derivatives as main compounds. In addition, the biological studies performed on them are very scarce focusing mainly on antioxidant and anti-inflammatory assays with modest effectiveness. All these results greatly underline the need for further in-depth analyses on these compounds under both the aspects.
    MeSH term(s) Iridoids ; Jasminum ; Anti-Inflammatory Agents/pharmacology
    Chemical Substances Iridoids ; Anti-Inflammatory Agents
    Language English
    Publishing date 2024-03-15
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2139001-0
    ISSN 1612-1880 ; 1612-1872
    ISSN (online) 1612-1880
    ISSN 1612-1872
    DOI 10.1002/cbdv.202400254
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: An overview of the genus Aloysia Paláu (Verbenaceae): Essential oil composition, ethnobotany and biological activities

    Mohammadhosseini, Majid / Frezza, Claudio / Venditti, Alessandro / Mahdavi, Behnam

    Natural product research. 2022 Sept. 21, v. 36, no. 19

    2022  

    Abstract: Aloysia Paláu is an important herbal genus from the Verbenaceae family and possesses numerous remedial properties in the folk medicine of Asian, European, and, in particular, South American countries. Only a few reports have discussed some phytochemical ... ...

    Abstract Aloysia Paláu is an important herbal genus from the Verbenaceae family and possesses numerous remedial properties in the folk medicine of Asian, European, and, in particular, South American countries. Only a few reports have discussed some phytochemical characteristics associated with Aloysia species. Right the lack of an exhaustive report prompted us to organize this review article. Accordingly, besides the ethnobotanical knowledge of Aloysia species, their essential oil profiles, phytochemistry of the polar isolated fractions, and the relevant biological activities are discussed in detail.
    Keywords Aloysia ; essential oils ; ethnobotany ; research ; traditional medicine
    Language English
    Dates of publication 2022-0921
    Size p. 5091-5107.
    Publishing place Taylor & Francis
    Document type Article
    ZDB-ID 2185747-7
    ISSN 1478-6427 ; 1478-6419
    ISSN (online) 1478-6427
    ISSN 1478-6419
    DOI 10.1080/14786419.2021.1907576
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  3. Article ; Online: Phytochemical analysis on the leaves of Agathis microstachya J.F. Bailey & C.T. White

    Frezza, Claudio / Sciubba, Fabio / Petrucci, Rita / Serafini, Mauro

    Natural Product Research. 2022 Nov. 1, v. 36, no. 21 p.5626-5630

    2022  

    Abstract: The first phytochemical analysis on the leaves of Agathis microstachya J.F. Bailey & C.T. White collected in Rome was reported in this work. The study evidenced the presence of four compounds i.e., 7,4'''-dimethoxy-agathisflavone (1), 7,7''-dimethoxy- ... ...

    Abstract The first phytochemical analysis on the leaves of Agathis microstachya J.F. Bailey & C.T. White collected in Rome was reported in this work. The study evidenced the presence of four compounds i.e., 7,4'''-dimethoxy-agathisflavone (1), 7,7''-dimethoxy-cupressuflavone (2), dactylifric acid (3) and shikimic acid (4) which were identified by means of spectroscopic techniques. Compounds (1, 2, 4) were reported in the species for the first time as well as this is the second report on the presence of dactylifric acid (3) in the whole Araucariaceae family. The absence of diterpenoids from the studied accession is also important. All these chemotaxonomic aspects were discussed.
    Keywords Araucariaceae ; chemotaxonomy ; diterpenoids ; phytochemicals ; research ; shikimic acid ; spectroscopy ; Agathis microstachya J.F.Bailey & C.T.White ; phytochemical analysis
    Language English
    Dates of publication 2022-1101
    Size p. 5626-5630.
    Publishing place Taylor & Francis
    Document type Article ; Online
    ZDB-ID 2185747-7
    ISSN 1478-6427 ; 1478-6419
    ISSN (online) 1478-6427
    ISSN 1478-6419
    DOI 10.1080/14786419.2021.2018435
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  4. Article ; Online: Phytochemical analysis on the leaves of

    Frezza, Claudio / Sciubba, Fabio / Petrucci, Rita / Serafini, Mauro

    Natural product research

    2021  Volume 36, Issue 21, Page(s) 5626–5630

    Abstract: The first phytochemical analysis on the leaves ... ...

    Abstract The first phytochemical analysis on the leaves of
    MeSH term(s) Phytochemicals/analysis ; Plant Leaves/chemistry ; Araucariaceae ; Diterpenes/analysis
    Chemical Substances Phytochemicals ; Diterpenes
    Language English
    Publishing date 2021-12-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 2185747-7
    ISSN 1478-6427 ; 1478-6419
    ISSN (online) 1478-6427
    ISSN 1478-6419
    DOI 10.1080/14786419.2021.2018435
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: An overview of the genus

    Mohammadhosseini, Majid / Frezza, Claudio / Venditti, Alessandro / Mahdavi, Behnam

    Natural product research

    2021  Volume 36, Issue 19, Page(s) 5091–5107

    Abstract: ... ...

    Abstract Aloysia
    MeSH term(s) Ethnobotany ; Oils, Volatile/chemistry ; Oils, Volatile/pharmacology ; Palau ; Phytochemicals/chemistry ; Phytochemicals/pharmacology ; Plant Extracts/chemistry ; Verbenaceae/chemistry
    Chemical Substances Oils, Volatile ; Phytochemicals ; Plant Extracts
    Language English
    Publishing date 2021-04-11
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2185747-7
    ISSN 1478-6427 ; 1478-6419
    ISSN (online) 1478-6427
    ISSN 1478-6419
    DOI 10.1080/14786419.2021.1907576
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Phytochemical analysis on the seeds of a new Iranian Plantago ovata Forssk. population specimen

    Frezza, Claudio / Sciubba, Fabio / Tomai, Pierpaolo / Gentili, Alessandra / Bianco, Armandodoriano / Serafini, Mauro / Golkar, Pooran

    Natural product research. 2022 July 15, v. 36, no. 14

    2022  

    Abstract: In this paper, the phytochemical analysis of the seeds of a new Iranian Plantago ovata Forssk. population exemplar is reported. This phytochemical analysis was carried out by means of hydroalcoholic maceration, column chromatography, NMR and MS analyses ... ...

    Abstract In this paper, the phytochemical analysis of the seeds of a new Iranian Plantago ovata Forssk. population exemplar is reported. This phytochemical analysis was carried out by means of hydroalcoholic maceration, column chromatography, NMR and MS analyses and led to the isolation of sixteen compounds belonging to five different classes of natural compounds. After comparison with previous analyses, a clear difference about their whole phytochemical patterns could be observed in some terms. A possible explanation of this was generally given, too.
    Keywords Plantago ovata ; chromatography ; maceration ; phytochemicals ; research
    Language English
    Dates of publication 2022-0715
    Size p. 3761-3764.
    Publishing place Taylor & Francis
    Document type Article
    ZDB-ID 2185747-7
    ISSN 1478-6427 ; 1478-6419
    ISSN (online) 1478-6427
    ISSN 1478-6419
    DOI 10.1080/14786419.2021.1881960
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  7. Article ; Online: A Systematic Review on Phytochemistry, Ethnobotany and Biological Activities of the Genus Bunium L.

    Mohammadhosseini, Majid / Frezza, Claudio / Venditti, Alessandro / Sarker, Satyajit D

    Chemistry & biodiversity

    2021  Volume 18, Issue 11, Page(s) e2100317

    Abstract: The aim of this review article is to present, for the first time, an appraisal of the phytochemical, ethnobotanical and pharmacological data on Bunium species. The literature search was conducted using the Scopus, Google Scholar and PubMed databases. The ...

    Abstract The aim of this review article is to present, for the first time, an appraisal of the phytochemical, ethnobotanical and pharmacological data on Bunium species. The literature search was conducted using the Scopus, Google Scholar and PubMed databases. The genus Bunium has been found to produce both essential oil (EO), mainly comprising monoterpenes and sesquiterpenes, and non-volatile components mainly coumarins and flavonoids. There are several pharmacological activities associated with the Bunium species, especially antioxidant, antibacterial and antifungal properties. The chemotaxonomic appraisal of the phytochemical pattern of the genus is in sink with the current classification of the family. Moreover, this review confirms the significant ethnobotanical and pharmacological potential of different Bunium species.
    MeSH term(s) Animals ; Anti-Infective Agents/chemistry ; Anti-Infective Agents/isolation & purification ; Anti-Infective Agents/pharmacology ; Antioxidants/chemistry ; Antioxidants/isolation & purification ; Antioxidants/pharmacology ; Apiaceae/chemistry ; Bacteria/drug effects ; Benzothiazoles/antagonists & inhibitors ; Biphenyl Compounds/antagonists & inhibitors ; Ethnobotany ; Fungi/drug effects ; Humans ; Molecular Structure ; Phytochemicals/chemistry ; Phytochemicals/isolation & purification ; Phytochemicals/pharmacology ; Picrates/antagonists & inhibitors ; Plant Extracts/chemistry ; Plant Extracts/isolation & purification ; Plant Extracts/pharmacology ; Sulfonic Acids/antagonists & inhibitors
    Chemical Substances Anti-Infective Agents ; Antioxidants ; Benzothiazoles ; Biphenyl Compounds ; Phytochemicals ; Picrates ; Plant Extracts ; Sulfonic Acids ; 2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid (28752-68-3) ; 1,1-diphenyl-2-picrylhydrazyl (DFD3H4VGDH)
    Language English
    Publishing date 2021-10-20
    Publishing country Switzerland
    Document type Journal Article ; Systematic Review
    ZDB-ID 2139001-0
    ISSN 1612-1880 ; 1612-1872
    ISSN (online) 1612-1880
    ISSN 1612-1872
    DOI 10.1002/cbdv.202100317
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Phytochemical analysis and biological activities of the aerial parts of Odontites vulgaris Moench.

    Frezza, Claudio / De Vita, Daniela / Venditti, Alessandro / Baldani, Claudia / Giampaoli, Ottavia / Sciubba, Fabio / Bosco, Chiara Dal / Franceschin, Marco / Beccaccioli, Marzia / Reverberi, Massimo / Percaccio, Ester / Di Sotto, Antonella / Foddai, Sebastiano

    Fitoterapia

    2024  Volume 175, Page(s) 105936

    Abstract: In this work, the first specific phytochemical analysis on Odontites vulgaris Moench collected in Central Italy was performed. The aerial parts ethanolic extract was studied and eight compounds were identified: pheophytin a (1), aucubin (2), catalpol (3), ...

    Abstract In this work, the first specific phytochemical analysis on Odontites vulgaris Moench collected in Central Italy was performed. The aerial parts ethanolic extract was studied and eight compounds were identified: pheophytin a (1), aucubin (2), catalpol (3), shanzhiside methyl ester (4), melampyroside (5), 8-epi-loganin (6), caryoptoside (7) and quinic acid (8). To the best of our knowledge, in this study, compounds (7-8) resulted to be isolated from the genus for the first time. The chemophenetic markers of the family and order were evidenced and several important ecological conclusions could be drawn. The ethanolic extract was also tested for several biological activities showing high effects in the antioxidant, cytoprotective and aflatoxin B1 production inhibitory assays. A brief explanation on these activities under the phytochemical standpoint was also included.
    Language English
    Publishing date 2024-03-27
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 412385-2
    ISSN 1873-6971 ; 0367-326X
    ISSN (online) 1873-6971
    ISSN 0367-326X
    DOI 10.1016/j.fitote.2024.105936
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: First study on the pyrrolizidine alkaloids of Pardoglossum cheirifolium (L.) E.Barbier & Mathez.: GC-MS analysis of their volatile components in the whole plant

    Benamar, Houari / Tomassini, Lamberto / Frezza, Claudio / Marouf, Abderrazak / Bennaceur, Malika / Nicoletti, Marcello

    Natural product research. 2021 Nov. 2, v. 35, no. 21

    2021  

    Abstract: In this work, the first study on the pyrrolizidine alkaloids content of Pardoglossum cheirifolium (L.) E.Barbier & Mathez. was reported. The studied exemplar was collected in Algeria and the analysis was carried out by means of GC-MS on the crude base ... ...

    Abstract In this work, the first study on the pyrrolizidine alkaloids content of Pardoglossum cheirifolium (L.) E.Barbier & Mathez. was reported. The studied exemplar was collected in Algeria and the analysis was carried out by means of GC-MS on the crude base extract deriving from the whole plant. Nine compounds were tentatively identified and they all represent new phytochemicals at the species level. Their presence confirms the botanical classification of the plant as a member of the Boraginaceae family. In addition, it points out some interesting chemosystematic relations within the family.
    Keywords Boraginaceae ; phytochemicals ; research ; Algeria
    Language English
    Dates of publication 2021-1102
    Size p. 4098-4103.
    Publishing place Taylor & Francis
    Document type Article
    ZDB-ID 2185747-7
    ISSN 1478-6427 ; 1478-6419
    ISSN (online) 1478-6427
    ISSN 1478-6419
    DOI 10.1080/14786419.2020.1721491
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  10. Article ; Online: Phytochemical analysis on the aerial parts of Teucrium capitatum L. with aspects of chemosystematics and ethnobotany

    Frezza, Claudio / Bozzato, Gianluca / Sciubba, Fabio / Serafini, Ilaria / Franceschin, Marco / Curini, Roberta / Cianfaglione, Kevin / Venditti, Alessandro / Bianco, Armandodoriano / Serafini, Mauro / Foddai, Sebastiano

    Natural Product Research. 2023 July 18, v. 37, no. 14 p.2398-2407

    2023  

    Abstract: The phytochemical analysis on the aerial parts of Teucrium capitatum L. collected from a new population in Central Italy, led to the identification of eight compounds, i.e. pheophytin a (1), poliumoside (2), apigenin (3), luteolin (4), cirsimaritin (5), ... ...

    Abstract The phytochemical analysis on the aerial parts of Teucrium capitatum L. collected from a new population in Central Italy, led to the identification of eight compounds, i.e. pheophytin a (1), poliumoside (2), apigenin (3), luteolin (4), cirsimaritin (5), cirsiliol (6), 8-O-acetyl-harpagide (7) and teucardoside (8) belonging to four different classes of secondary metabolites. Pheophytin a (1) represents a newly identified compound in the genus whereas compounds (7-8) are newly identified compound in the species. The chemotaxonomic and ethnobotanical aspects relative to the presence of these compounds were widely discussed suggesting important conclusions for both.
    Keywords Teucrium polium subsp. capitatum ; apigenin ; chemotaxonomy ; ethnobotany ; luteolin ; research ; secondary metabolites ; Italy ; Teucrium capitatum L. ; new population ; Central Italy ; phytochemistry ; ethnobotanical aspects
    Language English
    Dates of publication 2023-0718
    Size p. 2398-2407.
    Publishing place Taylor & Francis
    Document type Article ; Online
    ZDB-ID 2185747-7
    ISSN 1478-6427 ; 1478-6419
    ISSN (online) 1478-6427
    ISSN 1478-6419
    DOI 10.1080/14786419.2022.2081967
    Database NAL-Catalogue (AGRICOLA)

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