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  1. Book: Programmierte Untersuchung des Bewegungsapparates

    Frisch, Herbert

    Chirotherapie und Osteopathie im Vergleich

    2009  

    Author's details Herbert Frisch
    Keywords Musculoskeletal System ; Physical Examination ; Muscular Diseases / diagnosis ; Joint Diseases / diagnosis ; Bone Diseases / diagnosis ; Bewegungsapparat ; Krankheit ; Diagnose
    Subject Ärztliche Diagnose ; Erkrankung ; Krankheitszustand ; Krankheiten ; Morbus ; Nosos ; Pathos ; Bewegungsorgan ; Stützapparat ; Haltungsapparat
    Language German
    Size X, 776 S. : Ill., graph. Darst.
    Edition 9., überarb. und erw. Aufl.
    Publisher Springer
    Publishing place Heidelberg
    Publishing country Germany
    Document type Book
    HBZ-ID HT015331519
    ISBN 978-3-540-72854-2 ; 3-540-72854-6
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2008 A 7742 order for loan Magazin
    2009 A 2966 order for loan Magazin

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  2. Article ; Online: pH-Controlled Reversible Folding of Copolymers via Formation of β-sheet Secondary Structures.

    Sbordone, Federica / Micallef, Aaron / Frisch, Hendrik

    Angewandte Chemie (International ed. in English)

    2024  Volume 63, Issue 10, Page(s) e202319839

    Abstract: Protein functions are enabled by their perfectly arranged 3D structure, which is the result of a hierarchical intramolecular folding process. Sequence-defined polypeptide chains form locally ordered secondary structures (i.e., α-helix and β-sheet) ... ...

    Abstract Protein functions are enabled by their perfectly arranged 3D structure, which is the result of a hierarchical intramolecular folding process. Sequence-defined polypeptide chains form locally ordered secondary structures (i.e., α-helix and β-sheet) through hydrogen bonding between the backbone amides, shaping the overall tertiary structure. To generate similarly complex macromolecular architectures based on synthetic materials, a plethora of strategies have been developed to induce and control the folding of synthetic polymers. However, the degree of complexity of the structure-driving ensemble of interactions demonstrated by natural polymers is unreached, as synthesizing long sequence-defined polymers with functional backbones remains a challenge. Herein, we report the synthesis of hybrid peptide-N,N-Dimethylacrylamide copolymers via radical Ring-Opening Polymerization (rROP) of peptide containing macrocycles. The resulting synthetic polymers contain sequence-defined regions of β-sheet encoding amino acid sequences. Exploiting the pH responsiveness of the embedded sequences, protonation or deprotonation in water induces self-assembly of the peptide strands at an intramacromolecular level, driving polymer chain folding via formation of β-sheet secondary structures. We demonstrate that the folding behavior is sequence dependent and reversible.
    MeSH term(s) Protein Conformation, beta-Strand ; Peptides/chemistry ; Proteins/chemistry ; Polymers/chemistry ; Hydrogen-Ion Concentration ; Protein Folding
    Chemical Substances Peptides ; Proteins ; Polymers
    Language English
    Publishing date 2024-01-24
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2011836-3
    ISSN 1521-3773 ; 1433-7851
    ISSN (online) 1521-3773
    ISSN 1433-7851
    DOI 10.1002/anie.202319839
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book: Programmierte Therapie am Bewegungsapparat

    Frisch, Herbert

    Chirotherapie - Osteopathie - Physiotherapie

    2003  

    Author's details Herbert Frisch
    Keywords Chiropractic ; Manuelle Medizin
    Subject Manuelle Therapie ; Chirotherapie ; Manualtherapie ; Chiropraktik
    Language German
    Size XX, 814 S. : zahlr. Ill., graph. Darst.
    Edition 4., überarb. und erg. Aufl.
    Publisher Springer
    Publishing place Berlin u.a.
    Publishing country Germany
    Document type Book
    HBZ-ID HT013452719
    ISBN 3-540-43540-9 ; 978-3-540-43540-2
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2002 A 5646 order for loan Magazin
    2004 A 8851 order for loan Magazin

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  4. Book: Programmierte Untersuchung des Bewegungsapparates

    Frisch, Herbert

    Chirodiagnostik ; mit 16 Tabellen

    2001  

    Author's details Herbert Frisch
    Keywords Bewegungsapparat ; Krankheit ; Diagnose
    Subject Ärztliche Diagnose ; Erkrankung ; Krankheitszustand ; Krankheiten ; Morbus ; Nosos ; Pathos ; Bewegungsorgan ; Stützapparat ; Haltungsapparat
    Language German
    Size XII, 719 S. : Ill., graph. Darst.
    Edition 8., überarb. Aufl.
    Publisher Springer
    Publishing place Berlin u.a.
    Publishing country Germany
    Document type Book
    HBZ-ID HT012999767
    ISBN 3-540-41049-X ; 978-3-540-41049-2
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2001 A 2379 order for loan Magazin

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  5. Article ; Online: Programming Photodegradability into Vinylic Polymers via Radical Ring-Opening Polymerization.

    Do, Phuong T / Poad, Berwyck L J / Frisch, Hendrik

    Angewandte Chemie (International ed. in English)

    2023  Volume 62, Issue 6, Page(s) e202213511

    Abstract: Incorporation of photolabile moieties into the polymer backbone holds promise to remotely-control polymer degradation. However, suitable synthetic avenues are limited, especially for radical polymerizations. Here we report a strategy to program ... ...

    Abstract Incorporation of photolabile moieties into the polymer backbone holds promise to remotely-control polymer degradation. However, suitable synthetic avenues are limited, especially for radical polymerizations. Here we report a strategy to program photodegradability into vinylic polymers by exploiting the wavelength selectivity of photocycloadditions for radical ring-opening polymerization (rROP). Irradiation of coumarin terminated allylic sulfides with UVA light initiated intramolecular [2+2] photocycloaddition producing cyclic macromonomers. Subsequent RAFT-mediated rROP with methyl acrylate yielded copolymers that inherited the photoreactivity of the cyclic parent monomer. Irradiation with UVB initiated efficient photocycloreversion of the coumarin dimers, causing polymer degradation within minutes under UVB light or days under sunlight exposure. Our synthetic strategy may pave the way to insert photolabile linkages into vinylic polymers, tuning degradation for specific wavelengths.
    Language English
    Publishing date 2023-01-09
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2011836-3
    ISSN 1521-3773 ; 1433-7851
    ISSN (online) 1521-3773
    ISSN 1433-7851
    DOI 10.1002/anie.202213511
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book: Programmierte Untersuchung des Bewegungsapparates

    Frisch, Herbert

    Chirodiagnostik ; mit 16 Tabellen

    1998  

    Author's details Herbert Frisch
    Keywords Bone Diseases / diagnosis ; Muscular Diseases / diagnosis ; Spinal Diseases / diagnosis ; Bewegungsapparat ; Krankheit ; Diagnose
    Subject Ärztliche Diagnose ; Erkrankung ; Krankheitszustand ; Krankheiten ; Morbus ; Nosos ; Pathos ; Bewegungsorgan ; Stützapparat ; Haltungsapparat
    Language German
    Size XII, 717 S. : zahlr. Ill.
    Edition 7., neubearb. und erg. Aufl.
    Publisher Springer
    Publishing place Berlin u.a.
    Publishing country Germany
    Document type Book
    HBZ-ID HT008379739
    ISBN 3-540-63153-4 ; 978-3-540-63153-8
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1998 A 4396 order for loan Magazin

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  7. Book: Programmierte Therapie am Bewegungsapparat

    Frisch, Herbert

    Chirotherapie

    1996  

    Author's details Herbert Frisch
    Keywords Chiropractic ; Manuelle Medizin
    Subject Manuelle Therapie ; Chirotherapie ; Manualtherapie ; Chiropraktik
    Language German
    Size XVII, 756 S. : zahlr. Ill.
    Edition 2., korrigierte Aufl.
    Publisher Springer
    Publishing place Berlin u.a.
    Publishing country Germany
    Document type Book
    Note Literaturverz. S. [728] - 733
    HBZ-ID HT007367085
    ISBN 3-540-61324-2 ; 978-3-540-61324-4
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1997 A 1593a order for loan Magazin
    1997 A 1593a order for loan Magazin
    1997 A 1593 order for loan Magazin

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  8. Article: Förster resonance energy transfer within single chain nanoparticles.

    Maag, Patrick H / Feist, Florian / Frisch, Hendrik / Roesky, Peter W / Barner-Kowollik, Christopher

    Chemical science

    2024  Volume 15, Issue 14, Page(s) 5218–5224

    Abstract: Single chain nanoparticles (SCNPs) are a highly versatile polymer architecture consisting of single polymer chains that are intramolecularly crosslinked. Currently, SCNPs are discussed as powerful macromolecular architectures for catalysis, delivery and ... ...

    Abstract Single chain nanoparticles (SCNPs) are a highly versatile polymer architecture consisting of single polymer chains that are intramolecularly crosslinked. Currently, SCNPs are discussed as powerful macromolecular architectures for catalysis, delivery and sensors. Herein, we introduce a methodology based on Förster Resonance Energy Transfer (FRET) to evidence the folding of single polymer chains into SCNPs
    Language English
    Publishing date 2024-02-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 2559110-1
    ISSN 2041-6539 ; 2041-6520
    ISSN (online) 2041-6539
    ISSN 2041-6520
    DOI 10.1039/d3sc06651g
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Photochemical Action Plots Reveal Red-shifted Wavelength-dependent Photoproduct Distributions.

    Carroll, Joshua A / Pashley-Johnson, Fred / Frisch, Hendrik / Barner-Kowollik, Christopher

    Chemistry (Weinheim an der Bergstrasse, Germany)

    2024  Volume 30, Issue 23, Page(s) e202304174

    Abstract: Photochemical action plots are a powerful tool for mapping photochemical reaction outcomes wavelength-by-wavelength. Typically, they map either the depletion of a reactant or the formation of a specific product as a function of wavelength. Herein, we ... ...

    Abstract Photochemical action plots are a powerful tool for mapping photochemical reaction outcomes wavelength-by-wavelength. Typically, they map either the depletion of a reactant or the formation of a specific product as a function of wavelength. Herein, we exploit action plots to simultaneously map the formation of several photochemical products from a single chromophore. We demonstrate that the wavelength-resolved mapping of two reaction products formed during the irradiation of a chalcone species not only shows wavelength dependence - exhibiting the typical strong red-shift of the photochemical reactivity compared to the absorbance spectrum of the chromophore - but also a strong wavelength selectivity with remarkably different product distributions resulting from different irradiation wavelengths.
    Language English
    Publishing date 2024-02-09
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1478547-X
    ISSN 1521-3765 ; 0947-6539
    ISSN (online) 1521-3765
    ISSN 0947-6539
    DOI 10.1002/chem.202304174
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Book: Programmierte Therapie am Bewegungsapparat

    Frisch, Herbert

    Chirotherapie

    1995  

    Author's details Herbert Frisch
    Keywords Chiropractic ; Manuelle Medizin
    Subject Manuelle Therapie ; Chirotherapie ; Manualtherapie ; Chiropraktik
    Language German
    Size XVII, 751 S. : zahlr. Ill., graph. Darst.
    Publisher Springer
    Publishing place Berlin u.a.
    Publishing country Germany
    Document type Book
    HBZ-ID HT006739051
    ISBN 3-540-57857-9 ; 978-3-540-57857-4
    Database Catalogue ZB MED Medicine, Health

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1995 A 4512 order for loan Magazin

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