LIVIVO - Das Suchportal für Lebenswissenschaften

switch to English language
Erweiterte Suche

Ihre letzten Suchen

  1. AU="Fritz, Cassandra Dl"
  2. AU="Sommer, Norbert"
  3. AU="Brandão, Claudia Valeria S"
  4. AU="Jesky, Mark D"
  5. AU="Filipe de Oliveira"
  6. AU="Chang, Shantel"
  7. AU="Mbow, M Lamine"
  8. AU="Sekhon, M."
  9. AU="Song, Y-S"
  10. AU="Collins, Brooke"
  11. AU="Ali Al-Naji"
  12. AU="Bansal, Bhavtosh"
  13. AU="De Cremer, Kaat"
  14. AU="O'Neil, James"
  15. AU=White Tonya
  16. AU="Clark-Deener, Sherrie"
  17. AU="Ishak Yassir"
  18. AU="Chih-Wei Chen"

Suchergebnis

Treffer 1 - 2 von insgesamt 2

Suchoptionen

  1. Artikel ; Online: Gastroenterology climate action opportunities via education, empowerment of trainees and research.

    Shaukat, Aasma / Shah, Brijen / Fritz, Cassandra Dl / Omary, M Bishr

    Gut

    2023  Band 72, Heft 12, Seite(n) 2219–2221

    Mesh-Begriff(e) Humans ; Gastroenterology/education ; Educational Status ; Gastrointestinal Tract ; Education, Medical, Graduate
    Sprache Englisch
    Erscheinungsdatum 2023-11-24
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 80128-8
    ISSN 1468-3288 ; 0017-5749
    ISSN (online) 1468-3288
    ISSN 0017-5749
    DOI 10.1136/gutjnl-2023-331093
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  2. Artikel ; Online: Metabolic syndrome, metabolic comorbid conditions and risk of early-onset colorectal cancer.

    Chen, Hanyu / Zheng, Xiaobin / Zong, Xiaoyu / Li, Zitong / Li, Na / Hur, Jinhee / Fritz, Cassandra Dl / Chapman, William / Nickel, Katelin B / Tipping, Andrew / Colditz, Graham A / Giovannucci, Edward L / Olsen, Margaret A / Fields, Ryan C / Cao, Yin

    Gut

    2020  Band 70, Heft 6, Seite(n) 1147–1154

    Abstract: Objective: Factors that lead to metabolic dysregulation are associated with increased risk of early-onset colorectal cancer (CRC diagnosed under age 50). However, the association between metabolic syndrome (MetS) and early-onset CRC remains unexamined.!# ...

    Abstract Objective: Factors that lead to metabolic dysregulation are associated with increased risk of early-onset colorectal cancer (CRC diagnosed under age 50). However, the association between metabolic syndrome (MetS) and early-onset CRC remains unexamined.
    Design: We conducted a nested case-control study among participants aged 18-64 in the IBM MarketScan Commercial Database (2006-2015). Incident CRC was identified using pathologist-coded International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes, and controls were frequency matched. MetS was defined as presence of ≥3 conditions among obesity, hypertension, hyperlipidaemia and hyperglycaemia/type 2 diabetes, based on ICD-9-CM and use of medications. Multivariable logistic regressions were used to estimate ORs and 95% CIs.
    Results: MetS was associated with increased risk of early-onset CRC (n=4673; multivariable adjusted OR 1.25; 95% CI 1.09 to 1.43), similar to CRC diagnosed at age 50-64 (n=14 928; OR 1.21; 95% CI 1.15 to 1.27). Compared with individuals without a metabolic comorbid condition, those with 1, 2 or ≥3 conditions had a 9% (1.09; 95% CI 1.00 to 1.17), 12% (1.12; 95% CI 1.01 to 1.24) and 31% (1.31; 95% CI 1.13 to 1.51) higher risk of early-onset CRC (p
    Conclusions: Metabolic dysregulation was associated with increased risk of early-onset CRC, driven by proximal and distal colon cancer, thus at least in part contribute to the rising incidence of early-onset CRC.
    Mesh-Begriff(e) Adult ; Age of Onset ; Case-Control Studies ; Colon/pathology ; Colonic Neoplasms/epidemiology ; Comorbidity ; Databases, Factual ; Diabetes Mellitus, Type 2/epidemiology ; Female ; Humans ; Hyperglycemia/epidemiology ; Hyperlipidemias/epidemiology ; Hypertension/epidemiology ; Incidence ; Male ; Metabolic Syndrome/epidemiology ; Middle Aged ; Obesity/epidemiology ; Rectal Neoplasms/epidemiology ; United States/epidemiology
    Sprache Englisch
    Erscheinungsdatum 2020-10-09
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 80128-8
    ISSN 1468-3288 ; 0017-5749
    ISSN (online) 1468-3288
    ISSN 0017-5749
    DOI 10.1136/gutjnl-2020-321661
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

Zum Seitenanfang