LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 4 of total 4

Search options

  1. Article: The Hidden Cost of COVID-19: Focus on Antimicrobial Resistance in Bloodstream Infections.

    Micheli, Giulia / Sangiorgi, Flavio / Catania, Francesca / Chiuchiarelli, Marta / Frondizi, Federico / Taddei, Eleonora / Murri, Rita

    Microorganisms

    2023  Volume 11, Issue 5

    Abstract: Antibiotic resistance is one of the greatest growing public health threats and a worldwide priority. According to the WHO, drug-resistant diseases may cause 10 million deaths a year by 2050 and have a substantial impact on the global economy, driving up ... ...

    Abstract Antibiotic resistance is one of the greatest growing public health threats and a worldwide priority. According to the WHO, drug-resistant diseases may cause 10 million deaths a year by 2050 and have a substantial impact on the global economy, driving up to 24 million people into poverty. The ongoing COVID-19 pandemic has exposed the fallacies and vulnerability of healthcare systems worldwide, displacing resources from existing programs and reducing funding for antimicrobial resistance (AMR) fighting efforts. Moreover, as already seen for other respiratory viruses, such as flu, COVID-19 is often associated with superinfections, prolonged hospital stays, and increased ICU admissions, further aggravating healthcare disruption. These events are accompanied by widespread antibiotic use, misuse, and inappropriate compliance with standard procedures with a potential long-term impact on AMR. Still, COVID-19-related measures such as increasing personal and environmental hygiene, social distancing, and decreasing hospital admissions could theoretically help the AMR cause. However, several reports have shown increased antimicrobial resistance during the COVID-19 pandemic. This narrative review focuses on this "twindemic", assessing the current knowledge of antimicrobial resistance in the COVID-19 era with a focus on bloodstream infections and provides insights into the lessons learned in the COVID-19 field that could be applied to antimicrobial stewardship initiatives.
    Language English
    Publishing date 2023-05-16
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms11051299
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Complications associated with the use of peripherally inserted central catheters and midline catheters in COVID-19 patients: An observational prospective study.

    Frondizi, Federico / Dolcetti, Laura / Pittiruti, Mauro / Calabrese, Maria / Fantoni, Massimo / Biasucci, Daniele Guerino / Scoppettuolo, Giancarlo

    American journal of infection control

    2023  

    Abstract: Background: Among the many interesting aspects of clinical care during the SARS-CoV-2 pandemic, vascular access still deserves some attention. Peripherally inserted central catheters (PICCs) and midline catheters (MCs) are venous access devices inserted ...

    Abstract Background: Among the many interesting aspects of clinical care during the SARS-CoV-2 pandemic, vascular access still deserves some attention. Peripherally inserted central catheters (PICCs) and midline catheters (MCs) are venous access devices inserted by ultrasound-guided puncture of veins of the arm, which have been associated with the possibility of minimizing infectious complications in different populations of patients. We have investigated their performance in SARS-CoV-2 patients.
    Methods: As the incidence of catheter-related bloodstream infections (CRBSI) in patients hospitalized for COVID-19 is still unclear, we have designed a single-center, prospective observational study enrolling all patients with established diagnosis of SARS-CoV-2 infection who were admitted to our hospital in the period between October 2020 and April 2021 and who required either a PICC or a MC.
    Results: We recruited 227 patients. The cumulative incidence of CRBSI was 4.35% (10 cases), that is, 3.5 episodes/1,000 catheter days. Four CRBSI occurred in patients with PICCs (4.5/1,000 catheter days) and 6 in those with MCs (3.2/1,000 catheter days).
    Conclusions: Our data suggest that COVID-19 patients may have a more pronounced tendency for the development of catheter-related infections compared to other populations of patients.
    Language English
    Publishing date 2023-05-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 392362-9
    ISSN 1527-3296 ; 0196-6553
    ISSN (online) 1527-3296
    ISSN 0196-6553
    DOI 10.1016/j.ajic.2023.05.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Cutaneous diphtheria most likely due to exposure in a detention camp in Libya.

    Taccari, Francesco / Frondizi, Federico / Salvati, Federica / Giovannenze, Francesca / Del Giacomo, Paola / Damiano, Fernando / Spanu, Teresa / Graffeo, Rosalia / Menchinelli, Giulia / Mariotti, Melinda / Sanguinetti, Maurizio / Castri, Federica / Neumayr, Andreas / Brunetti, Enrico / Errico, Giulia / Murri, Rita / Cauda, Roberto / Scoppettuolo, Giancarlo

    Journal of travel medicine

    2023  Volume 30, Issue 5

    MeSH term(s) Humans ; Diphtheria ; Libya ; Corynebacterium diphtheriae ; Diphtheria Toxin
    Chemical Substances Diphtheria Toxin
    Language English
    Publishing date 2023-05-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 1212504-0
    ISSN 1708-8305 ; 1195-1982
    ISSN (online) 1708-8305
    ISSN 1195-1982
    DOI 10.1093/jtm/taad073
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: Impact of SARS-CoV-2 vaccination and passive prophylaxis with tixagevimab/cilgavimab on CAR-T patients: a three-year regional experience from the Italian covid pandemic.

    Galli, Eugenio / Di Rocco, Alice / Pansini, Ilaria / Frondizi, Federico / Di Palma, Martina / Metafuni, Elisabetta / Piccirillo, Nicola / Bianchi, Maria / Cingolani, Antonella / Torelli, Giovanni Fernando / Hohaus, Stefan / Chiusolo, Patrizia / Iori, Anna Paola / Sica, Simona / Martelli, Maurizio / Sorà, Federica

    Bone marrow transplantation

    2023  Volume 58, Issue 12, Page(s) 1394–1396

    MeSH term(s) Humans ; Pandemics/prevention & control ; COVID-19 Vaccines ; Receptors, Chimeric Antigen ; SARS-CoV-2 ; COVID-19/prevention & control ; Vaccination
    Chemical Substances tixagevimab ; cilgavimab (1KUR4BN70F) ; COVID-19 Vaccines ; Receptors, Chimeric Antigen
    Language English
    Publishing date 2023-09-04
    Publishing country England
    Document type Letter
    ZDB-ID 632854-4
    ISSN 1476-5365 ; 0268-3369 ; 0951-3078
    ISSN (online) 1476-5365
    ISSN 0268-3369 ; 0951-3078
    DOI 10.1038/s41409-023-02093-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top