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  1. Book ; Online ; E-Book: Movement disorder emergencies

    Frucht, Steven J.

    diagnosis and treatment

    (Current Clinical Neurology)

    2022  

    Author's details Steven J. Frucht, editor
    Series title Current Clinical Neurology
    MeSH term(s) Movement Disorders/diagnosis. ; Emergencies. ; Movement Disorders/therapy. ; Diagnosis, Differential.
    Keywords Movement disorders ; Movement disorders/Diagnosis
    Subject code 616.83
    Language English
    Dates of publication 2022-2022
    Size 1 online resource (602 pages) :, illustrations.
    Edition Third edition.
    Publisher Humana Press
    Publishing place Cham, Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 3-030-75898-2 ; 3-030-75897-4 ; 978-3-030-75898-1 ; 978-3-030-75897-4
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book: Movement Disorder Emergencies

    Frucht, Steven J.

    Diagnosis and Treatment

    (Current Clinical Neurology)

    2021  

    Author's details Steven J. Frucht, MD Department of NeurologyNYU Langone Health New York, NY USA § § §
    Series title Current Clinical Neurology
    Keywords Movement Disorders ; emergency ; Parkinson¿s ; Dystonia ; chorea ; Tremor ; Myoclonus ; Movement disorders ; Emergency ; Parkinson’s ; Chorea
    Language English
    Size 632 p.
    Edition 3
    Publisher Springer International Publishing
    Document type Book
    Note PDA Manuell_11
    Format 160 x 241 x 37
    ISBN 9783030758974 ; 3030758974
    Database PDA

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  3. Book ; Online ; E-Book: Movement Disorders Phenomenology

    Frucht, Steven J. / Termsarasab, Pichet

    An Office-Based Approach

    2020  

    Abstract: This book presents a comprehensive, practical approach to the evaluation of movement disorders using phenomenological basic principles, new discoveries in phenomenological research, and core values of outpatient neurology. Movement Disorders ... ...

    Author's details by Steven J. Frucht, Pichet Termsarasab
    Abstract This book presents a comprehensive, practical approach to the evaluation of movement disorders using phenomenological basic principles, new discoveries in phenomenological research, and core values of outpatient neurology. Movement Disorders Phenomenology begins with an overview of phenomenology and common approaches to movement disorder patients. Subsequent chapters then accurately and concisely relay information on major hypokinetic disorders such as atypical Parkinsonism, idiopathic Parkinson’s disease, cortical myoclonus, and complex motor tics. Expertly written text is further supplemented by patient vignettes at the beginning of select chapter that focus the reader's attention and highlight the urgency of the problem. These high quality videos aid in the astute clinical diagnosis of many movement disorders that are still largely dependent on visual pattern recognition in the clinic. The book closes with a timely discussion on the role of genetics in movement disorders. Written for the practicing physician, Movement Disorders Phenomenology is an indispensable reference for neurology residents, general neurologists, movement disorders fellows and clinicians, and to any clinician who encounters and evaluates patients in the outpatient arena.
    Keywords Neurology  ; Neurology
    Subject code 616.83
    Language English
    Size 1 online resource (XV, 314 p. 57 illus., 34 illus. in color.)
    Edition 1st ed. 2020.
    Publisher Springer International Publishing ; Imprint: Springer
    Publishing place Cham
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 3-030-36975-7 ; 3-030-36974-9 ; 978-3-030-36975-0 ; 978-3-030-36974-3
    DOI 10.1007/978-3-030-36975-0
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Book: Movement disorder emergencies

    Frucht, Steven J.

    diagnosis and treatment

    (Current clinical neurology)

    2013  

    Author's details ed. by Steven J. Frucht
    Series title Current clinical neurology
    Keywords Movement Disorders / diagnosis ; Emergencies ; Movement Disorders / therapy
    Language English
    Size XVIII, 401 S. : Ill.
    Edition 2. ed.
    Publisher Humana Press
    Publishing place New York u.a.
    Publishing country United States
    Document type Book
    Accompanying material 1 DVD-ROM (12 cm)
    HBZ-ID HT017582119
    ISBN 978-1-60761-834-8 ; 9781607618355 ; 1-60761-834-6 ; 1607618354
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2013 A 70 available for loan (reading room) Lesesaal EG
    2013 MO 171 <<[Begleitmaterial]>> order for loan Magazin

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  5. Article ; Online: Effect of Urate-Elevating Inosine on Progression of Early Parkinson Disease.

    Frucht, Steven J

    JAMA

    2022  Volume 327, Issue 1, Page(s) 85

    MeSH term(s) Disease Progression ; Humans ; Inosine ; Parkinson Disease/drug therapy ; Uric Acid
    Chemical Substances Uric Acid (268B43MJ25) ; Inosine (5A614L51CT)
    Language English
    Publishing date 2022-01-04
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2958-0
    ISSN 1538-3598 ; 0254-9077 ; 0002-9955 ; 0098-7484
    ISSN (online) 1538-3598
    ISSN 0254-9077 ; 0002-9955 ; 0098-7484
    DOI 10.1001/jama.2021.21008
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  6. Book: Movement disorder emergencies

    Frucht, Steven J.

    diagnosis and treatment

    (Current clinical neurology)

    2005  

    Author's details ed. by Steven J. Frucht
    Series title Current clinical neurology
    Keywords Movement Disorders / diagnosis ; Emergencies ; Movement Disorders / therapy
    Language English
    Size XIV, 250 S. : Ill.
    Publisher Humana Press
    Publishing place Totowa, NJ
    Publishing country United States
    Document type Book
    Note Systemvoraussetzungen: Compatible with Windows and Apple Macintosh operating systems
    Accompanying material 1 DVD-ROM (12 cm)
    HBZ-ID HT013950621
    ISBN 1-58829-305-X ; 978-1-58829-305-3
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2006 A 5591 order for loan Magazin
    2006 MO 1058 <<[Begleitmaterial>>] order for loan Magazin

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  7. Article ; Online: Is essential tremor a family of diseases or a syndrome? A family of diseases.

    Riboldi, Giulietta M / Frucht, Steven J

    International review of neurobiology

    2022  Volume 163, Page(s) 7–29

    Abstract: It is now well-established that essential tremor (ET) can manifest with different clinical presentations and progressions (i.e., upper limb tremor, head tremor, voice tremor, lower limb tremor, task- or position-specific tremor, or a combination of those) ...

    Abstract It is now well-established that essential tremor (ET) can manifest with different clinical presentations and progressions (i.e., upper limb tremor, head tremor, voice tremor, lower limb tremor, task- or position-specific tremor, or a combination of those). Common traits and overlaps are identifiable across these different subtypes of ET, including a slow rate of progression, a response to alcohol and a positive family history. At the same time, each of these manifestations are associated with specific demographic, clinical and treatment-response characteristics suggesting a family of diseases rather than a spectrum of a syndrome. Here we summarize the most important clinical, demographic, neuropathological and imagingfeatures of ET and of its subtypes to support ET as a family of identifiable conditions. This classification has relevance for counseling of patients with regard to disease progression and treatment response, as well as for the design of therapeutic clinical trials.
    MeSH term(s) Essential Tremor/diagnosis ; Essential Tremor/therapy ; Humans ; Syndrome ; Tremor
    Language English
    Publishing date 2022-03-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 209876-3
    ISSN 2162-5514 ; 0074-7742
    ISSN (online) 2162-5514
    ISSN 0074-7742
    DOI 10.1016/bs.irn.2022.02.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Billiards-related dystonia: A new task-specific dystonia.

    Frucht, Steven J

    Parkinsonism & related disorders

    2019  Volume 60, Page(s) 12–13

    MeSH term(s) Dystonia ; Dystonic Disorders ; Humans
    Language English
    Publishing date 2019-02-21
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 1311489-x
    ISSN 1873-5126 ; 1353-8020
    ISSN (online) 1873-5126
    ISSN 1353-8020
    DOI 10.1016/j.parkreldis.2019.02.023
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  9. Article: Isolated and combined dystonias: Update.

    Bukhari-Parlakturk, Noreen / Frucht, Steven J

    Handbook of clinical neurology

    2023  Volume 196, Page(s) 425–442

    Abstract: Dystonia is a hyperkinetic movement disorder with a unique motor phenomenology that can manifest as an isolated clinical syndrome or combined with other neurological features. This chapter reviews the characteristic features of dystonia phenomenology and ...

    Abstract Dystonia is a hyperkinetic movement disorder with a unique motor phenomenology that can manifest as an isolated clinical syndrome or combined with other neurological features. This chapter reviews the characteristic features of dystonia phenomenology and the syndromic approach to evaluating the disorders that may allow us to differentiate the isolated and combined syndromes. We also present the most common types of isolated and combined dystonia syndromes. Since accelerated gene discoveries have increased our understanding of the molecular mechanisms of dystonia pathogenesis, we also present isolated and combined dystonia syndromes by shared biological pathways. Examples of these converging mechanisms of the isolated and combined dystonia syndromes include (1) disruption of the integrated response pathway through eukaryotic initiation factor 2 alpha signaling, (2) disease of dopaminergic signaling, (3) alterations in the cerebello-thalamic pathway, and (4) disease of protein mislocalization and stability. The discoveries that isolated and combined dystonia syndromes converge in shared biological pathways will aid in the development of clinical trials and therapeutic strategies targeting these convergent molecular pathways.
    MeSH term(s) Humans ; Dystonia ; Syndrome ; Dystonic Disorders/genetics ; Cerebellum ; Dopamine
    Chemical Substances Dopamine (VTD58H1Z2X)
    Language English
    Publishing date 2023-07-14
    Publishing country Netherlands
    Document type Review ; Journal Article
    ISSN 0072-9752
    ISSN 0072-9752
    DOI 10.1016/B978-0-323-98817-9.00005-3
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  10. Article ; Online: Sodium Oxybate in Alcohol-Responsive Essential Tremor of Voice: An Open-Label Phase II Study.

    O'Flynn, Lena C / Frucht, Steven J / Simonyan, Kristina

    Movement disorders : official journal of the Movement Disorder Society

    2023  Volume 38, Issue 10, Page(s) 1936–1944

    Abstract: Background: Essential tremor of voice (ETv) is characterized by involuntary oscillations of laryngeal and upper airway muscles, causing rhythmic alterations in pitch and loudness during both passive breathing and active laryngeal tasks, such as speaking ...

    Abstract Background: Essential tremor of voice (ETv) is characterized by involuntary oscillations of laryngeal and upper airway muscles, causing rhythmic alterations in pitch and loudness during both passive breathing and active laryngeal tasks, such as speaking and singing. Treatment of ETv is challenging and typically less effective compared with treatment of ET affecting extremities.
    Objective: We conducted a proof-of-concept, open-label phase II study to examine the efficacy and central effects of sodium oxybate in patients with alcohol-responsive ETv.
    Methods: All subjects received 1.0 to 1.5 g of oral sodium oxybate and underwent brain functional magnetic resonance imaging. The primary endpoint was the number of patients (% from total) with reduced ETv symptoms by at least 10% at about 40 to 45 minutes after sodium oxybate intake based on the combined visual analog scale score of ETv symptom severity. The secondary endpoint included changes in brain activity after sodium oxybate intake compared to baseline.
    Results: Sodium oxybate reduced ETv symptoms on average by 40.8% in 92.9% of patients. Drug effects were observed about 40 to 45 minutes after intake, lasting about 3.5 hours, and gradually wearing off by the end of the fifth hour. The central effects of sodium oxybate were associated with normalized activity in the cerebellum, inferior/superior parietal lobules, inferior frontal gyrus, and insula and re-established functional relationships between these regions.
    Conclusions: Sodium oxybate showed high efficacy in ETv patients, with a likely central action on disorder pathophysiology. Sodium oxybate may be an effective novel oral drug for treatment of alcohol-responsive ETv patients. © 2023 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
    MeSH term(s) Humans ; Sodium Oxybate/adverse effects ; Essential Tremor/drug therapy ; Ethanol ; Treatment Outcome
    Chemical Substances Sodium Oxybate (7G33012534) ; Ethanol (3K9958V90M)
    Language English
    Publishing date 2023-07-14
    Publishing country United States
    Document type Clinical Trial, Phase II ; Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 607633-6
    ISSN 1531-8257 ; 0885-3185
    ISSN (online) 1531-8257
    ISSN 0885-3185
    DOI 10.1002/mds.29529
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