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Article ; Online: C. acnes

Zhang, Jingheng / Yu, Fang / Fu, Keyun / Ma, Xinyu / Han, Yi / Ali, Chi Ching / Zhou, Haonan / Xu, Yantao / Zhang, Tingyue / Kang, Shuntong / Xu, Yiming / Li, Zhuolin / Shi, Jiaqi / Gao, Shuai / Chen, Yongyi / Chen, Liyu / Zhang, Jianglin / Zhu, Feizhou

Frontiers in public health

2022 Volume 10, Page(s) 787299

Abstract: Background: Macrolides have been widely used to treat moderate-to-severe acne for more than 50 years. However, the prevalent antibiotic resistance of Propionibacterium acnes, along with the absence of clinically available resistance tests, has made ... ...

Abstract	Background: Macrolides have been widely used to treat moderate-to-severe acne for more than 50 years. However, the prevalent antibiotic resistance of Propionibacterium acnes, along with the absence of clinically available resistance tests, has made macrolide misuse a frequent occurrence around the globe, with serious consequences. Objective: We developed Methods: A cross-sectional observational study ( Results: The high sensitivity of ACQUIRE enabled us to reveal a much higher Conclusion: The macrolide resistance of
MeSH term(s)	Acne Vulgaris/drug therapy ; Acne Vulgaris/microbiology ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Cross-Sectional Studies ; Drug Resistance, Bacterial/genetics ; Humans ; Macrolides/pharmacology ; Macrolides/therapeutic use ; Microbial Sensitivity Tests
Chemical Substances	Anti-Bacterial Agents ; Macrolides
Language	English
Publishing date	2022-03-18
Publishing country	Switzerland
Document type	Journal Article ; Observational Study ; Research Support, Non-U.S. Gov't
ZDB-ID	2711781-9
ISSN	2296-2565 ; 2296-2565
ISSN (online)	2296-2565
ISSN	2296-2565
DOI	10.3389/fpubh.2022.787299
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Original Hosts, Clinical Features, Transmission Routes, and Vaccine Development for Coronavirus Disease (COVID-19).

Wu, Ting / Kang, Shuntong / Peng, Wenyao / Zuo, Chenzhe / Zhu, Yuhao / Pan, Liangyu / Fu, Keyun / You, Yaxian / Yang, Xinyuan / Luo, Xuan / Jiang, Liping / Deng, Meichun

Frontiers in medicine

2021 Volume 8, Page(s) 702066

Abstract: The pandemic of coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to public concern worldwide. Although a variety of hypotheses about the hosts of SARS-CoV-2 have been proposed, ... ...

Abstract	The pandemic of coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to public concern worldwide. Although a variety of hypotheses about the hosts of SARS-CoV-2 have been proposed, an exact conclusion has not yet been reached. Initial clinical manifestations associated with COVID-19 are similar to those of other acute respiratory infections, leading to misdiagnoses and resulting in the outbreak at the early stage. SARS-CoV-2 is predominantly spread by droplet transmission and close contact; the possibilities of fecal-oral, vertical, and aerosol transmission have not yet been fully confirmed or rejected. Besides, COVID-19 cases have been reported within communities, households, and nosocomial settings through contact with confirmed COVID-19 patients or asymptomatic individuals. Environmental contamination is also a major driver for the COVID-19 pandemic. Considering the absence of specific treatment for COVID-19, it is urgent to decrease the risk of transmission and take preventive measures to control the spread of the virus. In this review, we summarize the latest available data on the potential hosts, entry receptors, clinical features, and risk factors of COVID-19 and transmission routes of SARS-CoV-2, and we present the data about development of vaccines.
Language	English
Publishing date	2021-07-06
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2775999-4
ISSN	2296-858X
ISSN	2296-858X
DOI	10.3389/fmed.2021.702066
Database	MEDical Literature Analysis and Retrieval System OnLINE