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  1. Thesis ; Online: Empowering Diet-Related Health Behavior Change Interventions via Digital Receipts and Food Composition Databases

    Fuchs, Klaus Ludwig

    2020  

    Keywords info:eu-repo/classification/ddc/610 ; info:eu-repo/classification/ddc/600 ; Medical sciences ; medicine ; Technology (applied sciences)
    Language English
    Publisher ETH Zurich
    Publishing country ch
    Document type Thesis ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: The Effect of a Future-Self Avatar Mobile Health Intervention (FutureMe) on Physical Activity and Food Purchases: Randomized Controlled Trial.

    Mönninghoff, Annette / Fuchs, Klaus / Wu, Jing / Albert, Jan / Mayer, Simon

    Journal of medical Internet research

    2022  Volume 24, Issue 7, Page(s) e32487

    Abstract: Background: Insufficient physical activity and unhealthy diets are contributing to the rise in noncommunicable diseases. Preventative mobile health (mHealth) interventions may help reverse this trend, but present bias might reduce their effectiveness. ... ...

    Abstract Background: Insufficient physical activity and unhealthy diets are contributing to the rise in noncommunicable diseases. Preventative mobile health (mHealth) interventions may help reverse this trend, but present bias might reduce their effectiveness. Future-self avatar interventions have resulted in behavior change in related fields, yet evidence of whether such interventions can change health behavior is lacking.
    Objective: We aimed to investigate the impact of a future-self avatar mHealth intervention on physical activity and food purchasing behavior and examine the feasibility of a novel automated nutrition tracking system. We also aimed to understand how this intervention impacts related attitudinal and motivational constructs.
    Methods: We conducted a 12-week parallel randomized controlled trial (RCT), followed by semistructured interviews. German-speaking smartphone users aged ≥18 years living in Switzerland and using at least one of the two leading Swiss grocery loyalty cards, were recruited for the trial. Data were collected from November 2020 to April 2021. The intervention group received the FutureMe intervention, a physical activity and food purchase tracking mobile phone app that uses a future-self avatar as the primary interface and provides participants with personalized food basket analysis and shopping tips. The control group received a conventional text- and graphic-based primary interface intervention. We pioneered a novel system to track nutrition by leveraging digital receipts from loyalty card data and analyzing food purchases in a fully automated way. Data were consolidated in 4-week intervals, and nonparametric tests were conducted to test for within- and between-group differences.
    Results: We recruited 167 participants, and 95 eligible participants were randomized into either the intervention (n=42) or control group (n=53). The median age was 44 years (IQR 19), and the gender ratio was balanced (female 52/95, 55%). Attrition was unexpectedly high with only 30 participants completing the intervention, negatively impacting the statistical power. The FutureMe intervention led to small statistically insignificant increases in physical activity (median +242 steps/day) and small insignificant improvements in the nutritional quality of food purchases (median -1.28 British Food Standards Agency Nutrient Profiling System Dietary Index points) at the end of the intervention. Intrinsic motivation significantly increased (P=.03) in the FutureMe group, but decreased in the control group. Outcome expectancy directionally increased in the FutureMe group, but decreased in the control group. Leveraging loyalty card data to track the nutritional quality of food purchases was found to be a feasible and accepted fully automated nutrition tracking system.
    Conclusions: Preventative future-self avatar mHealth interventions promise to encourage improvements in physical activity and food purchasing behavior in healthy population groups. A full-powered RCT is needed to confirm this preliminary evidence and to investigate how future-self avatars might be modified to reduce attrition, overcome present bias, and promote sustainable behavior change.
    Trial registration: ClinicalTrials.gov NCT04505124; https://clinicaltrials.gov/ct2/show/NCT04505124.
    MeSH term(s) Adolescent ; Adult ; Cell Phone ; Exercise ; Female ; Health Behavior ; Humans ; Mobile Applications ; Telemedicine/methods
    Language English
    Publishing date 2022-07-07
    Publishing country Canada
    Document type Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
    ZDB-ID 2028830-X
    ISSN 1438-8871 ; 1439-4456
    ISSN (online) 1438-8871
    ISSN 1439-4456
    DOI 10.2196/32487
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Effects of Digital Food Labels on Healthy Food Choices in Online Grocery Shopping.

    Fuchs, Klaus L / Lian, Jie / Michels, Leonard / Mayer, Simon / Toniato, Enrico / Tiefenbeck, Verena

    Nutrients

    2022  Volume 14, Issue 10

    Abstract: In order to induce the shift in consumer behavior necessary for the mitigation of diet-related diseases, front-of-package labels (FoPL) such as the Nutri-Score that support consumers in their efforts to identify nutritionally valuable products during ... ...

    Abstract In order to induce the shift in consumer behavior necessary for the mitigation of diet-related diseases, front-of-package labels (FoPL) such as the Nutri-Score that support consumers in their efforts to identify nutritionally valuable products during grocery shopping have been found to be effective; however, they remain non-compulsory in most regions. Counter-intuitively, a similar stream of research on digital web-based FoPL does not yet exist, even though such digital labels hold several advantages over physical labels. Digital FoPL can provide scalable and personalized interventions, are easier to implement than physical labels, and are especially timely due to the recent increase in online grocery shopping. The goal of this study was to demonstrate the technical feasibility and intervention potential of novel, scalable, and passively triggered health behavior interventions distributed via easy-to-install web browser extensions designed to support healthy food choices via the inclusion of digital FoPL in online supermarkets. To that end, we developed a Chrome web browser extension for a real online supermarket and evaluated the effect of this digital food label intervention (i.e., display of the Nutri-Score next to visible products) on the nutritional quality of individuals' weekly grocery shopping in a randomized controlled laboratory trial (
    MeSH term(s) Choice Behavior ; Consumer Behavior ; Food Labeling ; Food Preferences ; Humans ; Sugars
    Chemical Substances Sugars
    Language English
    Publishing date 2022-05-13
    Publishing country Switzerland
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu14102044
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book ; Thesis: Iatrogene Strikturen

    Fuchs, Klaus

    1983  

    Size 252 Bl. : Ill., graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis München, Techn. Univ., Diss., 1983
    HBZ-ID HT003124372
    Database Catalogue ZB MED Medicine, Health

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  5. Article: Buy three to waste one? How real-world purchase data predict groups of food wasters

    Merian, Sybilla / Stöeckli, Sabrina / Fuchs, Klaus Ludwig / Natter, Martin

    Sustainability

    2022  Volume 14, Issue 16, Page(s) No

    Abstract: Approximately one-third of all food produced for human consumption is either lost or wasted. Given the central position of retailers in the supply chain, they have the potential to effectively reduce consumer food waste by implementing targeted ... ...

    Title translation Drei kaufen, um einen zu verschwenden? Wie reale Kaufdaten Gruppen von Lebensmittelverschwendern vorhersagen
    Abstract Approximately one-third of all food produced for human consumption is either lost or wasted. Given the central position of retailers in the supply chain, they have the potential to effectively reduce consumer food waste by implementing targeted interventions. To do so, however, they should target distinct consumer groups. In this research, we use a unique data set comprising the grocery shopping data of customers who use loyalty cards, complemented with food waste reports, to derive three distinct target groups: traditionals, time-constrained, and convenience lovers. Based on the general behavioral change literature, we discuss diverse target group-specific interventions that retailers can implement to reduce consumer food waste. Overall, we pave a research path to examine how retailers and marketing can effectively shift consumer behavior toward more sustainable food and shopping practices and assume responsibility within the food supply chain.
    Keywords Conservation (Ecological Behavior) ; Consumer Behavior ; Einkaufen ; Einzelhandel ; Food ; Intervention ; Konsumverhalten ; Marketing ; Nahrungsmittel ; Responsibility ; Retailing ; Shopping ; Umweltschutzverhalten ; Verantwortlichkeit
    Language English
    Document type Article
    DOI 10.3390/su141610183
    Database PSYNDEX

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  6. Article: Estimating Dietary Intake from Grocery Shopping Data—A Comparative Validation of Relevant Indicators in Switzerland

    Wu, Jing / Fuchs, Klaus / Lian, Jie / Haldimann, Mirella Lindsay / Schneider, Tanja / Mayer, Simon / Byun, Jaewook / Gassmann, Roland / Brombach, Christine / Fleisch, Elgar

    Nutrients. 2021 Dec. 29, v. 14, no. 1

    2021  

    Abstract: In light of the globally increasing prevalence of diet-related chronic diseases, new scalable and non-invasive dietary monitoring techniques are urgently needed. Automatically collected digital receipts from loyalty cards hereby promise to serve as an ... ...

    Abstract In light of the globally increasing prevalence of diet-related chronic diseases, new scalable and non-invasive dietary monitoring techniques are urgently needed. Automatically collected digital receipts from loyalty cards hereby promise to serve as an objective and automatically traceable digital marker for individual food choice behavior and do not require users to manually log individual meal items. With the introduction of the General Data Privacy Regulation in the European Union, millions of consumers gained the right to access their shopping data in a machine-readable form, representing a historic chance to leverage shopping data for scalable monitoring of food choices. Multiple quantitative indicators for evaluating the nutritional quality of food shopping have been suggested, but so far, no comparison has validated the potential of these alternative indicators within a comparative setting. This manuscript thus represents the first study to compare the calibration capacity and to validate the discrimination potential of previously suggested food shopping quality indicators for the nutritional quality of shopped groceries, including the Food Standards Agency Nutrient Profiling System Dietary Index (FSA-NPS DI), Grocery Purchase Quality Index-2016 (GPQI), Healthy Eating Index-2015 (HEI-2015), Healthy Trolley Index (HETI) and Healthy Purchase Index (HPI), checking if any of them performs differently from the others. The hypothesis is that some food shopping quality indicators outperform the others in calibrating and discriminating individual actual dietary intake. To assess the indicators’ potentials, 89 eligible participants completed a validated food frequency questionnaire (FFQ) and donated their digital receipts from the loyalty card programs of the two leading Swiss grocery retailers, which represent 70% of the national grocery market. Compared to absolute food and nutrient intake, correlations between density-based relative food and nutrient intake and food shopping data are stronger. The FSA-NPS DI has the best calibration and discrimination performance in classifying participants’ consumption of nutrients and food groups, and seems to be a superior indicator to estimate nutritional quality of a user’s diet based on digital receipts from grocery shopping in Switzerland.
    Keywords European Union ; calibration ; food choices ; food frequency questionnaires ; food intake ; markets ; nutrient intake ; nutritive value ; Switzerland
    Language English
    Dates of publication 2021-1229
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    ZDB-ID 2518386-2
    ISSN 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu14010159
    Database NAL-Catalogue (AGRICOLA)

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  7. Article ; Online: LY6G6D is a selectively expressed colorectal cancer antigen that can be used for targeting a therapeutic T-cell response by a T-cell engager.

    Corrales, Leticia / Hipp, Susanne / Martin, Katharina / Sabarth, Nicolas / Tirapu, Iñigo / Fuchs, Klaus / Thaler, Barbara / Walterskirchen, Christian / Bauer, Kathrin / Fabits, Markus / Bergmann, Michael / Binder, Carina / Chetta, Paolo Ml / Vogt, Anne B / Adam, Paul J

    Frontiers in immunology

    2022  Volume 13, Page(s) 1008764

    Abstract: Colorectal cancer (CRC) is one of the most common cancers worldwide and demands more effective treatments. We sought to identify tumor selective CRC antigens and their therapeutic potential for cytotoxic T-cell targeting by transcriptomic and ... ...

    Abstract Colorectal cancer (CRC) is one of the most common cancers worldwide and demands more effective treatments. We sought to identify tumor selective CRC antigens and their therapeutic potential for cytotoxic T-cell targeting by transcriptomic and immunohistochemical analysis. LY6G6D was identified as a tumor selectively expressed CRC antigen, mainly in the microsatellite stable (MSS) subtype. A specific anti LY6G6D/CD3 T cell engager (TcE) was generated and demonstrated potent tumor cell killing and T cell activation
    MeSH term(s) Animals ; Antigens, Neoplasm ; Colorectal Neoplasms ; Humans ; Immunoglobulins ; Lymphocyte Activation ; Mice ; T-Lymphocytes, Cytotoxic ; Tumor Necrosis Factor-alpha
    Chemical Substances Antigens, Neoplasm ; Immunoglobulins ; LY6G6D protein, human ; Tumor Necrosis Factor-alpha
    Language English
    Publishing date 2022-09-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2022.1008764
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Digital Solutions to Diagnose and Manage Postbariatric Hypoglycemia.

    Schönenberger, Katja A / Cossu, Luca / Prendin, Francesco / Cappon, Giacomo / Wu, Jing / Fuchs, Klaus L / Mayer, Simon / Herzig, David / Facchinetti, Andrea / Bally, Lia

    Frontiers in nutrition

    2022  Volume 9, Page(s) 855223

    Abstract: Postbariatric hypoglycemia (PBH) is an increasingly recognized late metabolic complication of bariatric surgery, characterized by low blood glucose levels 1-3 h after a meal, particularly if the meal contains rapid-acting carbohydrates. PBH can often be ... ...

    Abstract Postbariatric hypoglycemia (PBH) is an increasingly recognized late metabolic complication of bariatric surgery, characterized by low blood glucose levels 1-3 h after a meal, particularly if the meal contains rapid-acting carbohydrates. PBH can often be effectively managed through appropriate nutritional measures, which remain the cornerstone treatment today. However, their implementation in daily life continues to challenge both patients and health care providers. Emerging digital technologies may allow for more informed and improved decision-making through better access to relevant data to manage glucose levels in PBH. Examples include applications for automated food analysis from meal images, digital receipts of purchased food items or integrated platforms allowing the connection of continuously measured glucose with food and other health-related data. The resulting multi-dimensional data can be processed with artificial intelligence systems to develop prediction algorithms and decision support systems with the aim of improving glucose control, safety, and quality of life of PBH patients. Digital innovations, however, face trade-offs between user burden vs. amount and quality of data. Further challenges to their development are regulatory non-compliance regarding data ownership of the platforms acquiring the required data, as well as user privacy concerns and compliance with regulatory requirements. Through navigating these trade-offs, digital solutions could significantly contribute to improving the management of PBH.
    Language English
    Publishing date 2022-04-07
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2776676-7
    ISSN 2296-861X
    ISSN 2296-861X
    DOI 10.3389/fnut.2022.855223
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: The Effect of a Future-Self Avatar Mobile Health Intervention (FutureMe) on Physical Activity and Food Purchases

    Mönninghoff, Annette / Fuchs, Klaus Ludwig / id_orcid:0 000-0003-3226-920X / Wu, Jing / Albert, Jan / Mayer, Simon

    Journal of Medical Internet Research, 24 (7)

    Randomized Controlled Trial

    2022  

    Abstract: Background: Insufficient physical activity and unhealthy diets are contributing to the rise in noncommunicable diseases. Preventative mobile health (mHealth) interventions may help reverse this trend, but present bias might reduce their effectiveness. ... ...

    Abstract Background: Insufficient physical activity and unhealthy diets are contributing to the rise in noncommunicable diseases. Preventative mobile health (mHealth) interventions may help reverse this trend, but present bias might reduce their effectiveness. Future-self avatar interventions have resulted in behavior change in related fields, yet evidence of whether such interventions can change health behavior is lacking. Objective: We aimed to investigate the impact of a future-self avatar mHealth intervention on physical activity and food purchasing behavior and examine the feasibility of a novel automated nutrition tracking system. We also aimed to understand how this intervention impacts related attitudinal and motivational constructs. Methods: We conducted a 12-week parallel randomized controlled trial (RCT), followed by semistructured interviews. German-speaking smartphone users aged ≥18 years living in Switzerland and using at least one of the two leading Swiss grocery loyalty cards, were recruited for the trial. Data were collected from November 2020 to April 2021. The intervention group received the FutureMe intervention, a physical activity and food purchase tracking mobile phone app that uses a future-self avatar as the primary interface and provides participants with personalized food basket analysis and shopping tips. The control group received a conventional text- and graphic-based primary interface intervention. We pioneered a novel system to track nutrition by leveraging digital receipts from loyalty card data and analyzing food purchases in a fully automated way. Data were consolidated in 4-week intervals, and nonparametric tests were conducted to test for within- and between-group differences. Results: We recruited 167 participants, and 95 eligible participants were randomized into either the intervention (n=42) or control group (n=53). The median age was 44 years (IQR 19), and the gender ratio was balanced (female 52/95, 55%). Attrition was unexpectedly high with only 30 participants completing the ...
    Keywords mHealth ; mobile health ; preventative medicine ; avatar ; present bias ; nutrition tracking ; physical activity ; randomized controlled trial
    Subject code 796
    Language English
    Publisher JMIR Publications
    Publishing country ch
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Conference proceedings ; Online: Towards Interoperability in Mobile Coupons

    Fuchs, Klaus L. / Vuckovac, Denis / Ilic, Alexander

    ICT Convergence Technologies Leading the Fourth Industrial Revolution. International Conference on ICT Convergence 2017 (ICTC 2017)

    Enabling Cross Retailer Coupon Validation

    2017  

    Keywords Interoperability ; Interface Specifications ; Retailing ; System architecture ; info:eu-repo/classification/ddc/000 ; Generalities ; science
    Language English
    Publisher IEEE
    Publishing country ch
    Document type Conference proceedings ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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