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  1. Article ; Online: A Combination of Autoantibodies Predicts the Fate of Cancer-Associated Dermatomyositis.

    Fujimoto, Manabu

    Arthritis & rheumatology (Hoboken, N.J.)

    2023  Volume 75, Issue 7, Page(s) 1085–1087

    MeSH term(s) Humans ; Dermatomyositis/complications ; Autoantibodies ; Interferon-Induced Helicase, IFIH1 ; Neoplasms
    Chemical Substances Autoantibodies ; Interferon-Induced Helicase, IFIH1 (EC 3.6.4.13)
    Language English
    Publishing date 2023-05-10
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2756371-6
    ISSN 2326-5205 ; 2326-5191
    ISSN (online) 2326-5205
    ISSN 2326-5191
    DOI 10.1002/art.42472
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 24: Show issues Location:
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  2. Book ; Online ; E-Book: Systemic Sclerosis

    Takehara, Kazuhiko / Fujimoto, Manabu / Kuwana, Masataka

    basic and translational research

    2016  

    Author's details Kazuhiko Takehara, Manabu Fujimoto, Masataka Kuwana, editors
    Keywords Sklerodermie ; Pathogenese
    Subject SSc ; Systemische Sclerose ; Systemische Sklerose ; Skleroderm ; Sklerodermia ; Scleroderma
    Language English
    Size 1 Online Ressource (VIII, 247 Seiten), Illustrationen
    Publisher Springer
    Publishing place Tokyo
    Publishing country Japan
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019389518
    ISBN 978-4-431-55708-1 ; 9784431557074 ; 4-431-55708-3 ; 4431557075
    DOI 10.1007/978-4-431-55708-1
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article: [Dermatomyositis].

    Fujimoto, Manabu

    Brain and nerve = Shinkei kenkyu no shinpo

    2022  Volume 75, Issue 7, Page(s) 847–854

    Abstract: Dermatomyositis is a heterogeneous disorder that can be classified into more homogeneous subsets. Autoantibodies are a useful tool in identifying such subsets because they correlate strongly with clinical phenotypes. In dermatomyositis, five disease- ... ...

    Abstract Dermatomyositis is a heterogeneous disorder that can be classified into more homogeneous subsets. Autoantibodies are a useful tool in identifying such subsets because they correlate strongly with clinical phenotypes. In dermatomyositis, five disease-specific autoantibodies have been established to date, including antiMi-2, anti-melanoma differentiation-associated gene 5, anti-transcriptional intermediary factor 1, anti-nuclear matrix protein 2, anti-transcriptional intermediary factor 1, and anti-small-ubiquitin-like activating enzyme antibodies. In addition, several novel autoantibodies have recently been demonstrated in patients with dermatomyositis, including anti-four-and-a-half-LIM-domain 1, anti-cell division cycle and apoptosis regulator protein 1, anti-specificity protein 4, anti-cortactin, and IgM anti-angiotensin converting enzyme 2 antibodies.
    MeSH term(s) Humans ; Dermatomyositis/diagnosis ; Autoantibodies ; Ubiquitin-Activating Enzymes
    Chemical Substances Autoantibodies ; Ubiquitin-Activating Enzymes (EC 6.2.1.45)
    Language Japanese
    Publishing date 2022-10-21
    Publishing country Japan
    Document type English Abstract ; Journal Article
    ZDB-ID 390389-8
    ISSN 1344-8129 ; 1881-6096 ; 0006-8969
    ISSN (online) 1344-8129
    ISSN 1881-6096 ; 0006-8969
    DOI 10.11477/mf.1416202430
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 398: Show issues Location:
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  4. Article: [Skin Manifestations in Dermatomyositis and Antisynthetase Syndrome].

    Fujimoto, Manabu

    Brain and nerve = Shinkei kenkyu no shinpo

    2021  Volume 73, Issue 2, Page(s) 137–146

    Abstract: Dermatomyositis and antisynthetase syndrome are among idiopathic inflammatory myopathies (myositis) that have skin lesions. In these disorders, skin symptoms often appear as the initial manifestations, and thus, their evaluation is critical for diagnosis. ...

    Abstract Dermatomyositis and antisynthetase syndrome are among idiopathic inflammatory myopathies (myositis) that have skin lesions. In these disorders, skin symptoms often appear as the initial manifestations, and thus, their evaluation is critical for diagnosis. Two components, "site" and "properties," are important for understanding the skin manifestations in myositis. The rash in these disorders is induced by Koebner's phenomenon, and is most frequently observed on the hands and face. Recent studies have shown that myositis-specific autoantibodies are useful tools for the diagnosis and classification of these diseases, as they are closely correlated with the clinical and histopathological phenotypes of myositis. It has recently become clear that each antibody is associated with characteristic skin manifestations, especially related to the properties of the skin lesions.
    MeSH term(s) Autoantibodies ; Dermatomyositis/complications ; Dermatomyositis/diagnosis ; Humans ; Myositis/complications ; Myositis/diagnosis ; Phenotype
    Chemical Substances Autoantibodies
    Language Japanese
    Publishing date 2021-02-02
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 390389-8
    ISSN 1344-8129 ; 1881-6096 ; 0006-8969
    ISSN (online) 1344-8129
    ISSN 1881-6096 ; 0006-8969
    DOI 10.11477/mf.1416201726
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  5. Article: [Dermatomyositis].

    Fujimoto, Manabu

    Brain and nerve = Shinkei kenkyu no shinpo

    2019  Volume 71, Issue 4, Page(s) 323–328

    Abstract: When examining the skin manifestations of dermatomyositis, it is important to systematically observe the frequently affected sites. The head and the hands are particularly important. It is critical to look not just for symptoms included in the ... ...

    Abstract When examining the skin manifestations of dermatomyositis, it is important to systematically observe the frequently affected sites. The head and the hands are particularly important. It is critical to look not just for symptoms included in the classification criteria, such as heliotrope rash and Gottron's papules/signs, but also for other rashes. Recent studies have demonstrated that specific autoantibodies are useful tools to subgroup dermatomyositis, and the skin manifestations are also closely correlated with these autoantibodies.
    MeSH term(s) Autoantibodies/blood ; Dermatomyositis/classification ; Dermatomyositis/pathology ; Humans
    Chemical Substances Autoantibodies
    Language Japanese
    Publishing date 2019-05-24
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 390389-8
    ISSN 1344-8129 ; 1881-6096 ; 0006-8969
    ISSN (online) 1344-8129
    ISSN 1881-6096 ; 0006-8969
    DOI 10.11477/mf.1416201269
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)

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  6. Article: [Dermatomyositis and Autoantibodies].

    Fujimoto, Manabu

    Brain and nerve = Shinkei kenkyu no shinpo

    2018  Volume 70, Issue 4, Page(s) 427–438

    Abstract: Recent studies have identified novel dermatomyositis-specific autoantibodies and revealed that disease-specific autoantibodies become positive at a high rate in this disease. Moreover, these autoantibodies have been demonstrated to show a strong ... ...

    Abstract Recent studies have identified novel dermatomyositis-specific autoantibodies and revealed that disease-specific autoantibodies become positive at a high rate in this disease. Moreover, these autoantibodies have been demonstrated to show a strong correlation with distinct clinical manifestations and complications such as interstitial lung disease and malignancy. Thus, these autoantibodies are now recognized as useful tools to classify this varied disease into more homogeneous subsets. In this review, the clinical significance of five dermatomyositis-specific autoantibodies, anti-Mi-2, anti-MDA5, anti-TIF1, anti-NXP2, and anti-SAE, was described.
    MeSH term(s) Adenosine Triphosphatases/immunology ; Apoptosis Regulatory Proteins/immunology ; Autoantibodies/immunology ; DNA-Binding Proteins/immunology ; Dermatomyositis/diagnosis ; Dermatomyositis/immunology ; Humans ; Interferon-Induced Helicase, IFIH1/immunology ; Lung Diseases, Interstitial/complications ; Mi-2 Nucleosome Remodeling and Deacetylase Complex/immunology ; Neoplasms/complications ; Nuclear Proteins/immunology ; Ubiquitin-Activating Enzymes/immunology
    Chemical Substances Apoptosis Regulatory Proteins ; Autoantibodies ; CHD4 protein, human ; DNA-Binding Proteins ; Nuclear Proteins ; TIAF1 protein, human ; Mi-2 Nucleosome Remodeling and Deacetylase Complex (EC 3.5.1.98) ; Adenosine Triphosphatases (EC 3.6.1.-) ; IFIH1 protein, human (EC 3.6.1.-) ; MORC3 protein, human (EC 3.6.1.-) ; Interferon-Induced Helicase, IFIH1 (EC 3.6.4.13) ; SAE1 protein, human (EC 6.2.1.45) ; Ubiquitin-Activating Enzymes (EC 6.2.1.45)
    Language Japanese
    Publishing date 2018-04-06
    Publishing country Japan
    Document type Journal Article ; Review
    ZDB-ID 390389-8
    ISSN 1344-8129 ; 1881-6096 ; 0006-8969
    ISSN (online) 1344-8129
    ISSN 1881-6096 ; 0006-8969
    DOI 10.11477/mf.1416201015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Development of a Psychological Scale for Measuring Disruptive Clinician Behavior.

    Fujimoto, Manabu / Shimamura, Mika / Miyazaki, Hiroaki / Inaba, Kazuto

    Journal of patient safety

    2023  Volume 19, Issue 8, Page(s) 564–572

    Abstract: Objectives: Disruptive clinician behavior worsens communication, information transfer, and teamwork, all of which negatively affect patient safety. Improving safety in medical care requires an accurate assessment of the damage caused by disruptive ... ...

    Abstract Objectives: Disruptive clinician behavior worsens communication, information transfer, and teamwork, all of which negatively affect patient safety. Improving safety in medical care requires an accurate assessment of the damage caused by disruptive clinician behavior. Psychometric scales complement case reports, but existing scales have significant limitations. Therefore, this study developed a psychometric scale based on the psychological paradigm to assess disruptive clinician behavior.
    Methods: The scale was developed through a sequence of steps. First, we used an open-ended questionnaire targeting 712 nurses, content analysis, and content validity assessment by 5 experts to determine valid items for disruptive clinical behavior. Next, an Internet questionnaire survey targeting 1000 health care staff, exploratory factor analysis, and subfactor analysis was conducted to identify necessary and sufficient factors. Then, we calculated difficulty level and discriminative power. We also conducted a field questionnaire survey targeting 84 staff in a hospital. Finally, we calculated ω coefficients and then used confirmatory factor analysis to verify the fit of the hypothesized model.
    Results: Our open-ended survey involving 478 nurses identified 47 codes in 9 categories. The questionnaire survey involving hospital 1000 medical staff identified 6 factors, with 1 factor subdivided into 4 subfactors and 1 into 2 subfactors. The goodness of fit of the hypothesized 10-factor models with factor pairs and groups was confirmed.
    Conclusions: We developed a psychometric scale measuring subjective assessments of harm covering various disruptive clinician behaviors. The scale complements interviews and case reports by generating valid, reliable scores for various disruptive clinician behaviors in health care institutions.
    MeSH term(s) Humans ; Problem Behavior ; Surveys and Questionnaires ; Patient Care ; Medical Staff, Hospital/psychology ; Psychometrics ; Reproducibility of Results
    Language English
    Publishing date 2023-10-17
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2394324-5
    ISSN 1549-8425 ; 1549-8417
    ISSN (online) 1549-8425
    ISSN 1549-8417
    DOI 10.1097/PTS.0000000000001162
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: A case of thiamazole-induced erythema nodosum.

    Hatano, Yoko / Nakagawa, Yukinobu / Tanemura, Atsushi / Fujimoto, Manabu

    The Journal of dermatology

    2023  Volume 50, Issue 10, Page(s) e335–e336

    MeSH term(s) Humans ; Methimazole ; Erythema Nodosum/chemically induced ; Erythema Nodosum/diagnosis ; Erythema Nodosum/drug therapy ; Antithyroid Agents ; Graves Disease
    Chemical Substances Methimazole (554Z48XN5E) ; Antithyroid Agents
    Language English
    Publishing date 2023-05-24
    Publishing country England
    Document type Case Reports ; Letter
    ZDB-ID 800103-0
    ISSN 1346-8138 ; 0385-2407
    ISSN (online) 1346-8138
    ISSN 0385-2407
    DOI 10.1111/1346-8138.16837
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  9. Article ; Online: ISID 2023: Celebrating the success and impact of international collaboration in dermatological research from JSID's perspective.

    Kabashima, Kenji / Fujimoto, Manabu / Ohyama, Manabu / Amagai, Masayuki

    Journal of dermatological science

    2023  Volume 111, Issue 3, Page(s) 78–82

    Language English
    Publishing date 2023-08-19
    Publishing country Netherlands
    Document type Clinical Conference
    ZDB-ID 1024446-3
    ISSN 1873-569X ; 0923-1811
    ISSN (online) 1873-569X
    ISSN 0923-1811
    DOI 10.1016/j.jdermsci.2023.08.004
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  10. Article ; Online: Glittering trail: Feces of scabies indicated by high-power-field dermatoscopy using UV-A light.

    Fujimoto, Megumi / Sakai, Hiroshi / Watanabe, Rei / Fujimoto, Manabu

    Journal of the American Academy of Dermatology

    2023  Volume 90, Issue 1, Page(s) e17–e18

    MeSH term(s) Humans ; Scabies/diagnosis ; Dermoscopy ; Feces
    Language English
    Publishing date 2023-06-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603641-7
    ISSN 1097-6787 ; 0190-9622
    ISSN (online) 1097-6787
    ISSN 0190-9622
    DOI 10.1016/j.jaad.2023.05.072
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