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Article ; Online: Changes in the corrected carotid flow time can predict spinal anesthesia-induced hypotension in patients undergoing cesarean delivery: an observational study.

Juri, Takashi / Suehiro, Koichi / Yasuda, Shinta / Kimura, Aya / Fujimoto, Yohei / Mori, Takashi

2024 Volume 38, Issue 1, Page(s) 105–113

Abstract: Purpose: Spinal anesthesia is a standard technique for cesarean delivery; however, it possesses a risk of hypotension. We hypothesised that the changes in the corrected flow time induced by the Trendelenburg position could predict the incidence of ... ...

Abstract	Purpose: Spinal anesthesia is a standard technique for cesarean delivery; however, it possesses a risk of hypotension. We hypothesised that the changes in the corrected flow time induced by the Trendelenburg position could predict the incidence of hypotension after spinal anesthesia for cesarean delivery. Methods: Patients undergoing elective cesarean delivery under spinal anesthesia were enrolled. Before anesthesia induction, corrected flow time was measured in the supine and Trendelenburg positions (FTc-1 and FTc-2, respectively). Additionally, a percent change in corrected flow time induced by the Trendelenburg position was defined as ΔFTc. The primary endpoint was to investigate the ability of ΔFTc to predict the incidence of spinal anesthesia-induced hypotension until delivery. The receiver operating characteristics curves to assess the ability of FTc-1, FTc-2, and ΔFTc to predict the incidence of hypotension were generated. Results: Finally, 40 patients were included, and of those, 26 (65%) developed spinal anesthesia-induced hypotension. The areas under the curve for FTc-1, FTc-2, and ΔFTc were 0.591 (95% CI: 0.424 to 0.743) (P = 0.380), 0.742 (95% CI: 0.579 to 0.867) (P = 0.004), and 0.882 (95% CI: 0.740 to 0.962) (P < 0.001) respectively, indicating ΔFTc as the best predictor among these three parameters. The best threshold for ΔFTc was 6.4% (sensitivity: 80.8% (95% CI: 53.8 to 96.2), specificity: 85.7% (95% CI: 42.9 to 100.0)). Conclusions: This study demonstrated that changes in the corrected carotid flow time induced by the Trendelenburg position could serve as a good predictor of spinal anesthesia-induced hypotension for cesarean delivery.
MeSH term(s)	Female ; Pregnancy ; Humans ; Anesthesia, Spinal/methods ; Hypotension, Controlled ; Anesthesia, Obstetrical/adverse effects ; Hypotension/etiology ; Patient Positioning/adverse effects
Language	English
Publishing date	2024-01-03
Publishing country	Japan
Document type	Observational Study ; Journal Article
ZDB-ID	1107821-2
ISSN	1438-8359 ; 0913-8668
ISSN (online)	1438-8359
ISSN	0913-8668
DOI	10.1007/s00540-023-03293-2
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Article ; Online: Corrigendum to Participation of the descending noradrenergic inhibitory system in the anti-hyperalgesic effect of acetaminophen in a rat model of inflammation. Life Sci. 286 (2021) 120030.

Juri, Takashi / Fujimoto, Yohei / Suehiro, Koichi / Nishikawa, Kiyonobu / Mori, Takashi

Life sciences

2022 Volume 295, Page(s) 120429

Language	English
Publishing date	2022-02-28
Publishing country	Netherlands
Document type	Published Erratum
ZDB-ID	3378-9
ISSN	1879-0631 ; 0024-3205
ISSN (online)	1879-0631
ISSN	0024-3205
DOI	10.1016/j.lfs.2022.120429
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Article ; Online: Participation of the descending noradrenergic inhibitory system in the anti-hyperalgesic effect of acetaminophen in a rat model of inflammation.

Juri, Takashi / Fujimoto, Yohei / Suehiro, Koichi / Nishikawa, Kiyonobu / Mori, Takashi

Life sciences

2021 Volume 286, Page(s) 120030

Abstract: Aims: This study investigated the relationship between the analgesic efficacy of acetaminophen and the descending noradrenergic systems using rodent models of inflammatory pain.: Main methods: Inflammatory pain models were established by carrageenan ... ...

Abstract	Aims: This study investigated the relationship between the analgesic efficacy of acetaminophen and the descending noradrenergic systems using rodent models of inflammatory pain. Main methods: Inflammatory pain models were established by carrageenan injection into rats' paws. The models were defined as acute (4 h after carrageenan injection), subacute (24 h after carrageenan injection), and late (1 week after carrageenan injection) phase. To evaluate intravenous acetaminophen treatment, the withdrawal threshold to mechanical stimuli was assessed simultaneously with in vivo microdialysis assay of noradrenaline levels in the locus coeruleus (LC). Further analyses were performed to observe the effect of yohimbine on the treatment and the impact of AM404 treatment, a metabolite of acetaminophen, on noradrenaline levels in the LC. Key findings: In all phases, intravenous acetaminophen had a significant anti-hyperalgesic effect (p < 0.05). There was a significant time-dependent increase in the noradrenaline concentration within the LC (acetaminophen versus saline treatment; at 30 min, p < 0.001; 60 min, p < 0.01) in the subacute pain model, but not in the acute and late phase pain models. Intrathecal pre-injection of yohimbine attenuated the anti-hyperalgesic effect after acetaminophen injection only in the subacute model (p < 0.05). In the subacute pain model, intracerebroventricular administration of AM404 showed the same trend in noradrenaline levels as acetaminophen administration (AM404 versus vehicle group at 30 min, p < 0.001). Significance: We found the descending noradrenergic inhibitory system is involved in the antinociceptive action of acetaminophen in the subacute phase of inflammatory pain.
MeSH term(s)	Acetaminophen/pharmacology ; Acetaminophen/therapeutic use ; Animals ; Carrageenan/administration & dosage ; Disease Models, Animal ; Hyperalgesia/drug therapy ; Inflammation/chemically induced ; Inflammation/drug therapy ; Locus Coeruleus/drug effects ; Locus Coeruleus/metabolism ; Male ; Norepinephrine/antagonists & inhibitors ; Rats ; Rats, Sprague-Dawley ; Spinal Cord/drug effects ; Spinal Cord/metabolism ; Yohimbine/pharmacology
Chemical Substances	Yohimbine (2Y49VWD90Q) ; Acetaminophen (362O9ITL9D) ; Carrageenan (9000-07-1) ; Norepinephrine (X4W3ENH1CV)
Language	English
Publishing date	2021-10-08
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	3378-9
ISSN	1879-0631 ; 0024-3205
ISSN (online)	1879-0631
ISSN	0024-3205
DOI	10.1016/j.lfs.2021.120030
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Article ; Online: Participation of the descending noradrenergic inhibitory system in the anti-hyperalgesic effect of acetaminophen in a rat model of inflammation [Corrigendum: Apr. 2022, v. 295, p. 120429]

Juri, Takashi / Fujimoto, Yohei / Suehiro, Koichi / Nishikawa, Kiyonobu / Mori, Takashi

Life sciences. 2021 Dec. 01, v. 286, p. 120030

2021 , Page(s) 120030

Abstract: This study investigated the relationship between the analgesic efficacy of acetaminophen and the descending noradrenergic systems using rodent models of inflammatory pain.Inflammatory pain models were established by carrageenan injection into rats' paws. ...

Abstract	This study investigated the relationship between the analgesic efficacy of acetaminophen and the descending noradrenergic systems using rodent models of inflammatory pain.Inflammatory pain models were established by carrageenan injection into rats' paws. The models were defined as acute (4 h after carrageenan injection), subacute (24 h after carrageenan injection), and late (1 week after carrageenan injection) phase. To evaluate intravenous acetaminophen treatment, the withdrawal threshold to mechanical stimuli was assessed simultaneously with in vivo microdialysis assay of noradrenaline levels in the locus coeruleus (LC). Further analyses were performed to observe the effect of yohimbine on the treatment and the impact of AM404 treatment, a metabolite of acetaminophen, on noradrenaline levels in the LC.In all phases, intravenous acetaminophen had a significant anti-hyperalgesic effect (p < 0.05). There was a significant time-dependent increase in the noradrenaline concentration within the LC (acetaminophen versus saline treatment; at 30 min, p < 0.001; 60 min, p < 0.01) in the subacute pain model, but not in the acute and late phase pain models. Intrathecal pre-injection of yohimbine attenuated the anti-hyperalgesic effect after acetaminophen injection only in the subacute model (p < 0.05). In the subacute pain model, intracerebroventricular administration of AM404 showed the same trend in noradrenaline levels as acetaminophen administration (AM404 versus vehicle group at 30 min, p < 0.001).We found the descending noradrenergic inhibitory system is involved in the antinociceptive action of acetaminophen in the subacute phase of inflammatory pain.
Keywords	acetaminophen ; animal models ; brain stem ; carrageenan ; inflammation ; intravenous injection ; metabolites ; microdialysis ; norepinephrine ; pain ; yohimbine ; AM404 ; Descending noradrenergic inhibitory system ; Inflammatory pain ; Subacute pain
Language	English
Dates of publication	2021-1201
Size	p. 120030
Publishing place	Elsevier Inc.
Document type	Article ; Online
ZDB-ID	3378-9
ISSN	1879-0631 ; 0024-3205
ISSN (online)	1879-0631
ISSN	0024-3205
DOI	10.1016/j.lfs.2021.120030
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Article ; Online: Validation of Continuous Noninvasive Blood Pressure Monitoring Using Error Grid Analysis.

Juri, Takashi / Suehiro, Koichi / Kanematsu, Rieko / Takahashi, Kanae / Fujimoto, Yohei / Tanaka, Katsuaki / Mori, Takashi

Anesthesia and analgesia

2021 Volume 134, Issue 4, Page(s) 773–780

Abstract: Background: Error grid analysis was recently proposed to compare blood pressure obtained by 2 measurement methods. This study aimed to compare continuous noninvasive blood pressure (CNBP) with invasive blood pressure (IBP) using the error grid analysis ... ...

Abstract	Background: Error grid analysis was recently proposed to compare blood pressure obtained by 2 measurement methods. This study aimed to compare continuous noninvasive blood pressure (CNBP) with invasive blood pressure (IBP) using the error grid analysis and investigate the confounding risk factors attributable to the differences between CNBP and IBP. Methods: Sixty adult patients undergoing general anesthesia were prospectively enrolled. Simultaneous comparative data regarding CNBP and IBP were collected. The Bland-Altman analysis was conducted to compare CNBP and IBP for systolic blood pressure (SBP) and mean blood pressure (MBP; acceptable accuracy: mean bias <5 mm Hg; standard deviation <8 mm Hg). The clinical relevance of the discrepancies between CNBP and IBP was evaluated by the error grid analysis, which classifies the differences into 5 zones from "no risk" (A) to "dangerous risk" (E). Additionally, an ordinal logistic regression analysis was performed to evaluate the relationship between the risk zones for MBP, classified by the error grid analysis and covariates of interest. Results: A total of 10,663 pairs of CNBP/IBP were finally analyzed. The Bland-Altman analysis showed an acceptable accuracy with a bias of -3.3 ± 5.6 mm Hg for MBP but a poor accuracy with a bias of 5.4 ± 10.5 mm Hg for SBP. The error grid analysis showed the proportions of zones A to E as 96.7%, 3.2%, 0.1%, 0%, and 0% for SBP, respectively, and 72.0%, 27.9%, 0.1%, 0%, and 0% for MBP, respectively. The finger cuff missed 23.9% of epochs when SBP <90 mm Hg and 55.3% of epochs when MBP <65 mm Hg. The ordinal logistic regression analysis revealed that older age (adjusted odds ratio for decade: 1.54, 95% confidence interval [CI], 1.15-2.08; P = .004) and length of time from the initiation of finger cuff inflation (adjusted odds ratio for 60 minutes: 1.40, 95% CI, 1.13-1.73; P = .002) were significant factors of being in a more dangerous zone of the error grid. Conclusions: The error grid analysis revealed the larger clinical discrepancy between CNBP and IBP in MBP compared with that in SBP. Old age and longer finger cuff inflation time were significant factors of being in a more dangerous zone of the error grid, which could affect the hemodynamic management during surgery.
MeSH term(s)	Adult ; Arterial Pressure/physiology ; Blood Pressure ; Blood Pressure Determination/methods ; Blood Pressure Monitors ; Fingers ; Humans
Language	English
Publishing date	2021-12-30
Publishing country	United States
Document type	Journal Article
ZDB-ID	80032-6
ISSN	1526-7598 ; 0003-2999
ISSN (online)	1526-7598
ISSN	0003-2999
DOI	10.1213/ANE.0000000000005882
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Article ; Online: Protective effects of hydrogen gas against spinal cord ischemia-reperfusion injury.

Kimura, Aya / Suehiro, Koichi / Mukai, Akira / Fujimoto, Yohei / Funao, Tomoharu / Yamada, Tokuhiro / Mori, Takashi

The Journal of thoracic and cardiovascular surgery

2021 Volume 164, Issue 6, Page(s) e269–e283

Abstract: Objective: This experimental study aimed to assess the efficacy of hydrogen gas inhalation against spinal cord ischemia-reperfusion injury and reveal its mechanism by measuring glutamate concentration in the ventral horn using an in vivo microdialysis ... ...

Abstract	Objective: This experimental study aimed to assess the efficacy of hydrogen gas inhalation against spinal cord ischemia-reperfusion injury and reveal its mechanism by measuring glutamate concentration in the ventral horn using an in vivo microdialysis method. Methods: Male Sprague-Dawley rats were divided into the following 6 groups: sham, only spinal ischemia, 3% hydrogen gas (spinal ischemia + 3% hydrogen gas), 2% hydrogen gas (spinal ischemia + 2% hydrogen gas), 1% hydrogen gas (spinal ischemia + 1% hydrogen gas), and hydrogen gas dihydrokainate (spinal ischemia + dihydrokainate [selective inhibitor of glutamate transporter-1] + 3% hydrogen gas). Hydrogen gas inhalation was initiated 10 minutes before the ischemia. For the hydrogen gas dihydrokainate group, glutamate transporter-1 inhibitor was administered 20 minutes before the ischemia. Immunofluorescence was performed to assess the expression of glutamate transporter-1 in the ventral horn. Results: The increase in extracellular glutamate induced by spinal ischemia was significantly suppressed by 3% hydrogen gas inhalation (P < .05). This effect was produced in increasing order: 1%, 2%, and 3%. Conversely, the preadministration of glutamate transporter-1 inhibitor diminished the suppression of spinal ischemia-induced glutamate increase observed during the inhalation of 3% hydrogen gas. Immunofluorescence indicated the expression of glutamate transporter-1 in the spinal ischemia group was significantly decreased compared with the sham group, which was attenuated by 3% hydrogen gas inhalation (P < .05). Conclusions: Our study demonstrated hydrogen gas inhalation exhibits a protective and concentration-dependent effect against spinal ischemic injury, and glutamate transporter-1 has an important role in the protective effects against spinal cord injury.
MeSH term(s)	Animals ; Male ; Rats ; Amino Acid Transport System X-AG/metabolism ; Disease Models, Animal ; Glutamates/metabolism ; Hydrogen/pharmacology ; Ischemia ; Rats, Sprague-Dawley ; Reperfusion Injury/prevention & control ; Reperfusion Injury/metabolism ; Spinal Cord/metabolism ; Spinal Cord Ischemia/prevention & control ; Spinal Cord Ischemia/metabolism
Chemical Substances	Amino Acid Transport System X-AG ; Glutamates ; Hydrogen (7YNJ3PO35Z)
Language	English
Publishing date	2021-05-04
Publishing country	United States
Document type	Journal Article
ZDB-ID	3104-5
ISSN	1097-685X ; 0022-5223
ISSN (online)	1097-685X
ISSN	0022-5223
DOI	10.1016/j.jtcvs.2021.04.077
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Article ; Online: Error grid analysis for risk management in the difference between invasive and noninvasive blood pressure measurements.

Juri, Takashi / Suehiro, Koichi / Uchimoto, Akihiro / Go, Hirofumi / Fujimoto, Yohei / Mori, Takashi / Nishikawa, Kiyonobu

Journal of anesthesia

2021 Volume 35, Issue 2, Page(s) 189–196

Abstract: Purpose: Invasive arterial blood pressure (IAP) and noninvasive blood pressure (NIBP) measurements are both common methods. Recently, a new method of error grid analysis was proposed to compare blood pressure obtained using two measurement methods. This ...

Abstract	Purpose: Invasive arterial blood pressure (IAP) and noninvasive blood pressure (NIBP) measurements are both common methods. Recently, a new method of error grid analysis was proposed to compare blood pressure obtained using two measurement methods. This study aimed to compare IAP and NIBP measurements using the error grid analysis and investigate potential confounding factors affecting the discrepancies between IAP and NIBP. Methods: Adult patients who underwent general anesthesia in the supine position with both IAP and NIBP measurements were retrospectively investigated. The error grid analyses were performed to compare IAP and NIBP. In the error grid analysis, the clinical relevance of the discrepancies between IAP and NIBP was evaluated and classified into five zones from no risk (A) to dangerous risk (E). Results: Overall, data of 1934 IAP/NIBP measurement pairs from 100 patients were collected. The error grid analysis revealed that the proportions of zones A-E for systolic blood pressure were 96.4%, 3.5%, 0.05%, 0%, and 0%, respectively. In contrast, the proportions for mean blood pressure were 82.5%, 16.7%, 0.8%, 0%, and 0%, respectively. The multiple regression analysis revealed that continuous phenylephrine administration (p = 0.016) and age (p = 0.044) were the significant factors of an increased clinical risk of the differences in mean blood pressure. Conclusions: The error grid analysis indicated that the differences between IAP and NIBP for mean blood pressure were not clinically acceptable and had the risk of leading to unnecessary treatments. Continuous phenylephrine administration and age were the significant factors of an increased clinical risk of the discrepancies between IAP and NIBP.
MeSH term(s)	Adult ; Arterial Pressure ; Blood Pressure ; Blood Pressure Determination ; Humans ; Retrospective Studies ; Risk Management
Language	English
Publishing date	2021-01-11
Publishing country	Japan
Document type	Journal Article
ZDB-ID	1107821-2
ISSN	1438-8359 ; 0913-8668
ISSN (online)	1438-8359
ISSN	0913-8668
DOI	10.1007/s00540-020-02893-6
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Article ; Online: Protective effects of remote ischemic preconditioning against spinal cord ischemia-reperfusion injury in rats.

Mukai, Akira / Suehiro, Koichi / Kimura, Aya / Fujimoto, Yohei / Funao, Tomoharu / Mori, Takashi / Nishikawa, Kiyonobu

The Journal of thoracic and cardiovascular surgery

2020 Volume 163, Issue 2, Page(s) e137–e156

Abstract: Objectives: We aimed to investigate the protective effect of remote ischemic preconditioning against spinal cord ischemia and find a clue to its mechanism by measuring glutamate concentrations in the spinal ventral horn.: Methods: Male Sprague-Dawley ...

Abstract	Objectives: We aimed to investigate the protective effect of remote ischemic preconditioning against spinal cord ischemia and find a clue to its mechanism by measuring glutamate concentrations in the spinal ventral horn. Methods: Male Sprague-Dawley rats were divided into 5 groups (n = 6 in each group) as follows: sham; SCI (only spinal cord ischemia); RIPC/SCI (perform remote ischemic preconditioning before spinal cord ischemia); MK-801/RIPC/SCI (administer MK-801, N-methyl-D-aspartate receptor antagonist, before remote ischemic preconditioning); and MK-801/SCI (administer MK-801 without remote ischemic preconditioning). Remote ischemic preconditioning was achieved by brief limb ischemia 80 minutes before spinal cord ischemia. MK-801 (1 mg/kg, intravenous) was administered 60 minutes before remote ischemic preconditioning. The glutamate concentration in the ventral horn was measured by microdialysis for 130 minutes after spinal cord ischemia. Immunofluorescence was also performed to evaluate the expression of N-methyl-D-aspartate receptor 2B subunit in the ventral horn 130 minutes after spinal cord ischemia. Results: The glutamate concentrations in the spinal cord ischemia group were significantly higher than in the sham group at all time points (P < .01). Remote ischemic preconditioning attenuated the spinal cord ischemia-induced glutamate increase. When MK-801 was preadministered before remote ischemic preconditioning, glutamate concentration was increased after spinal cord ischemia (P < .01). Immunofluorescence showed that remote ischemic preconditioning prevented the increase in the expression of N-methyl-D-aspartate receptor 2B subunit on the surface of motor neurons (P = .047). Conclusions: Our results showed that remote ischemic preconditioning prevented spinal cord ischemia-induced extracellular glutamate increase in ventral horn and suppressed N-methyl-D-aspartate receptor 2B subunit expression.
MeSH term(s)	Animals ; Anterior Horn Cells/metabolism ; Dizocilpine Maleate/pharmacology ; Glutamic Acid/analysis ; Ischemic Preconditioning/methods ; Neuroprotective Agents/pharmacology ; Rats ; Rats, Sprague-Dawley ; Receptors, N-Methyl-D-Aspartate/antagonists & inhibitors ; Reperfusion Injury/metabolism ; Reperfusion Injury/prevention & control ; Spinal Cord/blood supply ; Spinal Cord Ischemia/metabolism ; Spinal Cord Ischemia/prevention & control ; Treatment Outcome
Chemical Substances	Neuroprotective Agents ; Receptors, N-Methyl-D-Aspartate ; Glutamic Acid (3KX376GY7L) ; Dizocilpine Maleate (6LR8C1B66Q)
Language	English
Publishing date	2020-04-11
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	3104-5
ISSN	1097-685X ; 0022-5223
ISSN (online)	1097-685X
ISSN	0022-5223
DOI	10.1016/j.jtcvs.2020.03.094
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Article ; Online: Hemodynamic Changes via the Lung Recruitment Maneuver Can Predict Fluid Responsiveness in Stroke Volume and Arterial Pressure During One-Lung Ventilation.

Kimura, Aya / Suehiro, Koichi / Juri, Takashi / Fujimoto, Yohei / Yoshida, Hisako / Tanaka, Katsuaki / Mori, Takashi / Nishikawa, Kiyonobu

Anesthesia and analgesia

2021 Volume 133, Issue 1, Page(s) 44–52

Abstract: Background: We aimed to evaluate the ability of lung recruitment maneuver-induced hemodynamic changes to predict fluid responsiveness in patients undergoing lung-protective ventilation during one-lung ventilation (OLV).: Methods: Thirty patients ... ...

Abstract	Background: We aimed to evaluate the ability of lung recruitment maneuver-induced hemodynamic changes to predict fluid responsiveness in patients undergoing lung-protective ventilation during one-lung ventilation (OLV). Methods: Thirty patients undergoing thoracic surgery with OLV (tidal volume: 6 mL/kg of ideal body weight and positive end-expiratory pressure: 5 cm H2O) were enrolled. The study protocol began 30 minutes after starting OLV. Simultaneous recordings were performed for hemodynamic variables of heart rate, mean arterial pressure (MAP), stroke volume (SV), pulse pressure variation (PPV), and stroke volume variation (SVV) were recorded at 4 time points: before recruitment maneuver (continuous airway pressure: 30 cm H2O for 30 seconds), at the end of recruitment maneuver, and before and after volume loading (250 mL over 10 minutes). Patients were recognized as fluid responders if the increase in SV or MAP was >10%. Receiver operating characteristic curves for percent decrease in SV and MAP by recruitment maneuver (ΔSVRM and ΔMAPRM, respectively) were generated to evaluate the ability to discriminate fluid responders from nonresponders. The gray-zone approach was applied for ΔSVRM and ΔMAPRM. Results: Of 30 patients, there were 17 SV-responders (57%) and 12 blood pressure (BP)-responders (40%). Area under the curve (AUC) for ΔSVRM to discriminate SV-responders from nonresponders was 0.84 (95% confidence interval [CI], 0.67-0.95; P < .001). The best threshold for ΔSVRM to discriminate the SV-responders was -23.7% (95% CI, -41.2 to -17.8; sensitivity, 76.5% [95% CI, 50.1-93.2]; specificity, 84.6% [95% CI, 54.6-98.1]). For BP-responders, AUC for ΔMAPRM was 0.80 (95% CI, 0.61-0.92, P < .001). The best threshold for ΔMAPRM was -17.3% (95% CI, -23.9 to -5.1; sensitivity, 75.0% [95% CI, 42.8-94.5]; specificity, 77.8% [95% CI, 52.4-93.6]). With the gray-zone approach, the inconclusive range of ΔSVRM for SV-responders was -40.1% to -13.8% including 13 (43%) patients, and that of ΔMAPRM was -23.9% to -5.1%, which included 16 (53%) patients. Conclusions: ΔSVRM and ΔMAPRM could predict hemodynamic responses after volume expansion during OLV.
MeSH term(s)	Aged ; Arterial Pressure/physiology ; Female ; Fluid Therapy/methods ; Forecasting ; Hemodynamics/physiology ; Humans ; Male ; Middle Aged ; One-Lung Ventilation/methods ; Registries ; Stroke Volume/physiology ; Thoracic Surgical Procedures/methods ; Tidal Volume/physiology
Language	English
Publishing date	2021-03-09
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	80032-6
ISSN	1526-7598 ; 0003-2999
ISSN (online)	1526-7598
ISSN	0003-2999
DOI	10.1213/ANE.0000000000005375
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Article ; Online: Transcutaneous near-infrared spectroscopy for monitoring spinal cord ischemia: an experimental study in swine.

Suehiro, Koichi / Funao, Tomoharu / Fujimoto, Yohei / Mukai, Akira / Nakamura, Mitsuyo / Nishikawa, Kiyonobu

Journal of clinical monitoring and computing

2016 Volume 31, Issue 5, Page(s) 975–979

Abstract: We aimed to assess the ability of near-infrared spectroscopy (NIRS) to detect spinal cord ischemia, and to evaluate changes in regional oxygen saturation ( ... ...

Abstract	We aimed to assess the ability of near-infrared spectroscopy (NIRS) to detect spinal cord ischemia, and to evaluate changes in regional oxygen saturation (rSO
MeSH term(s)	Animals ; Aorta/diagnostic imaging ; Aorta, Thoracic ; Constriction ; Disease Models, Animal ; Drainage ; Female ; Hemodynamics ; Ischemia/diagnosis ; Oxygen/chemistry ; Spectroscopy, Near-Infrared/methods ; Spinal Cord/blood supply ; Spinal Cord/pathology ; Spinal Cord Ischemia/diagnostic imaging ; Spinal Cord Ischemia/pathology ; Swine
Chemical Substances	Oxygen (S88TT14065)
Language	English
Publishing date	2016-08-27
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1418733-4
ISSN	1573-2614 ; 1387-1307 ; 0748-1977
ISSN (online)	1573-2614
ISSN	1387-1307 ; 0748-1977
DOI	10.1007/s10877-016-9931-8
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