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  1. Article ; Online: Tao-Hong-Si-Wu decoction reduces ischemia reperfusion rat myoblast cells calcium overloading and inflammation through the Wnt/IP3R/CAMKII pathway.

    Fuping, Zhu / Wuping, Li / Linhua, Wang / Chengxi, Pan / Fuqiang, Zhou / Yi, Zhang / Aijun, Wang

    Journal of cellular biochemistry

    2019  Volume 120, Issue 8, Page(s) 13095–13106

    Abstract: Limb ischemia reperfusion (LIRI) injury is associated with serious local and systemic effects. Reperfusion may augment tissue injury in excess of that produced by ischemia alone. Calcium overloading and inflammation are considered to be two of the ... ...

    Abstract Limb ischemia reperfusion (LIRI) injury is associated with serious local and systemic effects. Reperfusion may augment tissue injury in excess of that produced by ischemia alone. Calcium overloading and inflammation are considered to be two of the pathological mechanisms of limb ischemia/reperfusion (I/R) injury. Tao-Hong-Si-Wu decoction (THSWD) is a traditional Chinese herbal medicine with a powerful anti-inflammatory properties. We studied the probable restorative effect of THSWD on limb I/R-induced calcium overloading and inflammation in myoblast obtained from gastrocnemius muscle tissues of Sprague-Dawley rats (Frizzled Z5,a wnt5a blocker; KN-93, a calmodulin-dependent protein kinase II (CamkII) blocker; XeC, a IP3R blocker as positive controls). The simulated ischemia and reperfusion(I/R) solutions were used to imitate LIRI environment. The results showed that after I/R treatment, the secretion of proinflammatory factors (TNF-α and IL-1β) and Wnt5a/Ca
    MeSH term(s) Animals ; Calcium/metabolism ; Calcium-Calmodulin-Dependent Protein Kinase Type 2/genetics ; Calcium-Calmodulin-Dependent Protein Kinase Type 2/metabolism ; Drugs, Chinese Herbal/pharmacology ; Gene Expression/drug effects ; Inflammation/genetics ; Inflammation/metabolism ; Inflammation/prevention & control ; Inositol 1,4,5-Trisphosphate Receptors/genetics ; Inositol 1,4,5-Trisphosphate Receptors/metabolism ; Male ; Myoblasts/cytology ; Myoblasts/drug effects ; Myoblasts/metabolism ; Phytotherapy/methods ; Proteins/genetics ; Proteins/metabolism ; Rats, Sprague-Dawley ; Reperfusion Injury/genetics ; Reperfusion Injury/metabolism ; Reperfusion Injury/prevention & control ; Signal Transduction/drug effects ; Signal Transduction/genetics ; Wnt-5a Protein/genetics ; Wnt-5a Protein/metabolism
    Chemical Substances Drugs, Chinese Herbal ; Inositol 1,4,5-Trisphosphate Receptors ; Proteins ; Taohong Siwu decoction II ; Wnt-5a Protein ; Calcium-Calmodulin-Dependent Protein Kinase Type 2 (EC 2.7.11.17) ; Calcium (SY7Q814VUP)
    Language English
    Publishing date 2019-04-05
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 392402-6
    ISSN 1097-4644 ; 0730-2312
    ISSN (online) 1097-4644
    ISSN 0730-2312
    DOI 10.1002/jcb.28582
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Graph-regularized low-rank representation for aerosol optical depth retrieval

    Sun, Yubao / Fuping Zhu / Hucheng Pei / Qingshan Liu / Renlong Hang

    International journal of remote sensing. 2016 Dec. 16, v. 37, no. 24

    2016  

    Abstract: In this article, we propose a novel data-driven regression model for aerosol optical depth (AOD) retrieval. First, we adopt a low-rank representation (LRR) model to learn a powerful representation of the spectral response. Then, a graph regularization is ...

    Abstract In this article, we propose a novel data-driven regression model for aerosol optical depth (AOD) retrieval. First, we adopt a low-rank representation (LRR) model to learn a powerful representation of the spectral response. Then, a graph regularization is incorporated into the LRR model to capture the local structure information and the non-linear property of the remote-sensing data. Since it is easy to acquire the rich results retrieved by satellite, we use them as a baseline to construct the graph. Finally, the learned feature representation is fed into Support Vector Machines (SVMs) to retrieve AOD. Experiments are conducted on two widely used data sets acquired by different sensors, and the experimental results show that the proposed method can achieve superior performance compared to the physical models and other state-of-the-art empirical models.
    Keywords aerosols ; data collection ; physical models ; regression analysis ; remote sensing ; satellites ; support vector machines
    Language English
    Dates of publication 2016-1216
    Size p. 5749-5762.
    Publishing place Taylor & Francis
    Document type Article
    ZDB-ID 1497529-4
    ISSN 1366-5901 ; 0143-1161
    ISSN (online) 1366-5901
    ISSN 0143-1161
    DOI 10.1080/01431161.2016.1249302
    Database NAL-Catalogue (AGRICOLA)

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