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  1. Article ; Online: Cost Modifications during the Early Years of the Use of the National Cardiovascular Data Registry for Quality Improvement.

    Barros, Pedro Gabriel Melo de / Li, John / Tremblay, Christine / Okada, Mariana Yumi / Sznejder, Henry / Furlan, Valter / Vasconcellos, Rafael

    Clinics (Sao Paulo, Brazil)

    2020  Volume 75, Page(s) e1708

    Abstract: Objectives: Quality improvement (QI) initiatives based on data from international registries have been reported previously; however, there is a lack of information on the impact on the costs of medical care associated with the use of these tools.: ... ...

    Abstract Objectives: Quality improvement (QI) initiatives based on data from international registries have been reported previously; however, there is a lack of information on the impact on the costs of medical care associated with the use of these tools.
    Methods: Patients admitted due to myocardial infarction (MI), included in the ACTION Registry® and CathPCI Registry®, in a private Brazilian hospital (i.e., the reference hospital) were analyzed. The costs of care of these patients were compared to the costs of MI admissions in nine similar hospitals not included in the same QI program. Regression models were used to analyze the cost change over time between the two groups of hospitals. Readmission rates were compared using logistic regression, adjusting for the same variables as in the cost model.
    Results: Overall, the annual medical cost inflation in Brazil was higher than the annual cost trend in the reference hospital during the period of analysis. Moreover, the annual in-hospital costs indicate that the reference hospital has a statistically significant 6% lower cost trend for patients with acute MI, compared to patients with the same diagnostic code in the comparison hospitals group, in an adjusted analysis (p-value=0.041). Using multivariable analysis, the readmission rates were also found to be significantly lower in the reference hospital than in the comparison hospitals, with an odds ratio of 0.68 (p-value=0.042).
    Conclusion: The use of the NCDR® as a benchmark to guide QI programs outside the United States was associated with the positive impact of bending the cost curve to below that of national medical inflation and the comparison hospitals' costs, with a lower incidence of hospital readmission.
    MeSH term(s) Brazil ; Hospitals ; Humans ; Patient Readmission ; Quality Improvement ; Registries ; United States
    Language English
    Publishing date 2020-08-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2182801-5
    ISSN 1980-5322 ; 1807-5932
    ISSN (online) 1980-5322
    ISSN 1807-5932
    DOI 10.6061/clinics/2020/e1708
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A Coronary Artery Anomaly Presenting as Acute Coronary Syndrome: A Case Report.

    de A Chaud, Mariana S / Agostinho, Camila A / Malafaia, Felipe L / Sampaio, Márcio C / Chaccur, Paulo / de Barros E Silva, Pedro Gabriel Melo / Ribeiro, Expedito E / Garcia, José Carlos Teixeira / Furlan, Valter / Ribeiro, Henrique B

    The American journal of case reports

    2021  Volume 22, Page(s) e931561

    Abstract: BACKGROUND Coronary artery anomalies (CAAs) are rare congenital malformations with different clinical presentations and pathophysiological mechanisms. These anomalies are frequently the cause of sudden death in young patients. Most CAAs are incidental ... ...

    Abstract BACKGROUND Coronary artery anomalies (CAAs) are rare congenital malformations with different clinical presentations and pathophysiological mechanisms. These anomalies are frequently the cause of sudden death in young patients. Most CAAs are incidental findings owing to the lack of symptoms; however, they may be associated with acute coronary syndrome in rare cases. CASE REPORT We describe the case of a 47-year-old man who presented with a 1-day history of progressive typical chest pain and elevated troponin levels. The patient underwent a coronary angiography, which unveiled the anomalous origin of the left main coronary artery arising from the right coronary artery, with an interarterial course between the ascending aorta and the pulmonary artery, without coronary artery disease. Coronary computed tomography angiography confirmed the CAA and its relationship with the symptoms. An uneventful coronary artery bypass graft was undertaken, and at the 1-year follow-up, the patient was asymptomatic, with a normal stress test. CONCLUSIONS This case depicts the presentation of atypical acute coronary syndrome in a young patient with a rare CAA. In such patients, coronary angiography and coronary computed tomography angiography are essential tools to confirm the diagnosis and to determine treatment. Although controversial, in young individuals presenting CAA with an interarterial course, such as the left main coronary artery arising from the right coronary artery, coronary artery bypass graft may be an important treatment option to avoid sudden death in the future.
    MeSH term(s) Acute Coronary Syndrome/diagnosis ; Acute Coronary Syndrome/etiology ; Coronary Angiography ; Coronary Artery Disease ; Coronary Vessel Anomalies/diagnosis ; Coronary Vessel Anomalies/diagnostic imaging ; Humans ; Male ; Middle Aged
    Language English
    Publishing date 2021-09-01
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2517183-5
    ISSN 1941-5923 ; 1941-5923
    ISSN (online) 1941-5923
    ISSN 1941-5923
    DOI 10.12659/AJCR.931561
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Chest Pain Network with Support of Telemedicine: Impact on Reperfusion Therapy and Clinical Outcomes After 8 Years of Experience.

    de Barros E Silva, Pedro Gabriel Melo / Macedo, Thiago Andrade / Lopes, Renato D / Okada, Mariana Y / Frigini, Tiago / Roveri, Patricia O / Balada, Rodrigo / de Macedo, Lucas Silva / Furlan, Valter

    Telemedicine reports

    2021  Volume 2, Issue 1, Page(s) 284–292

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2021-12-22
    Publishing country United States
    Document type Journal Article
    ISSN 2692-4366
    ISSN (online) 2692-4366
    DOI 10.1089/tmr.2021.0033
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Acute Myocarditis Associated with Acute Myocardial Infarction.

    Magalhães, Maycon Juglas Linhares / Gomes de Farias, Lucas de Pádua / Baptista, Luciana de Pádua Silva / Sampaio, Marcio Campos / Guimarães, Patrícia O / do Baruzzi, Antonio Claudio Amaral / de Barros E Silva, Pedro Gabriel Melo / Furlan, Valter

    Radiology. Cardiothoracic imaging

    2021  Volume 3, Issue 1, Page(s) e200469

    Abstract: Concomitant acute myocarditis and acute coronary thrombosis is a rare presentation of acute chest pain in the emergency department, although the association between acute infections with a variety of pathogens and an increased risk of myocardial ... ...

    Abstract Concomitant acute myocarditis and acute coronary thrombosis is a rare presentation of acute chest pain in the emergency department, although the association between acute infections with a variety of pathogens and an increased risk of myocardial infarction has been reported. A case of acute myocardial infarction associated with acute myocarditis caused by coronavirus 229E in a middle-aged man without risk factors for coronary artery disease is described here. Coronary CT angiography with late enhancement protocol revealed areas of myocarditis and infarction, and cardiac MRI and coronary angiography were then performed. © RSNA, 2021.
    Language English
    Publishing date 2021-01-28
    Publishing country United States
    Document type Case Reports
    ISSN 2638-6135
    ISSN (online) 2638-6135
    DOI 10.1148/ryct.2021200469
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Reduction in the Number of Patients with Suspected and Confirmed Acute Coronary Syndrome during the early months of the Covid-19 Pandemic: Analysis of a Brazilian Network.

    Silva, Pedro Gabriel Melo de Barros E / Dutra, Ana Amaral Ferreira / Manfredi, Adriana Bertolami / Sampaio, Pedro Paulo Nogueres / Correa, Celso Musa / Griz, Hemilo Borba / Setta, Daniel / Furlan, Valter

    Arquivos brasileiros de cardiologia

    2021  Volume 116, Issue 5, Page(s) 1003–1006

    Title translation Redução no Número de Pacientes com Síndrome Coronariana Aguda Suspeita e Confirmada nos Primeiros Meses da Pandemia da Covid-19: Análise de uma Rede Brasileira.
    MeSH term(s) Acute Coronary Syndrome/diagnosis ; Acute Coronary Syndrome/epidemiology ; Brazil/epidemiology ; COVID-19 ; Humans ; Pandemics ; SARS-CoV-2
    Language Portuguese
    Publishing date 2021-05-17
    Publishing country Brazil
    Document type Letter
    ZDB-ID 730261-7
    ISSN 1678-4170 ; 0066-782X
    ISSN (online) 1678-4170
    ISSN 0066-782X
    DOI 10.36660/abc.20200873
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Selective atrial vagal denervation guided by spectral mapping to treat advanced atrioventricular block.

    Rivarola, Esteban / Hardy, Carina / Sosa, Eduardo / Hachul, Denise / Furlan, Valter / Raimundi, Fabrizio / Scanavacca, Mauricio

    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology

    2016  Volume 18, Issue 3, Page(s) 445–449

    Abstract: Aims: Asymptomatic nocturnal long ventricular pauses are usually detected accidentally and it has been suggested that they may lead to sudden death. Identification of predisposing factors could prevent cardiovascular events.: Methods and results: We ... ...

    Abstract Aims: Asymptomatic nocturnal long ventricular pauses are usually detected accidentally and it has been suggested that they may lead to sudden death. Identification of predisposing factors could prevent cardiovascular events.
    Methods and results: We report the case of a patient with frequent asymptomatic nocturnal ventricular pauses of 3-11 s, characteristic of a vagally mediated atrioventricular (AV) block. Echocardiography, treadmill test, thyroid function test levels, and polysomnogram were normal. In an attempt to reduce the risk, it was decided that an atrial vagal denervation induced by radiofrequency (RF) ablation (cardioneuroablation) could be useful. Spectral mapping was used to localize endocardial vagal innervation in the right and left aspects of the inter-atrial septum, responsible for the sinus node and AV node modulation, and RF pulses were applied in those sites only. After finishing the procedure, significant changes were observed in the heart rate (66-90 b.p.m.), atrial-His interval (115-74 ms), Wenckebach cycle length (820-570 ms), and sinus node recovery time (1100-760 ms). Follow-up Holter recording demonstrated that the number of ventricular pauses had reduced from 438 to 0. Heart rate and time domain characteristics were compatible with vagal denervation.
    Conclusion: Ablation of the endocardial vagal innervation sites seems to be safe and efficient in reducing the frequency and the length of the ventricular pauses. It was possible by identifying certain spectral components of the atrial electrogram, resulting in a conservative approach.
    MeSH term(s) Action Potentials ; Adult ; Atrioventricular Block/diagnosis ; Atrioventricular Block/physiopathology ; Atrioventricular Block/surgery ; Catheter Ablation ; Electrocardiography, Ambulatory ; Electrophysiologic Techniques, Cardiac ; Endocardium/innervation ; Heart Atria/innervation ; Heart Rate ; Humans ; Male ; Predictive Value of Tests ; Signal Processing, Computer-Assisted ; Time Factors ; Treatment Outcome ; Vagotomy/methods ; Vagus Nerve/physiopathology ; Vagus Nerve/surgery
    Language English
    Publishing date 2016-03
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 1449879-0
    ISSN 1532-2092 ; 1099-5129
    ISSN (online) 1532-2092
    ISSN 1099-5129
    DOI 10.1093/europace/euv142
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Acute Coronary Syndrome After Ondansetron Administration in a Pregnant Woman: Kounis Syndrome?

    Custódio, Juliano Valente / Guimarães, Patrícia O / Tonin, Marina H L / Sampaio, Márcio Campos / Malafaia, Felipe Lopes / de Souza Brito, Flávio / de Barros E Silva, Pedro Gabriel Melo / Furlan, Valter

    JACC. Case reports

    2020  Volume 2, Issue 1, Page(s) 6–8

    Abstract: We report on a pregnant woman with acute coronary syndrome probably caused by an allergic reaction to ondansetron. It also discusses the pathophysiology, main allergic triggers, clinical presentation, and management of Kounis syndrome. ( ...

    Abstract We report on a pregnant woman with acute coronary syndrome probably caused by an allergic reaction to ondansetron. It also discusses the pathophysiology, main allergic triggers, clinical presentation, and management of Kounis syndrome. (
    Language English
    Publishing date 2020-01-15
    Publishing country Netherlands
    Document type Case Reports
    ISSN 2666-0849
    ISSN (online) 2666-0849
    DOI 10.1016/j.jaccas.2019.11.051
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Atypical chest pain due to multiple coronary arteries fistulas occluded with percutaneous interlock coils: A case report.

    Iacomini Ida, Gustavo / Kalansky, Michel A / Baptista, Luciana de Pádua S / de Barros E Silva, Pedro Gabriel Melo / Jamus, Marcelo / Teixeira Garcia, José Carlos / Furlan, Valter / Ribeiro, Expedito E / Ribeiro, Henrique B

    Journal of cardiology cases

    2020  Volume 23, Issue 1, Page(s) 16–19

    Abstract: Coronary artery fistulas, although rare, should be included in the differential diagnosis of atypical chest pain, generally unveiled by cardiac catheterization or multidetector computed tomography. Such anatomical findings in conjunction with detectable ... ...

    Abstract Coronary artery fistulas, although rare, should be included in the differential diagnosis of atypical chest pain, generally unveiled by cardiac catheterization or multidetector computed tomography. Such anatomical findings in conjunction with detectable ischemia and severe symptoms should prompt their closure. Transcatheter closure of fistulas is an attractive alternative to surgery, especially with the novel devices such as the interlock fibered detachable coils, which can be safely and effectively performed in a variety of circumstances, including the coronary arteries with tortuous anatomies. We present a case of atypical chest pain and large burden of ischemia in the stress scintigraphy, due to multiple coronary fistulas to the bronchial arteries successfully occluded with percutaneous interlock coils. <
    Language English
    Publishing date 2020-09-11
    Publishing country Japan
    Document type Case Reports
    ISSN 1878-5409
    ISSN (online) 1878-5409
    DOI 10.1016/j.jccase.2020.08.009
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  9. Article ; Online: Safe and effective protocol for discharge 3 days after cardiac surgery.

    Mejia, Omar Asdrúbal Vilca / Borgomoni, Gabrielle Barbosa / Lasta, Nilza / Okada, Mariana Yumi / Gomes, Mariana Silva Biason / Foz, Mary Lee Norris Nelsen / Bischoff, Helga Priscila Giugno / Saruhashi, Tatiana / Melro, Livia Maria Garcia / Sampaio, Márcio Campos / de Barros E Silva, Pedro Gabriel Melo / Garcia, José Carlos Teixeira / Furlan, Valter

    Scientific reports

    2021  Volume 11, Issue 1, Page(s) 8979

    Abstract: The Enhanced Recovery After Surgery (ERAS) protocol affected traditional cardiac surgery processes and COVID-19 is expected to accelerate its scalability. The aim of this study was to assess the impact of an ERAS-based protocol on the length of hospital ... ...

    Abstract The Enhanced Recovery After Surgery (ERAS) protocol affected traditional cardiac surgery processes and COVID-19 is expected to accelerate its scalability. The aim of this study was to assess the impact of an ERAS-based protocol on the length of hospital stay after cardiac surgery. From January 2019 to June 2020, 664 patients underwent consecutive cardiac surgery at a Latin American center. Here, 46 patients were prepared for a rapid recovery through a multidisciplinary institutional protocol based on the ERAS concept, the "TotalCor protocol". After the propensity score matching, 46 patients from the entire population were adjusted for 12 variables. Patients operated on the TotalCor protocol had reduced intensive care unit time (P < 0.025), postoperative stay (P ≤ 0.001) and length of hospital stay (P ≤ 0.001). In addition, there were no significant differences in the occurrence of complications and death between the two groups. Of the 10-central metrics of TotalCor protocol, 6 had > 70% adherences. In conclusion, the TotalCor protocol was safe and effective for a 3-day discharge after cardiac surgery. Postoperative atrial fibrillation and renal failure were predictors of postoperative stay > 5 days.
    MeSH term(s) Cardiac Surgical Procedures/adverse effects ; Enhanced Recovery After Surgery ; Guideline Adherence ; Humans ; Length of Stay ; Patient Care Team ; Patient Discharge ; Patient Safety ; Postoperative Complications ; Propensity Score
    Language English
    Publishing date 2021-04-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-021-88582-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Electrical cardioversion for supraventricular arrhythmias in octagenarians.

    Malafaia, Felipe L / Guimarães, Patrícia O / Sampaio, Márcio C / de Barros E Silva, Pedro G M / Lopes, Renato D / Custódio, Juliano V / da S Diniz, Miguel / Garcia, José C T / Furlan, Valter

    Journal of geriatric cardiology : JGC

    2019  Volume 16, Issue 12, Page(s) 902–904

    Language English
    Publishing date 2019-12-04
    Publishing country China
    Document type Journal Article
    ZDB-ID 2421391-3
    ISSN 1671-5411
    ISSN 1671-5411
    DOI 10.11909/j.issn.1671-5411.2019.12.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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