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  1. Book ; Thesis: Monotherapie mit Interferon alpha und Kombinationstherapie mit Interferon alpha und Ribavirin bei chronischer Hepatitis-C-Infektion

    Götzberger, Manuela

    2002  

    Author's details vorgelegt von Manuela Götzberger
    Language German
    Size 93 S., graph. Darst., 21 cm
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis München, Univ., Diss., 2002
    HBZ-ID HT013428142
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

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    2002 D 2793 order for loan Magazin

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  2. Article: Technical feasibility and clinical success of direct "free hand" EUS-guided gastroenterostomy in patients with gastric outlet obstruction.

    Fischer, Hanna / Rüther, Katharina / Abdelhafez, Mohamed / Götzberger, Manuela / Dollhopf, Markus / Schlag, Christoph

    Endoscopy international open

    2022  Volume 10, Issue 10, Page(s) E1358–E1363

    Abstract: Background and study ... ...

    Abstract Background and study aims
    Language English
    Publishing date 2022-10-17
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2761052-4
    ISSN 2196-9736 ; 2364-3722
    ISSN (online) 2196-9736
    ISSN 2364-3722
    DOI 10.1055/a-1907-5393
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Akute Cholezystitis bei hohem OP-Risiko: sonografische und endoskopische Therapieoptionen.

    Götzberger, Manuela / Nüssler, Natascha / Braden, Barbara / Dietrich, Christoph F / Müller, Thomas

    Zeitschrift fur Gastroenterologie

    2021  Volume 59, Issue 9, Page(s) 983–990

    Abstract: Cholecystectomy is the gold standard in the treatment of acute cholecystitis, but has a significantly increased risk in multimorbid patients or in the severe course of acute cholecystitis. In such cases, drainage of the damaged gallbladder in combination ...

    Title translation Acute Cholecystitis in high-risk surgical patients: sonographic and endoscopic treatment options.
    Abstract Cholecystectomy is the gold standard in the treatment of acute cholecystitis, but has a significantly increased risk in multimorbid patients or in the severe course of acute cholecystitis. In such cases, drainage of the damaged gallbladder in combination with antibiotic therapy may be superior to primary surgery. The drainage can either be performed as sonographically guided percutaneous transhepatic gallbladder drainage or as EUS-guided transmural stent placement or endoscopic-transpapillary gallbladder drainage. These minimally invasive alternatives to cholecystectomy can be used both as long-term therapy for permanently inoperable patients and temporarily for patients in whom the cholecystectomy is intended after improvement of the general condition. In this overview, the various drainage methods are discussed with regard to technical requirements, immediate and long-term clinical results and complications. With advances in stent design, EUS-guided transmural stent placement from the stomach or duodenum into the gallbladder is becoming the preferred method of gallbladder drainage in centers with the appropriate expertise.
    MeSH term(s) Cholecystitis, Acute/diagnostic imaging ; Cholecystitis, Acute/surgery ; Drainage ; Endoscopy ; Endosonography ; Humans ; Stents ; Treatment Outcome
    Language German
    Publishing date 2021-09-10
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 201387-3
    ISSN 1439-7803 ; 0172-8504 ; 0044-2771
    ISSN (online) 1439-7803
    ISSN 0172-8504 ; 0044-2771
    DOI 10.1055/a-1540-8019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: SOP Endosonografiegesteuerte Gallenwegeingriffe

    Herrmann, Simon / Götzberger, Manuela / Dollhopf, Markus

    Gastroenterologie up2date

    2020  Volume 16, Issue 04, Page(s) 313–322

    Keywords interventionelle Endosonografie (EUS) ; Hepatikogastrostomie ; Choledochoduodenostomie ; EUS-gesteuerte biliäre Drainage (EUS-BD) ; EUS-gesteuerte Gallenwegeingriffe
    Language German
    Publishing date 2020-12-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2203033-5
    ISSN 1616-9727 ; 1616-9670
    ISSN (online) 1616-9727
    ISSN 1616-9670
    DOI 10.1055/a-1083-3796
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  5. Article: Technical feasibility and clinical success of direct “free hand” EUS-guided gastroenterostomy in patients with gastric outlet obstruction

    Fischer, Hanna / Rüther, Katharina / Abdelhafez, Mohamed / Götzberger, Manuela / Dollhopf, Markus / Schlag, Christoph

    Endoscopy International Open

    2022  Volume 10, Issue 10, Page(s) E1358–E1363

    Abstract: Background and study aims : Endoscopic ultrasound-guided gastroenterostomy (EUS-GE) with lumen-apposing metal stents (LAMS) appears to be a promising intervention in management of gastroduodenal out obstruction (GOO), particularly for patients for whom ... ...

    Abstract Background and study aims : Endoscopic ultrasound-guided gastroenterostomy (EUS-GE) with lumen-apposing metal stents (LAMS) appears to be a promising intervention in management of gastroduodenal out obstruction (GOO), particularly for patients for whom surgery is high risk or in a palliative setting. This study aimed to evaluate the technical feasibility, procedure-associated adverse events (AEs), and clinical outcome of direct “free hand” EUS-GE.
    Patients and methods : This retrospective two-center study included patients who underwent direct “free hand” EUS-GE (April 2017 to March 2021) investigating technical success (correctly placed LAMS), clinical outcome (successful oral nutrition), and management of procedure-associated AEs. “Free hand” was defined as the use of the electrocautery enhanced stent delivery system alone without additional guidewire-assistance for EUS-GE creation.
    Results : Forty-five patients (58 % women/42 % men; mean age 65 years) with malignant (n = 39), benign (n = 4) or unclear (n = 2) GOO underwent direct “free hand” EUS-GE. The technical success rate was 98 % (44/45). Of the patients, 95% (42/44) had less vomiting and increased ability to tolerate oral food intake after the intervention. In one patient, a second EUS-GE was necessary to achieve sufficient clinical improvement. Procedure-associated AEs were observed in 24 % (11/45) of cases including stent misplacement (n = 7), leakage (n = 1), development of a gastrojejunocolic fistula (n = 1), and bleeding (n = 2), which could be all managed endoscopically.
    Conclusions : Direct EUS-GE has a favorable risk-benefit profile for patients with GOO, showing high technical success rates, manageable AEs, and rapid symptom relief.
    Language English
    Publishing date 2022-07-22
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2761052-4
    ISSN 2196-9736 ; 2364-3722 ; 2196-9736
    ISSN (online) 2196-9736
    ISSN 2364-3722 ; 2196-9736
    DOI 10.1055/a-1907-5393
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  6. Article ; Online: Comments and illustrations of the WFUMB CEUS liver guidelines: Rare malignant hematological liver lesions.

    Safai Zadeh, Ehsan / Görg, Christian / Huber, Katharina Paulina / Dirks, Klaus / Jenssen, Christian / Lim, Adrian / Möller, Kathleen / Götzberger, Manuela / Dong, Yi / Cui, Xin Wu / Fetzer, David T / Klinger, Christoph / Clevert, Dirk Andre / Dietrich, Christoph F

    Medical ultrasonography

    2023  

    Abstract: Diagnosing rare hematological malignancies in the liver is often challenging owing to their infrequency, and confirmation generally necessitates histological examination. Due to the rarity of these lesions, there are limited data concerning their ... ...

    Abstract Diagnosing rare hematological malignancies in the liver is often challenging owing to their infrequency, and confirmation generally necessitates histological examination. Due to the rarity of these lesions, there are limited data concerning their appearance on ultrasound and, specifically, contrast-enhanced ultrasound. In this review, we describe the pathological and ultrasound features of several hematological malignant liver lesions, including lymphoma of the liver and chloroma. Furthermore, two specific forms of liver lymphoma are described: mucosa-associated lymphoid tissue (MALT) lymphoma andplasmacytoma of the liver.
    Language English
    Publishing date 2023-12-10
    Publishing country Romania
    Document type Journal Article ; Review
    ZDB-ID 2529606-1
    ISSN 2066-8643 ; 1844-4172
    ISSN (online) 2066-8643
    ISSN 1844-4172
    DOI 10.11152/mu-4305
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Einlage eines selbstexpandierenden Ösophagus-Metallstents – Schritt für Schritt

    Scheerer, Frank / Götzberger, Manuela / Dollhopf, Markus

    Gastroenterologie up2date

    2019  Volume 15, Issue 01, Page(s) 17–22

    Keywords Ösophagusstent ; selbstexpandierende Metallstents ; Stenteinlage ; Ösophagusstenose ; Indikationen
    Language German
    Publishing date 2019-03-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2203033-5
    ISSN 1616-9727 ; 1616-9670
    ISSN (online) 1616-9727
    ISSN 1616-9670
    DOI 10.1055/a-0638-6715
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    Zs.A 6474: Show issues Location:
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  8. Article ; Online: A structured Endoscopic Ultrasound training program in Germany improves knowledge and competence.

    Götzberger, Manuela / Kaiser, Christoph / Jenssen, Christian / Dollhopf, Markus / Faiss, Siegbert / Burmester, Eike / Schöppe, Franziska / Gülberg, Veit / Fischer, Martin R

    Medical ultrasonography

    2021  Volume 23, Issue 4, Page(s) 396–401

    Abstract: Aims: Limited evidence on how to organize pre-patient training in Endoscopic Ultrasound (EUS) and how to evaluate its effect on knowledge and skills are available. The aim of our study was to assess the impact of a structured multi-site training program ...

    Abstract Aims: Limited evidence on how to organize pre-patient training in Endoscopic Ultrasound (EUS) and how to evaluate its effect on knowledge and skills are available. The aim of our study was to assess the impact of a structured multi-site training program on EUS competence in Germany.
    Material and methods: In a prospective study design, evaluation of 64 trainees was conducted during four three-day training courses with equal curricula at three sites. Participants completed a structured pre- and post-test questionnaire consisting of 4 items to evaluate the relevance and acceptance of the training components (theoretical teaching, video sessions, live demonstration, hands-on experience) on a 5-point Likert scale, as well as a Likert scale to judge the self-rated improvement in EUS competence. To assess knowledge, 12 multiple choice (MC) questions had to be answered by all participants in a pre- and a post-test design. Also differences between beginners and advanced learners were analysed.
    Results: Overall evaluation on acceptance received above-average results with a median of 4 or 5 (IQR 1-2) on Likert scale (1=completely disagree, 5=completely agree). In the post-test self-rated EUS skills improved from 4 to 2 on the Likert scale (IQR=1, p=0.001, 1=excellent EUS skills, 5=no EUS skills). Results of the MC-test of all trainees showed significant improvement in theoretical knowledge from 7.9±1.9 to 8.8±1.9 points (mean±SD, p=0.001).
    Conclusions: Our study provides arguments for the usefulness of a structured EUS training program resulting in a positive acceptance and high self-rated EUS competence by the participants and significant improvements in knowledge.
    MeSH term(s) Clinical Competence ; Curriculum ; Endosonography ; Germany ; Humans ; Prospective Studies
    Language English
    Publishing date 2021-06-10
    Publishing country Romania
    Document type Journal Article
    ZDB-ID 2529606-1
    ISSN 2066-8643 ; 1844-4172
    ISSN (online) 2066-8643
    ISSN 1844-4172
    DOI 10.11152/mu-2892
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  9. Article: Akute Cholezystitis bei hohem OP-Risiko: sonografische und endoskopische Therapieoptionen

    Götzberger, Manuela / Nüssler, Natascha / Braden, Barbara / Dietrich, Christoph F. / Müller, Thomas

    Zeitschrift für Gastroenterologie

    2021  Volume 59, Issue 09, Page(s) 983–990

    Abstract: Die Cholezystektomie ist der Goldstandard in der Behandlung der akuten Cholezystitis, hat aber bei multimorbiden Patienten oder bei schwerem Verlauf der akuten Cholezystitis ein deutlich erhöhtes OP-Risiko. In solchen Fällen kann eine Drainage der ... ...

    Abstract Die Cholezystektomie ist der Goldstandard in der Behandlung der akuten Cholezystitis, hat aber bei multimorbiden Patienten oder bei schwerem Verlauf der akuten Cholezystitis ein deutlich erhöhtes OP-Risiko. In solchen Fällen kann eine Drainage der entzündeten Gallenblase in Kombination mit antibiotischer Therapie der primären Operation überlegen sein. Die Drainage kann entweder als sonografisch geführte perkutan transhepatische Gallenblasendrainage, als EUS-geführte transmurale Stentplatzierung oder endoskopisch-transpapilläre Gallenblasendrainage erfolgen. Diese minimalinvasiven Alternativen zur Cholezystektomie können sowohl als Langzeittherapie bei dauerhaft inoperablen Patienten als auch vorübergehend bei Patienten eingesetzt werden, bei denen die Cholezystektomie nach Verbesserung des Allgemeinzustands angestrebt wird. In dieser Übersicht werden die verschiedenen Drainagemethoden im Hinblick auf technische Anforderungen sowie klinische Sofort- und Langzeitergebnisse und Komplikationen diskutiert. Mit Fortschritten im Stentdesign entwickelt sich die EUS-geführte transmurale Stentplatzierung von Magen oder Duodenum in die Gallenblase zur bevorzugten Methode der Gallenblasendrainage in Zentren mit entsprechender Expertise.
    Keywords Leitlinie ; interventioneller Ultraschall ; Drainage ; Punktion ; akute Cholezystitis ; Endosonografie ; guideline ; interventional ultrasound ; drainage ; puncture ; acute cholecystitis ; endoscopic ultrasound
    Language German
    Publishing date 2021-09-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 201387-3
    ISSN 1439-7803 ; 0044-2771 ; 0172-8504
    ISSN (online) 1439-7803
    ISSN 0044-2771 ; 0172-8504
    DOI 10.1055/a-1540-8019
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  10. Article ; Online: Comments and illustrations of the WFUMB CEUS liver guidelines: Rare focal liver lesions - infectious (bacterial).

    Ignee, André / Möller, Kathleen / Thees-Laurenz, Ruth / Zadeh, Ehsan Safai / Görg, Christian / Correas, Jean Michel / Chaubal, Nitin / Sansone, Vito / Jenssen, Christian / Dong, Yi / Götzberger, Manuela / Meloni, Maria Franca / Cui, Xin Wu / Klinger, Christoph / DeMolo, Chiara / Carla, Serra / Lim, Adrian / Huang, Pintong / Espinosa Montagut, Nathally /
    Dietrich, Christoph Frank

    Medical ultrasonography

    2023  Volume 25, Issue 3, Page(s) 312–324

    Abstract: In this series of papers on comments and illustrations of the World Federation for Medicine and Biology (WFUMB) guidelines on contrast enhanced ultrasound (CEUS) the topics of bacterial infections are discussed. Improved detection and characterization of ...

    Abstract In this series of papers on comments and illustrations of the World Federation for Medicine and Biology (WFUMB) guidelines on contrast enhanced ultrasound (CEUS) the topics of bacterial infections are discussed. Improved detection and characterization of common focal liver lesions (FLL) are the main topics of these guidelines but detailed and illustrating information is missing. The focus in this paper on infectious (bacterial) focal liver lesions is on their appearance on B-mode and Doppler ultrasound and CEUS features. Knowledge of these data should help to raise awareness of these rarer findings, to think of these clinical pictures in the corresponding clinical situation, to interpret the ultrasound images correctly and thus to initiate the appropriate diagnostic and therapeutic steps in time.
    MeSH term(s) Humans ; Liver Neoplasms/pathology ; Contrast Media ; Liver/diagnostic imaging ; Liver/pathology ; Ultrasonography/methods ; Angiography
    Chemical Substances Contrast Media
    Language English
    Publishing date 2023-03-14
    Publishing country Romania
    Document type Journal Article ; Review
    ZDB-ID 2529606-1
    ISSN 2066-8643 ; 1844-4172
    ISSN (online) 2066-8643
    ISSN 1844-4172
    DOI 10.11152/mu-4065
    Database MEDical Literature Analysis and Retrieval System OnLINE

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