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  1. Article ; Online: Delir im Aufwachraum – Frühes Erkennen ermöglicht zügiges Handeln.

    Günther, Ulf

    Die Anaesthesiologie

    2023  Volume 72, Issue 7, Page(s) 457–458

    Title translation Delirium in the postanesthesia recovery room-Early recognition enables swift action.
    MeSH term(s) Animals ; Recovery Room ; Delirium ; Postoperative Complications ; Birds
    Language German
    Publishing date 2023-07-05
    Publishing country Germany
    Document type Editorial
    ISSN 2731-6866
    ISSN (online) 2731-6866
    DOI 10.1007/s00101-023-01290-4
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  2. Book ; Thesis: Untersuchung von vier Varianten der stabilen Seitenlage auf Durchblutungseinschränkungen und subjektive Beschwerden im unten liegenden Arm

    Guenther, Ulf

    2000  

    Author's details vorgelegt von Ulf Guenther
    Language German
    Size 86 Bl. : Ill., graph. Darst.
    Edition [Mikrofiche-Ausg.]
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Göttingen, Univ., Diss., 2002
    HBZ-ID HT013549509
    Database Catalogue ZB MED Medicine, Health

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  3. Article ; Online: Gründe für die Nichtteilnahme an einer Patientenbefragung im Kontext der prähospitalen Notfallversorgung durch Gemeindenotfallsanitäter - eine retrospektive Beobachtungsstudie.

    Seeger, Insa / Klausen, Andrea Diana / Günther, Ulf / Bienzeisler, Jonas / Schnack, Helge / Lubasch, Johanna Sophie

    Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen

    2024  

    Abstract: Background: In order to evaluate whether the new rescue means "community emergency paramedics" (Gemeindenotfallsanitäter [G-NFS]) relieves the emergency medical service (EMS) in the care of low-priority emergencies, the perspective of general ... ...

    Title translation Reasons for non-participation in a patient survey in the context of prehospital emergency medical care by community emergency paramedics - A retrospective observational study.
    Abstract Background: In order to evaluate whether the new rescue means "community emergency paramedics" (Gemeindenotfallsanitäter [G-NFS]) relieves the emergency medical service (EMS) in the care of low-priority emergencies, the perspective of general practitioners and patients was also surveyed in a written questionnaire as part of an innovation fund project. Recruitment for participation in the study proved to be difficult. The aim of this study is to evaluate why the G-NFS decided against providing information on study participation and what measures would be necessary to include more emergency patients in surveys in the future.
    Methods: Retrospective analysis of the assignment protocols from April 1, 2021 to June 30, 2022. In addition to patient characteristics, data on treatments, interventions and recommendations to patients as well as reasons for non-participation in the patient survey were collected.
    Results: 5,395 G-NFS protocols that contained information on non-participation were included in the analysis. The average age of the patients was 62.4 years (SD 22.7), and 50.2% were female. 57.4% of the cases were categorised as non-urgent, and 35.2% of the cases required an additional ambulance to be alerted. 404 (7.5%) patients used the EMS more than once, 1,120 (20.8%) did not have sufficient language skills, 1,012 (18.8%) patients declined study participation, and 2,975 (55.1%) patients were not able to participate according to the G-NFS assessment. Dementia/neurocognitive impairment (35%), acute/emergency situation (26.5%), mental health impairment (10.3%), and substance abuse (6.5%) were given as reasons for non-participation from the G-NFS perspective.
    Discussion: The results show that more than half of the patients were unable to take part in a written survey for various reasons, even though there was no need for urgent care. This could be due to a high demand for care and the complex consent procedure. In addition, further resources are required to provide needs-based care for these patients in order to relieve the burden on emergency medical care. Over half of the patients were unable to take part in a written survey for various reasons. Further research is needed to determine what consent procedures are appropriate to facilitate patients' study participation.
    Language German
    Publishing date 2024-04-22
    Publishing country Netherlands
    Document type English Abstract ; Journal Article
    ZDB-ID 2412512-X
    ISSN 2212-0289 ; 1865-9217
    ISSN (online) 2212-0289
    ISSN 1865-9217
    DOI 10.1016/j.zefq.2024.03.007
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  4. Article: Orientiert, desorientiert, verwirrt? Was ist bei der Delirdiagnostik wichtig?

    Günther, Ulf / Hansen, Hans-Christian

    DIVI

    2022  Volume 13, Issue 3, Page(s) 152

    Language German
    Document type Article
    ZDB-ID 2544349-5
    ISSN 1869-716X
    Database Current Contents Medicine

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  5. Article ; Online: Versorgung älterer Patienten durch Gemeindenotfallsanitäter : Vergleich der Einsätze im Pflegeheim und in der Häuslichkeit.

    Seeger, Insa / Günther, Ulf / Schmiemann, Guido / Hoffmann, Falk

    Medizinische Klinik, Intensivmedizin und Notfallmedizin

    2021  Volume 117, Issue 7, Page(s) 542–548

    Abstract: Background: Emergency departments and emergency services are increasingly burdened by non-emergency patients. A substantial proportion of these is represented by older people. The project "community emergency paramedic" ("Gemeindenotfallsanitäter" [G- ... ...

    Title translation Care of older patients by community emergency paramedics : Comparison of community-dwellers and nursing home residents.
    Abstract Background: Emergency departments and emergency services are increasingly burdened by non-emergency patients. A substantial proportion of these is represented by older people. The project "community emergency paramedic" ("Gemeindenotfallsanitäter" [G-NFS]) was initiated to prevent unnecessary use of emergency services.
    Objective: To identify specific utilizations of the G‑NFS services by older people at home and in nursing homes.
    Material and methods: Retrospective analysis of the assignment protocols from July 2019 through June 2020. Only data from patients aged ≥ 65 years were included. Data were grouped into whether patients lived on their own or in nursing homes.
    Results: A total of 2358 protocols of older patients (mean age 80.8 years; 52.9% female) were evaluated and 55% of patients were treated on-site. The most frequently used measures by G‑NFS were counselling (79.4%), aid in self-medication (16.7%) and administration of medication (23.2%). Of the G‑NFS assignments 329 (14.0%) were carried out for nursing home residents. Measures related to urine catheter complications were more frequently performed in nursing home residents than in patients who lived at home (32.2% vs. 5.7%). Compared to other emergency cases, patients with catheter-related complications were most often treated at the scene (84.3% vs. 52.2%).
    Conclusion: The G‑NFS enabled the majority of patients to be treated on-site, thus saving resources of emergency services and hospitals; however, the G‑NFS also performed measures that were normally the responsibility of general practitioners. This possibly highlights structural deficits in the medical and nursing care of older people.
    MeSH term(s) Aged ; Aged, 80 and over ; Emergency Medical Services ; Emergency Medical Technicians ; Female ; Humans ; Male ; Nursing Homes ; Retrospective Studies
    Language German
    Publishing date 2021-09-16
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2636018-4
    ISSN 2193-6226 ; 1435-1420 ; 0723-5003 ; 2193-6218 ; 0175-3851
    ISSN (online) 2193-6226 ; 1435-1420
    ISSN 0723-5003 ; 2193-6218 ; 0175-3851
    DOI 10.1007/s00063-021-00863-8
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  6. Article ; Online: Handlungsalgorithmus: Agitation bei kritisch kranken Patienten.

    Nydahl, Peter / Baum, Sebastian / Dayton, Kali / Günther, Ulf / Hansen, Hans Christian

    Medizinische Klinik, Intensivmedizin und Notfallmedizin

    2023  Volume 118, Issue 8, Page(s) 660–662

    Title translation Treatment algorithm: agitation in critically ill patients.
    MeSH term(s) Humans ; Critical Illness/therapy ; Anxiety ; Critical Care ; Algorithms ; Psychomotor Agitation/therapy
    Language German
    Publishing date 2023-09-11
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2636018-4
    ISSN 2193-6226 ; 1435-1420 ; 0723-5003 ; 2193-6218 ; 0175-3851
    ISSN (online) 2193-6226 ; 1435-1420
    ISSN 0723-5003 ; 2193-6218 ; 0175-3851
    DOI 10.1007/s00063-023-01066-z
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  7. Article ; Online: Häufigkeit und Charakteristika von Einsätzen der Gemeindenotfallsanitäter bei Pflegebedürftigen : Analyse von 2410 Einsatzprotokollen bei Personen im Alter von 65+ Jahren.

    Klausen, Andrea Diana / Günther, Ulf / Schmiemann, Guido / Hoffmann, Falk / Seeger, Insa

    Medizinische Klinik, Intensivmedizin und Notfallmedizin

    2023  Volume 119, Issue 4, Page(s) 316–322

    Abstract: Background: The aim of this study was to obtain a differentiated view of interventions delivered by community paramedics (Gemeindenotfallsanitäter, G‑NFS) in older people in need of care living in nursing homes and at home.: Materials and methods: A ... ...

    Title translation Frequency and characteristics of interventions by community paramedics on people in need of care : Analysis of 2,410 deployment protocols for people aged 65+ years.
    Abstract Background: The aim of this study was to obtain a differentiated view of interventions delivered by community paramedics (Gemeindenotfallsanitäter, G‑NFS) in older people in need of care living in nursing homes and at home.
    Materials and methods: A retrospective analysis of G‑NFS documentation from 2021 with a focus on patients aged ≥65 years was performed. Data were grouped into callouts to nursing homes or private homes. Interventions, urgency, transport, and further recommendations were analyzed descriptively.
    Results: Of 5,900 G-NFS protocols, 43.0% (n = 2,410) were related to elderly people (mean age 80.8 years, 49.7% female). A total of 20.6% of these callouts involved nursing home residents, 38.4% (n = 926) were homecare patients, and 41% (n = 988) of callouts were to persons who did not rely on care. No specific interventions except advice were given to 48.4% of nursing home residents, and to even 82.1% of those in homecare and 83.7% of those without care needs. About 60% of the G‑NFS interventions were classified as non-urgent. Transport was waived for 63.1% of nursing home residents, for 58.1% in homecare, and for 60.6% of persons without care needs. A visit to the emergency department was recommended to 29.4% of nursing home residents, 37.6% of homecare patients, and 33.6% of persons without need of care. Measures related to urine catheters were documented much more often in nursing homes (38.5%) than in patients in homecare (15.1%) or without need of care (9.3%).
    Conclusion: Community paramedics perform primary care tasks and can contribute to a reduction in unnecessary transport. It should be discussed whether the emergency medical service is responsible for such interventions and how older people in need of care can be cared for according to their needs in the future.
    MeSH term(s) Humans ; Aged ; Nursing Homes ; Female ; Male ; Aged, 80 and over ; Retrospective Studies ; Germany ; Homes for the Aged ; Home Care Services ; Emergency Medical Services ; Health Services Needs and Demand ; Transportation of Patients ; Emergency Medical Technicians ; Allied Health Personnel ; Utilization Review ; Paramedics
    Language German
    Publishing date 2023-12-06
    Publishing country Germany
    Document type English Abstract ; Journal Article
    ZDB-ID 2636018-4
    ISSN 2193-6226 ; 1435-1420 ; 0723-5003 ; 2193-6218 ; 0175-3851
    ISSN (online) 2193-6226 ; 1435-1420
    ISSN 0723-5003 ; 2193-6218 ; 0175-3851
    DOI 10.1007/s00063-023-01085-w
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  8. Article: A helicase links upstream ORFs and RNA structure

    Jankowsky, Eckhard / Guenther, Ulf-Peter

    Current genetics. 2019 Apr., v. 65, no. 2

    2019  

    Abstract: Upstream open reading frames (uORFs) in 5′ UTRs of eukaryotic mRNAs are increasingly recognized as important elements that regulate cellular protein synthesis. Since uORFs can start from non-AUG codons, an enormous number of potential uORF initiation ... ...

    Abstract Upstream open reading frames (uORFs) in 5′ UTRs of eukaryotic mRNAs are increasingly recognized as important elements that regulate cellular protein synthesis. Since uORFs can start from non-AUG codons, an enormous number of potential uORF initiation sites exists in 5′UTRs. However, only a subset of these sites is used and it has been unclear how actual start sites are selected. Studies of the DEAD-box helicase Ded1p from S. cerevisiae show that translation of uORFs with non-AUG initiation codons occurs upstream of mRNA structures that emerge with defective Ded1p. The data designate mRNA structure as important determinant for non-AUG initiation sites of uORFs. Ded1p can control this RNA structure and thereby regulate uORF translation.
    Keywords codons ; enzymes ; messenger RNA ; open reading frames ; protein synthesis ; translation (genetics)
    Language English
    Dates of publication 2019-04
    Size p. 453-456.
    Publishing place Springer Berlin Heidelberg
    Document type Article
    Note Review
    ZDB-ID 282876-5
    ISSN 1432-0983 ; 0172-8083
    ISSN (online) 1432-0983
    ISSN 0172-8083
    DOI 10.1007/s00294-018-0911-z
    Database NAL-Catalogue (AGRICOLA)

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  9. Article ; Online: A helicase links upstream ORFs and RNA structure.

    Jankowsky, Eckhard / Guenther, Ulf-Peter

    Current genetics

    2018  Volume 65, Issue 2, Page(s) 453–456

    Abstract: Upstream open reading frames (uORFs) in 5' UTRs of eukaryotic mRNAs are increasingly recognized as important elements that regulate cellular protein synthesis. Since uORFs can start from non-AUG codons, an enormous number of potential uORF initiation ... ...

    Abstract Upstream open reading frames (uORFs) in 5' UTRs of eukaryotic mRNAs are increasingly recognized as important elements that regulate cellular protein synthesis. Since uORFs can start from non-AUG codons, an enormous number of potential uORF initiation sites exists in 5'UTRs. However, only a subset of these sites is used and it has been unclear how actual start sites are selected. Studies of the DEAD-box helicase Ded1p from S. cerevisiae show that translation of uORFs with non-AUG initiation codons occurs upstream of mRNA structures that emerge with defective Ded1p. The data designate mRNA structure as important determinant for non-AUG initiation sites of uORFs. Ded1p can control this RNA structure and thereby regulate uORF translation.
    MeSH term(s) 5' Untranslated Regions ; Codon ; DNA Helicases/metabolism ; Gene Expression Regulation, Fungal ; Meiosis/genetics ; Open Reading Frames ; Protein Biosynthesis ; RNA, Messenger/chemistry ; RNA, Messenger/genetics ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism
    Chemical Substances 5' Untranslated Regions ; Codon ; RNA, Messenger ; DNA Helicases (EC 3.6.4.-)
    Language English
    Publishing date 2018-11-27
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 282876-5
    ISSN 1432-0983 ; 0172-8083
    ISSN (online) 1432-0983
    ISSN 0172-8083
    DOI 10.1007/s00294-018-0911-z
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  10. Book ; Online ; Thesis: Die Aktivität der Cholinesterase im Blut als Marker für das Auftreten des postoperativen Delirs bei herzchirurgischen Patient:innen

    Wolke, Mirko [Verfasser] / Günther, Ulf [Akademischer Betreuer]

    2022  

    Author's details Mirko Wolke ; Betreuer: Ulf Günther
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher BIS der Universität Oldenburg
    Publishing place Oldenburg
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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