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Article ; Online: Paradoxical embolic stroke: giant coronary aneurysms, myxoma, and PFO.

Zini, Andrea / Tondi, Stefano / Gabbieri, Davide / Gozzi, Manuela / Fioravanti, Valentina

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

2022 Volume 43, Issue 10, Page(s) 6101–6103

MeSH term(s)	Coronary Aneurysm/complications ; Coronary Aneurysm/diagnostic imaging ; Embolic Stroke ; Embolism, Paradoxical ; Foramen Ovale, Patent/complications ; Foramen Ovale, Patent/diagnostic imaging ; Humans ; Myxoma/complications ; Myxoma/diagnostic imaging ; Stroke/complications ; Stroke/diagnostic imaging
Language	English
Publishing date	2022-05-31
Publishing country	Italy
Document type	Letter
ZDB-ID	2016546-8
ISSN	1590-3478 ; 1590-1874
ISSN (online)	1590-3478
ISSN	1590-1874
DOI	10.1007/s10072-022-06161-1
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Zs.A 1877: Show issues

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Article ; Online: Epilepsy in patients undergoing cardiac surgery with ExtraCorporeal Circulation: case series and description of a peculiar clinical phenotype.

Pugnaghi, Matteo / Cavallieri, Francesco / Zennaro, Mauro / Zedde, Marialuisa / Rizzi, Romana / Gabbieri, Davide / Valzania, Franco

BMC neurology

2022 Volume 22, Issue 1, Page(s) 136

Abstract: Background: Extracorporeal circulation (ECC) is now being increasingly used in critical care settings. Epileptic seizures are a recognized but under reported complication in patients receiving this care. Acute symptomatic post-operative seizures have ... ...

Abstract	Background: Extracorporeal circulation (ECC) is now being increasingly used in critical care settings. Epileptic seizures are a recognized but under reported complication in patients receiving this care. Acute symptomatic post-operative seizures have been described, as well as remote seizure, mostly in the form of convulsive seizures. Epilepsy has also been reported, although with lower frequency and mainly with convulsive seizures, while different seizure semiology is rarely described. Case presentation: We report a case series of four patients developing epilepsy with homogeneous features following heart surgery with ECC. We present neurophysiological and neuroradiological data and we describe the peculiar characteristics of epilepsies in terms of seizure semiology, frequency, and drug response. The main features are: an insulo-temporal or parieto-occipital semiology, often multifocal and without loss of consciousness or motor manifestations, a high frequency of seizures but with low impact on daily life, and a good response to anti-epileptic therapy. Conclusions: We hypothesize a pathogenetic mechanism and we discuss the clinical implications of identifying these forms of epilepsy which tend to be often under-recognized.
MeSH term(s)	Cardiac Surgical Procedures/adverse effects ; Electroencephalography ; Epilepsy/complications ; Epilepsy/surgery ; Extracorporeal Circulation/adverse effects ; Humans ; Phenotype ; Seizures/etiology ; Seizures/surgery
Language	English
Publishing date	2022-04-11
Publishing country	England
Document type	Case Reports ; Journal Article
ZDB-ID	2041347-6
ISSN	1471-2377 ; 1471-2377
ISSN (online)	1471-2377
ISSN	1471-2377
DOI	10.1186/s12883-022-02665-7
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Article: Coronary Revascularization after Transcatheter and Surgical Aortic Valve Replacement.

Gabbieri, Davide / Giorgi, Federico / Mascheroni, Greta / Chiarabelli, Matteo / D'Anniballe, Giuseppe / Meli, Marco / Labia, Clorinda / Ghidoni, Italo

Journal of clinical medicine

2023 Volume 12, Issue 23

Abstract: Introduction: Due to the selective criteria and short-term follow-up of previous transcatheter aortic valve implantation (TAVI) trials, the coronary revascularization incidence after TAVI has been difficult to determine. This study investigated the ... ...

Abstract	Introduction: Due to the selective criteria and short-term follow-up of previous transcatheter aortic valve implantation (TAVI) trials, the coronary revascularization incidence after TAVI has been difficult to determine. This study investigated the epidemiology of coronary revascularization after surgical aortic valve replacement (SAVR) and TAVI in patients with severe aortic valve stenosis (AS), with and without coronary artery disease (CAD), in a mid-term follow-up, single-center, real-world setting. Methods: Between 2010 to 2020, 1486 patients with AS underwent SAVR or TAVI with balloon-expandable Edwards Results: The 5-year overall survival was 78.2%. Freedom from PCI after AVR and TAVI at 5 years was 96.9% and 96.9%, respectively, with previous PCI as a predictor (HR 4.86, 95% CI 2.57-9.21 Conclusions: Notwithstanding the aged population, the revascularization incidence was only 2.4%, requiring further evaluation even in younger patients with longer follow-up. Despite the profile frame raise due to the evolution of Edwards
Language	English
Publishing date	2023-11-23
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm12237257
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Article: Transseptal mitral valve-in-valve implantation helps to elucidate the degree of concomitant aortic valve stenosis.

Sacha, Jerzy / Krawczyk, Krzysztof / Tomaszewski, Paweł / Bugajski, Jarosław / Gawroński, Radosław / Gabbieri, Davide

Postepy w kardiologii interwencyjnej = Advances in interventional cardiology

2020 Volume 16, Issue 4, Page(s) 516–518

Language	English
Publishing date	2020-12-29
Publishing country	Poland
Document type	Journal Article
ISSN	1734-9338
ISSN	1734-9338
DOI	10.5114/aic.2020.101783
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Article ; Online: Trans-catheter valve implantation and patient outcomes: Focus on the kidney.

Boriani, Giuseppe / Arrotti, Salvo / Gabbieri, Davide / Magnavacchi, Paolo / Sgura, Fabio Alfredo

European journal of internal medicine

2020 Volume 83, Page(s) 88–89

MeSH term(s)	Aortic Valve/surgery ; Aortic Valve Stenosis/surgery ; Catheters ; Humans ; Kidney ; Transcatheter Aortic Valve Replacement
Language	English
Publishing date	2020-08-24
Publishing country	Netherlands
Document type	Letter ; Comment
ZDB-ID	1038679-8
ISSN	1879-0828 ; 0953-6205
ISSN (online)	1879-0828
ISSN	0953-6205
DOI	10.1016/j.ejim.2020.08.020
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Zs.A 2608: Show issues

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Article ; Online: Corrigendum to "Risks and Challenges of Surgery for Aortic Prosthetic Valve Endocarditis" [Heart Lung Circ. 27(March (3)) (2018) 333-343].

Grubitzsch, Herko / Tarar, Wajahat / Claus, Benjamin / Gabbieri, Davide / Falk, Volkmar / Christ, Torsten

Heart, lung & circulation

2020 Volume 29, Issue 6, Page(s) e84

Language	English
Publishing date	2020-07-13
Publishing country	Australia
Document type	Journal Article ; Published Erratum
ZDB-ID	2020980-0
ISSN	1444-2892 ; 1443-9506
ISSN (online)	1444-2892
ISSN	1443-9506
DOI	10.1016/j.hlc.2020.05.095
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Zs.A 4988: Show issues

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Article: Quantitative flow ratio-based outcomes in patients undergoing transcatheter aortic valve implantation quaestio study.

Demola, Pierluigi / Colaiori, Iginio / Bosi, Davide / Musto D'Amore, Sergio / Vitolo, Marco / Benatti, Giorgio / Vignali, Luigi / Tadonio, Iacopo / Gabbieri, Davide / Losi, Luciano / Magnavacchi, Paolo / Sgura, Fabio Alfredo / Boriani, Giuseppe / Guiducci, Vincenzo

Frontiers in cardiovascular medicine

2023 Volume 10, Page(s) 1188644

Abstract: Background: Coronary artery disease (CAD) is common in patients with aortic valve stenosis (AS) ranging from 60% to 80%. The clinical and prognostic role of coronary artery lesions in patients undergoing Transcatheter Aortic Valve Implantation (TAVI) ... ...

Abstract	Background: Coronary artery disease (CAD) is common in patients with aortic valve stenosis (AS) ranging from 60% to 80%. The clinical and prognostic role of coronary artery lesions in patients undergoing Transcatheter Aortic Valve Implantation (TAVI) remains unclear. The aim of the present observational study was to estimate long-term clinical outcomes by Quantitative Flow Ratio (QFR) characterization of CAD in a well-represented cohort of patients affected by severe AS treated by TAVI. Methods: A total of 439 invasive coronary angiographies of patients deemed eligible for TAVI by local Heart Teams with symptomatic severe AS were retrospectively screened for QFR analysis. The primary endpoint of the study was all-cause mortality. The secondary endpoint was a composite of cardiovascular mortality, stroke/transient ischemic attack (TIA), acute myocardial infarction (AMI), and any hospitalization after TAVI. Results: After exclusion of patients with no follow-up data, coronary angiography not feasible for QFR analysis and previous surgical myocardial revascularization (CABG) 48/239 (20.1%) patients had a QFR value lower or equal to 0.80 (QFR + value), while the remaining 191/239 (79.9%) did not present any vessel with a QFR positive value. In the adjusted Cox regression analysis, patients with positive QFR were independently associated with an increased risk of all-casual mortality (Model 1, HR 3.47, 95% CI, 2.35-5.12; Model 2, HR 5.01, 95% CI, 3.17-7.90). In the adjusted covariate analysis, QFR+ involving LAD (37/48, 77,1%) was associated with the higher risk of the composite outcome compared to patients without any positive value of QFR or non-LAD QFR positive value (11/48, 22.9%). Conclusions: Pre-TAVI QFR analysis can be used for a safe, simple, wireless functional assessment of CAD. QFR permits to identify patients at high risk of cardiovascular mortality or MACE, and it could be considered by local Heart Teams.
Language	English
Publishing date	2023-08-30
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2781496-8
ISSN	2297-055X
ISSN	2297-055X
DOI	10.3389/fcvm.2023.1188644
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Article ; Online: The Importance of Mehran Score to Predict Acute Kidney Injury in Patients with TAVI: A Large Multicenter Cohort Study.

Arrotti, Salvatore / Sgura, Fabio Alfredo / Monopoli, Daniel Enrique / Siena, Valerio / Leo, Giulio / Morgante, Vernizia / Cataldo, Paolo / Magnavacchi, Paolo / Gabbieri, Davide / Guiducci, Vincenzo / Benatti, Giorgio / Vignali, Luigi / Boriani, Giuseppe / Rossi, Rosario

Journal of cardiovascular development and disease

2023 Volume 10, Issue 6

Abstract: Background: Transcatheter aortic valve implantation (TAVI) has developed as an alternative to surgery for symptomatic high-risk patients with aortic stenosis (AS). An important complication of TAVI is acute kidney injury. The purpose of the study was to ...

Abstract	Background: Transcatheter aortic valve implantation (TAVI) has developed as an alternative to surgery for symptomatic high-risk patients with aortic stenosis (AS). An important complication of TAVI is acute kidney injury. The purpose of the study was to investigate if the Mehran Score (MS) could be used to predict acute kidney injury (AKI) in TAVI patients. Methods: This is a multicenter, retrospective, observational study including 1180 patients with severe AS. The MS comprised eight clinical and procedural variables: hypotension, congestive heart failure class, glomerular filtration rate, diabetes, age >75 years, anemia, need for intra-aortic balloon pump, and contrast agent volume use. We assessed the sensitivity and specificity of the MS in predicting AKI following TAVI, as well as the predictive value of MS with each AKI-related characteristic. Results: Patients were categorized into four risk groups based on MS: low (≤5), moderate (6-10), high (11-15), and very high (≥16). Post-procedural AKI was observed in 139 patients (11.8%). MS classes had a higher risk of AKI in the multivariate analysis (HR 1.38, 95% CI, 1.43-1.63, Conclusions: MS was shown to be a predictor of AKI development in TAVI patients.
Language	English
Publishing date	2023-05-24
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2777082-5
ISSN	2308-3425 ; 2308-3425
ISSN (online)	2308-3425
ISSN	2308-3425
DOI	10.3390/jcdd10060228
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Article: Expert Consensus on Sizing and Positioning of SAPIEN 3/Ultra in Bicuspid Aortic Valves.

Blackman, Daniel / Gabbieri, Davide / Del Blanco, Bruno García / Kempfert, Jörg / Laine, Mika / Mascherbauer, Julia / Parma, Radoslaw / Tchétché, Didier

Cardiology and therapy

2021 Volume 10, Issue 2, Page(s) 277–288

Abstract: Severe aortic stenosis patients with bicuspid anatomy have been excluded from the major transcatheter aortic valve replacement (TAVI) randomized clinical trials. As a result, there is no official recommendation on bicuspid TAVI. A panel of bicuspid ... ...

Abstract	Severe aortic stenosis patients with bicuspid anatomy have been excluded from the major transcatheter aortic valve replacement (TAVI) randomized clinical trials. As a result, there is no official recommendation on bicuspid TAVI. A panel of bicuspid experts was created to fill this gap. In this consensus statement, an algorithm is proposed to guide the choice of surgery or TAVI within this complex patient population, depending on aortic dilatation, age, surgical risk score, and anatomy. A step-by-step guide for sizing and positioning of the SAPIEN 3/Ultra TAVI bioprostheses is presented. Annular sizing remains the primary strategy in most bicuspid patients. However, some anatomies may require sizing at the supra-annular level, for which patients the panel recommends the circle method, a dedicated sizing and positioning approach for SAPIEN 3/Ultra. The consensus provides valuable pre-operative insights on the interactions between SAPIEN 3/Ultra and the bicuspid anatomy; understanding the valve-anatomy relationship is critical to avoid complications and to optimize outcomes for patients.
Language	English
Publishing date	2021-06-03
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2700626-8
ISSN	2193-6544 ; 2193-8261
ISSN (online)	2193-6544
ISSN	2193-8261
DOI	10.1007/s40119-021-00223-9
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Article ; Online: Atrial fibrillation before and after transcatheter aortic valve implantation: short- and long-term clinical implications.

Arrotti, Salvatore / Sgura, Fabio Alfredo / Leo, Giulio / Vitolo, Marco / Monopoli, Daniel / Forzati, Nicola / Siena, Valerio / Menozzi, Matteo / Cataldo, Paolo / Stuani, Marco / Morgante, Vernizia / Magnavacchi, Paolo / Gabbieri, Davide / Guiducci, Vincenzo / Benatti, Giorgio / Vignali, Luigi / Rossi, Rosario / Boriani, Giuseppe

Journal of cardiovascular medicine (Hagerstown, Md.)

2023 Volume 25, Issue 1, Page(s) 51–59

Abstract: Background: Patients with atrial fibrillation (AF) undergoing transcatheter aortic valve implantation (TAVI) have been associated with worse short-term outcomes compared with patients in sinus rhythm but data on long-term outcomes are limited. The aim ... ...

Abstract	Background: Patients with atrial fibrillation (AF) undergoing transcatheter aortic valve implantation (TAVI) have been associated with worse short-term outcomes compared with patients in sinus rhythm but data on long-term outcomes are limited. The aim of our study was to evaluate the association between AF and short- and long-term outcomes in patients undergoing TAVI. Methods: We retrospectively evaluated patients undergoing TAVI between 2012 and 2022 in four tertiary centres. Two different analyses were conducted: (i) in-hospital and (ii) postdischarge analysis. First, we evaluated the association between preexisting AF and short-term outcomes according to VARC-3 criteria. Second, we analyzed the association between AF at discharge (defined as both preexisting and new-onset AF occurring after TAVI) and long-term outcomes at median follow-up of 3.2 years (i.e. all-cause death, hospitalization and major adverse cardiovascular events). Results: A total of 759 patients were initially categorized according to the presence of preexisting AF (241 vs. 518 patients). The preexisting AF group had a higher occurrence of acute kidney injury [odds ratio (OR) 1.65; 95%confidence interval ( CI) 1.15-2.38] and major bleeding (OR 1.86, 95% CI 1.06-3.27). Subsequently, the population was categorized according to the presence of AF at discharge. At the adjusted Cox regression analysis, AF was independently associated with an increased risk of all-cause death and cardiovascular hospitalization [adjusted hazard ratio (aHR) 1.42, 95% CI 1.09-1.86], all-cause death and all-cause hospitalization (aHR 1.38, 95% CI 1.06-1.78) and all-cause hospitalization (aHR 1.59, 95% CI 1.14.2.22). Conclusions: In a real-world cohort of patients undergoing TAVI, the presence of AF (preexisting and new-onset) was independently associated with both short- and long-term adverse outcomes.
MeSH term(s)	Humans ; Atrial Fibrillation/diagnosis ; Atrial Fibrillation/epidemiology ; Atrial Fibrillation/complications ; Transcatheter Aortic Valve Replacement/adverse effects ; Retrospective Studies ; Aftercare ; Aortic Valve Stenosis/diagnostic imaging ; Aortic Valve Stenosis/surgery ; Aortic Valve Stenosis/complications ; Risk Factors ; Patient Discharge ; Aortic Valve/diagnostic imaging ; Aortic Valve/surgery ; Treatment Outcome
Language	English
Publishing date	2023-12-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	2223461-5
ISSN	1558-2035 ; 1558-2027
ISSN (online)	1558-2035
ISSN	1558-2027
DOI	10.2459/JCM.0000000000001553
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Zs.A 5210: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
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