LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 6 of total 6

Search options

  1. Article ; Online: Peritoneal Carcinosis

    Alfonso Reginelli / Giuliana Giacobbe / Maria Teresa Del Canto / Marina Alessandrella / Giovanni Balestrucci / Fabrizio Urraro / Gaetano Maria Russo / Luigi Gallo / Ginevra Danti / Barbara Frittoli / Luca Stoppino / Daria Schettini / Franco Iafrate / Salvatore Cappabianca / Andrea Laghi / Roberto Grassi / Luca Brunese / Antonio Barile / Vittorio Miele

    Diagnostics, Vol 13, Iss 1974, p

    What the Radiologist Needs to Know

    2023  Volume 1974

    Abstract: Peritoneal carcinosis is a condition characterized by the spread of cancer cells to the peritoneum, which is the thin membrane that lines the abdominal cavity. It is a serious condition that can result from many different types of cancer, including ... ...

    Abstract Peritoneal carcinosis is a condition characterized by the spread of cancer cells to the peritoneum, which is the thin membrane that lines the abdominal cavity. It is a serious condition that can result from many different types of cancer, including ovarian, colon, stomach, pancreatic, and appendix cancer. The diagnosis and quantification of lesions in peritoneal carcinosis are critical in the management of patients with the condition, and imaging plays a central role in this process. Radiologists play a vital role in the multidisciplinary management of patients with peritoneal carcinosis. They need to have a thorough understanding of the pathophysiology of the condition, the underlying neoplasms, and the typical imaging findings. In addition, they need to be aware of the differential diagnoses and the advantages and disadvantages of the various imaging methods available. Imaging plays a central role in the diagnosis and quantification of lesions, and radiologists play a critical role in this process. Ultrasound, computed tomography, magnetic resonance, and PET/CT scans are used to diagnose peritoneal carcinosis. Each imaging procedure has advantages and disadvantages, and particular imaging techniques are recommended based on patient conditions. Our aim is to provide knowledge to radiologists regarding appropriate techniques, imaging findings, differential diagnoses, and treatment options. With the advent of AI in oncology, the future of precision medicine appears promising, and the interconnection between structured reporting and AI is likely to improve diagnostic accuracy and treatment outcomes for patients with peritoneal carcinosis.
    Keywords peritoneal carcinosis ; peritoneal cancer index ; computed tomography ; ultrasound ; magnetic resonance imaging ; radiomic features ; Medicine (General) ; R5-920
    Subject code 610
    Language English
    Publishing date 2023-06-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  2. Article ; Online: Universal Access to Advanced Imaging and Healthcare Protection

    Pietro Cappabianca / Gaetano Maria Russo / Umberto Atripaldi / Luigi Gallo / Maria Paola Rocco / Giovanni Pasceri / Michele A. A. Karaboue / Silvia Angioi / Salvatore Cappabianca / Alfonso Reginelli

    Medical Sciences, Vol 9, Iss 61, p

    UHC and Diagnostic Imaging

    2021  Volume 61

    Abstract: Universal Health Coverage (UHC) is a set of principles adopted by the World Health Organization (WHO) aimed to guarantee access to primary care for the entire world population through a range of essential health services without neglecting the diagnostic ...

    Abstract Universal Health Coverage (UHC) is a set of principles adopted by the World Health Organization (WHO) aimed to guarantee access to primary care for the entire world population through a range of essential health services without neglecting the diagnostic aspect. Italy is one of the signatory states, which means that diagnostic services should be appropriated and exigible throughout the national territory equally. Our research analyzed and identified the main criticalities in terms of age, territorial distribution, and technological and health appropriateness of installed Computed Tomography (CT) needed to meet the principles of UHC. Data analyzed in our study were published by Assobiomedica at the end of 2016 and by COCIR, which included and investigated the installed fleet of diagnostic equipment in the Italian sanitary system and in various European countries. The 6th point of the Alma Ata Declaration defines the concept of “primary health care”, which includes the importance of the diagnostic phase in the Italian health care system to provide Essential Levels of Assistance (LEA). It is clear from our studies that the technology at the national level is not adequate to satisfy the UHC principles or the European criteria, with negative effects on the diagnostic standards and on advanced screenings. This study conducted on the installed CTs in Italy at the end of 2016 confirms the persistence of progressive aging that has been recorded for several years in the health facilities of the country and suggests incentive policies for the replacement of obsolete equipment, which represent a form of investment rather than a cost, due to the nature of the expenditure itself, one-off and amortizable over time.
    Keywords diagnostic imaging ; installed CT fleet ; radiology ; UHC ; Medicine ; R
    Language English
    Publishing date 2021-09-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article ; Online: Coronavirus Disease 2019 (COVID-19) in Italy

    Alfonso Reginelli / Roberta Grassi / Beatrice Feragalli / Maria Paola Belfiore / Alessandro Montanelli / Gianluigi Patelli / Michelearcangelo La Porta / Fabrizio Urraro / Roberta Fusco / Vincenza Granata / Antonella Petrillo / Giuliana Giacobbe / Gaetano Maria Russo / Palmino Sacco / Roberto Grassi / Salvatore Cappabianca

    Biology, Vol 10, Iss 2, p

    Double Reading of Chest CT Examination

    2021  Volume 89

    Abstract: To assess the performance of the second reading of chest compute tomography (CT) examinations by expert radiologists in patients with discordance between the reverse transcription real-time fluorescence polymerase chain reaction (RT-PCR) test for COVID- ... ...

    Abstract To assess the performance of the second reading of chest compute tomography (CT) examinations by expert radiologists in patients with discordance between the reverse transcription real-time fluorescence polymerase chain reaction (RT-PCR) test for COVID-19 viral pneumonia and the CT report. Three hundred and seventy-eight patients were included in this retrospective study (121 women and 257 men; 71 years median age, with a range of 29–93 years) and subjected to RT-PCR tests for suspicious COVID-19 infection. All patients were subjected to CT examination in order to evaluate the pulmonary disease involvement by COVID-19. CT images were reviewed first by two radiologists who identified COVID-19 typical CT patterns and then reanalyzed by another two radiologists using a CT structured report for COVID-19 diagnosis. Weighted k values were used to evaluate the inter-reader agreement. The median temporal window between RT-PCRs execution and CT scan was zero days with a range of (−9, 11) days. The RT-PCR test was positive in 328/378 (86.8%). Discordance between RT-PCR and CT findings for viral pneumonia was revealed in 60 cases. The second reading changed the CT diagnosis in 16/60 (26.7%) cases contributing to an increase the concordance with the RT-PCR. Among these 60 cases, eight were false negative with positive RT-PCR, and 36 were false positive with negative RT-PCR. Sensitivity, specificity, positive predictive value and negative predictive value of CT were respectively of 97.3%, 53.8%, 89.0%, and 88.4%. Double reading of CT scans and expert second readers could increase the diagnostic confidence of radiological interpretation in COVID-19 patients.
    Keywords COVID-19 ; chest CT ; structured report ; double reading ; radiological signs ; Biology (General) ; QH301-705.5
    Subject code 610
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  4. Article ; Online: Secondary Complications in COVID-19 Patients

    Maria Paola Belfiore / Gaetano Maria Russo / Luigi Gallo / Umberto Atripaldi / Stefania Tamburrini / Valentina Caliendo / Luigi Impieri / Maria Teresa Del Canto / Giovanni Ciani / Pasquale Parrella / Maria Luisa Mangoni di Santo Stefano / Antonio Alessandro Heliot Salvia / Fabrizio Urraro / Valerio Nardone / Nicola Coppola / Alfonso Reginelli / Salvatore Cappabianca

    Tomography, Vol 8, Iss 154, Pp 1836-

    A Case Series

    2022  Volume 1850

    Abstract: Introduction. Coronavirus SARS-CoV-2, the causative agent of COVID-19, primarily causes a respiratory tract infection that is not limited to respiratory distress syndrome, but it is also implicated in other body systems. Systemic complications were ... ...

    Abstract Introduction. Coronavirus SARS-CoV-2, the causative agent of COVID-19, primarily causes a respiratory tract infection that is not limited to respiratory distress syndrome, but it is also implicated in other body systems. Systemic complications were reported due to an exaggerated inflammatory response, which involves severe alveolar damage in the lungs and exacerbates the hypercoagulation that leads to venous thrombosis, ischemic attack, vascular dysfunction and infarction of visceral abdominal organs. Some complications are related to anticoagulant drugs that are administrated to stabilize hypercoagulability, but increase the risk of bleeding, hematoma and hemorrhage. The aim of this study is to report the diagnostic role of CT in the early diagnosis and management of patients with severe COVID-19 complications through the most interesting cases in our experience. Material and Methods. The retrospective analysis of patients studied for COVID-19 in our institution and hospitals, which are part of the university training network, was performed. Cases. Pneumomediastinum, cortical kidney necrosis, splenic infarction, cerebral ischemic stroke, thrombosis of the lower limb and hematomas are the most major complications that are reviewed in this study. Conclusions. Since the onset of the COVID-19 pandemic, the CT imaging modality with its high sensitivity and specificity remains the preferred imaging choice to diagnose early the different complications associated with COVID-19, such as thrombosis, ischemic stroke, infarction and pneumomediastinum, and their management, which significantly improved the outcomes.
    Keywords COVID-19 ; complications ; SARS-CoV-2 ; Computer applications to medicine. Medical informatics ; R858-859.7
    Subject code 610 ; 616
    Language English
    Publishing date 2022-07-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  5. Article ; Online: Role of Cardiac Biomarkers in Non-Small Cell Lung Cancer Patients

    Valerio Nardone / Alfonso Reginelli / Giuseppina De Marco / Giovanni Natale / Vittorio Patanè / Marco De Chiara / Mauro Buono / Gaetano Maria Russo / Riccardo Monti / Giovanni Balestrucci / Maria Salvarezza / Gaetano Di Guida / Emma D’Ippolito / Angelo Sangiovanni / Roberta Grassi / Ida D’Onofrio / Maria Paola Belfiore / Giovanni Cimmino / Carminia Maria Della Corte /
    Giovanni Vicidomini / Alfonso Fiorelli / Antonio Gambardella / Floriana Morgillo / Salvatore Cappabianca

    Diagnostics, Vol 13, Iss 400, p

    2023  Volume 400

    Abstract: Treatment-induced cardiac toxicity represents an important issue in non-small cell lung cancer (NSCLC) patients, and no biomarkers are currently available in clinical practice. A novel and easy-to-calculate marker is the quantitative analysis of calcium ... ...

    Abstract Treatment-induced cardiac toxicity represents an important issue in non-small cell lung cancer (NSCLC) patients, and no biomarkers are currently available in clinical practice. A novel and easy-to-calculate marker is the quantitative analysis of calcium plaque in the coronary, calculated on CT. It is called the Agatston score (or CAD score). At the same time, other potential predictors include cardiac ultrasonography and anamnesis of the patients. Our work aimed to correlate cardiac biomarkers with overall survival (OS) in NSCLC patients. We retrospectively analyzed patients with NSCLC discussed in the Multidisciplinary Tumor Board of our Institute for the present analysis between January 2018 and July 2022. Inclusion criteria were the availability of basal CT imaging of the thorax, cardiac ultrasonography with the calculation of ejection fraction (EF), and complete anamnesis, including assessment of co-pathologies and pharmacological drugs. The clinical data of the patients were retrospectively collected, and the CAD scores was calculated on a CT scan. All of these parameters were correlated with overall survival (OS) with univariate analysis (Kaplan–Meier analysis) and multivariate analysis (Cox regression analysis). Following the above-mentioned inclusion criteria, 173 patients were included in the present analysis. Of those, 120 patients died in the follow-up period (69.6%), and the median overall survival (OS) was 28 months (mean 47.2 months, 95% CI, 36–57 months). In univariate analysis, several parameters that significantly correlated with lower OS were the stage ( p < 0.001), the CAD grading ( p < 0.001), history of ischemic heart disease ( p : 0.034), use of beta blocker drugs ( p : 0.036), and cardiac ejection fraction ( p : 0.005). In multivariate analysis, the only parameters that remained significant were as follows: CAD score ( p : 0.014, OR 1.56, 95% CI: 1.04–1.83), stage ( p : 0.016, OR: 1.26, 95% CI: 1.05–1.53), and cardiac ejection fraction ( p : 0.011, OR 0.46, 95% CI: 0.25–0.84). Both ...
    Keywords heart ; NSCLC ; biomarkers ; cardio-oncology ; radiotherapy ; Medicine (General) ; R5-920
    Subject code 610
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  6. Article ; Online: Chest CT Computerized Aided Quantification of PNEUMONIA Lesions in COVID-19 Infection

    Roberto Grassi / Salvatore Cappabianca / Fabrizio Urraro / Beatrice Feragalli / Alessandro Montanelli / Gianluigi Patelli / Vincenza Granata / Giuliana Giacobbe / Gaetano Maria Russo / Assunta Grillo / Angela De Lisio / Cesare Paura / Alfredo Clemente / Giuliano Gagliardi / Simona Magliocchetti / Diletta Cozzi / Roberta Fusco / Maria Paola Belfiore / Roberta Grassi /
    Vittorio Miele

    International Journal of Environmental Research and Public Health, Vol 17, Iss 6914, p

    A Comparison among Three Commercial Software

    2020  Volume 6914

    Abstract: Purpose: To compare different commercial software in the quantification of Pneumonia Lesions in COVID-19 infection and to stratify the patients based on the disease severity using on chest computed tomography (CT) images. Materials and methods: We ... ...

    Abstract Purpose: To compare different commercial software in the quantification of Pneumonia Lesions in COVID-19 infection and to stratify the patients based on the disease severity using on chest computed tomography (CT) images. Materials and methods: We retrospectively examined 162 patients with confirmed COVID-19 infection by reverse transcriptase-polymerase chain reaction (RT-PCR) test. All cases were evaluated separately by radiologists (visually) and by using three computer software programs: (1) Thoracic VCAR software, GE Healthcare, United States; (2) Myrian, Intrasense, France; (3) InferRead, InferVision Europe, Wiesbaden, Germany. The degree of lesions was visually scored by the radiologist using a score on 5 levels (none, mild, moderate, severe, and critic). The parameters obtained using the computer tools included healthy residual lung parenchyma, ground-glass opacity area, and consolidation volume. Intraclass coefficient (ICC), Spearman correlation analysis, and non-parametric tests were performed. Results: Thoracic VCAR software was not able to perform volumes segmentation in 26/162 (16.0%) cases, Myrian software in 12/162 (7.4%) patients while InferRead software in 61/162 (37.7%) patients. A great variability (ICC ranged for 0.17 to 0.51) was detected among the quantitative measurements of the residual healthy lung parenchyma volume, GGO, and consolidations volumes calculated by different computer tools. The overall radiological severity score was moderately correlated with the residual healthy lung parenchyma volume obtained by ThoracicVCAR or Myrian software, with the GGO area obtained by the ThoracicVCAR tool and with consolidation volume obtained by Myrian software. Quantified volumes by InferRead software had a low correlation with the overall radiological severity score. Conclusions: Computer-aided pneumonia quantification could be an easy and feasible way to stratify COVID-19 cases according to severity; however, a great variability among quantitative measurements provided by computer tools should ...
    Keywords COVID-19 ; computed tomography ; computer-aided quantification ; Medicine ; R
    Subject code 303
    Language English
    Publishing date 2020-09-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top