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  1. Article: Five Things to Know About Restless Legs Syndrome in Patients on Dialysis.

    Prasad, Bhanu / Gagarinova, Maria / Sharma, Aditi

    Canadian journal of kidney health and disease

    2023  Volume 10, Page(s) 20543581231164275

    Language English
    Publishing date 2023-03-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 2765462-X
    ISSN 2054-3581
    ISSN 2054-3581
    DOI 10.1177/20543581231164275
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Five Things to Know About Pruritus in Patients on Dialysis.

    Prasad, Bhanu / Gagarinova, Maria / Sharma, Aditi

    Canadian journal of kidney health and disease

    2023  Volume 10, Page(s) 20543581221149620

    Language English
    Publishing date 2023-01-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 2765462-X
    ISSN 2054-3581
    ISSN 2054-3581
    DOI 10.1177/20543581221149620
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis.

    Moutaoufik, Mohamed Taha / Malty, Ramy / Amin, Shahreen / Zhang, Qingzhou / Phanse, Sadhna / Gagarinova, Alla / Zilocchi, Mara / Hoell, Larissa / Minic, Zoran / Gagarinova, Maria / Aoki, Hiroyuki / Stockwell, Jocelyn / Jessulat, Matthew / Goebels, Florian / Broderick, Kirsten / Scott, Nichollas E / Vlasblom, James / Musso, Gabriel / Prasad, Bhanu /
    Lamantea, Eleonora / Garavaglia, Barbara / Rajput, Alex / Murayama, Kei / Okazaki, Yasushi / Foster, Leonard J / Bader, Gary D / Cayabyab, Francisco S / Babu, Mohan

    iScience

    2019  Volume 19, Page(s) 1114–1132

    Abstract: Mitochondrial protein (MP) assemblies undergo alterations during neurogenesis, a complex process vital in brain homeostasis and disease. Yet which MP assemblies remodel during differentiation remains unclear. Here, using mass spectrometry-based co- ... ...

    Abstract Mitochondrial protein (MP) assemblies undergo alterations during neurogenesis, a complex process vital in brain homeostasis and disease. Yet which MP assemblies remodel during differentiation remains unclear. Here, using mass spectrometry-based co-fractionation profiles and phosphoproteomics, we generated mitochondrial interaction maps of human pluripotent embryonal carcinoma stem cells and differentiated neuronal-like cells, which presented as two discrete cell populations by single-cell RNA sequencing. The resulting networks, encompassing 6,442 high-quality associations among 600 MPs, revealed widespread changes in mitochondrial interactions and site-specific phosphorylation during neuronal differentiation. By leveraging the networks, we show the orphan C20orf24 as a respirasome assembly factor whose disruption markedly reduces respiratory chain activity in patients deficient in complex IV. We also find that a heme-containing neurotrophic factor, neuron-derived neurotrophic factor [NENF], couples with Parkinson disease-related proteins to promote neurotrophic activity. Our results provide insights into the dynamic reorganization of mitochondrial networks during neuronal differentiation and highlights mechanisms for MPs in respirasome, neuronal function, and mitochondrial diseases.
    Language English
    Publishing date 2019-09-04
    Publishing country United States
    Document type Journal Article
    ISSN 2589-0042
    ISSN (online) 2589-0042
    DOI 10.1016/j.isci.2019.08.057
    Database MEDical Literature Analysis and Retrieval System OnLINE

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