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  1. Article ; Online: Improving Tolerance to Snorkel Mask Use as Alternative Personal Protective Equipment.

    Aljafar, Ghassan / Connelly, Neil Roy / Gagnon, Greg / Aljafar, Hassan

    A&A practice

    2021  Volume 15, Issue 4, Page(s) e01449

    Abstract: Snorkel masks have become an option for personal protective equipment (PPE) due to the shortage of air filtration at least 95% of airborne particle (N95) masks as a result of the coronavirus disease 2019 (COVID-19) pandemic. We developed a 3D design of a ...

    Abstract Snorkel masks have become an option for personal protective equipment (PPE) due to the shortage of air filtration at least 95% of airborne particle (N95) masks as a result of the coronavirus disease 2019 (COVID-19) pandemic. We developed a 3D design of a triheaded adapter that connects a snorkel mask to 3 different National Institute for Occupational Safety and Health (NIOSH)-approved air filtration at least 99% of airborne particles (N99) filters with the aim of improving wearer comfort. We measured the resistance of the new triheaded adapter to be one-third the resistance of the single adapter. Interdepartmental survey of anesthesiologists showed an improvement in perceived comfort when using the triheaded adapter as compared to the single adapter.
    MeSH term(s) Anesthesiologists/standards ; Anesthesiologists/trends ; COVID-19/epidemiology ; COVID-19/prevention & control ; Equipment Design/standards ; Equipment Design/trends ; Humans ; Masks/standards ; Masks/trends ; Occupational Exposure/prevention & control ; Personal Protective Equipment/standards ; Personal Protective Equipment/trends
    Language English
    Publishing date 2021-04-27
    Publishing country United States
    Document type Journal Article
    ISSN 2575-3126
    ISSN (online) 2575-3126
    DOI 10.1213/XAA.0000000000001449
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Validation of a simple technique of volumetric analysis of complex incisional hernias without 3D CT scan reconstruction.

    Al-Mansour, Mazen R / Wu, Jacqueline / Gagnon, Greg / Knee, Alexander / Romanelli, John / Seymour, Neal E

    Surgical endoscopy

    2021  Volume 36, Issue 3, Page(s) 1936–1942

    Abstract: Purpose: Volumetric analysis is being increasingly utilized in the preoperative evaluation of complex incisional hernias. Three-dimensional (3D) reconstruction of abdominal computed tomography (CT) scan has been used to obtain surface area (SA) and ... ...

    Abstract Purpose: Volumetric analysis is being increasingly utilized in the preoperative evaluation of complex incisional hernias. Three-dimensional (3D) reconstruction of abdominal computed tomography (CT) scan has been used to obtain surface area (SA) and volume (Vol.) measurements, while others have used simple mathematical formulas to obtain SA and Vol. estimates without 3D reconstruction. Our objective was to assess the correlation of SA and Vol. measurements and estimates of complex incisional hernias.
    Methods: We conducted a retrospective agreement study of adults who underwent abdominal wall reconstruction from 2007 to 2018. Demographics, hernia characteristics, and operative data were collected from the medical record. SA and Vol. measurements were obtained after 3D CT reconstruction. Linear CT variables were obtained independently by two surgeons and SA and Vol. estimates were calculated. Because both surgeons reported similar results, only lead author values are reported in the abstract. We used Pearson's correlation coefficient (r) to assess inter-rater agreement and the agreement between SA and Vol. measurements and estimates.
    Results: A total of 108 patients were eligible for analysis. The mean age was 57 ± 11 years and 53 (49%) were female. 42 (39%) hernias were recurrent, 10 (9%) patients had a stoma, and 9 (8%) had a history of open abdomen. The mean defect width was 11 ± 4 cm and mean defect surface area (DSA) was 150 ± 95 cm
    Conclusion: SA and Vol. estimates demonstrated high level of agreement with SA and Vol. measurements using 3D reconstruction. SA and Vol. estimates can be obtained using simple mathematical formulas using easily obtained linear variables negating the need for the time and effort consuming 3D reconstruction.
    MeSH term(s) Abdomen/surgery ; Abdominal Cavity/surgery ; Adult ; Aged ; Female ; Hernia, Ventral/diagnostic imaging ; Hernia, Ventral/surgery ; Herniorrhaphy/methods ; Humans ; Incisional Hernia/diagnostic imaging ; Incisional Hernia/surgery ; Middle Aged ; Retrospective Studies ; Surgical Mesh ; Tomography, X-Ray Computed/methods
    Language English
    Publishing date 2021-04-15
    Publishing country Germany
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 639039-0
    ISSN 1432-2218 ; 0930-2794
    ISSN (online) 1432-2218
    ISSN 0930-2794
    DOI 10.1007/s00464-021-08476-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2214: Show issues Location:
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  3. Article ; Online: Aerosol Delivery Through Adult High Flow Nasal Cannula With Heliox and Oxygen.

    Dailey, Patricia A / Harwood, Robert / Walsh, Kyle / Fink, James B / Thayer, Tina / Gagnon, Greg / Ari, Arzu

    Respiratory care

    2017  Volume 62, Issue 9, Page(s) 1186–1192

    Abstract: Background: Heliox (helium-oxygen mixture) has been shown to reduce turbulence and improve aerosol delivery in a range of clinical settings. We questioned whether heliox as compared with oxygen via high-flow nasal cannula (HFNC) would affect aerosol ... ...

    Abstract Background: Heliox (helium-oxygen mixture) has been shown to reduce turbulence and improve aerosol delivery in a range of clinical settings. We questioned whether heliox as compared with oxygen via high-flow nasal cannula (HFNC) would affect aerosol delivery. We hypothesized that heliox would have a significant effect on aerosol delivery as compared with oxygen with both quiet and distressed breathing patterns.
    Methods: A vibrating mesh nebulizer was placed at the inlet of a humidifier via HFNC with small adult cannula distal to the heated-wire circuit with prongs placed into simulated nares with a T-shaped trap and absolute filter connected to a breath simulator set to adult quiet and distressed breathing parameters. Albuterol sulfate (0.083% 2.5 mg/3 mL) was aerosolized with heliox (80:20) and oxygen (100%) at 10, 30, and 50 L/min. Drug eluted from the filter was assayed with UV spectrophotometry (276 nm). Descriptive statistics, Kruskal-Wallis test, and Mann-Whitney U test were used for data analysis.
    Results: Increasing flows with heliox and oxygen significantly decreased percentage inhaled dose (inhaled dose) of aerosol with a quiet breathing pattern (
    Conclusions: With a distressed breathing pattern, aerosol delivery was greater at 30 and 50 L/min than with a quiet breathing pattern. Trends toward higher inhaled dose with heliox during HFNC were not significant.
    Language English
    Publishing date 2017-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603252-7
    ISSN 1943-3654 ; 0098-9142 ; 0020-1324
    ISSN (online) 1943-3654
    ISSN 0098-9142 ; 0020-1324
    DOI 10.4187/respcare.05127
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2285: Show issues Location:
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  4. Article ; Online: Stereotactic body radiation therapy for reirradiation of localized adenocarcinoma of the pancreas

    Lominska Chris E / Unger Keith / Nasr Nadim M / Haddad Nadim / Gagnon Greg

    Radiation Oncology, Vol 7, Iss 1, p

    2012  Volume 74

    Abstract: Abstract Background Local control rates are poor in the treatment of pancreatic cancer. We investigated the role of hypofractionated stereotactic body radiation therapy (SBRT) for salvage or boost treatment after conventional doses of external beam ... ...

    Abstract Abstract Background Local control rates are poor in the treatment of pancreatic cancer. We investigated the role of hypofractionated stereotactic body radiation therapy (SBRT) for salvage or boost treatment after conventional doses of external beam radiation therapy. Methods All patients treated with SBRT for pancreatic adenocarcinoma at Georgetown University from June 2002 through July 2007 were examined. Eligible patients had prior external beam radiation therapy to the pancreas. Treatment parameters and clinical and radiographic follow-up were evaluated. Results Twenty-eight patients were identified who received SBRT after a median prior external beam radiotherapy dose of 50.4 Gy. The median patient age was 63 years old and the median follow-up was 5.9 months. Twelve of fourteen (85.7%) evaluable patients were free from local progression, with three partial responses and nine patients with stable disease. Toxicity consisted of one case of acute Grade II nausea/vomiting, and two cases of Grade III late GI toxicity. The median overall survival was 5.9 months, with 18% survival and 70% freedom from local progression at one year. Conclusions Hypofractionated SBRT reirradiation of localized pancreatic cancer is a well-tolerated treatment. Most patients are free from local progression, albeit with limited follow-up, but overall survival remains poor.
    Keywords SBRT ; Reirradiation ; Radiotherapy ; Pancreatic cancer ; Medical physics. Medical radiology. Nuclear medicine ; R895-920 ; Neoplasms. Tumors. Oncology. Including cancer and carcinogens ; RC254-282
    Subject code 610 ; 616
    Language English
    Publishing date 2012-05-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Stereotactic body radiation therapy for reirradiation of localized adenocarcinoma of the pancreas.

    Lominska, Chris E / Unger, Keith / Nasr, Nadim M / Haddad, Nadim / Gagnon, Greg

    Radiation oncology (London, England)

    2012  Volume 7, Page(s) 74

    Abstract: Background: Local control rates are poor in the treatment of pancreatic cancer. We investigated the role of hypofractionated stereotactic body radiation therapy (SBRT) for salvage or boost treatment after conventional doses of external beam radiation ... ...

    Abstract Background: Local control rates are poor in the treatment of pancreatic cancer. We investigated the role of hypofractionated stereotactic body radiation therapy (SBRT) for salvage or boost treatment after conventional doses of external beam radiation therapy.
    Methods: All patients treated with SBRT for pancreatic adenocarcinoma at Georgetown University from June 2002 through July 2007 were examined. Eligible patients had prior external beam radiation therapy to the pancreas. Treatment parameters and clinical and radiographic follow-up were evaluated.
    Results: Twenty-eight patients were identified who received SBRT after a median prior external beam radiotherapy dose of 50.4 Gy. The median patient age was 63 years old and the median follow-up was 5.9 months. Twelve of fourteen (85.7%) evaluable patients were free from local progression, with three partial responses and nine patients with stable disease. Toxicity consisted of one case of acute Grade II nausea/vomiting, and two cases of Grade III late GI toxicity. The median overall survival was 5.9 months, with 18% survival and 70% freedom from local progression at one year.
    Conclusions: Hypofractionated SBRT reirradiation of localized pancreatic cancer is a well-tolerated treatment. Most patients are free from local progression, albeit with limited follow-up, but overall survival remains poor.
    MeSH term(s) Adenocarcinoma/mortality ; Adenocarcinoma/radiotherapy ; Adenocarcinoma/surgery ; Adult ; Aged ; Aged, 80 and over ; Dose Fractionation, Radiation ; Female ; Humans ; Male ; Middle Aged ; Pancreatic Neoplasms/mortality ; Pancreatic Neoplasms/radiotherapy ; Pancreatic Neoplasms/surgery ; Radiation Dosage ; Radiosurgery/methods ; Radiotherapy, Adjuvant ; Retrospective Studies ; Survival Analysis
    Language English
    Publishing date 2012-05-18
    Publishing country England
    Document type Evaluation Study ; Journal Article
    ZDB-ID 2224965-5
    ISSN 1748-717X ; 1748-717X
    ISSN (online) 1748-717X
    ISSN 1748-717X
    DOI 10.1186/1748-717X-7-74
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Pathologic quiz case: a 15-year-old adolescent boy with a groin mass present for 18 months.

    Wetzler, Samantha Berlin / Gagnon, Greg A / Williams, H James

    Archives of pathology & laboratory medicine

    2003  Volume 127, Issue 5, Page(s) e251–2

    MeSH term(s) Adolescent ; Groin/pathology ; Groin/surgery ; Histiocytosis, Sinus/diagnosis ; Histiocytosis, Sinus/surgery ; Humans ; Male
    Language English
    Publishing date 2003-05
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 194119-7
    ISSN 1543-2165 ; 0363-0153 ; 0096-8528 ; 0003-9985
    ISSN (online) 1543-2165
    ISSN 0363-0153 ; 0096-8528 ; 0003-9985
    DOI 10.5858/2003-127-e251-PQCAYO
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ud II Zs.36: Show issues Location:
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