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Article ; Online: Stage IV endometriosis: to treat or not to treat before in-vitro fertilization? Further considerations besides the pregnancy rate: a case of near-miss for spontaneous hemoperitoneum.

Gaia, Giorgia / Afonina, Margarita / Marconi, Anna M

2022 Volume 74, Issue 3, Page(s) 314–317

Abstract: Endometriosis represents a well-known cause of infertility. Recently, its association with spontaneous hemoperitoneum in pregnancy (SHIP) was reported. Its occurrence seems to be increased in patients with endometriosis who underwent IVF techniques. We ... ...

Abstract	Endometriosis represents a well-known cause of infertility. Recently, its association with spontaneous hemoperitoneum in pregnancy (SHIP) was reported. Its occurrence seems to be increased in patients with endometriosis who underwent IVF techniques. We present a case of near miss at 15 weeks of pregnancy associated with SHIP in a nulliparous patient of 39 years old with chronic endometriosis. Previously, she underwent several IVF cycles and controlled ovarian hyperstimulation plus embryo transfer (COH-ET). An explorative laparoscopy was performed, then converted in laparotomy. The bleeding endometriotic tissue was removed and an ureteral stent was placed. The patient lost a total of 4 liters of blood and fully recovered. Unfortunately, miscarriage occurred. The potential link between COH-ET, the number of cycles of ovarian stimulation and SHIP in severe endometriosis must take a part in the balanced decision between preventive surgery of direct hormonal stimulation.
MeSH term(s)	Adult ; Endometriosis/complications ; Endometriosis/pathology ; Endometriosis/therapy ; Female ; Fertilization in Vitro/adverse effects ; Hemoperitoneum/etiology ; Humans ; Near Miss, Healthcare ; Pregnancy ; Pregnancy Rate
Language	English
Publishing date	2022-06-01
Publishing country	Italy
Document type	Case Reports
ZDB-ID	3062815-5
ISSN	2724-6450
ISSN (online)	2724-6450
DOI	10.23736/S2724-606X.22.05038-2
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Article ; Online: Robotic multiple sigmoid and rectal mucosa skinning in a multicentric deep infiltrating bowel endometriotic nodules: a case report.

Gaia, Giorgia / Afonina, Margarita / Sighinolfi, Maria Chiara / Formisano, Giampaolo / Bianchi, Paolo Pietro / Marconi, Anna Maria

Journal of minimally invasive surgery

2023 Volume 26, Issue 3, Page(s) 146–150

Abstract: Endometriosis is a benign gynecological disease characterized by the presence of endometrial tissue outside the uterus. The eradication of non-gynecological localizations represents the real surgical challenge. A 29-year-old woman underwent robotic ... ...

Abstract	Endometriosis is a benign gynecological disease characterized by the presence of endometrial tissue outside the uterus. The eradication of non-gynecological localizations represents the real surgical challenge. A 29-year-old woman underwent robotic surgery with the Da Vinci system (Intuitive Surgical Inc.) for a diagnosis of stage IV deep endometriosis. The patient presented with 5 cm left ovarian endometrioma, an infiltration of the left posterior parametrium, and bilateral ureteral endometriosis. Once inside the pelvic cavity, deep intestinal infiltrating endometriosis implants were confirmed as triple, multicentric, and multifocal lesions, affected distal sigmoid, rectosigmoid junction, and upper rectum. An expert multiple excision, sparing the intestinal mucosa, was performed. To our knowledge, this is the first description of a multiple robotic shaving of multicentric endometriotic intestinal lesions. After the surgery, a normal diet was quickly restored, accelerating the recovery of the physiological peristalsis and the overall recovery time.
Language	English
Publishing date	2023-09-15
Publishing country	Korea (South)
Document type	Case Reports
ISSN	2234-5248
ISSN (online)	2234-5248
DOI	10.7602/jmis.2023.26.3.146
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Article ; Online: T-shaped uterus: what has been done, what should be done.

La Marca, Antonio / Imbrogno, Maria G / Gaia, Giorgia / Alboni, Carlo

Minerva obstetrics and gynecology

2021 Volume 73, Issue 4, Page(s) 500–505

Abstract: T-shaped uterus is a uterine malformation which has been suggested to be associated with poor reproductive performance. Over the years, different diagnostic methods have been used to determine the anatomical status of the female genital tract and to ... ...

Abstract	T-shaped uterus is a uterine malformation which has been suggested to be associated with poor reproductive performance. Over the years, different diagnostic methods have been used to determine the anatomical status of the female genital tract and to recognize any anomalies and the 3D-ultrasound is now considered the gold standard in diagnosing uterine anomalies. The importance of a correct diagnosis of the T-shaped uterus relates to the impact that such malformation has on female fertility. Although, to date, the prevalence does not seem to be so high, the fertility of the woman is reported to be somehow compromised by this uterine dysmorphism. Correcting the abnormal uterine morphology could be the main goal in order to optimize reproductive outcomes. To date, hysteroscopic correction of T-shaped uterus may be considered in patients with infertility, recurrent miscarriages or recurrent IVF failure. However, the absence of randomized controlled trials, multicentric data and the difficulty to state that metroplasty was the reason for improved outcome, make the data available inconclusive. More studies, led by an objective diagnosis, are urgently needed to understand the real impact of T-shaped uterus on the reproductive life of women and its effective prevalence in the population of infertile women.
MeSH term(s)	Female ; Humans ; Hysteroscopy ; Infertility, Female ; Pregnancy ; Urogenital Abnormalities/diagnosis ; Uterus/abnormalities ; Uterus/diagnostic imaging
Language	English
Publishing date	2021-08-03
Publishing country	Italy
Document type	Journal Article
ZDB-ID	3062815-5
ISSN	2724-6450
ISSN (online)	2724-6450
DOI	10.23736/S2724-606X.21.04825-9
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Article ; Online: Reproducibility of a modified posterior reconstruction during robotic intracorporeal neobladder reconfiguration.

Rocco, Bernardo / Assumma, Simone / Calcagnile, Tommaso / Sangalli, Mattia / Turri, Filippo / Micali, Salvatore / Gaia, Giorgia / Bozzini, Giorgio / Sighinolfi, Maria Chiara

International braz j urol : official journal of the Brazilian Society of Urology

2023 Volume 49, Issue 1, Page(s) 136–142

Abstract: Objective: Robotic intracorporeal neobladder reconstruction is a complex procedure in which the approximation of the reservoir to the urethral stump can be a demanding step. The aim of the study is to evaluate the reproducibility of a modified posterior ...

Abstract	Objective: Robotic intracorporeal neobladder reconstruction is a complex procedure in which the approximation of the reservoir to the urethral stump can be a demanding step. The aim of the study is to evaluate the reproducibility of a modified posterior reconstruction (PR) during the reconfiguration of intracorporeal neobladder after robot assisted radical cystectomy (RARC). Materials and methods: From July 2021 to July 2022, 35 RARC were performed, and 17 patients underwent intracorporeal neobladder reconstruction. A PR was planned in males (14). Intra- and peri-operative data were collected. Surgical technique: RARC and node dissection are performed. Afterwards, 40-cm ileal segment is isolated; the portion with the more adequate mesenteric length is brought down to the pelvis. A modified PR is performed with a double-armed barbed suture: a first layer connects the Denonvillier's fascia to the rhabdosphincter in a running fashion; the second layer is created with the other arm and approximates the posterior side of the ileal segment towards the urethral stump. In the anterior caudal part of the ileum, a 1.5-cm incision is made to realize the neobladder neck; the neovesical-urethral anastomosis is performed with a second bidirectional suture. Results: Anastomotic and PR time were 14 (range 7-20) and 5 minutes (4-8), respectively. A single Clavien IIIa complication was recorded in a patient who underwent NAC and had a C. albicans superinfection in the post-operative course. All patients were discharged with complete or acceptable bladder voiding. Twelve patients with follow-up >90-days reported a satisfying daytime continence. Conclusions: PR represents a simple technical refinement that improves neobladder-urethral anastomosis by favoring ileal approximation to the urethral stump and decreasing anastomotic tension.
MeSH term(s)	Male ; Humans ; Robotics ; Robotic Surgical Procedures/methods ; Reproducibility of Results ; Urinary Bladder Neoplasms/surgery ; Cystectomy/methods ; Treatment Outcome ; Urinary Diversion/methods
Language	English
Publishing date	2023-02-01
Publishing country	Brazil
Document type	Journal Article ; Comment
ZDB-ID	2206649-4
ISSN	1677-6119 ; 1677-5538
ISSN (online)	1677-6119
ISSN	1677-5538
DOI	10.1590/S1677-5538.IBJU.2022.0417
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Article ; Online: Perceived usefulness of the nurse-patient therapeutic relationship in the rehabilitation journey of people with urinary incontinence: A mixed-method study.

Terzoni, Stefano / Mora, Cristina / Vahr Lauridssen, Susanne / N'Guessan, Serge / Sighinolfi Maria, Chiara / Gaia, Giorgia / Rocco, Bernardo / Afonina, Margarita / Maruccia, Serena / Pinna, Barbara / Parozzi, Mauro / Ferrara, Paolo / Destrebecq, Anne / Marley, Jerome

Neurourology and urodynamics

2024 Volume 43, Issue 4, Page(s) 942–950

Abstract: Introduction: Despite various studies on the impact of incontinence on patients' lives, the existing literature has not investigated the contribution of nursing care during rehabilitation in terms of quality of life. Fewer data, therefore, exist on the ... ...

Abstract	Introduction: Despite various studies on the impact of incontinence on patients' lives, the existing literature has not investigated the contribution of nursing care during rehabilitation in terms of quality of life. Fewer data, therefore, exist on the characteristics and perceived impact of the therapeutic relationship as part of the rehabilitation program. Aims: To investigate the characteristics of the nurse-patient therapeutic relationship and its impact throughout the rehabilitation program; to describe the levels of patient burden on everyday activities. Materials and methods: A monocentric, retrospective, multimethod descriptive study was conducted in the nurse-led continence clinic of a major teaching hospital in Northern Italy. A phenomenological approach with semistructured interviews was adopted after 6 weeks of rehabilitation, following the method of phenomenological enquiry by Giorgi. The short form 12 questionnaire was administered upon admission of patients to the clinic, after 6 weeks, and during the last consultation to investigate the impact of urinary incontinence (UI) on daily activities and physical and psychological quality of life. Results: Ninety-one adult patients of both genders presenting for nonneurogenic nonpostpartum UI were consecutively enrolled. Physical scores (PCS-12) and MCS-12 scores significantly increased over time. Psychological scores showed great variability upon admission, which was reduced halfway through the rehabilitation program. The thematic analysis highlighted four categories based on data saturation: the impact of UI on daily activities, strategies to face the problem, feelings, and the role of nurses. Conclusions: This mixed-method investigation suggests the importance of therapeutic nursing relationships, clinical expertise, and rehabilitative skills. Quality of life is arguably related to the positive results of the rehabilitation program but also to the environment, patients perceive in terms of support, honesty, and trust.
MeSH term(s)	Adult ; Humans ; Male ; Female ; Quality of Life ; Retrospective Studies ; Urinary Incontinence/psychology ; Surveys and Questionnaires ; Hospitalization
Language	English
Publishing date	2024-02-26
Publishing country	United States
Document type	Journal Article
ZDB-ID	604904-7
ISSN	1520-6777 ; 0733-2467
ISSN (online)	1520-6777
ISSN	0733-2467
DOI	10.1002/nau.25432
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Article ; Online: Hysteroscopic findings in chronic endometritis.

La Marca, Antonio / Gaia, Giorgia / Mignini Renzini, Mario / Alboni, Carlo / Mastellari, Elisa

Minerva obstetrics and gynecology

2021 Volume 73, Issue 6, Page(s) 790–805

Abstract: Chronic endometritis (CE) is a subtle pathology. Despite being difficult to detect and probably underdiagnosed, it has great clinical relevance, representing as it does a reversible cause of infertility. Nowadays, histological examination with ... ...

Abstract	Chronic endometritis (CE) is a subtle pathology. Despite being difficult to detect and probably underdiagnosed, it has great clinical relevance, representing as it does a reversible cause of infertility. Nowadays, histological examination with identification of endometrial stromal plasma cells is considered the gold standard for diagnosis. Diagnostic difficulties persist, however, as a result of the technical limitations of this method and the lack of standardized histological diagnostic criteria. Hysteroscopy has been proposed as an aid for CE diagnosis. The method works by detecting signs of inflammation (focal or diffuse hyperemia, stromal edema, presence of micropolyps and the typical strawberry aspect) on the endometrial surface. Yet, the jury is still out on how reliable this technique is. Hysteroscopy displays a high sensitivity (over 86% and up to 100%) and high negative predictive value (over 92% and up to 100%) in the diagnosis of CE, and it should probably be performed routinely in the assessment of patients with unexplained infertility, repeated implantation failure and repeated pregnancy loss; however, since values in the literature regarding specificity are conflicting, in cases of suspected CE, hysteroscopy may be combined with histological examination, which remains the gold standard to confirm CE. Considering that histopathological evaluation probably underdiagnoses CE, and that hysteroscopy tends to overdiagnose, further studies are needed to determine which technique (or combination of techniques) has greater value for patients.
MeSH term(s)	Biopsy ; Endometritis/diagnosis ; Endometrium ; Female ; Humans ; Hysteroscopy ; Pregnancy ; Sensitivity and Specificity
Language	English
Publishing date	2021-12-09
Publishing country	Italy
Document type	Journal Article
ZDB-ID	3062815-5
ISSN	2724-6450
ISSN (online)	2724-6450
DOI	10.23736/S2724-606X.21.04970-8
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Article: A nurse-led educational intervention for relieving idiopathic constipation: a retrospective study.

Terzoni, Stefano / Mora, Cristina / Rocco, Bernardo / Sighinolfi, Chiara / Gaia, Giorgia / Ferrara, Paolo / Pinna, Barbara / Destrebecq, Anne

British journal of nursing (Mark Allen Publishing)

2022 Volume 31, Issue 19, Page(s) 984–988

Abstract: Background: Constipation is a common condition. Although numerous articles emphasise the importance of conservative interventions, none have set out a complete educational programme.: Aims: To describe the results of an evidence-based, nurse-led ... ...

Abstract	Background: Constipation is a common condition. Although numerous articles emphasise the importance of conservative interventions, none have set out a complete educational programme. Aims: To describe the results of an evidence-based, nurse-led educational intervention for functional constipation in adults. Methods: A retrospective study of patient records with an analysis of Wexner constipation scores and Bristol stool charts was carried out before and after a nurse-led educational programme on nutrition and bowel habits. Findings: Twenty-nine patients were enrolled (19 women and 10 men), with a median age of 61 (53-71) years, a mean BMI of 24.4±3.88 kg/m Conclusion: The results suggest this investigation should be repeated on a larger scale. An educational intervention could be included in all consultations on any issue that could affect bowel activity.
MeSH term(s)	Adult ; Male ; Humans ; Female ; Middle Aged ; Aged ; Retrospective Studies ; Nurse's Role ; Constipation/therapy
Language	English
Publishing date	2022-08-08
Publishing country	England
Document type	Journal Article
ZDB-ID	1119191-0
ISSN	0966-0461
ISSN	0966-0461
DOI	10.12968/bjon.2022.31.19.984
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Article ; Online: Pelvic lymph node dissection in prostate and bladder cancers: a narrative review.

Rocco, Bernardo / Eissa, Ahmed / Gaia, Giorgia / Assumma, Simone / Sarchi, Luca / Bozzini, Giorgio / Micali, Salvatore / Calcagnile, Tommaso / Sighinolfi, Maria C

Minerva urology and nephrology

2022

Abstract: Prostate cancer and bladder cancer accounts for approximately 13.5% and 3% of all male cancers and all newly diagnosed cancers (regardless sex), respectively. Thus, these cancers represent a major health and economic burden globally. The knowledge of ... ...

Abstract	Prostate cancer and bladder cancer accounts for approximately 13.5% and 3% of all male cancers and all newly diagnosed cancers (regardless sex), respectively. Thus, these cancers represent a major health and economic burden globally. The knowledge of lymph node status is an integral part of the management of any solid tumor. In the urological field, pelvic lymph node dissection (PLND) is of paramount importance in the diagnosis, management, and prognosis of prostate and bladder cancers. However, PLND may be associated with several comorbidities. In this narrative review, the most recent updates concerning the patterns and incidence of lymph node metastasis, the role of different imaging studies and nomograms in determining patients' eligibility for PLND, and the anatomical templates of PLND in urologic patients with bladder or prostate cancer will be discussed.
Language	English
Publishing date	2022-10-05
Publishing country	Italy
Document type	Journal Article
ZDB-ID	3062840-4
ISSN	2724-6442
ISSN (online)	2724-6442
DOI	10.23736/S2724-6051.22.04904-7
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Article ; Online: New robotic systems: first head-to-head comparison between Hugo RAS and Versius CMR in the pre-clinical setting.

Sighinolfi, Maria C / Rocco, Bernardo / Terzoni, Stefano / Morandi, Alessandro / Afonina, Margarita / Assumma, Simone / Calcagnile, Tommaso / Turri, Filippo / Sangalli, Mattia / Panio, Enrico / Sarchi, Luca / Grasso, Angelica / Dell'orto, Paolo / Pozzi, Efrem / Ramondo, Augusto / Santangelo, Emanuela / Petix, Michele / Gaia, Giorgia

Minerva urology and nephrology

2024 Volume 76, Issue 1, Page(s) 1–4

MeSH term(s)	Robotic Surgical Procedures
Language	English
Publishing date	2024-02-15
Publishing country	Italy
Document type	Editorial
ZDB-ID	3062840-4
ISSN	2724-6442
ISSN (online)	2724-6442
DOI	10.23736/S2724-6051.23.05568-4
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Article ; Online: Corrigendum to "Rectal Perforation During Pelvic Surgery" [Eur Urol Open Sci 44 (2022) 54-59].

Rocco, Bernardo / Gaia, Giorgia / Assumma, Simone / Calcagnile, Tommaso / Sangalli, Mattia / Terzoni, Stefano / Eissa, Ahmed / Bozzini, Giorgio / De Concilio, Bernardino / Celia, Antonio / Micali, Salvatore / Sighinolfi, Maria Chiara

European urology open science

2023 Volume 49, Page(s) 10

Abstract: This corrects the article DOI: 10.1016/j.euros.2022.04.006.]. ...

Abstract	[This corrects the article DOI: 10.1016/j.euros.2022.04.006.].
Language	English
Publishing date	2023-01-20
Publishing country	Netherlands
Document type	Published Erratum
ZDB-ID	3040546-4
ISSN	2666-1683 ; 2058-4881
ISSN (online)	2666-1683
ISSN	2058-4881
DOI	10.1016/j.euros.2023.01.001
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