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  1. Article: SARS-CoV-2, Uncontrolled Diabetes and Corticosteroids-An Unholy Trinity in Invasive Fungal Infections of the Maxillofacial Region? A Retrospective, Multi-centric Analysis.

    Moorthy, Aditya / Gaikwad, Rohith / Krishna, Shreya / Hegde, Raghuraj / Tripathi, K K / Kale, Preeti G / Rao, P Subramanya / Haldipur, Deepak / Bonanthaya, Krishnamurthy

    Journal of maxillofacial and oral surgery

    2021  Volume 20, Issue 3, Page(s) 418–425

    Abstract: Objectives: Collate and analyse data of maxillofacial/rhino-cerebro-orbital fungal infections reported during the era of the Covid-19 pandemic, with the aim of investigating the common contributing factors leading to such infections and of highlighting ... ...

    Abstract Objectives: Collate and analyse data of maxillofacial/rhino-cerebro-orbital fungal infections reported during the era of the Covid-19 pandemic, with the aim of investigating the common contributing factors leading to such infections and of highlighting the significance of this surge seen in patients infected with SARS-CoV-2.
    Method: This retrospective observational multi-centric study analysed patient data collected from clinicians belonging to different specialties in Bangalore, India. The data included the presentation and management of patients presenting with aggressive maxillofacial and rhino-cerebro-orbital fungal infections and explored the relationship between SARS-CoV-2, corticosteroid administration and uncontrolled diabetes mellitus.
    Results: All 18 patients were Covid positive. Sixteen of the 18 patients received steroids for Covid treatment and 16 patients were diabetic (of whom 15 patients who were diabetics received steroids for Covid-19 treatment). Loss of vision was noted in 12 of the 18 patients and 7 of them underwent orbital exenteration. The fungi noted was mucormycosis in 16 patients, aspergillosis in 1 patient and a mixed fungal infection in 1 patient. Eleven of the patients survived, 6 died and 1 was lost to follow-up. There was a significantly higher incidence of diabetes (
    Conclusion: Despite the limited sample size, it is evident that there is a significant increase in the incidence of angioinvasive maxillofacial fungal infections in diabetic patients treated for SARS-CoV-2 with a strong association with corticosteroid administration.
    Language English
    Publishing date 2021-03-06
    Publishing country India
    Document type Journal Article
    ZDB-ID 2502352-4
    ISSN 0974-942X ; 0972-8279
    ISSN (online) 0974-942X
    ISSN 0972-8279
    DOI 10.1007/s12663-021-01532-1
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  2. Article: Report of a Case of Tuberculosis of Mandibular Condyle in a Patient on Haemodialysis.

    Krishna, Shreya / Moorthy, Aditya / Bachalli, Prithvi / Gaikwad, Rohith / Bhat, Prashanth / Hegde, Shobha

    Journal of maxillofacial and oral surgery

    2019  Volume 19, Issue 4, Page(s) 517–519

    Language English
    Publishing date 2019-06-11
    Publishing country India
    Document type Case Reports
    ZDB-ID 2502352-4
    ISSN 0974-942X ; 0972-8279
    ISSN (online) 0974-942X
    ISSN 0972-8279
    DOI 10.1007/s12663-019-01254-5
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  3. Article ; Online: COVID-associated rhinocerebral mucormycosis: a retrospective analysis of presentation and outcomes.

    Moorthy, Aditya / Nayak, Tulasi / Bachalli, Prithvi S / Tripathi, Krishna Kant / Dutt, Sunil Narayan / Kale, Preeti / Bhat, Prashanth / Suresh, Praveen K / Gaikwad, Rohith / Raju, Arjun / Krishna, Shreya / Conjeevaram, Arvind / Mehta, Sushma / Anil-Kumar, Abhinav / Haldipur, Deepak

    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

    2022  Volume 280, Issue 2, Page(s) 713–721

    Abstract: Objectives: To comprehensively analyse the disease presentation and mortality of COVID-associated rhino-orbito-cerebral mucormycosis.: Methods: A retrospective analysis of the demographics, clinical and radiographic findings was performed. A binary ... ...

    Abstract Objectives: To comprehensively analyse the disease presentation and mortality of COVID-associated rhino-orbito-cerebral mucormycosis.
    Methods: A retrospective analysis of the demographics, clinical and radiographic findings was performed. A binary logistic regression analysis was performed to examine the survival of patients with mucormycosis from hypothesised predictors.
    Results: A total of 202 patients were included in this study. Statistical significance was demonstrated in the predilection to the male gender, recent history of SARS-COV-2, history of use of corticosteroid and hyperglycemia in this cohort of CAM. The mortality rate was 18.31%. Advanced age, raised HbA1c and intra-orbital extension were found to be predictors adversely affecting survival.
    Conclusion: Early diagnosis, aggressive surgical therapy, early and appropriate medical therapy can help improve outcomes.
    Level of evidence: Level 4.
    MeSH term(s) Humans ; Male ; Mucormycosis/complications ; Mucormycosis/diagnosis ; Mucormycosis/therapy ; Retrospective Studies ; COVID-19/complications ; SARS-CoV-2 ; Nose ; Orbital Diseases/diagnosis ; Orbital Diseases/therapy ; Antifungal Agents/therapeutic use
    Chemical Substances Antifungal Agents
    Language English
    Publishing date 2022-07-18
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1017359-6
    ISSN 1434-4726 ; 0937-4477
    ISSN (online) 1434-4726
    ISSN 0937-4477
    DOI 10.1007/s00405-022-07544-y
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  4. Article: Primary squamous cell carcinoma of the submandibular salivary gland: a rare entity.

    Gaikwad, Rohith V / Kumaraswamy, S V / Keerthi, R

    Journal of maxillofacial and oral surgery

    2011  Volume 14, Issue Suppl 1, Page(s) 57–59

    Abstract: Salivary gland tumors make up about 3% of all neoplasms of the head and neck. Salivary gland tumors vary widely in histopathological appearance, thus it prompted the development of a revised histopathological classification of tumours. Malignant tumors ... ...

    Abstract Salivary gland tumors make up about 3% of all neoplasms of the head and neck. Salivary gland tumors vary widely in histopathological appearance, thus it prompted the development of a revised histopathological classification of tumours. Malignant tumors can arise in the major salivary glands or numerous minor salivary glands lining the mucosa of the upper aerodigestive tract. This case highlights one of the rare variants of primary squamous carcinoma of the sub mandibular salivary gland and the management of submandibular salivary gland malignancies.
    Language English
    Publishing date 2011-10-14
    Publishing country India
    Document type Case Reports
    ZDB-ID 2502352-4
    ISSN 0974-942X ; 0972-8279
    ISSN (online) 0974-942X
    ISSN 0972-8279
    DOI 10.1007/s12663-011-0285-y
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  5. Article: Decompression and cystectomy of the odontogenic keratocysts of the mandible: a clinical study.

    Gaikwad, Rohith / Kumaraswamy, S V / Keerthi, R

    Journal of maxillofacial and oral surgery

    2009  Volume 8, Issue 1, Page(s) 47–51

    Abstract: Objectives: Owing to the aggressive nature of OKC's if one could stop or even reverse the growth of the cyst with a simple procedure like decompression, regardless of the histologic type, it would be an alternative to radical and disfiguring surgery.: ...

    Abstract Objectives: Owing to the aggressive nature of OKC's if one could stop or even reverse the growth of the cyst with a simple procedure like decompression, regardless of the histologic type, it would be an alternative to radical and disfiguring surgery.
    Methods: Eight patients who were diagnosed with Odontogenic keratocyst of the mandible were chosen and the first stage of treatment being, insertion of the decompression stent into the most prominent or dependent part of the cystic cavity. Then based on assessment of regular second monthly OPG radiograph the second stage ie. Enucleation of the cyst and treatment of the cystic cavity with Carnoy's solution was carried out, when the size of the cystic cavity had decreased.
    Results: The radiographs of all the patients were analyzed at a two month interval and compared with the pre operative radiograph. The percentage of change in radiodensity of the lesion ranged from 35.15% to 66.16% with a mean decrease of 53.85%. This also indicated that the quantum of bone regeneration which occurred simultaneously and as observed during the cystectomy procedure was commendable.
    Conclusion: Reduction of surgical morbidity while preserving anatomy and function, is the greatest advantage of decompression, however one should not forget the emphasis on the value of long term studies needed to be carried out with regular follow-up, to keep a check on those patients treated with decompression.
    Language English
    Publishing date 2009-06-10
    Publishing country India
    Document type Journal Article
    ZDB-ID 2502352-4
    ISSN 0974-942X ; 0972-8279
    ISSN (online) 0974-942X
    ISSN 0972-8279
    DOI 10.1007/s12663-009-0012-0
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  6. Article ; Online: Head and neck squamous cell carcinoma in chronic areca nut chewing Indian women: Case series and review of literature.

    Muttagi, Sidramesh Shivanand / Chaturvedi, Pankaj / Gaikwad, Rohith / Singh, Bikramjit / Pawar, Prashant

    Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology

    2012  Volume 33, Issue 1, Page(s) 32–35

    Abstract: Background: Head and neck squamous cell carcinoma (HNSCC) is an important public health problem in India. Several risk factors such as tobacco, human papilloma virus, alcohol, areca nut usage have been extensively studied as causative agents. Though ... ...

    Abstract Background: Head and neck squamous cell carcinoma (HNSCC) is an important public health problem in India. Several risk factors such as tobacco, human papilloma virus, alcohol, areca nut usage have been extensively studied as causative agents. Though Areca nut chewing is known cause of oral cancer, its association with hypopharynx cancer has not been previously reported. Since areca nut is mostly consumed along with tobacco, it is uncommon to find patients who consume the areca nut alone.
    Materials and methods: This is a prospective case series of ten women who presented to us with HNSCC with history of chewing of areca nut alone for several years. We have excluded all those cases where areca nut was consumed along with tobacco in any form. The data were prospectively collected with regard to clinical parameters, duration and frequency of areca nut usage, the socio-economic status and education level.
    Results: All ten females had varying degree of submucous fibrosis and coexisting squamous cell carcinoma either in the oral cavity or hypopharynx. Submucous fibrosis was characterized by burning mouth, unhealthy oral mucosa, buried third molars, trismus, poor oral hygiene, etc. The disease presented in an advanced stage in majority of the cases. All patients were unaware of areca nut's deleterious effects.
    Conclusion: Areca nut chewing is an important risk factor for HNSCC in females. Despite plethora of information, little importance is given to areca nut control in cancer prevention campaigns in India.
    Language English
    Publishing date 2012-07-01
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2181724-8
    ISSN 0975-2129 ; 0975-2129
    ISSN (online) 0975-2129
    ISSN 0975-2129
    DOI 10.4103/0971-5851.96966
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  7. Article: Head and neck squamous cell carcinoma in chronic areca nut chewing Indian women: Case series and review of literature

    Muttagi, Sidramesh Shivanand / Chaturvedi, Pankaj / Gaikwad, Rohith / Singh, Bikramjit / Pawar, Prashant

    Indian Journal of Medical and Paediatric Oncology

    2012  Volume 33, Issue 01, Page(s) 32–35

    Abstract: Background: Head and neck squamous cell carcinoma (HNSCC) is an important public health problem in India. Several risk factors such as tobacco, human papilloma virus, alcohol, areca nut usage have been extensively studied as causative agents. Though ... ...

    Abstract Background: Head and neck squamous cell carcinoma (HNSCC) is an important public health problem in India. Several risk factors such as tobacco, human papilloma virus, alcohol, areca nut usage have been extensively studied as causative agents. Though Areca nut chewing is known cause of oral cancer, its association with hypopharynx cancer has not been previously reported. Since areca nut is mostly consumed along with tobacco, it is uncommon to find patients who consume the areca nut alone.
    Materials and Methods: This is a prospective case series of ten women who presented to us with HNSCC with history of chewing of areca nut alone for several years. We have excluded all those cases where areca nut was consumed along with tobacco in any form. The data were prospectively collected with regard to clinical parameters, duration and frequency of areca nut usage, the socio-economic status and education level.
    Results: All ten females had varying degree of submucous fibrosis and coexisting squamous cell carcinoma either in the oral cavity or hypopharynx. Submucous fibrosis was characterized by burning mouth, unhealthy oral mucosa, buried third molars, trismus, poor oral hygiene, etc. The disease presented in an advanced stage in majority of the cases. All patients were unaware of areca nut′s deleterious effects.
    Conclusion: Areca nut chewing is an important risk factor for HNSCC in females. Despite plethora of information, little importance is given to areca nut control in cancer prevention campaigns in India.
    Keywords Areca nut ; oral cancer ; oral submucous fibrosis ; potentially malignant lesion
    Language English
    Publishing date 2012-01-01
    Publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2181724-8
    ISSN 0975-2129 ; 0971-5851 ; 0975-2129
    ISSN (online) 0975-2129
    ISSN 0971-5851 ; 0975-2129
    DOI 10.4103/0971-5851.96966
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