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  1. Article ; Online: Visuo-spatial attention and semantic memory competition in the parietal cortex.

    Capotosto, Paolo / Sulpizio, Valentina / Galati, Gaspare / Baldassarre, Antonello

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 6218

    Abstract: Neuroimaging studies associate specific functional roles to distinct brain regions investigating separate cognitive processes using dedicated tasks. For example, using both correlative (i.e., fMRI) and causal (i.e., TMS) approaches it has been shown the ... ...

    Abstract Neuroimaging studies associate specific functional roles to distinct brain regions investigating separate cognitive processes using dedicated tasks. For example, using both correlative (i.e., fMRI) and causal (i.e., TMS) approaches it has been shown the involvement of intra-parietal sulcus (IPS), as part of the dorsal attention network, in spatial attentional tasks as well as the importance of the angular gyrus (AG), as part of the default mode network, during the selection of relevant information in semantic memory. Nonetheless, in our daily life attention and semantic memory are rarely needed in isolation. In the present TMS study we investigate how the brain combines attentional and semantic memory demands in a single task. Results showed that, compared to a pseudo-TMS, stimulation of IPS, but not AG, affects behavioral performance, thus suggesting its preponderant role in such a combined task. Moreover, the lack of difference between the effect of IPS and AG stimulations seems to suggest that the two regions may be coactivated or that a third-party source might indirectly mediate the interaction between the two networks.
    MeSH term(s) Transcranial Magnetic Stimulation/methods ; Semantics ; Parietal Lobe/physiology ; Memory/physiology ; Brain/physiology ; Brain Mapping ; Magnetic Resonance Imaging
    Language English
    Publishing date 2023-04-17
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-33533-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Semantic interference and facilitation in picture naming: The effects of type of impairment and compensatory strategies.

    Nappo, Raffaele / Galati, Gaspare / Bureca, Ivana / Romani, Cristina

    Cognitive neuropsychology

    2023  Volume 39, Issue 5-8, Page(s) 325–355

    Abstract: We assessed effects of semantic interference in people with aphasia (PWA). Two naming tasks (continuous naming and cyclic blocking) were contrasted with tasks which required suppression of competitors but minimized lexical access (probe task) or required ...

    Abstract We assessed effects of semantic interference in people with aphasia (PWA). Two naming tasks (continuous naming and cyclic blocking) were contrasted with tasks which required suppression of competitors but minimized lexical access (probe task) or required extra-lexical mechanisms of control (Stroop task). In continuous naming, some PWA showed increased interference compared to control participants, with slower RTs and increased omissions. Others showed normal or weaker interference effects in terms of RTs but increased semantic errors. Patterns were consistent only between naming tasks. We explain results by assuming that some PWA are slow at implementing mechanisms of control/selection which weed-out competitors. Others, instead, will have activation difficulties which will induce them to lower the threshold needed for selection. Results highlight how different kinds of brain damage may induce different compensatory strategies and how semantic relatedness may induce both interference and facilitation. Implications for models of lexical selection are discussed.
    MeSH term(s) Humans ; Semantics ; Aphasia
    Language English
    Publishing date 2023-03-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 226406-7
    ISSN 1464-0627 ; 0264-3294
    ISSN (online) 1464-0627
    ISSN 0264-3294
    DOI 10.1080/02643294.2023.2189004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Neural sensitivity to translational self- and object-motion velocities.

    Sulpizio, Valentina / von Gal, Alessandro / Galati, Gaspare / Fattori, Patrizia / Galletti, Claudio / Pitzalis, Sabrina

    Human brain mapping

    2024  Volume 45, Issue 1, Page(s) e26571

    Abstract: The ability to detect and assess world-relative object-motion is a critical computation performed by the visual system. This computation, however, is greatly complicated by the observer's movements, which generate a global pattern of motion on the ... ...

    Abstract The ability to detect and assess world-relative object-motion is a critical computation performed by the visual system. This computation, however, is greatly complicated by the observer's movements, which generate a global pattern of motion on the observer's retina. How the visual system implements this computation is poorly understood. Since we are potentially able to detect a moving object if its motion differs in velocity (or direction) from the expected optic flow generated by our own motion, here we manipulated the relative motion velocity between the observer and the object within a stationary scene as a strategy to test how the brain accomplishes object-motion detection. Specifically, we tested the neural sensitivity of brain regions that are known to respond to egomotion-compatible visual motion (i.e., egomotion areas: cingulate sulcus visual area, posterior cingulate sulcus area, posterior insular cortex [PIC], V6+, V3A, IPSmot/VIP, and MT+) to a combination of different velocities of visually induced translational self- and object-motion within a virtual scene while participants were instructed to detect object-motion. To this aim, we combined individual surface-based brain mapping, task-evoked activity by functional magnetic resonance imaging, and parametric and representational similarity analyses. We found that all the egomotion regions (except area PIC) responded to all the possible combinations of self- and object-motion and were modulated by the self-motion velocity. Interestingly, we found that, among all the egomotion areas, only MT+, V6+, and V3A were further modulated by object-motion velocities, hence reflecting their possible role in discriminating between distinct velocities of self- and object-motion. We suggest that these egomotion regions may be involved in the complex computation required for detecting scene-relative object-motion during self-motion.
    MeSH term(s) Humans ; Motion Perception/physiology ; Brain Mapping ; Motion ; Gyrus Cinguli ; Neocortex ; Photic Stimulation/methods
    Language English
    Publishing date 2024-01-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1197207-5
    ISSN 1097-0193 ; 1065-9471
    ISSN (online) 1097-0193
    ISSN 1065-9471
    DOI 10.1002/hbm.26571
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Effects of Fed policy rate forecasts on real yields and inflation expectations at the zero lower bound

    Galati, Gabriele / Moessner, Richhild

    Economics letters. 2021 Jan., v. 198

    2021  

    Abstract: Surprises in policy rate forecasts from the Fed’s Summary of Economic Projections significantly affected real yields at the zero lower bound. By contrast, we find no significant impact on long-term inflation expectations and thereby monetary policy ... ...

    Abstract Surprises in policy rate forecasts from the Fed’s Summary of Economic Projections significantly affected real yields at the zero lower bound. By contrast, we find no significant impact on long-term inflation expectations and thereby monetary policy credibility.
    Keywords inflation ; monetary policy ; yields
    Language English
    Dates of publication 2021-01
    Publishing place Elsevier B.V.
    Document type Article
    Note NAL-light
    ISSN 0165-1765
    DOI 10.1016/j.econlet.2020.109654
    Database NAL-Catalogue (AGRICOLA)

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  5. Article ; Online: Interhemispheric interplay between the left and right premotor cortex during grasping as assessed by dynamic causal modelling.

    Bencivenga, Federica / Tullo, Maria Giulia / Sulpizio, Valentina / Galati, Gaspare

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 4958

    Abstract: Research on the contribution of the ipsilateral hemisphere to unilateral movements, and how it is mediated by transcallosal connections, has so far provided contradictory findings. By using dynamic causal modelling (DCM) and Parametric Empirical Bayes ... ...

    Abstract Research on the contribution of the ipsilateral hemisphere to unilateral movements, and how it is mediated by transcallosal connections, has so far provided contradictory findings. By using dynamic causal modelling (DCM) and Parametric Empirical Bayes analyses applied to fMRI data, we sought to describe effective connectivity during pantomimed and imagined right-hand grasping within the grasping network, namely the anterior intraparietal sulcus, ventral and dorsal (PMd) premotor cortex, supplementary motor area and primary motor cortex (M1). The two-fold aim of the present work was to explore a) whether right and left parieto-frontal areas show similar connectivity couplings, and b) the interhemispheric dynamics between these regions across the two hemispheres. We detected a network architecture comparable across hemispheres during executed but not imagined grasping movements. Furthermore, during pantomimed grasping the interhemispheric crosstalk was mainly driven by premotor areas: we found an inhibitory influence from the right PMd toward the left premotor and motor areas and excitatory couplings between homologous ventral premotor and supplementary motor regions. Overall, our results support the view that dissociable components of unilateral grasping execution are encoded by a non-lateralized set of brain areas complexly intertwined by interhemispheric dynamics, whereas motor imagery obeys different principles.
    MeSH term(s) Motor Cortex/diagnostic imaging ; Bayes Theorem ; Brain ; Movement ; Hand ; Brain Mapping ; Magnetic Resonance Imaging
    Language English
    Publishing date 2023-03-27
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-31602-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Hypotension and optimization of heart failure therapy after a recent hospitalization for heart failure: When the going gets tough, the tough get going.

    Galati, Giuseppe / Germanova, Olga / Pedretti, Roberto Franco Enrico / Ambrosio, Giuseppe

    International journal of cardiology

    2023  Volume 388, Page(s) 131118

    MeSH term(s) Humans ; Hospitalization ; Heart Failure/diagnosis ; Heart Failure/epidemiology ; Heart Failure/therapy ; Hypotension ; Anti-Arrhythmia Agents ; Stroke Volume
    Chemical Substances Anti-Arrhythmia Agents
    Language English
    Publishing date 2023-06-14
    Publishing country Netherlands
    Document type Editorial ; Comment
    ZDB-ID 779519-1
    ISSN 1874-1754 ; 0167-5273
    ISSN (online) 1874-1754
    ISSN 0167-5273
    DOI 10.1016/j.ijcard.2023.131118
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Effect of optic flow on spatial updating: insight from an immersive virtual reality study.

    Cardelli, Lisa / Tullo, Maria Giulia / Galati, Gaspare / Sulpizio, Valentina

    Experimental brain research

    2023  Volume 241, Issue 3, Page(s) 865–874

    Abstract: Self-motion information is required to keep track of where we are with respect to our environment (spatial updating). Visual signals such as optic flow are relevant to provide information about self-motion, especially in the absence of vestibular and/or ... ...

    Abstract Self-motion information is required to keep track of where we are with respect to our environment (spatial updating). Visual signals such as optic flow are relevant to provide information about self-motion, especially in the absence of vestibular and/or proprioceptive cues generated by physical movement. However, the role of optic flow on spatial updating is still debated. A virtual reality system based on a head-mounted display was used to allow participants to experience a self-motion sensation within a naturalistic environment in the absence of physical movement. We asked participants to keep track of spatial positions of a target during simulated self-motion while manipulating the availability of optic flow coming from the lower part of the environment (ground plane). In each trial, the ground could be a green lawn (optic flow ON) or covered in snow (optic flow OFF). We observed that the lack of optic flow on the ground had a detrimental effect on spatial updating. Furthermore, we explored the interaction between the optic flow availability and different characteristics of self-motion: we observed that increasing self-motion speed had a detrimental effect on spatial updating, especially in the absence of optic flow, while self-motion direction (leftward, forward, rightward) and path (translational and curvilinear) had no statically significant effect. Overall, we demonstrated that, in the absence of some idiothetic cues, the optic flow provided by the ground has a dominant role for the self-motion estimation and, hence, for the ability to update the spatial relationships between one's position and the position of the surrounding objects.
    MeSH term(s) Humans ; Motion Perception ; Optic Flow ; Photic Stimulation/methods ; Movement ; Cues ; Virtual Reality
    Language English
    Publishing date 2023-02-13
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1201-4
    ISSN 1432-1106 ; 0014-4819
    ISSN (online) 1432-1106
    ISSN 0014-4819
    DOI 10.1007/s00221-023-06567-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Proprotein convertase subtilisin kexin type 9 and main artery atherosclerosis in patients with arterial hypertension.

    Vukolova, Yulia / Gubareva, Irina / Galati, Giuseppe / Germanova, Olga

    Minerva cardiology and angiology

    2022  Volume 71, Issue 2, Page(s) 129–134

    Abstract: Background: Aim of our investigation is to study the relationship between the level of proprotein convertase subtilisin kexin type 9 (PCSK9) and atherosclerotic process of coronary and brachiocephalic arteries in patients with arterial hypertension (AH). ...

    Abstract Background: Aim of our investigation is to study the relationship between the level of proprotein convertase subtilisin kexin type 9 (PCSK9) and atherosclerotic process of coronary and brachiocephalic arteries in patients with arterial hypertension (AH).
    Methods: Our investigation was performed in regional railway hospital. In our investigation we included 161 male train drivers who had AH with achieved target grades 1-2. All patients were performed laboratory tests including cholesterol, LDL-C, triglycerides, glucose, hemostasiograms, PCSK9. Patients were divided into groups up to the PCSK9 level: in group 1 (N.=41) we included patients with PCSK9 level 108-250 ng/mL; group 2 (N.=37) 251-400 ng/mL; group 3 (N.=45) 420-560 ng/mL and group 4 (N.=38) 580-860 ng/mL. All patients were performed coronary angiography, ultrasound Doppler of brachiocephalic arteries, electrocardiography, transthoracic echocardiography.
    Results: The groups of the patients were identical in age, Body Mass Index, triglycerides, LDL-C, glucose, cholesterol levels. Also, there was no significant difference in the dependence of PCSK9 level on smoking status (χ
    Conclusions: The level of PCSK9 in male patients is an additional cardiovascular risk factor independent from the traditional risk factors. The PCSK9 level is correlated with atherosclerotic severity process of brachiocephalic arteries (P=0.08; r=0.2). The concentration of PCSK9 in the blood serum more than 580 ng/mL in patients with AH determines more severe coronary arteries atherosclerosis. If more the level of PCSK9 than more cardiovascular risk (P=0.002).
    MeSH term(s) Humans ; Male ; Proprotein Convertase 9 ; Carotid Intima-Media Thickness ; Coronary Artery Disease/complications ; Coronary Artery Disease/diagnostic imaging ; Atherosclerosis ; Hypertension/complications ; Arteries ; Triglycerides ; Glucose ; Subtilisins
    Chemical Substances PCSK9 protein, human (EC 3.4.21.-) ; Proprotein Convertase 9 (EC 3.4.21.-) ; Triglycerides ; Glucose (IY9XDZ35W2) ; Subtilisins (EC 3.4.21.-)
    Language English
    Publishing date 2022-04-14
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 3059238-0
    ISSN 2724-5772
    ISSN (online) 2724-5772
    DOI 10.23736/S2724-5683.22.06008-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Atrial fibrillation as a new independent risk factor for thromboembolic events: hemodynamics and vascular consequence of long ventricular pauses.

    Germanova, Olga / Galati, Giuseppe / Germanov, Andrey / Stefanidis, Alexandros

    Minerva cardiology and angiology

    2022  Volume 71, Issue 2, Page(s) 175–181

    Abstract: Background: Atrial fibrillation (AF) is a leading risk factor of arterial thromboembolic events. Aim is to study the main arteries hemodynamics and kinetics in AF and to propose the functional classification of AF.: Methods: We included 188 patients ( ...

    Abstract Background: Atrial fibrillation (AF) is a leading risk factor of arterial thromboembolic events. Aim is to study the main arteries hemodynamics and kinetics in AF and to propose the functional classification of AF.
    Methods: We included 188 patients (80 as the control). We performed 24-hours ECG monitoring, blood lipids analysis, echocardiography, stress echocardiography, coronary angiography, renal arteries angiography, ultrasound Doppler of brachiocephalic arteries, abdominal aorta branches, renal arteries, lower extremities arteries, sphygmography. Patients were divided into 3 groups up to the duration of maximum pauses between ventricular complexes in AF: 1) with a pause <1 second (64); 2) with a pause of ≥1, but <2 seconds (62); 3) ≥2 seconds (62). We analyzed the thromboembolic events within 1 year.
    Results: We observed the increase of linear blood flow velocity and volume flow in patients with AF during the spreading of the wave after a long pause between ventricles' contractions. The longer the pause between the ventricles' contractions, the more increase of arteries kinetics parameters is observed. The most frequent incidence of thromboembolic events within 1 year was in group 3.
    Conclusions: We propose a functional classification of AF: 1) AF with the pauses of less than 1 second; 2) more 1, but less than 2 seconds; and 3) 2 or more seconds. The most unfavorable is AF with pauses of 2 seconds or more. We supplemented the CHA<inf>2</inf>DS<inf>2</inf>-VASc Score with the new independent risk factor - type of AF - in accordance with the maximum duration of pauses between cardiac cycles.
    MeSH term(s) Humans ; Atrial Fibrillation/complications ; Thromboembolism/epidemiology ; Thromboembolism/etiology ; Risk Factors ; Heart ; Hemodynamics
    Language English
    Publishing date 2022-03-25
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 3059238-0
    ISSN 2724-5772
    ISSN (online) 2724-5772
    DOI 10.23736/S2724-5683.22.06000-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Game theoretical trajectory planning enhances social acceptability of robots by humans.

    Galati, Giada / Primatesta, Stefano / Grammatico, Sergio / Macrì, Simone / Rizzo, Alessandro

    Scientific reports

    2022  Volume 12, Issue 1, Page(s) 21976

    Abstract: Since humans and robots are increasingly sharing portions of their operational spaces, experimental evidence is needed to ascertain the safety and social acceptability of robots in human-populated environments. Although several studies have aimed at ... ...

    Abstract Since humans and robots are increasingly sharing portions of their operational spaces, experimental evidence is needed to ascertain the safety and social acceptability of robots in human-populated environments. Although several studies have aimed at devising strategies for robot trajectory planning to perform safe motion in populated environments, a few efforts have measured to what extent a robot trajectory is accepted by humans. Here, we present a navigation system for autonomous robots that ensures safety and social acceptability of robotic trajectories. We overcome the typical reactive nature of state-of-the-art trajectory planners by leveraging non-cooperative game theory to design a planner that encapsulates human-like features of preservation of a personal space, recognition of groups, sequential and strategized decision making, and smooth obstacle avoidance. Social acceptability is measured through a variation of the Turing test administered in the form of a survey questionnaire to a pool of 691 participants. Comparison terms for our tests are a state-of-the-art navigation algorithm (Enhanced Vector Field Histogram, VFH) and purely human trajectories. While all participants easily recognized the non-human nature of VFH-generated trajectories, the distinction between game-theoretical trajectories and human ones were hardly revealed. Our results mark a strong milestone toward the full integration of robots in social environments.
    MeSH term(s) Humans ; Robotics ; Algorithms ; Game Theory ; Motion ; Personal Space
    Language English
    Publishing date 2022-12-20
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-022-25438-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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