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  1. Article ; Online: MACE in COPD: addressing cardiopulmonary risk.

    Hurst, John R / Gale, Chris P

    The Lancet. Respiratory medicine

    2024  Volume 12, Issue 5, Page(s) 345–348

    MeSH term(s) Humans ; Pulmonary Disease, Chronic Obstructive/epidemiology ; Myocardial Infarction/epidemiology ; Myocardial Infarction/prevention & control ; Risk Factors
    Language English
    Publishing date 2024-03-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2686754-0
    ISSN 2213-2619 ; 2213-2600
    ISSN (online) 2213-2619
    ISSN 2213-2600
    DOI 10.1016/S2213-2600(24)00038-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Defining the need for cardiovascular event definitions.

    Bhatty, Asad / Wilkinson, Chris / Sydes, Matt / Gale, Chris P

    European heart journal. Quality of care & clinical outcomes

    2024  Volume 10, Issue 2, Page(s) 105–107

    MeSH term(s) Humans ; Cardiovascular Diseases/epidemiology
    Language English
    Publishing date 2024-02-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 2823451-0
    ISSN 2058-1742 ; 2058-5225
    ISSN (online) 2058-1742
    ISSN 2058-5225
    DOI 10.1093/ehjqcco/qcae008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Outcomes following major bleeding in atrial fibrillation.

    Nadarajah, Ramesh / Gale, Chris P

    European heart journal. Quality of care & clinical outcomes

    2021  Volume 7, Issue 2, Page(s) 119–120

    MeSH term(s) Atrial Fibrillation/complications ; Atrial Fibrillation/epidemiology ; Hemorrhage/epidemiology ; Hemorrhage/etiology ; Humans ; Warfarin
    Chemical Substances Warfarin (5Q7ZVV76EI)
    Language English
    Publishing date 2021-01-11
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 2823451-0
    ISSN 2058-1742 ; 2058-5225
    ISSN (online) 2058-1742
    ISSN 2058-5225
    DOI 10.1093/ehjqcco/qcaa096
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Collateral cardiovascular damage during the COVID-19 pandemic.

    Nadarajah, Ramesh / Gale, Chris P

    Nature reviews. Cardiology

    2021  Volume 19, Issue 2, Page(s) 81–82

    MeSH term(s) COVID-19 ; Cardiovascular System ; Heart ; Humans ; Pandemics ; SARS-CoV-2
    Language English
    Publishing date 2021-11-29
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2490375-9
    ISSN 1759-5010 ; 1759-5002
    ISSN (online) 1759-5010
    ISSN 1759-5002
    DOI 10.1038/s41569-021-00661-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Using routinely collected health record data for the earlier detection of heart failure with preserved ejection fraction: FIND-HFpEF.

    Nadarajah, Ramesh / Nakao, Yoko M / Wu, Jianhua / Gale, Chris P

    European heart journal

    2023  Volume 44, Issue 33, Page(s) 3113–3115

    MeSH term(s) Humans ; Heart Failure/diagnosis ; Stroke Volume ; Ventricular Function, Left ; Prognosis
    Language English
    Publishing date 2023-08-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 603098-1
    ISSN 1522-9645 ; 0195-668X
    ISSN (online) 1522-9645
    ISSN 0195-668X
    DOI 10.1093/eurheartj/ehad440
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Exacerbating the burden of cardiovascular disease: how can we address cardiopulmonary risk in individuals with chronic obstructive pulmonary disease?

    Shrikrishna, Dinesh / Taylor, Clare J / Stonham, Carol / Gale, Chris P

    European heart journal

    2023  Volume 45, Issue 4, Page(s) 247–249

    MeSH term(s) Humans ; Cardiovascular Diseases/prevention & control ; Pulmonary Disease, Chronic Obstructive/complications ; Heart
    Language English
    Publishing date 2023-10-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 603098-1
    ISSN 1522-9645 ; 0195-668X
    ISSN (online) 1522-9645
    ISSN 0195-668X
    DOI 10.1093/eurheartj/ehad669
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Regional differences in ST-segment elevation myocardial infarction care and outcomes: a call for multi-national cardiovascular registries.

    Aktaa, Suleman / Gale, Chris P

    European heart journal. Quality of care & clinical outcomes

    2020  Volume 7, Issue 1, Page(s) 1–2

    MeSH term(s) Humans ; Registries ; ST Elevation Myocardial Infarction/epidemiology ; ST Elevation Myocardial Infarction/therapy
    Language English
    Publishing date 2020-09-02
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 2823451-0
    ISSN 2058-1742 ; 2058-5225
    ISSN (online) 2058-1742
    ISSN 2058-5225
    DOI 10.1093/ehjqcco/qcaa066
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Inequalities in reperfusion therapy for STEMI.

    Gale, Chris P

    European heart journal. Quality of care & clinical outcomes

    2016  Volume 2, Issue 1, Page(s) 4–5

    Language English
    Publishing date 2016-01-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2823451-0
    ISSN 2058-1742 ; 2058-5225
    ISSN (online) 2058-1742
    ISSN 2058-5225
    DOI 10.1093/ehjqcco/qcv031
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  9. Article ; Online: Illness perceptions and health literacy are strongly associated with health-related quality of life, anxiety, and depression in patients with coronary heart disease: results from the EUROASPIRE V cross-sectional survey.

    Jennings, C S / Astin, F / Prescott, E / Hansen, T / Gale Chris, P / De Bacquer, D

    European journal of cardiovascular nursing

    2022  Volume 22, Issue 7, Page(s) 719–729

    Abstract: Aims: To (1) Describe the sociodemographic and risk factor profiles of a sample of patients with coronary disease, (2) Explore associations between illness perceptions and health literacy with sociodemographic characteristics and risk factors, health- ... ...

    Abstract Aims: To (1) Describe the sociodemographic and risk factor profiles of a sample of patients with coronary disease, (2) Explore associations between illness perceptions and health literacy with sociodemographic characteristics and risk factors, health-related quality of life (HRQoL), anxiety, and depression.
    Methods and results: Conducted as part of the ESC Prevention of CVD Project and EUROASPIRE V survey, patients were consecutively and retrospectively identified 6 months to 2 years after an acute event or elective procedure from 12 countries and interviewed. Three thousand four hundred and eight participants (76% male, mean age 64 years) were recruited, 16% were smokers, 38% obese, 60% physically inactive, and 41% hypertensive. Forty percent had attended cardiac rehabilitation. More threatening illness perceptions were associated with female gender (P < 0.0001), lower income (P < 0.0001), lower education (P = 0.02), obesity (P < 0.0001), sedentary behaviour (P < 0.0001), and diabetes (P < 0.0001). Poorer health literacy was associated with obesity (P = 0.02) and sedentary behaviour (P = 0.0001). Threatening illness perceptions were strongly associated with anxiety, depression, and poorer ratings of HRQoL after multivariable adjustment (all P < 0.001). Poor health literacy was associated with anxiety and depression (P < 0.0001) and poorer ratings of HRQoL (HeartQol scores P = 0.03). Results were consistent across regions of Europe, age, gender, and socio-economic strata.
    Conclusions: Interventions like cardiac rehabilitation should be targeted at vulnerable groups given the strong associations between more threatening illness perceptions, lower health literacy, lower HRQoL, and higher levels of anxiety and depression. The delivery and content of these interventions should be accessible for those with low health literacy.
    MeSH term(s) Humans ; Male ; Female ; Middle Aged ; Quality of Life ; Cross-Sectional Studies ; Health Literacy ; Depression ; Retrospective Studies ; Anxiety ; Coronary Artery Disease ; Obesity
    Language English
    Publishing date 2022-11-07
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2151245-0
    ISSN 1873-1953 ; 1474-5151
    ISSN (online) 1873-1953
    ISSN 1474-5151
    DOI 10.1093/eurjcn/zvac105
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Long-term survival benefit of ramipril in patients with acute myocardial infarction complicated by heart failure.

    Wu, Jianhua / Hall, Alistair S / Gale, Chris P

    Heart (British Cardiac Society)

    2021  Volume 107, Issue 5, Page(s) 389–395

    Abstract: Aims: ACE inhibition reduces mortality and morbidity in patients with heart failure after acute myocardial infarction (AMI). However, there are limited randomised data about the long-term survival benefits of ACE inhibition in this population.: ... ...

    Abstract Aims: ACE inhibition reduces mortality and morbidity in patients with heart failure after acute myocardial infarction (AMI). However, there are limited randomised data about the long-term survival benefits of ACE inhibition in this population.
    Methods: In 1993, the Acute Infarction Ramipril Efficacy (AIRE) study randomly allocated patients with AMI and clinical heart failure to ramipril or placebo. The duration of masked trial therapy in the UK cohort (603 patients, mean age=64.7 years, 455 male patients) was 12.4 and 13.4 months for ramipril (n=302) and placebo (n=301), respectively. We estimated life expectancy and extensions of life (difference in median survival times) according to duration of follow-up (range 0-29.6 years).
    Results: By 9 April 2019, death from all causes occurred in 266 (88.4%) patients in placebo arm and 275 (91.1%) patients in ramipril arm. The extension of life between ramipril and placebo groups was 14.5 months (95% CI 13.2 to 15.8). Ramipril increased life expectancy more for patients with than without diabetes (life expectancy difference 32.1 vs 5.0 months), previous AMI (20.1 vs 4.9 months), previous heart failure (19.5 vs 4.9 months), hypertension (16.6 vs 8.3 months), angina (16.2 vs 5.0 months) and age >65 years (11.3 vs 5.7 months). Given potential treatment switching, the true absolute treatment effect could be underestimated by 28%.
    Conclusion: For patients with clinically defined heart failure following AMI, ramipril results in a sustained survival benefit, and is associated with an extension of life of up to 14.5 months for, on average, 13 months treatment duration.
    MeSH term(s) Aged ; Angiotensin-Converting Enzyme Inhibitors/therapeutic use ; Female ; Heart Failure/drug therapy ; Heart Failure/mortality ; Humans ; Life Expectancy ; Male ; Middle Aged ; Myocardial Infarction/drug therapy ; Myocardial Infarction/mortality ; Ramipril/therapeutic use ; United Kingdom/epidemiology
    Chemical Substances Angiotensin-Converting Enzyme Inhibitors ; Ramipril (L35JN3I7SJ)
    Language English
    Publishing date 2021-01-15
    Publishing country England
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 1303417-0
    ISSN 1468-201X ; 1355-6037
    ISSN (online) 1468-201X
    ISSN 1355-6037
    DOI 10.1136/heartjnl-2020-316823
    Database MEDical Literature Analysis and Retrieval System OnLINE

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