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  1. Article ; Online: Five recommendations for loco-regional treatments of hepatocellular carcinoma during the COVID-19 pandemic.

    Santambrogio, Roberto / Galfrascoli, Elisa / Zappa, Marco Antonio

    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

    2020  Volume 52, Issue 9, Page(s) 950–952

    MeSH term(s) Betacoronavirus ; COVID-19 ; Carcinoma, Hepatocellular ; Coronavirus Infections ; Humans ; Liver Neoplasms ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-06-16
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 1459373-7
    ISSN 1878-3562 ; 1125-8055
    ISSN (online) 1878-3562
    ISSN 1125-8055
    DOI 10.1016/j.dld.2020.05.035
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Gastric cancer after gastric bypass with fundectomy: The possibility for early diagnosis.

    Zappa, Marco Antonio / Giusti, Maria Paola / Galfrascoli, Elisa

    International journal of surgery case reports

    2019  Volume 55, Page(s) 156–159

    Abstract: Introduction: Roux-an-Y gastric bypass (RYGP) is one of the most important bariatric procedures and its results are well known in terms of weight loss and comorbid improvement. The major limitation of this technique is the difficult exploration of the ... ...

    Abstract Introduction: Roux-an-Y gastric bypass (RYGP) is one of the most important bariatric procedures and its results are well known in terms of weight loss and comorbid improvement. The major limitation of this technique is the difficult exploration of the excluded stomach and duodenum. Some Authors are performing the gastric bypass with fundectomy and, according to Literature, it is feasible and effective, with major advantage of explorable gastric pouch.
    Presentation of case: We report the case of a 54-year-old woman affected by obesity (BMI 49 kg/m
    Discussion: Early diagnosis is essential in gastric tumors to ensure a good prognosis and the gold standard is performing gastroscopy with biopsies. With the standard technique is very challenging to perform an OGD and the cancer stage is likely to be advanced at diagnosis, with a bad prognosis for the patient.
    Conclusion: From the clinical case described and the analysis of the Literature, the advantages of this technique are clear, allowing for an easy endoscopic evaluation of gastric walls with the possibility of diagnosing early stage tumors with a better outcome for patients.
    Language English
    Publishing date 2019-02-01
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2210-2612
    ISSN 2210-2612
    DOI 10.1016/j.ijscr.2019.01.040
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The thin red line: ileal angiodysplasia versus SARS-CoV-2-related haemorrhagic enteritis.

    Francese, Massimo / Ferrari, Carlo / Lotti, Marco / Galfrascoli, Elisa / Santambrogio, Roberto / Ierardi, Anna Maria / Gabiati, Claudia / Zappa, Marco Antonio

    Journal of clinical pathology

    2022  

    Language English
    Publishing date 2022-01-17
    Publishing country England
    Document type Letter
    ZDB-ID 80261-x
    ISSN 1472-4146 ; 0021-9746
    ISSN (online) 1472-4146
    ISSN 0021-9746
    DOI 10.1136/jclinpath-2021-207754
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Five recommendations for loco-regional treatments of hepatocellular carcinoma during the COVID-19 pandemic

    Santambrogio, Roberto / Galfrascoli, Elisa / Zappa, Marco Antonio

    Digestive and Liver Disease

    2020  Volume 52, Issue 9, Page(s) 950–952

    Keywords Hepatology ; Gastroenterology ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 2054970-2
    ISSN 1590-8658
    ISSN 1590-8658
    DOI 10.1016/j.dld.2020.05.035
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Laparoscopic ablation therapies for hepatocellular carcinoma: could specific indications for the laparoscopic approach influence the effectiveness?

    Santambrogio, Roberto / Barabino, Matteo / De Nicola, Enrico / Galfrascoli, Elisa / Giovenzana, Marco / Zappa, Marco Antonio

    Updates in surgery

    2020  Volume 72, Issue 2, Page(s) 435–443

    Abstract: Percutaneous thermo-ablation (TA) may be unfeasible for the tumor location: laparoscopic ablation therapies (LATs) are an alternative option. The aim of this study is to assess the efficacy of LATs in the treatment of HCC not eligible for percutaneous TA ...

    Abstract Percutaneous thermo-ablation (TA) may be unfeasible for the tumor location: laparoscopic ablation therapies (LATs) are an alternative option. The aim of this study is to assess the efficacy of LATs in the treatment of HCC not eligible for percutaneous TA or surgical resection. LAT was offered to 503 patients fulfilling at least one of the following criteria: (a) patients with a single nodule or up to three nodules smaller than 3 cm not suitable for surgery; (b) patients not suitable for percutaneous TA; (c) short-term recurrence of HCC (< 3 months). Technical success was achieved with one session in 467 patients (93%). One-month mortality and severe morbidity rates were 0.4% and 2.19%, respectively. During a median follow-up of 38.4 months in the remaining 501 patients, 361 (67%) developed intrahepatic recurrence: it appeared as a local tumor progression (LTP) in 74 cases (15%). Subcapsular lesions showed lower LTP rates (p = 0.008), as well as HCC nodules contiguous to viscera (p = 0.012). In the treatment of HCC, LAT has proved to be a safe and effective technique that enables to treat lesions not eligible for percutaneous approach, with a low morbidity rate.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Carcinoma, Hepatocellular/pathology ; Carcinoma, Hepatocellular/surgery ; Endosonography/methods ; Female ; Follow-Up Studies ; Hepatectomy/methods ; Humans ; Laparoscopy/methods ; Liver Neoplasms/pathology ; Liver Neoplasms/surgery ; Male ; Middle Aged ; Neoplasm Recurrence, Local ; Patient Selection ; Radiofrequency Ablation/methods ; Safety ; Treatment Outcome
    Language English
    Publishing date 2020-04-03
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2572692-4
    ISSN 2038-3312 ; 2038-131X
    ISSN (online) 2038-3312
    ISSN 2038-131X
    DOI 10.1007/s13304-020-00759-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Evolution of Bariatric Surgery in Italy in the Last 11 Years: Data from the SICOB Yearly National Survey.

    Gentileschi, Paolo / Sensi, Bruno / Siragusa, Leandro / Sorge, Roberto / Rispoli, Eliana / Angrisani, Luigi / Galfrascoli, Elisa / Bianciardi, Emanuela / Giusti, Maria Paola / De Luca, Maurizio / Zappa, Marco Antonio

    Obesity surgery

    2023  Volume 33, Issue 3, Page(s) 930–937

    Abstract: Background: Bariatric surgery (BS) is a relatively novel surgical field and is in continuous expansion and evolution.: Purpose: Aim of this study was to report changes in Italian surgical practice in the last decade.: Methods: The Società Italiana ...

    Abstract Background: Bariatric surgery (BS) is a relatively novel surgical field and is in continuous expansion and evolution.
    Purpose: Aim of this study was to report changes in Italian surgical practice in the last decade.
    Methods: The Società Italiana di Chirurgia dell'Obesità (SICOB) conducted annual surveys to cense activity of SICOB centers between 2011 and 2021. Primary outcome was to detect differences in frequency of performance of adjustable gastric banding (AGB), sleeve gastrectomy (SG), Roux-en-Y gastric bypass (RYGB), one anastomosis gastric bypass (OAGB), bilio-pancreatic diversion (BPD), and gastric plication (GP). Secondary outcome was to detect differences in performance of main non-malabsorptive procedures (AGB + SG) and overall bypass procedures (RYGB + OAGB). Geographical differences were also investigated.
    Results: Median response rate was 92%. AGB declined from 36% of procedures in 2011 to 5% in 2021 (p < 0.0001). SG increased from 30% in 2011 to 55% in 2021 (p < 0.0001). RYGB declined from 25 to 12% of procedures (p < 0.0001). OAGB rose from 0% of procedures in 2011 to 15% in 2021 (p < 0.0001). BPD underwent decrease from 6.2 to 0.2% in 2011 and 2021, respectively (p < 0.0001). Main non-malabsorptive procedures significantly decreased while overall bypass procedures remained stable. There were significant differences among regions in performance of SG, RYGB, and OAGB.
    Conclusions: BS in Italy evolved significantly during the past 10 years. AGB underwent a decline, as did BPD and GP which are disappearing and RYGB which is giving way to OAGB. The latter is rising and is the second most-performed procedure after SG which has been confirmed as the preferred procedure by Italian bariatric surgeons.
    MeSH term(s) Humans ; Obesity, Morbid/surgery ; Treatment Outcome ; Bariatric Surgery ; Gastric Bypass/methods ; Gastrectomy/methods ; Italy ; Retrospective Studies
    Language English
    Publishing date 2023-01-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1070827-3
    ISSN 1708-0428 ; 0960-8923
    ISSN (online) 1708-0428
    ISSN 0960-8923
    DOI 10.1007/s11695-022-06435-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Laparoscopic thermoablation for hepatocellular carcinoma in patients with liver cirrhosis: an effective procedure for tricky tumors.

    Santambrogio, Roberto / Barabino, Matteo / D'Alessandro, Valentina / Galfrascoli, Elisa / Zappa, Marco Antonio / Piccolo, Gaetano / Zuin, Massimo / Opocher, Enrico

    Medical oncology (Northwood, London, England)

    2020  Volume 37, Issue 4, Page(s) 32

    Abstract: The optimal treatment for hepatocellular carcinoma (HCC) is surgical resection. However, only a small percentage of patients are amenable to this option. Percutaneous radiofrequency interstitial thermal ablation (TA) proved to be effective in the ... ...

    Abstract The optimal treatment for hepatocellular carcinoma (HCC) is surgical resection. However, only a small percentage of patients are amenable to this option. Percutaneous radiofrequency interstitial thermal ablation (TA) proved to be effective in the treatment of unresectable HCC. Recent advances in laparoscopic ultrasound have improved the accuracy in detecting small intrahepatic HCC nodules missed by pre-operative imaging techniques. Our objective was to evaluate an operative combination of laparoscopic ultrasound with laparoscopic thermoablation (LTA) in the treatment of HCC not amenable to liver resection. The aim of our review was to evaluate the advantages and limits of the laparoscopic approach according the criteria of the evidence-based medicine. LTA of HCC proved to be a safe and effective technique both in the short- and long-term follow-up period. This technique may be indicated in selected cases when the percutaneous approach to the lesion is very difficult or contraindicated.
    MeSH term(s) Adult ; Aged ; Carcinoma, Hepatocellular/complications ; Carcinoma, Hepatocellular/diagnostic imaging ; Carcinoma, Hepatocellular/pathology ; Carcinoma, Hepatocellular/surgery ; Catheter Ablation ; Female ; Humans ; Laparoscopy ; Liver Cirrhosis/complications ; Liver Cirrhosis/diagnostic imaging ; Liver Cirrhosis/pathology ; Liver Cirrhosis/surgery ; Liver Neoplasms/complications ; Liver Neoplasms/diagnostic imaging ; Liver Neoplasms/pathology ; Liver Neoplasms/surgery ; Male ; Middle Aged ; Surgery, Computer-Assisted ; Treatment Outcome ; Ultrasonography, Interventional
    Language English
    Publishing date 2020-03-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1201189-7
    ISSN 1559-131X ; 0736-0118 ; 1357-0560
    ISSN (online) 1559-131X
    ISSN 0736-0118 ; 1357-0560
    DOI 10.1007/s12032-020-1342-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Quality of Life and Gastrointestinal Symptoms Following Laparoscopic Roux-en-Y Gastric Bypass and Laparoscopic Sleeve Gastrectomy: a Systematic Review.

    Rausa, Emanuele / Kelly, Michael E / Galfrascoli, Elisa / Aiolfi, Albero / Cavalcoli, Federica / Turati, Luca / Bonavina, Luigi / Sgroi, Giovanni

    Obesity surgery

    2019  Volume 29, Issue 4, Page(s) 1397–1402

    Abstract: Laparoscopic Roux-en-Y gastric bypass (LRYGB) and laparoscopic sleeve gastrectomy (LSG) are the most common bariatric operations performed worldwide. Quality of life (QoL) is a crucial outcome metric. An electronic systematic search using PubMed, EMBASE, ...

    Abstract Laparoscopic Roux-en-Y gastric bypass (LRYGB) and laparoscopic sleeve gastrectomy (LSG) are the most common bariatric operations performed worldwide. Quality of life (QoL) is a crucial outcome metric. An electronic systematic search using PubMed, EMBASE, and Web of Science of studies comparing QoL after LSG and LRYGB was performed. QoL after both LSG and LRYGB considerably improves regardless the type of surgery. The QoL has a slight downward trend from the second to the fifth year postoperatively, but it remains higher than the baseline. LSG patients are more likely to suffer from gastroesophageal symptoms (GES). GES represent the only significant difference between the two procedures. A routine screening with gastroscopy and 24 h pH metry to help tailor the most appropriate surgical approach is advised.
    MeSH term(s) Gastrectomy/adverse effects ; Gastrectomy/statistics & numerical data ; Gastric Bypass/adverse effects ; Gastric Bypass/statistics & numerical data ; Humans ; Laparoscopy/adverse effects ; Laparoscopy/statistics & numerical data ; Postoperative Complications ; Quality of Life
    Language English
    Publishing date 2019-01-03
    Publishing country United States
    Document type Journal Article ; Systematic Review
    ZDB-ID 1070827-3
    ISSN 1708-0428 ; 0960-8923
    ISSN (online) 1708-0428
    ISSN 0960-8923
    DOI 10.1007/s11695-019-03737-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Prospective Evaluation of Genito-Urinary Function after Laparoscopic Rectal Resection in the Elderly.

    Mari, Giulio / Costanzi, Andrea / Galfrascoli, Elisa / Rosato, Andrea / Crippa, Jacopo / Maggioni, Dario

    Chirurgia (Bucharest, Romania : 1990)

    2016  Volume 111, Issue 4, Page(s) 318–325

    Abstract: Laparoscopic anterior rectal resection with total mesorectal excision is related to sexual and urinary disorders. Anastomotic leak and neo-adjuvant radiation therapy are effective factors in worsening pelvic function. We report a series of 50 elderly ( ... ...

    Abstract Laparoscopic anterior rectal resection with total mesorectal excision is related to sexual and urinary disorders. Anastomotic leak and neo-adjuvant radiation therapy are effective factors in worsening pelvic function. We report a series of 50 elderly (age 70) patients who underwent laparoscopic total mesorectal excision inquired about pre and post-operative genito-urinary function. Patients were interviewed preoperatively, 1 and 9 months post-operatively with validated questionnaires about sexual and urinary function and quality of life. They also underwent urofluximetric test with ultrasound measurement of the bladder remnant volume. The geriatric assessment was performed with the BARTHEL index. Urinary and sexual function slightly worsened after surgery although not significantly. Mean Gastrointestinal Quality of Life Indicator score decreased significantly from pre operative levels at 1 month from surgery. BARTHEL index did not change significantly across surgery. Maximum urinary flow, mean urinary flow, bladder residual volume worsened after surgery although not significantly. Laparoscopic anterior rectal resection with total mesorectal excision affects the genito-urinary status of elderly patients. Incidence of severe dysfunctions is similar to normal aged population.
    MeSH term(s) Aged ; Aged, 80 and over ; Aging ; Erectile Dysfunction/etiology ; Female ; Humans ; Laparoscopy/adverse effects ; Laparoscopy/methods ; Male ; Prospective Studies ; Quality of Life ; Rectal Neoplasms/surgery ; Surveys and Questionnaires ; Treatment Outcome ; Urinary Incontinence/etiology
    Language English
    Publishing date 2016-07
    Publishing country Romania
    Document type Journal Article
    ZDB-ID 419244-8
    ISSN 1842-368X ; 1221-9118 ; 0009-4730 ; 0377-5003
    ISSN (online) 1842-368X
    ISSN 1221-9118 ; 0009-4730 ; 0377-5003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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