Artikel: Gestational Diabetes Mellitus Subtypes Classified by Oral Glucose Tolerance Test and Maternal and Perinatal Outcomes: Results of a Mexican Multicenter Prospective Cohort Study "Cuido Mi Embarazo".
Diabetes, metabolic syndrome and obesity : targets and therapy
2024 Band 17, Seite(n) 1491–1502
Abstract: Purpose: This study explores the impact of gestational diabetes mellitus (GDM) subtypes classified by oral glucose tolerance test (OGTT) values on maternal and perinatal outcomes.: Patients and methods: This multicenter prospective cohort study (May ... ...
| Abstract | Purpose: This study explores the impact of gestational diabetes mellitus (GDM) subtypes classified by oral glucose tolerance test (OGTT) values on maternal and perinatal outcomes. Patients and methods: This multicenter prospective cohort study (May 2019-December 2022) included participants from the Mexican multicenter cohort study Results: Of 2,056 Mexican pregnant women in the CME cohort, 294 (14.3%) had GDM; 53.7%, 34.4%, and 11.9% were classified as GDM-Sensitivity, GDM-Secretion, and GDM-Mixed subtypes, respectively. Women with GDM were older (p = 0.0001) and more often multiparous (p = 0.119) vs without GDM. Cesarean delivery (63.3%; p = 0.02) and neonate LGA (10.7%; p = 0.078) were higher in the GDM-Mixed group than the overall GDM group (55.6% and 8.4%, respectively). Pre-term birth was more common in the GDM-Sensitivity group than in the overall GDM group (10.2% vs 8.5%, respectively; p=0.022). At 6 months postpartum, prediabetes was more frequent in the GDM-Sensitivity group than in the overall GDM group (31.6% vs 25.5%). Type 2 diabetes was more common in the GDM-Mixed group than in the overall GDM group (10.0% vs 3.3%). Conclusion: GDM subtypes effectively stratified maternal and perinatal risks. GDM-Mixed subtype increased the risk of cesarean delivery, LGA, and type 2 diabetes postpartum. GDM subtypes may help personalize clinical interventions and optimize maternal and perinatal outcomes. |
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| Sprache | Englisch |
| Erscheinungsdatum | 2024-03-26 |
| Erscheinungsland | New Zealand |
| Dokumenttyp | Journal Article |
| ZDB-ID | 2494854-8 |
| ISSN | 1178-7007 |
| ISSN | 1178-7007 |
| DOI | 10.2147/DMSO.S450939 |
| Datenquelle | MEDical Literature Analysis and Retrieval System OnLINE |
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