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  1. AU="Gallagher, Timothy J"
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  4. AU="Carr, Kenneth D."
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  6. AU="Roberts, William Clifford"
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  1. Article: A Mirrored System of Health for the Uninsured: North Carolina's Independent Primary Care Safety Net.

    Jordan, Randolph S / Jones, Cynthia L / Gallagher, Timothy J

    North Carolina medical journal

    2020  Volume 81, Issue 2, Page(s) 141

    MeSH term(s) Health Services Accessibility ; Humans ; Medically Uninsured ; North Carolina ; Primary Health Care/organization & administration ; Safety-net Providers/organization & administration
    Language English
    Publishing date 2020-03-04
    Publishing country United States
    Document type Letter
    ZDB-ID 422795-5
    ISSN 0029-2559
    ISSN 0029-2559
    DOI 10.18043/ncm.81.2.141
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Integrating Allyl Electrophiles into Nickel-Catalyzed Conjunctive Cross-Coupling.

    Tran, Van T / Li, Zi-Qi / Gallagher, Timothy J / Derosa, Joseph / Liu, Peng / Engle, Keary M

    Angewandte Chemie (International ed. in English)

    2020  Volume 59, Issue 18, Page(s) 7029–7034

    Abstract: Allylation and conjunctive cross-coupling represent two useful, yet largely distinct, reactivity paradigms in catalysis. The union of these two processes would offer exciting possibilities in organic synthesis but remains largely unknown. Herein, we ... ...

    Abstract Allylation and conjunctive cross-coupling represent two useful, yet largely distinct, reactivity paradigms in catalysis. The union of these two processes would offer exciting possibilities in organic synthesis but remains largely unknown. Herein, we report the use of allyl electrophiles in nickel-catalyzed conjunctive cross-coupling with a non-conjugated alkene and dimethylzinc. The transformation is enabled by weakly coordinating, monodentate aza-heterocycle directing groups that are useful building blocks in synthesis, including saccharin, pyridones, pyrazoles, and triazoles. The reaction occurs under mild conditions and is compatible with a wide range of allyl electrophiles. High chemoselectivity through substrate directivity is demonstrated by the facile reactivity of the β-γ alkene of the starting material, whereas the ϵ-ζ alkene of the product is preserved. The generality of this approach is further illustrated through the development of an analogous method with alkyne substrates. Mechanistic studies reveal the importance of the dissociation of the weakly coordinating directing group to allow the allyl moiety to bind and facilitate C(sp
    MeSH term(s) Alkenes/chemistry ; Alkylation ; Allyl Compounds/chemistry ; Catalysis ; Molecular Structure ; Nickel/chemistry ; Organometallic Compounds/chemistry ; Pyrazoles/chemical synthesis ; Pyrazoles/chemistry ; Pyridones/chemical synthesis ; Pyridones/chemistry ; Saccharin/chemical synthesis ; Saccharin/chemistry ; Stereoisomerism ; Triazoles/chemical synthesis ; Triazoles/chemistry
    Chemical Substances Alkenes ; Allyl Compounds ; Organometallic Compounds ; Pyrazoles ; Pyridones ; Triazoles ; Nickel (7OV03QG267) ; Saccharin (FST467XS7D)
    Language English
    Publishing date 2020-03-13
    Publishing country Germany
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 2011836-3
    ISSN 1521-3773 ; 1433-7851
    ISSN (online) 1521-3773
    ISSN 1433-7851
    DOI 10.1002/anie.201915454
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Total Synthesis of Kibdelomycin.

    He, Chi / Wang, Yu / Bi, Cheng / Peters, David S / Gallagher, Timothy J / Teske, Johannes / Chen, Jason S / Corsetti, Rachel / D'Onofrio, Anthony / Lewis, Kim / Baran, Phil S

    Angewandte Chemie (International ed. in English)

    2022  Volume 61, Issue 32, Page(s) e202206183

    Abstract: A modular total synthesis of kibdelomycin is disclosed that should enable structure-activity relationship (SAR) studies of this interesting class of antibiotics. The route uses simple building blocks and addresses lingering questions about its structural ...

    Abstract A modular total synthesis of kibdelomycin is disclosed that should enable structure-activity relationship (SAR) studies of this interesting class of antibiotics. The route uses simple building blocks and addresses lingering questions about its structural assignment and relationship to amycolamicin, a recently described natural product reported to have a similar structure. Initial antibacterial assays reveal that both C-22 epimers (the N-glycosidic linkage) of the natural product have similar activity while structurally truncated analogs lose activity.
    MeSH term(s) Anti-Bacterial Agents/chemistry ; Biological Products ; Pyrroles ; Pyrrolidinones/chemistry ; Structure-Activity Relationship
    Chemical Substances Anti-Bacterial Agents ; Biological Products ; Pyrroles ; Pyrrolidinones ; kibdelomycin
    Language English
    Publishing date 2022-07-06
    Publishing country Germany
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, N.I.H., Extramural
    ZDB-ID 2011836-3
    ISSN 1521-3773 ; 1433-7851
    ISSN (online) 1521-3773
    ISSN 1433-7851
    DOI 10.1002/anie.202206183
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Further analysis of a doctor-patient nonverbal communication instrument.

    Gallagher, Timothy J / Hartung, Paul J / Gerzina, Holly / Gregory, Stanford W / Merolla, Dave

    Patient education and counseling

    2005  Volume 57, Issue 3, Page(s) 262–271

    Abstract: This study examines the reliability and validity of the relational communication scale for observational measurement (RCS-O) using a random sample of 80 videotaped interactions of medical students interviewing standardized patients (SPs). The RCS-O is a ... ...

    Abstract This study examines the reliability and validity of the relational communication scale for observational measurement (RCS-O) using a random sample of 80 videotaped interactions of medical students interviewing standardized patients (SPs). The RCS-O is a 34-item instrument designed to measure the nonverbal communication of physicians interacting with patients. The instrument was applied and examined in two different interview scenarios. In the first scenario (year 1), the medical student's interview objective is to demonstrate patient-centered interviewing skills as the SP presents with a psychosocial concern. In the second scenario (year 3), the student's interview objective is to demonstrate both doctor-centered and patient-centered skills as the SP presents with a case common in primary care. In the year 1 scenario, 19 of the 34 RCS-O items met acceptable levels of inter-rater agreement and reliability. In the year 3 scenario, 26 items met acceptable levels of inter-rater agreement and reliability. Factor analysis indicated that in both scenarios each of the four primary relational communication dimensions was salient: intimacy, composure, formality, and dominance. Measures of correlation and differences involving the RCS-O dimensions and structural features of the interviews (e.g., number of questions asked by the medical student) are examined.
    MeSH term(s) Affect ; Clinical Competence/standards ; Cues ; Educational Measurement/methods ; Factor Analysis, Statistical ; Female ; Humans ; Interviews as Topic/methods ; Male ; Medical History Taking/methods ; Models, Psychological ; Nonverbal Communication/psychology ; Observation/methods ; Observer Variation ; Patient Participation/psychology ; Patient Simulation ; Patient-Centered Care ; Physician-Patient Relations ; Power (Psychology) ; Social Distance ; Social Dominance ; Students, Medical/psychology ; Trust ; Videotape Recording/methods
    Language English
    Publishing date 2005-06
    Publishing country Ireland
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Validation Studies
    ZDB-ID 605590-4
    ISSN 1873-5134 ; 0738-3991
    ISSN (online) 1873-5134
    ISSN 0738-3991
    DOI 10.1016/j.pec.2004.06.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book: Housing assets and savings behaviour among the elderly in Great Britain

    Disney, Richard / Gallagher, Timothy J / Henley, Andrew

    (Working paper series / Institute for Fiscal Studies ; 95,22)

    1995  

    Author's details Richard Disney ; Timothy Gallagher ; Andrew Henley
    Series title Working paper series / Institute for Fiscal Studies ; 95,22
    Keywords Grundeigentum ; Sparen ; Lebenszyklus ; Altersgruppe ; Theorie ; Schätzung ; Großbritannien ; 12*21 ; 15*25*35*45
    Language English
    Size 26 S., graph. Darst.
    Document type Book
    Database ECONomics Information System

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  6. Book: Housing costs and the behaviour of elderly households

    Disney, Richard / Gallagher, Timothy J / Henley, Andrew

    (Studies in economics ; 94,8)

    1994  

    Author's details Richard Disney, Timothy Gallagher and Andrew Henley
    Series title Studies in economics ; 94,8
    Keywords 24;34;60
    Language English
    Size 46 S., graph. Darst.
    Document type Book
    Database ECONomics Information System

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  7. Article: The use of interest rate futures and options by corporate financial managers

    Block, Stanley B / Gallagher, Timothy J

    Financial management 15 ,3, S. 73-78

    1986  

    Author's details Stanley B. Block and Timothy J. Gallagher
    Keywords Zinsderivat ; Betriebliche Finanzwirtschaft ; USA
    Language English
    Publisher Wiley-Blackwell
    Publishing place Malden, Mass. [u.a.]
    Document type Article
    ZDB-ID 186034-3 ; 2254144-5
    ISSN 1755-053X ; 0046-3892
    ISSN (online) 1755-053X
    ISSN 0046-3892
    Database ECONomics Information System

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