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Article ; Online: Efecto de un entrenamiento con ejercicios de autocarga a alta velocidad en el equilibrio dinámico y estático en mujeres adultas mayores.

Jaque-Gallardo, Cristian / Véliz-Campillay, Phillip / Cancino-López, Jorge

2021 Volume 147, Issue 9, Page(s) 1136–1143

Abstract: Background: High-speed resistance training programs aiming to increase muscle power have beneficial effects on balance.: Aim: To compare the effect of high-speed bodyweight resistance training and normal-speed bodyweight resistance training on the ... ...

Title translation	Effect of a high-speed bodyweight resistance training on timed up and go and one leg stance in older women.
Abstract	Background: High-speed resistance training programs aiming to increase muscle power have beneficial effects on balance. Aim: To compare the effect of high-speed bodyweight resistance training and normal-speed bodyweight resistance training on the static and dynamic balance in community-dwelling older women. Material and methods: Thirty-five non-disabled community-dwelling women aged 65 to 80 years were trained for 12 weeks using a high-speed bodyweight resistance training (HS-BT) or a normal-speed bodyweight resistance training (NS-BT). At baseline and after the intervention, One Leg Stance (OLS) and Timed Up and Go (TUG) tests were measured. Participants with an attendance to training sessions of less than 70% were excluded from the final analysis. Results: Data from 26 participants were analyzed, 14 women aged 71 ± 4 years who received HS-BT and 12 women aged 73 ± 4 years who received NS-BT. After 12 weeks of training, a significant improvement in TUG was observed in women receiving HS-BT (ΔTUG -1.07 sec, p < 0.01), but without changes in the OLS test. No significant changes were observed in any of the tests in the NS-BT group. Conclusions: High-speed bodyweight resistance training for 12 weeks improved TUG in these women.
MeSH term(s)	Aged ; Aged, 80 and over ; Female ; Humans ; Leg ; Resistance Training
Language	Spanish
Publishing date	2021-02-24
Publishing country	Chile
Document type	Journal Article
ZDB-ID	732136-3
ISSN	0717-6163 ; 0034-9887
ISSN (online)	0717-6163
ISSN	0034-9887
DOI	10.4067/s0034-98872019000901136
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Article ; Online: Phenotypic characterization of liver tissue heterogeneity through a next-generation 3D single-cell atlas.

Martínez-Torres, Dilan / Maldonado, Valentina / Pérez-Gallardo, Cristian / Yañez, Rodrigo / Candia, Valeria / Kalaidzidis, Yannis / Zerial, Marino / Morales-Navarrete, Hernán / Segovia-Miranda, Fabián

Scientific reports

2024 Volume 14, Issue 1, Page(s) 2823

Abstract: Three-dimensional (3D) geometrical models are potent tools for quantifying complex tissue features and exploring structure-function relationships. However, these models are generally incomplete due to experimental limitations in acquiring multiple (> 4) ... ...

Abstract	Three-dimensional (3D) geometrical models are potent tools for quantifying complex tissue features and exploring structure-function relationships. However, these models are generally incomplete due to experimental limitations in acquiring multiple (> 4) fluorescent channels in thick tissue sections simultaneously. Indeed, predictive geometrical and functional models of the liver have been restricted to few tissue and cellular components, excluding important cellular populations such as hepatic stellate cells (HSCs) and Kupffer cells (KCs). Here, we combined deep-tissue immunostaining, multiphoton microscopy, deep-learning techniques, and 3D image processing to computationally expand the number of simultaneously reconstructed tissue structures. We then generated a spatial single-cell atlas of hepatic architecture (Hep3D), including all main tissue and cellular components at different stages of post-natal development in mice. We used Hep3D to quantitatively study 1) hepatic morphodynamics from early post-natal development to adulthood, and 2) the effect on the liver's overall structure when changing the hepatic environment after removing KCs. In addition to a complete description of bile canaliculi and sinusoidal network remodeling, our analysis uncovered unexpected spatiotemporal patterns of non-parenchymal cells and hepatocytes differing in size, number of nuclei, and DNA content. Surprisingly, we found that the specific depletion of KCs results in morphological changes in hepatocytes and HSCs. These findings reveal novel characteristics of liver heterogeneity and have important implications for both the structural organization of liver tissue and its function. Our next-gen 3D single-cell atlas is a powerful tool to understand liver tissue architecture, opening up avenues for in-depth investigations into tissue structure across both normal and pathological conditions.
MeSH term(s)	Mice ; Animals ; Liver/pathology ; Hepatocytes ; Kupffer Cells/pathology ; Hepatic Stellate Cells/pathology ; Bile Canaliculi
Language	English
Publishing date	2024-02-03
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-024-53309-4
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Article ; Online: A narrative on diversity, equity, and inclusion in surgery: insights from the European Society of Coloproctology and identification of points for action.

Garoufalia, Zoe / Bellato, Vittoria / Cunha, Miguel F / Avellaneda, Nicolas / Dudi-Venkata, Nagendra N / Gallardo, Cristián / Meyer, Jeremy / Zaffaroni, Gloria / Christensen, Peter / Aytac, Erman / Brady, Richard R W / Pellino, Gianluca

Updates in surgery

2024 Volume 76, Issue 2, Page(s) 529–537

Abstract: The focus of the 2022 European Society of Coloproctology (ESCP) annual campaign was diversity, equity, and inclusion (DEI) in surgery. The ESCP "Operation Equal Access" campaign sought to interview key-opinion leaders and trainees, to raise awareness on ... ...

Abstract	The focus of the 2022 European Society of Coloproctology (ESCP) annual campaign was diversity, equity, and inclusion (DEI) in surgery. The ESCP "Operation Equal Access" campaign sought to interview key-opinion leaders and trainees, to raise awareness on inequalities, inform the community of the status of the topic, and to identify future areas for improvement. The ESCP Social Media Working Group interviewed experts who have made significant contributions to DEI in colorectal surgery and were acknowledged opinion leaders in the field. The interviews focused on their career, professional life, experiences, and opportunities during their training, and their views on DEI in colorectal surgery. DEI principles, education, and values need further promotion to reduce and address bias within the profession and overall improve the experience of minority community including health professionals and patients. International Societies are working to facilitate training opportunities and overcome DEI, and networking have contributed to that. Collaborations between societies will be pivotal to contribute to offering research and leadership opportunities equally. Access to advanced workshops including cadaveric training and simulation can be consistently promoted and provided globally via societies through telemonitoring. Involving patients in research should be encouraged, as it brings the perspective of a living experience.
MeSH term(s)	Humans ; Diversity, Equity, Inclusion ; Colorectal Surgery ; Computer Simulation ; Social Media
Language	English
Publishing date	2024-01-27
Publishing country	Italy
Document type	Journal Article
ZDB-ID	2572692-4
ISSN	2038-3312 ; 2038-131X
ISSN (online)	2038-3312
ISSN	2038-131X
DOI	10.1007/s13304-023-01685-3
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Article ; Online: Report from 'Virtually Vilnius': the 15th Scientific and Annual Conference of the European Society of Coloproctology, 21-23 September 2020.

Pellino, Gianluca / Bellato, Vittoria / Cunha, Miguel / Gallardo, Cristián / Garoufalia, Zoe / Gujjuri, Rohan / Zaffaroni, Gloria / Brady, Richard R W

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

2021 Volume 23, Issue 7, Page(s) 1658–1661

MeSH term(s)	Colonic Diseases ; Humans ; Rectal Diseases
Language	English
Publishing date	2021-07-14
Publishing country	England
Document type	Journal Article
ZDB-ID	1440017-0
ISSN	1463-1318 ; 1462-8910
ISSN (online)	1463-1318
ISSN	1462-8910
DOI	10.1111/codi.15632
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Article ; Online: Report from 'ESCP 2021 Virtual': the 16th Scientific and Annual Conference of the European Society of Coloproctology, 22-24 September 2021.

Cunha, Miguel / Garoufalia, Zoe / Bellato, Vittoria / An, Yongbo / Dudi-Venkata, Nagendra N / Gallardo, Cristián / Zaffaroni, Gloria / Aytac, Erman / Brady, Richard R W / Pellino, Gianluca

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

2022 Volume 24, Issue 5, Page(s) 652–656

MeSH term(s)	Colonic Diseases ; Humans ; Rectal Diseases
Language	English
Publishing date	2022-02-07
Publishing country	England
Document type	Journal Article
ZDB-ID	1440017-0
ISSN	1463-1318 ; 1462-8910
ISSN (online)	1463-1318
ISSN	1462-8910
DOI	10.1111/codi.16061
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Article ; Online: Obesity and physical activity patterns in children and adolescents.

Laguna, María / Ruiz, Jonatan R / Gallardo, Cristian / García-Pastor, Teresa / Lara, María-Teresa / Aznar, Susana

Journal of paediatrics and child health

2013 Volume 49, Issue 11, Page(s) 942–949

Abstract: Aim: The aim of this study is to measure objectively and accurately the physical activity (PA) patterns in Spanish children and adolescents according to their obesity status, gender and age groups.: Methods: A sample of 487 children and 274 ... ...

Abstract	Aim: The aim of this study is to measure objectively and accurately the physical activity (PA) patterns in Spanish children and adolescents according to their obesity status, gender and age groups. Methods: A sample of 487 children and 274 adolescents from the European Youth Heart Study participated in the study. The variables measured were anthropometric characteristics (height, weight and body mass index), and PA was measured during 6 consecutive days using the GT1M accelerometer. Results: Three-way analysis of variance (age × gender × obesity status) showed significant differences in the interaction effect in age, gender and obesity status (normal-weight and overweight/obesity) for mean of moderate-to-vigorous PA (MVPA) (P = 0.02) and vigorous PA (VPA) (P = 0.014) within the sample. Nine-year-old normal-weight children achieved significantly (P < 0.05) more MVPA on weekdays than 9-year-old overweight/obesity children. During weekend days, all sample achieved significant more MVPA (P < 0.01) and significant more VPA (P < 0.05) than during weekdays. Few children (37.5% of 9-year-old normal-weight and 34.0% of 9-year-old overweight/obese) and adolescents (16.4% and 27.3% normal-weight and overweight/obese, respectively) met the current health-related recommendations of 60 min of MVPA daily. Conclusions: It is clear that activity levels are insufficient for all children, in particular overweight/obese children and adolescents, although the precise nature of the relationship appears to differ between boys and girls.
MeSH term(s)	Accelerometry ; Adolescent ; Age Factors ; Anthropometry ; Child ; Cross-Sectional Studies ; Female ; Humans ; Male ; Motor Activity ; Obesity/epidemiology ; Sex Distribution ; Spain/epidemiology
Language	English
Publishing date	2013-11
Publishing country	Australia
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1024476-1
ISSN	1440-1754 ; 1034-4810
ISSN (online)	1440-1754
ISSN	1034-4810
DOI	10.1111/jpc.12442
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Article ; Online: Levels of moderate--vigorous physical activity are low in Spanish children with cystic fibrosis: a comparison with healthy controls.

Aznar, Susana / Gallardo, Cristian / Fiuza-Luces, Carmen / Santana-Sosa, Elena / López-Mojares, Luis M / Santalla, Alfredo / Rodríguez-Romo, Gabriel / Pérez, Margarita / Garatachea, Nuria / Lucia, Alejandro

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society

2014 Volume 13, Issue 3, Page(s) 335–340

Abstract: Background: Physical activity (PA) is recommended as part of the treatment regimen for cystic fibrosis (CF) although objective methods have been scarcely used to monitor achievement of PA guidelines.: Methods: PA was measured by accelerometer in ... ...

Abstract	Background: Physical activity (PA) is recommended as part of the treatment regimen for cystic fibrosis (CF) although objective methods have been scarcely used to monitor achievement of PA guidelines. Methods: PA was measured by accelerometer in outpatient CF children (n=47) and results were compared with those obtained in age- and gender-matched healthy controls (n=39). Results: 2.1% of the outpatients fulfilled PA guidelines (i.e. ≥60min·day(-1) of moderate-to-vigorous PA (MVPA)) vs. 34.2% of controls. Overall, lower MVPA levels were observed in CF patients than controls despite the former undergoing more light or total PA. Peak oxygen uptake was also lower in the CF group than in controls (37.5±7.8 vs. 43.5±7.6ml·kg(-1)·min(-1), p=0.002) and was correlated with MVPA and vigorous PA in the former. Conclusions: These findings support a need to promote PA interventions (including MVPA) targeted at improving cardiorespiratory fitness in CF children.
MeSH term(s)	Accelerometry ; Adolescent ; Child ; Cystic Fibrosis/physiopathology ; Exercise/physiology ; Female ; Humans ; Male ; Motor Activity/physiology ; Oxygen Consumption/physiology ; Physical Fitness/physiology ; Spain
Language	English
Publishing date	2014-05
Publishing country	Netherlands
Document type	Comparative Study ; Journal Article
ZDB-ID	2091075-7
ISSN	1873-5010 ; 1569-1993
ISSN (online)	1873-5010
ISSN	1569-1993
DOI	10.1016/j.jcf.2013.10.004
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Article ; Online: Health-related quality of life of Spanish children with cystic fibrosis.

Groeneveld, Iris F / Sosa, Elena S / Pérez, Margarita / Fiuza-Luces, Carmen / Gonzalez-Saiz, Laura / Gallardo, Cristian / López-Mojares, Luis M / Ruiz, Jonatan R / Lucia, Alejandro

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

2012 Volume 21, Issue 10, Page(s) 1837–1845

Abstract: Purpose: To investigate (1) the contributions of sex, age, nutritional status- and physical-fitness-related variables on health-related quality of life (HRQOL) in Spanish children with cystic fibrosis, and (2) the agreement on HRQOL between children and ...

Abstract	Purpose: To investigate (1) the contributions of sex, age, nutritional status- and physical-fitness-related variables on health-related quality of life (HRQOL) in Spanish children with cystic fibrosis, and (2) the agreement on HRQOL between children and their parents. Methods: In 28 children aged 6-17 years, body mass index percentile, percentage body fat, physical activity, pulmonary function, cardiorespiratory fitness, functional mobility, and dynamic muscle strength were determined using objective measures. HRQOL was measured using the revised version of the cystic fibrosis questionnaire. Simple and multiple linear regression analyses were performed to determine the variables associated with HRQOL. To assess the agreement on HRQOL between children and parents, intra-class correlation coefficients (ICCs) were calculated. Results: Girls reported worse emotional functioning, a higher treatment burden, and more respiratory problems than boys. Greater functional mobility appeared associated with a less favourable body image and more eating disturbances. Agreement on HRQOL between children and parents was good to excellent, except for the domain of treatment burden. Conclusions: Sex and age were stronger predictors of HRQOL than nutritional status- or physical-fitness-related variables. Children reported a lower treatment burden than their parents perceived them to have.
MeSH term(s)	Adolescent ; Body Mass Index ; Child ; Cystic Fibrosis/complications ; Cystic Fibrosis/physiopathology ; Cystic Fibrosis/psychology ; Female ; Health Status ; Humans ; Male ; Nutritional Status ; Parents ; Physical Fitness ; Quality of Life ; Spain ; Surveys and Questionnaires
Language	English
Publishing date	2012-01-05
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1161148-0
ISSN	1573-2649 ; 0962-9343
ISSN (online)	1573-2649
ISSN	0962-9343
DOI	10.1007/s11136-011-0100-8
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Article ; Online: Health enhancing strength training in nonagenarians (STRONG)

Sanz Natalia / Santamaría Victor / Sanz Nekane / Sanz Ibáñez Maria J / Gil Pedro / Villarán Margarita / Bustamante-Ara Natalia / Ruiz Jonatan R / Rexach José / Prada Ana / Gallardo Cristian / Romo Gabriel / Lucia Alejandro

BMC Public Health, Vol 9, Iss 1, p

rationale, design and methods

2009 Volume 152

Abstract: Abstract Background The Health Enhancing Strength Training in Nonagenarians (STRONG) is a randomised control trial to assess the effectiveness of an aerobic and strength training program for improving muscle strength, functional capacity and quality of ... ...

Abstract	Abstract Background The Health Enhancing Strength Training in Nonagenarians (STRONG) is a randomised control trial to assess the effectiveness of an aerobic and strength training program for improving muscle strength, functional capacity and quality of life in nonagenarians. Methods Sixty (51 women) nonagenarians (age range: 90–102 years) who live in a geriatric nursing home will be randomly assigned to either a usual care (control) group (n = 30) or an intervention (training) group (n = 30). Participants allocated in the usual care group will receive general physical activity guidelines and participants allocated in the intervention group will also enrol in three weekly non-consecutive individualized training sessions (~45–50 min each) during 8 weeks. The exercise program will consist of muscular strength [with a special focus on leg press at 30% (start of the program) to 70% 1 repetition maximum (end)] and aerobic exercises (cycle-ergometry during 3–5 to 15 minutes at 12–14 points in the rate of perceived exertion scale). Results Results from STRONG will help to better understand the potential of regular physical activity for improving the well-being of the oldest population groups. Conclusion The increase in life expectancy together with the dramatic decrease in birth rates in industrialized countries calls the attention to health care systems and public health policymakers to focus attention on promoting healthy lifestyle in the highest sector of the population pyramid. Our study attempts to improve functional capacity and QOL of nonagenarians by implementing an individualised aerobic and strength training program in a geriatric residential care. Results from STRONG will help to better understand the potential of regular physical activity for improving the well being even in persons aged 90 years or over. Trail Registration ClinicalTrials.gov ID: NCT00848978
Keywords	Public aspects of medicine ; RA1-1270
Subject code	796
Language	English
Publishing date	2009-05-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
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Article ; Online: Short-term, light- to moderate-intensity exercise training improves leg muscle strength in the oldest old: a randomized controlled trial.

Serra-Rexach, José A / Bustamante-Ara, Natalia / Hierro Villarán, Margarita / González Gil, Pedro / Sanz Ibáñez, Maria J / Blanco Sanz, Nekane / Ortega Santamaría, Victor / Gutiérrez Sanz, Natalia / Marín Prada, Ana B / Gallardo, Cristian / Rodríguez Romo, Gabriel / Ruiz, Jonatan R / Lucia, Alejandro

Journal of the American Geriatrics Society

2011 Volume 59, Issue 4, Page(s) 594–602

MeSH term(s)	Aged, 80 and over ; Aging/physiology ; Exercise Tolerance/physiology ; Female ; Follow-Up Studies ; Humans ; Leg/physiology ; Male ; Muscle Strength/physiology ; Muscle Stretching Exercises/methods ; Retrospective Studies
Language	English
Publishing date	2011-04
Publishing country	United States
Document type	Comparative Study ; Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
ZDB-ID	80363-7
ISSN	1532-5415 ; 0002-8614
ISSN (online)	1532-5415
ISSN	0002-8614
DOI	10.1111/j.1532-5415.2011.03356.x
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