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  1. Article ; Online: Occurrence of Microplastics in Tap and Bottled Water: Current Knowledge.

    Gambino, Isabella / Bagordo, Francesco / Grassi, Tiziana / Panico, Alessandra / De Donno, Antonella

    International journal of environmental research and public health

    2022  Volume 19, Issue 9

    Abstract: A narrative review was carried out to describe the current knowledge related to the occurrence of MPs in drinking water. The reviewed studies ( ...

    Abstract A narrative review was carried out to describe the current knowledge related to the occurrence of MPs in drinking water. The reviewed studies (
    MeSH term(s) Drinking Water ; Environmental Monitoring ; Humans ; Microplastics/toxicity ; Plastics ; Water Pollutants, Chemical/analysis
    Chemical Substances Drinking Water ; Microplastics ; Plastics ; Water Pollutants, Chemical
    Language English
    Publishing date 2022-04-26
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph19095283
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Modelling micropollutant cycle in Lake Como in a winter scenario: Implications for water use and reuse, ecosystem services, and the EU zero pollution action plan.

    Di Guardo, Antonio / Castiglioni, Sara / Gambino, Isabella / Sailis, Alessia / Salmoiraghi, Giulia / Schiarea, Silvia / Vighi, Marco / Terzaghi, Elisa

    The Science of the total environment

    2023  Volume 906, Page(s) 167594

    Abstract: The fate and effects of 42 pharmaceuticals was studied in Lake Como (Italy), in wastewater treatment plants delivering water to the lake, in two rivers and in potable water obtained from lake water. Lake Como is one of the deepest and largest lakes in ... ...

    Abstract The fate and effects of 42 pharmaceuticals was studied in Lake Como (Italy), in wastewater treatment plants delivering water to the lake, in two rivers and in potable water obtained from lake water. Lake Como is one of the deepest and largest lakes in Northern Italy, serving important ecosystem services (i.e., drinking water, recreational, industrial, irrigation uses), some of which are currently at risk giving the current water scarcity and climate change scenarios. The highest concentrations measured in lake water were those of diclofenac, followed by carbamazepine, its metabolite, and clarithromycin. The data measured allowed to calibrate and run a fugacity-based lake model, which showed that the most important chemical load generally comes from the advective water from the north of the lake, rather than from the direct wastewater treatment plant (WWTP) discharges. This indicates that only an important reduction of chemical discharge (reduced use or extensive treatment) at a drainage basin level could significantly reduce concentrations in water. This has strong implications on how to implement the EU zero pollution action plan to significantly improve water ecosystem and human health protection.
    MeSH term(s) Humans ; Lakes ; Ecosystem ; Water ; Water Pollutants, Chemical/analysis ; Wastewater ; Environmental Monitoring
    Chemical Substances Water (059QF0KO0R) ; Water Pollutants, Chemical ; Wastewater
    Language English
    Publishing date 2023-10-05
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2023.167594
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 949: Show issues Location:
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  3. Article ; Online: Buccal micronucleus cytome assay in children living in an area with low anthropogenic pressure: The EFFE.BI.P. study.

    Bagordo, Francesco / Panico, Alessandra / Zizza, Antonella / Serio, Francesca / Idolo, Adele / Tumolo, Maria Rosaria / Guido, Marcello / Gambino, Isabella / Grassi, Tiziana

    Mutation research. Genetic toxicology and environmental mutagenesis

    2021  Volume 873, Page(s) 503424

    Abstract: The study aimed to evaluate the micronucleus (MN) frequency in exfoliated buccal cells (EBCs) of 256 6-8-years-old schoolchildren living in a rural area of Salento peninsula (Southern Italy) with low anthropogenic pressure and with a normal rate of ... ...

    Abstract The study aimed to evaluate the micronucleus (MN) frequency in exfoliated buccal cells (EBCs) of 256 6-8-years-old schoolchildren living in a rural area of Salento peninsula (Southern Italy) with low anthropogenic pressure and with a normal rate of chronic diseases in order to determine the basal level of MN and identify which factors are able to influence it. Information about the personal data, lifestyles and dietary habits of the children were obtained by the administration of a questionnaire to their parents. The buccal micronucleus cytome assay was performed to evaluate the presence of early genotoxic effects among the children. In addition, the level of environmental exposure was assessed by sampling atmospheric particulate fractions near the schools attended by participants. The association between MN frequency and individual or environmental factors was also assessed. The children had a mean MN frequency of 0.27 ± 0.43‰ (95%CI = 0.22-0.33). This frequency was positively associated with vehicular traffic (OR = 2.99; 95%CI = 1.15-7.74) and negatively associated with a high educational level of the mother (OR = 0.41; 95%CI = 0.18-0.95) and physical exercise (OR = 0.56; 95%CI = 0.32-0.57). Data on genotoxic effects in buccal cells found in this study could be considered as the MN level in a pediatric population not exposed to environmental pollution.
    MeSH term(s) Anthropogenic Effects ; Child ; DNA Damage ; Environmental Exposure/adverse effects ; Humans ; Italy ; Micronucleus Tests ; Mouth Mucosa
    Language English
    Publishing date 2021-11-05
    Publishing country Netherlands
    Document type Journal Article
    ISSN 1879-3592
    ISSN (online) 1879-3592
    DOI 10.1016/j.mrgentox.2021.503424
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  4. Article ; Online: Direct detection of free vitamin D as a tool to assess risk conditions associated with chronic plaque psoriasis.

    Grassi, Tiziana / Panico, Alessandra / Bagordo, Francesco / Imbriani, Giovanni / Gambino, Isabella / Lobreglio, Debora / Lobreglio, Giambattista / Congedo, Maurizio / DE Donno, Antonella

    Journal of preventive medicine and hygiene

    2020  Volume 61, Issue 3, Page(s) E489–E495

    Abstract: Introduction: Psoriasis is a major public health problem that results in high social and health costs. New approaches and methods are required to identify any conditions related to the disease and comorbidity development. The vitamin D deficiency is ... ...

    Abstract Introduction: Psoriasis is a major public health problem that results in high social and health costs. New approaches and methods are required to identify any conditions related to the disease and comorbidity development. The vitamin D deficiency is associated to psoriasis and could play an important role in its pathogenesis. However, the serum level of vitamin D is currently measured as total vitamin D, which is affected by wide variability. Therefore, the determination of the free form could be more significant, since it is independent of confounding factors. A cross-sectional study was performed to assess the association between chronic plaque psoriasis and serum level of free vitamin D, detected by a direct analytical method.
    Methods: The levels of bioavailable vitamin D, total vitamin D and other metabolic parameters whose homeostasis is regulated by vitamin D were evaluated in 72 psoriasis patients and in 48 healthy controls. A direct immunoassay method was used to measure serum free vitamin D level. Analysis of covariance was performed to calculate estimated marginal means (EMM) and 95% confidence interval (CI), after adjustment for age, sex and BMI, within the two groups.
    Results: Patients showed an EMM of 5.526 ± 0.271pg/ml, 95% CI 4.989-6.063; while controls an EMM of 6.776 ± 0.271 pg/ml, 95% CI 6.115-7.437.
    Conclusions: Chronic plaque psoriasis patients exhibited a serum level of free vitamin D lower than controls. The direct immunoassay method could represent a useful tool to assess vitamin D status and identify a risk condition associated with the onset of the pathology.
    MeSH term(s) Adult ; Cross-Sectional Studies ; Female ; Humans ; Male ; Middle Aged ; Psoriasis/diagnosis ; Vitamin D/blood
    Chemical Substances Vitamin D (1406-16-2)
    Language English
    Publishing date 2020-10-06
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 1102926-2
    ISSN 2421-4248 ; 1121-2233
    ISSN (online) 2421-4248
    ISSN 1121-2233
    DOI 10.15167/2421-4248/jpmh2020.61.3.1482
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 990: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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