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  1. Article ; Online: Tackling gliomas with nanoformulated antineoplastic drugs: suitability of hyaluronic acid nanoparticles.

    Ganau, M

    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico

    2013  Volume 16, Issue 2, Page(s) 220–223

    MeSH term(s) Antineoplastic Agents/administration & dosage ; Antineoplastic Agents/pharmacokinetics ; Brain Neoplasms/drug therapy ; Brain Neoplasms/metabolism ; Chemistry, Pharmaceutical/methods ; Drug Carriers/pharmacokinetics ; Drug Carriers/therapeutic use ; Drug Stability ; Glioma/drug therapy ; Glioma/metabolism ; Humans ; Hyaluronic Acid/chemistry ; Hyaluronic Acid/pharmacokinetics ; Nanoparticles/chemistry ; Nanoparticles/metabolism ; Nanoparticles/therapeutic use
    Chemical Substances Antineoplastic Agents ; Drug Carriers ; Hyaluronic Acid (9004-61-9)
    Language English
    Publishing date 2013-09-27
    Publishing country Italy
    Document type Letter
    ZDB-ID 2397359-6
    ISSN 1699-3055 ; 1699-048X
    ISSN (online) 1699-3055
    ISSN 1699-048X
    DOI 10.1007/s12094-013-1114-1
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    Zs.A 6644: Show issues Location:
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  2. Article ; Online: Considerations regarding FACE-Q® craniofacial as a newly developed QoL-PROMs questionnaire suitable for paediatric and adult cranioplasty patients.

    Ganau, Mario / Calisto, Amedeo / Thomas, Gregory P L

    Neurosurgical review

    2023  Volume 46, Issue 1, Page(s) 141

    MeSH term(s) Humans ; Child ; Adult ; Quality of Life ; Skull/surgery ; Surveys and Questionnaires
    Language English
    Publishing date 2023-06-19
    Publishing country Germany
    Document type Letter ; Comment
    ZDB-ID 6907-3
    ISSN 1437-2320 ; 0344-5607
    ISSN (online) 1437-2320
    ISSN 0344-5607
    DOI 10.1007/s10143-023-02054-9
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    Zs.A 1445: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  3. Article ; Online: Aggressive primary scalp lymphoma mimicking an acute epidural hematoma: Case report and review of the literature.

    Thibault, C / Chibbaro, S / Ganau, M / Nicolae, A / Todeschi, J / Mallereau, C-H

    Neuro-Chirurgie

    2022  Volume 68, Issue 5, Page(s) e34–e39

    Abstract: Background: Cutaneous Central Follicular Lymphoma (CCFL) is a type B cutaneous lymphoma with a usually indolent course. Scalp localization of CCFL is extremely rare, we report a new case mimicking an epidural hematoma, and showing a rapid progression ... ...

    Abstract Background: Cutaneous Central Follicular Lymphoma (CCFL) is a type B cutaneous lymphoma with a usually indolent course. Scalp localization of CCFL is extremely rare, we report a new case mimicking an epidural hematoma, and showing a rapid progression with aggressive infiltration of skin, calvaria, dura and brain parenchyma.
    Case report: A 58-year-old patient with an unlabeled polymalformative syndrome was admitted to the Emergency department following a head injury secondary to a self-resolving tonic-clonic epileptic seizure. The initial CT-scan was interpreted as a minor subcutaneous and epidural hematoma initially deemed for conservative management. Within 4 days, the patient showed a progressive neurological deterioration culminating into a stuporous status which prompted a constrast-enhanced brain MRI. The scan revealed a multilayered solid lesion, extending from the subgaleal compartment to the subdural space, threatening the integrity of overlying skin and causing infiltration of the brain parenchyma. Following emergency neurosurgical excision a definitive histology diagnosis of central follicular lymphoma was made. A focused chemotherapy with high-dose Methotrexate with R-CHOP protocol led to disease control until the latest follow up at 2 years.
    Conclusion: To our knowledge, this case represents the first CCFL invading the brain parenchyma and the second extending to the dura. Although such tumor is usually indolent the aggressive behavior herein reported extend the differential diagnosis to high-grade meningiomas, sarcomas, and metastases. Prognostication and appropriate adjuvant treatment require prompt surgical excision and histological confirmation.
    MeSH term(s) Hematoma, Epidural, Cranial/diagnosis ; Hematoma, Epidural, Cranial/etiology ; Hematoma, Epidural, Cranial/surgery ; Humans ; Lymphoma, Follicular/complications ; Methotrexate ; Middle Aged ; Scalp ; Tomography, X-Ray Computed/adverse effects
    Chemical Substances Methotrexate (YL5FZ2Y5U1)
    Language English
    Publishing date 2022-04-25
    Publishing country France
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 207146-0
    ISSN 1773-0619 ; 0028-3770 ; 0150-9586
    ISSN (online) 1773-0619
    ISSN 0028-3770 ; 0150-9586
    DOI 10.1016/j.neuchi.2022.03.005
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  4. Article ; Online: Editorial: From simulation to the operating theatre: new insights in translational surgery.

    Balak, Naci / Tsianaka, Eleni / Zoia, Cesare / Sekhar, Amitendu / Ganau, Mario

    Frontiers in medical technology

    2023  Volume 5, Page(s) 1282248

    Language English
    Publishing date 2023-09-21
    Publishing country Switzerland
    Document type Editorial
    ISSN 2673-3129
    ISSN (online) 2673-3129
    DOI 10.3389/fmedt.2023.1282248
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  5. Article ; Online: Seeking a fine balance between effective antithrombotic prophylaxis and safety drug profile in the elderly population: the special case of traumatic brain injury.

    Ganau, Laura / Syrmos, Nikolaos / Ligarotti, Gianfranco K I / Ganau, Mario

    Acta neurochirurgica

    2023  Volume 165, Issue 8, Page(s) 2215–2218

    MeSH term(s) Humans ; Aged ; Fibrinolytic Agents/adverse effects ; Brain Injuries, Traumatic/drug therapy ; Brain Injuries
    Chemical Substances Fibrinolytic Agents
    Language English
    Publishing date 2023-07-07
    Publishing country Austria
    Document type Letter
    ZDB-ID 80010-7
    ISSN 0942-0940 ; 0001-6268
    ISSN (online) 0942-0940
    ISSN 0001-6268
    DOI 10.1007/s00701-023-05699-z
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  6. Article: Traumatic Brain Injuries: Comprehensive Management of Complex Clinical Scenarios.

    Ganau, Mario / Belli, Antonio / Lawrence, Timothy P / Uff, Chris

    Emergency medicine international

    2023  Volume 2023, Page(s) 9754321

    Language English
    Publishing date 2023-04-20
    Publishing country Egypt
    Document type Editorial
    ZDB-ID 2596429-X
    ISSN 2090-2859 ; 2090-2840
    ISSN (online) 2090-2859
    ISSN 2090-2840
    DOI 10.1155/2023/9754321
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  7. Article ; Online: Letter to the Editor Regarding "Burnout Among Neurosurgeons and Residents in Neurosurgery: A Systematic Review and Meta-Analysis of the Literature".

    Ganau, Laura / Ligarotti, Gianfranco K I / Ganau, Mario

    World neurosurgery

    2022  Volume 165, Page(s) 205

    MeSH term(s) Burnout, Professional ; Burnout, Psychological ; Humans ; Neurosurgeons ; Neurosurgery ; Neurosurgical Procedures
    Language English
    Publishing date 2022-10-03
    Publishing country United States
    Document type Journal Article ; Meta-Analysis ; Systematic Review ; Comment
    ZDB-ID 2534351-8
    ISSN 1878-8769 ; 1878-8750
    ISSN (online) 1878-8769
    ISSN 1878-8750
    DOI 10.1016/j.wneu.2022.06.039
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    Zs.A 1159: Show issues Location:
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  8. Article: Imaging in Craniofacial Disorders With Special Emphasis on Gradient Echo Black-Bone and Zero Time Echo MRI Sequences.

    Ganau, Mario / Syrmos, Nikolaos C / Magdum, Shailendra A

    Journal of pediatric neurosciences

    2022  Volume 17, Issue Suppl 1, Page(s) S14–S20

    Abstract: Context: The well-known effects of ionizing radiation on brain cells have been a major driving force toward the use of non-ionizing methods of imaging in both elective and emergency settings. Pediatric neurosurgery has certainly leveraged on this shift ... ...

    Abstract Context: The well-known effects of ionizing radiation on brain cells have been a major driving force toward the use of non-ionizing methods of imaging in both elective and emergency settings. Pediatric neurosurgery has certainly leveraged on this shift in clinical practice, however patients with craniofacial disorders could not fully benefit from the adoption of magnetic resonance imaging (MRI) because computed tomography (CT) scans still retain superior imaging power on bone tissue.
    Aims: To explore the knowledge available on the use of MRI as surrogate for CT scan in the assessment of craniosynostosis.
    Settings and design: A scoping review was designed to identify landmark studies and ongoing clinical trials exploring the accuracy of MRI-based bone imaging in the preoperative planning of pediatric patients with craniosynostosis.
    Materials and methods: A total of 492 records were screened from Pubmed, Ovid Medline, Scopus, and Cochrane Library databases; while 55 records were retrieved from ClinicalTrials.gov register. Only clinical studies revolving around the use of Gradient Echo Black-Bone (BB) and Zero Time Echo (ZTE) MRI sequences for the preoperative planning of pediatric craniosynostosis were retained for inclusion.
    Results and conclusions: This review identified only five clinical studies reporting a high accuracy of MRI-based 3D bone reconstruction in 47 pediatric candidates to surgical correction of craniosynostosis. Although promising, limited evidence (Level IV) exist that BB and ZTE MRI could help in the surgical planning for craniosynostosis management. The results of two ongoing randomized clinical trials, which are actively enrolling patients, will hopefully help answering this research question.
    Language English
    Publishing date 2022-09-19
    Publishing country India
    Document type Journal Article ; Review
    ISSN 1817-1745
    ISSN 1817-1745
    DOI 10.4103/jpn.JPN_46_22
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  9. Article ; Online: Neurological recovery rate and minimal clinically important difference as metrics for assessing outcomes of decompressive surgery in patients with degenerative cervical myelopathy.

    Ganau, Laura / Ligarotti, Gianfranco K I / Ganau, Mario

    Acta neurochirurgica

    2022  Volume 164, Issue 12, Page(s) 3181–3183

    MeSH term(s) Humans ; Minimal Clinically Important Difference ; Benchmarking ; Spinal Cord Diseases/surgery ; Spondylosis/surgery ; Cervical Vertebrae/surgery ; Treatment Outcome
    Language English
    Publishing date 2022-09-22
    Publishing country Austria
    Document type Letter ; Comment
    ZDB-ID 80010-7
    ISSN 0942-0940 ; 0001-6268
    ISSN (online) 0942-0940
    ISSN 0001-6268
    DOI 10.1007/s00701-022-05364-x
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  10. Article ; Online: How SARS-CoV-2 is forcing us to reconsider and reorganize our daily neurosurgical practice.

    Chibbaro, S / Ganau, M / Todeschi, J / Proust, F / Cebula, H

    Neuro-Chirurgie

    2020  Volume 66, Issue 4, Page(s) 189–191

    Keywords covid19
    Language English
    Publishing date 2020-05-13
    Publishing country France
    Document type Editorial
    ZDB-ID 207146-0
    ISSN 1773-0619 ; 0028-3770 ; 0150-9586
    ISSN (online) 1773-0619
    ISSN 0028-3770 ; 0150-9586
    DOI 10.1016/j.neuchi.2020.05.001
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