Article ; Online: Long non-coding RNAs and gastric cancer: An update of potential biomarkers and therapeutic applications.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
2023 Volume 163, Page(s) 114407
Abstract: The frequent metastasis of gastric cancer (GC) complicates the cure and therefore the development of effective diagnostic and therapeutic approaches is urgently necessary. In recent years, lncRNA has emerged as a drug target in the treatment of GC, ... ...
| Abstract | The frequent metastasis of gastric cancer (GC) complicates the cure and therefore the development of effective diagnostic and therapeutic approaches is urgently necessary. In recent years, lncRNA has emerged as a drug target in the treatment of GC, particularly in the areas of cancer immunity, cancer metabolism, and cancer metastasis. This has led to the demonstration of the importance of these RNAs as prognostic, diagnostic and therapeutic agents. In this review, we provide an overview of the biological activities of lncRNAs in GC development and update the latest pathological activities, prognostic and diagnostic strategies, and therapeutic options for GC-related lncRNAs. |
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| MeSH term(s) | Humans ; Stomach Neoplasms/diagnosis ; Stomach Neoplasms/drug therapy ; Stomach Neoplasms/genetics ; RNA, Long Noncoding/genetics ; RNA, Long Noncoding/metabolism ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism | |||||
| Chemical Substances | RNA, Long Noncoding ; Biomarkers, Tumor | |||||
| Language | English | |||||
| Publishing date | 2023-04-24 | |||||
| Publishing country | France | |||||
| Document type | Journal Article ; Review | |||||
| ZDB-ID | 392415-4 | |||||
| ISSN | 1950-6007 ; 0753-3322 ; 0300-0893 | |||||
| ISSN (online) | 1950-6007 | |||||
| ISSN | 0753-3322 ; 0300-0893 | |||||
| DOI | 10.1016/j.biopha.2023.114407 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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