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Book ; Online: O Outro Lado da Moeda

Fernandes, Caio Julio / Ganem, Fernando / Olivieri, Fabio Gravina / Vilibor, Marcelo Fadul / Helito, Alfredo Salim

Arquivos Brasileiros de Cardiologia v.115 n.2 2020

Os Riscos da Discussão de Dados Médico-Científicos pela Mídia Durante a Pandemia de COVID-19

2020

Keywords	Coronavirus ; COVID-19 ; Pandemia ; Quarentena Isolamento Social ; Doenças Respiratórias ; Doenças Transmissíveis ; Diagnóstico Diferencial ; Tecnologia da Informação/tendências ; Mídias Sociais ; covid19
Language	Portuguese
Publishing date	2020-08-01
Publisher	Sociedade Brasileira de Cardiologia - SBC
Publishing country	br
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Seroprevalence of SARS-CoV-2 in Emergency Department Healthcare Workers at Sírio-Libanês Hospital, Brazil.

Madureira, Ricardo / Ferreira, Silvia Aparecida / Marion, Magali Aldrin Lopes / Bettoni, Fabiana / Ganem, Fernando / Camargo, Anamaria Aranha / Morinaga, Christian Valle

Health security

2022 Volume 20, Issue 5, Page(s) 359–367

Abstract: COVID-19 has spread rapidly worldwide. Information on its prevalence and factors associated with infection are important for protecting both professionals and patients in healthcare centers. This study evaluated the seroprevalence of antibodies against ... ...

Abstract	COVID-19 has spread rapidly worldwide. Information on its prevalence and factors associated with infection are important for protecting both professionals and patients in healthcare centers. This study evaluated the seroprevalence of antibodies against SARS-CoV-2 and its association with the degree of exposure and use of personal protective equipment by healthcare professionals dedicated to the treatment of patients with flu-like illnesses in the emergency room. The research team included an analysis of healthcare professionals who underwent enzyme-linked immunosorbent assay serological testing for SARS-CoV-2 between May 28 and June 26, 2020, in the emergency room of Sírio-Libanês Hospital in São Paulo, Brazil. Participants answered individual questionnaires on occupational information, medical health history, and factors associated with exposure to the novel coronavirus. The questionnaire variables were compared based on the serological results. Of the 164 study participants, 96 (58.54%) reported at least 1 flu-like symptom and 42 (25.61%) presented serology results that were compatible with SARS-CoV-2 infection. The asymptomatic declared group accounted for 62 participants; of these, 8 (12.90%) had positive serology results (neutralizing antibody and IgG) for SARS-CoV-2. Data analysis showed a positive correlation with duration of work, safety in wearing and reusing personal protective equipment, and presence of anosmia, and showed a negative relationship with duration of mask use. Our findings suggest that the perception of symptoms by healthcare professionals is not a good screening parameter for the diagnosis of an infectious disease with respiratory symptoms, such as COVID-19. The main influencing factor for the control of infection is the elaboration of workflows and safety protocols based on simple and clear rules as well as investments in team training.
MeSH term(s)	Humans ; SARS-CoV-2 ; COVID-19/epidemiology ; Seroepidemiologic Studies ; Brazil/epidemiology ; Health Personnel ; Hospitals ; Emergency Service, Hospital ; Immunoglobulin G ; Antibodies, Neutralizing
Chemical Substances	sirio ; Immunoglobulin G ; Antibodies, Neutralizing
Language	English
Publishing date	2022-08-12
Publishing country	United States
Document type	Journal Article
ZDB-ID	2823049-8
ISSN	2326-5108 ; 2326-5094
ISSN (online)	2326-5108
ISSN	2326-5094
DOI	10.1089/hs.2022.0045
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: The Other Side of the Coin: Risks of Media Discussions of Scientific Medical Data During the COVID-19 Pandemic.

Fernandes, Caio Julio / Ganem, Fernando / Olivieri, Fabio Gravina / Vilibor, Marcelo Fadul / Helito, Alfredo Salim

Arquivos brasileiros de cardiologia

2020 Volume 115, Issue 2, Page(s) 278–280

Title translation	O Outro Lado da Moeda: Os Riscos da Discussão de Dados Médico-Científicos pela Mídia Durante a Pandemia de COVID-19.
MeSH term(s)	Betacoronavirus ; Biomedical Research/trends ; COVID-19 ; Coronavirus Infections ; Humans ; Mass Media ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
Keywords	covid19
Language	English
Publishing date	2020-09-01
Publishing country	Brazil
Document type	Letter
ZDB-ID	730261-7
ISSN	1678-4170 ; 0066-782X
ISSN (online)	1678-4170
ISSN	0066-782X
DOI	10.36660/abc.20200449
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Stent evaluation by coronary computed tomography angiography: a comparison between Iopamidol-370 and Ioversol-320 hypo-osmolar iodine concentration contrasts.

Garcia, Annelisa Moura / Assunção-Jr, Antonildes N / Dantas-Jr, Roberto Nery / Parga, Jose Rodrigues / Ganem, Fernando

The British journal of radiology

2020 Volume 93, Issue 1115, Page(s) 20200078

Abstract: Objective: Qualitative and quantitative image analysis between Iopamidol-370 and Ioversol-320 in stents´ evaluation by coronary computed tomography angiography (CTA).: Methods: Sixty-five patients with low-risk stable angina undergoing stent follow- ... ...

Abstract	Objective: Qualitative and quantitative image analysis between Iopamidol-370 and Ioversol-320 in stents´ evaluation by coronary computed tomography angiography (CTA). Methods: Sixty-five patients with low-risk stable angina undergoing stent follow-up with coronary CTA were assigned to Iopamidol I-370 ( Results: Image quality was similar between groups, with no significant difference (Likert score 4.48 ± 0.75 Conclusions: There was no significant difference between Iopamidol-370 mgI ml
MeSH term(s)	Angina, Stable/diagnostic imaging ; Angina, Stable/therapy ; Artifacts ; Cardiac Complexes, Premature ; Computed Tomography Angiography/adverse effects ; Computed Tomography Angiography/methods ; Computed Tomography Angiography/standards ; Contrast Media ; Coronary Angiography/adverse effects ; Coronary Angiography/methods ; Coronary Angiography/standards ; Double-Blind Method ; Female ; Heart Rate ; Humans ; Iopamidol ; Male ; Middle Aged ; Multivariate Analysis ; Prohibitins ; Prospective Studies ; Stents/statistics & numerical data ; Triiodobenzoic Acids
Chemical Substances	Contrast Media ; PHB protein, human ; Prohibitins ; Triiodobenzoic Acids ; Iopamidol (JR13W81H44) ; ioversol (N3RIB7X24K)
Language	English
Publishing date	2020-08-20
Publishing country	England
Document type	Comparative Study ; Equivalence Trial ; Journal Article ; Randomized Controlled Trial
ZDB-ID	2982-8
ISSN	1748-880X ; 0007-1285
ISSN (online)	1748-880X
ISSN	0007-1285
DOI	10.1259/bjr.20200078
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Article ; Online: Predicting Hospital Admission and Prolonged Length of Stay in Older Adults in the Emergency Department: The PRO-AGE Scoring System.

Curiati, Pedro K / Gil-Junior, Luiz A / Morinaga, Christian V / Ganem, Fernando / Curiati, Jose A E / Avelino-Silva, Thiago J

Annals of emergency medicine

2020 Volume 76, Issue 3, Page(s) 255–265

Abstract: Study objective: We developed prediction models for hospital admission and prolonged length of stay in older adults admitted from the emergency department (ED).: Methods: This was a retrospective cohort study of patients aged 70 years or older who ... ...

Abstract	Study objective: We developed prediction models for hospital admission and prolonged length of stay in older adults admitted from the emergency department (ED). Methods: This was a retrospective cohort study of patients aged 70 years or older who visited a geriatric ED in Brazil (N=5,025 visits). We randomly allocated participants to derivation and validation samples in a 2:1 ratio. We then selected 21 variables based on their clinical relevance and generated models to predict the following outcomes: hospital admission and prolonged length of stay, defined as the upper tertile of hospital stay. We used backward stepwise logistic regressions to select our final predictors and developed risk scoring systems based on the relative values of their β coefficients. Results: Overall, 57% of the participants were women, 31% were hospitalized, and 1% died in the hospital. The upper tertile of hospital stay was greater than 7 days. Hospital admission was best predicted by a model including male sex, aged 90 years or older, hospitalization in the previous 6 months, weight loss greater than or equal to 5% in the previous year, acute mental alteration, and acute functional decline. The prediction of prolonged length of stay retained the same variables, except male sex, which was substituted for fatigue. The final scoring system reached areas under the receiver operating characteristic curve of 0.74 for hospital admission and 0.79 for prolonged length of stay, and their accuracies were confirmed in the validation models. Conclusion: The PRO-AGE scoring system predicted hospital admission and prolonged length of stay in older adults with good accuracy, using a simple approach and only 7 easily obtained clinical variables.
MeSH term(s)	Age Factors ; Aged ; Aged, 80 and over ; Brazil ; Cohort Studies ; Emergency Service, Hospital/statistics & numerical data ; Female ; Geriatric Assessment ; Health Services for the Aged ; Humans ; Length of Stay ; Logistic Models ; Male ; Models, Theoretical ; Predictive Value of Tests ; Retrospective Studies ; Sex Factors
Language	English
Publishing date	2020-03-31
Publishing country	United States
Document type	Journal Article ; Randomized Controlled Trial
ZDB-ID	603080-4
ISSN	1097-6760 ; 0196-0644
ISSN (online)	1097-6760
ISSN	0196-0644
DOI	10.1016/j.annemergmed.2020.01.010
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Article: O Outro Lado da Moeda: Os Riscos da Discussão de Dados Médico-Científicos pela Mídia Durante a Pandemia de COVID-19./ O Outro Lado da Moeda: Os Riscos da Discussão de Dados Médico-Científicos pela Mídia Durante a Pandemia de COVID-19./ The Other Side of the Coin: Risks of Media Discussions of Scientific Medical Data During the COVID-19 Pandemic

Fernandes, Caio Julio / Ganem, Fernando / Olivieri, Fabio Gravina / Vilibor, Marcelo Fadul / Helito, Alfredo Salim

Arq Bras Cardiol

Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #740657
Database	COVID19

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Article ; Online: Ganglionar tuberculosis infection evolving to hemophagocytic lymphohistiocytosis after anti-programmed cell death 1 treatment for high-risk melanoma: a case report.

Costa, Cesar M / Gadotti, Luiza L / Seiwald, Maria C / Salgues, Alessandra C R / Ganem, Fernando / Nascimento, Ellen C T / Uip, David E / Arrais-Rodrigues, Celso / Munhoz, Rodrigo R

Journal of medical case reports

2021 Volume 15, Issue 1, Page(s) 350

Abstract: Background: Hemophagocytic lymphohistiocytosis is a rare, potentially fatal syndrome of immune hyperactivation. Here we describe a ganglionar tuberculosis evolving to hemophagocytic lymphohistiocytosis following adjuvant immunotherapy in a melanoma ... ...

Abstract	Background: Hemophagocytic lymphohistiocytosis is a rare, potentially fatal syndrome of immune hyperactivation. Here we describe a ganglionar tuberculosis evolving to hemophagocytic lymphohistiocytosis following adjuvant immunotherapy in a melanoma patient. Case presentation: A 76-year-old Caucasian male with melanoma started with fever, diffuse petechiae, splenomegaly, anemia, thrombocytopenia, hypofibrinogenemia, and hyperferritinemia 2 months following completion of adjuvant treatment with nivolumab. Positron emission tomography scan showed significant hypermetabolism in cervical, supraclavicular, mediastinal, and abdominal lymph nodes. Bone marrow aspiration demonstrated no alterations, except for a hypercellular pattern. Dexamethasone and intravenous immunoglobulin were started owing to suspicion of hemophagocytic lymphohistiocytosis. Core biopsy of the infracarinal lymph node revealed a chronic granulomatous inflammation and caseous necrosis, with positivity for Mycobacterium tuberculosis by polymerase chain reaction, and treatment for ganglionar tuberculosis was started. Conclusion: This case highlights the challenges involving programmed cell death 1 blockade in high-risk melanoma, in which infections, lymphoproliferative disorders, and sarcoidosis can mimic disease progression and trigger immune-related adverse events.
MeSH term(s)	Aged ; Humans ; Lymphohistiocytosis, Hemophagocytic/drug therapy ; Male ; Melanoma/drug therapy ; Nivolumab ; Sarcoidosis ; Tuberculosis
Chemical Substances	Nivolumab (31YO63LBSN)
Language	English
Publishing date	2021-07-08
Publishing country	England
Document type	Case Reports ; Journal Article
ZDB-ID	2269805-X
ISSN	1752-1947 ; 1752-1947
ISSN (online)	1752-1947
ISSN	1752-1947
DOI	10.1186/s13256-021-02900-8
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Successive blood pressure measurements to evaluate suspected and treated hypertension.

Vieira da Silva, Marco A / Mendes da Silva, Ana P / Artigas Giorgi, Dante M / Ganem, Fernando

Blood pressure monitoring

2016 Volume 21, Issue 2, Page(s) 69–74

Abstract: Introduction: According to the published literature, blood pressure (BP) measurements performed in the outpatient clinical setting are often inaccurate. The white coat effect and improper technique are the main causes of this imprecision. Construction ... ...

Abstract	Introduction: According to the published literature, blood pressure (BP) measurements performed in the outpatient clinical setting are often inaccurate. The white coat effect and improper technique are the main causes of this imprecision. Construction of a set of readings without them could improve the accuracy of BP measurement. Objective: To evaluate the accuracy and agreement of successive office BP measurements using the awake blood pressure average (ABPa) as the gold standard. Methods: BP was measured in 852 patients using three techniques: in office (OBPa); seven successive measurements performed by a nurse using an automatic device; and 24 h of ambulatory BP monitoring. BP averages (BPa) were obtained from the nurse's measurements: 1-2BPa (first and second), 3-7BPa (third to seventh), and 1-7BPa (first to seventh). OBPa and successive measurements were tested against ABPa by calculating the following: average difference in BP of 1-2BPa, 3-7BPa and OBPa, and the area under the curve. Results: Among the 834 patients eligible, 374 (43.9%) were considered to be hypertensive on the basis of the ABPa (≥135/85 mmHg). 3-7BPa showed the lowest average difference (4/3 mmHg). By contrast, OBPa showed the highest result (21/11 mmHg). The mean difference with 1-2BPa was 8/4 mmHg. The areas under the curve were better with 3-7BPa (0.82-0.85) and 1-2BPa (0.82-0.83) than OBPa (0.67-0.71) for both systolic and diastolic BP. Conclusion: All means from successive measurements showed a better precision than OBPa, even the two first readings. However, more research needs to be carried out before recommendation of the use of this technique in routine practice.
MeSH term(s)	Adolescent ; Adult ; Aged ; Aged, 80 and over ; Blood Pressure ; Blood Pressure Monitoring, Ambulatory ; Female ; Humans ; Hypertension/diagnosis ; Hypertension/physiopathology ; Hypertension/therapy ; Male ; Middle Aged
Language	English
Publishing date	2016-04
Publishing country	England
Document type	Evaluation Studies ; Journal Article
ZDB-ID	1324472-3
ISSN	1473-5725 ; 1359-5237
ISSN (online)	1473-5725
ISSN	1359-5237
DOI	10.1097/MBP.0000000000000161
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Article ; Online: Hiperestimulação ovariana causa tromboembolismo?

Serafini Paulo C. / Ganem Fernando / Cavalheiro Filho Cyrillo

Revista da Associação Médica Brasileira, Vol 49, Iss 3, Pp 230-

2003 Volume 231

Keywords	Medicine (General) ; R5-920 ; Medicine ; R ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
Language	Portuguese
Publishing date	2003-01-01T00:00:00Z
Publisher	Associação Médica Brasileira
Document type	Article ; Online
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Article ; Online: Disseminating cardiopulmonary resuscitation training by distributing 9,200 personal manikins.

de Paiva, Edison Ferreira / Padilha, Roberto de Queiroz / Sgobero, Jenny Karol Gomes Sato / Ganem, Fernando / Cardoso, Luiz Francisco

Academic emergency medicine : official journal of the Society for Academic Emergency Medicine

2014 Volume 21, Issue 8, Page(s) 886–891

Abstract: Objectives: Community members should be trained so that witnesses of cardiac arrests are able to trigger the emergency system and perform adequate resuscitation. In this study, the authors evaluated the results of cardiopulmonary resuscitation (CPR) ... ...

Abstract	Objectives: Community members should be trained so that witnesses of cardiac arrests are able to trigger the emergency system and perform adequate resuscitation. In this study, the authors evaluated the results of cardiopulmonary resuscitation (CPR) training of communities in four Brazilian cities, using personal resuscitation manikins. Methods: In total, 9,200 manikins were distributed in Apucarana, Itanhaém, Maringá, and São Carlos, which are cities where the populations range from 80,000 to 325,000 inhabitants. Elementary and secondary school teachers were trained on how to identify a cardiac arrest, trigger the emergency system, and perform chest compressions. The teachers were to transfer the training to their students, who would then train their families and friends. Results: In total, 49,131 individuals were trained (6.7% of the population), but the original strategy of using teachers and students as multipliers was responsible for only 27.9% of the training. A total of 508 teachers were trained, and only 88 (17.3%) transferred the training to the students. Furthermore, the students have trained only 45 individuals of the population. In Maringá and São Carlos, the strategy was changed and professionals in the primary health care system were prepared and used as multipliers. This strategy proved extremely effective, especially in Maringá, where 39,041 individuals were trained (79.5% of the total number of trainings). Community health care providers were more effective in passing the training to students than the teachers (odds ratio [OR] = 7.12; 95% confidence interval [CI] = 4.74 to 10.69; p < 0.0001). Conclusions: Instruction of CPR using personal manikins by professionals in the primary health care system seems to be a more efficient strategy for training the community than creating a training network in the schools.
MeSH term(s)	Adolescent ; Adult ; Brazil ; Cardiopulmonary Resuscitation/education ; Child ; Community Health Workers ; Education, Nonprofessional/methods ; Education, Nonprofessional/organization & administration ; Faculty ; Female ; Heart Arrest/diagnosis ; Heart Arrest/therapy ; Humans ; Male ; Manikins ; Prospective Studies ; Schools ; Students
Language	English
Publishing date	2014-08
Publishing country	United States
Document type	Journal Article ; Observational Study
ZDB-ID	1329813-6
ISSN	1553-2712 ; 1069-6563
ISSN (online)	1553-2712
ISSN	1069-6563
DOI	10.1111/acem.12423
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