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Book: Studies on respiratory disorders

Ganguly, Nirmal K.

(Oxidative stress in applied basic research and clinical practice)

2014

Author's details	Nirmal K. Ganguly ... ed
Series title	Oxidative stress in applied basic research and clinical practice
Keywords	Respiratory organs/Diseases ; Free radicals (Chemistry)/Pathophysiology ; Antioxidants/Physiological effect
Subject code	616.2
Language	English
Size	XII, 394 S. : Ill., graph. Darst., 24 cm
Publisher	Humana Press
Publishing place	New York u.a.
Publishing country	United States
Document type	Book
Note	Includes bibliographical references
HBZ-ID	HT018280534
ISBN	978-1-4939-0496-9 ; 9781493904976 ; 1-4939-0496-5 ; 1493904973
Database	Catalogue ZB MED Medicine, Health

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Shelf mark	Loan status	Location
2014 A 2170	available for loan (reading room)	Lesesaal EG

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Article: Year-round breast cancer awareness: Empowering young women in the fight against breast cancer.

Kumar, Rakesh / Saini, Sunil / Ganguly, Nirmal K

The Indian journal of medical research

2023 Volume 158, Issue 4, Page(s) 347–349

MeSH term(s)	Female ; Humans ; Breast Neoplasms/diagnosis ; Breast Neoplasms/epidemiology ; Breast Neoplasms/genetics ; Health Promotion ; Mass Screening ; Power, Psychological ; Health Knowledge, Attitudes, Practice ; Awareness
Language	English
Publishing date	2023-09-25
Publishing country	India
Document type	Journal Article
ZDB-ID	390883-5
ISSN	0971-5916 ; 0019-5340
ISSN	0971-5916 ; 0019-5340
DOI	10.4103/ijmr.ijmr_1597_23
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Innovations for the elimination and control of visceral leishmaniasis.

Selvapandiyan, Angamuthu / Croft, Simon L / Rijal, Suman / Nakhasi, Hira L / Ganguly, Nirmal K

PLoS neglected tropical diseases

2019 Volume 13, Issue 9, Page(s) e0007616

MeSH term(s)	Animals ; Asia, Western/epidemiology ; Humans ; Insect Control ; Insect Vectors ; Leishmania donovani/drug effects ; Leishmania donovani/immunology ; Leishmaniasis, Visceral/drug therapy ; Leishmaniasis, Visceral/epidemiology ; Leishmaniasis, Visceral/prevention & control ; Phlebotomus ; Vaccines
Chemical Substances	Vaccines
Language	English
Publishing date	2019-09-19
Publishing country	United States
Document type	Editorial
ZDB-ID	2429704-5
ISSN	1935-2735 ; 1935-2727
ISSN (online)	1935-2735
ISSN	1935-2727
DOI	10.1371/journal.pntd.0007616
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Choice of SARS-CoV-2 diagnostic test: challenges and key considerations for the future.

Baldanti, Fausto / Ganguly, Nirmal K / Wang, Guiqiang / Möckel, Martin / O'Neill, Luke A / Renz, Harald / Dos Santos Ferreira, Carlos Eduardo / Tateda, Kazuhiro / Van Der Pol, Barbara

Critical reviews in clinical laboratory sciences

2022 Volume 59, Issue 7, Page(s) 445–459

Abstract: A plethora of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) diagnostic tests are available, each with different performance specifications, detection methods, and targets. This narrative review aims to summarize the diagnostic technologies ...

Abstract	A plethora of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) diagnostic tests are available, each with different performance specifications, detection methods, and targets. This narrative review aims to summarize the diagnostic technologies available and how they are best selected to tackle SARS-CoV-2 infection as the pandemic evolves. Seven key settings have been identified where diagnostic tests are being deployed: symptomatic individuals presenting for diagnostic testing and/or treatment of COVID-19 symptoms; asymptomatic individuals accessing healthcare for planned non-COVID-19-related reasons; patients needing to access emergency care (symptom status unknown); patients being discharged from healthcare following hospitalization for COVID-19; healthy individuals in both single event settings (e.g. airports, restaurants, hotels, concerts, and sporting events) and repeat access settings (e.g. workplaces, schools, and universities); and vaccinated individuals. While molecular diagnostics remain central to SARS-CoV-2 testing strategies, we have offered some discussion on the considerations for when other tools and technologies may be useful, when centralized/point-of-care testing is appropriate, and how the various additional diagnostics can be deployed in differently resourced settings. As the pandemic evolves, molecular testing remains important for definitive diagnosis, but increasingly widespread point-of-care testing is essential to the re-opening of society.
MeSH term(s)	Humans ; SARS-CoV-2 ; COVID-19 Testing ; COVID-19/diagnosis ; Pandemics ; Point-of-Care Testing ; Sensitivity and Specificity
Language	English
Publishing date	2022-03-15
Publishing country	England
Document type	Review ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	280641-1
ISSN	1549-781X ; 1040-8363 ; 0590-8191
ISSN (online)	1549-781X
ISSN	1040-8363 ; 0590-8191
DOI	10.1080/10408363.2022.2045250
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Cholera toxin: a paradigm of a multifunctional protein.

Bharati, Kaushik / Ganguly, Nirmal K

The Indian journal of medical research

2011 Volume 133, Page(s) 179–187

Abstract: Cholera toxin (CT) was discovered exactly half a century ago by S.N. De. We have come a long way since this epoch-making discovery. Retrospectively, science had to wait a long time since Koch's prediction of the existence of a toxin, and its actual ... ...

Abstract	Cholera toxin (CT) was discovered exactly half a century ago by S.N. De. We have come a long way since this epoch-making discovery. Retrospectively, science had to wait a long time since Koch's prediction of the existence of a toxin, and its actual discovery by De. CT is not just another enterotoxin that causes the signs and symptoms of the dreaded disease, cholera. It is unique in many respects, starting from its structure to its functions. CT is a multifunctional protein that is capable of influencing the immune system in many ways. It not only has remarkable adjuvant properties, but also acts as an anti-inflammatory agent, by modulating specific signal transduction pathways. Its immunomodulatory properties can be harnessed for treatment of various autoimmune disorders, and have shown great promise in the area of immunotherapeutics. CT can truly be considered as a paradigm of a multifunctional protein.
MeSH term(s)	Adenosine Diphosphate/chemistry ; Adenosine Diphosphate/metabolism ; Animals ; Autoimmune Diseases/immunology ; Autoimmune Diseases/therapy ; Cholera Toxin/chemistry ; Cholera Toxin/immunology ; Cholera Vaccines ; Humans ; Immunologic Factors/chemistry ; Immunologic Factors/immunology ; Immunotherapy/methods
Chemical Substances	Cholera Vaccines ; Immunologic Factors ; Adenosine Diphosphate (61D2G4IYVH) ; Cholera Toxin (9012-63-9)
Language	English
Publishing date	2011-03-17
Publishing country	India
Document type	Journal Article ; Review
ZDB-ID	390883-5
ISSN	0971-5916 ; 0019-5340
ISSN	0971-5916 ; 0019-5340
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Q-Rich Yeast Prion [

Verma, Meenakshi / Girdhar, Amandeep / Patel, Basant / Ganguly, Nirmal K / Kukreti, Ritushree / Taneja, Vibha

Frontiers in molecular neuroscience

2018 Volume 11, Page(s) 75

Abstract: Interactions amongst different amyloid proteins have been proposed as a probable mechanism of aggregation and thus an important risk factor for the onset as well as progression of various neurodegenerative disorders including Alzheimer's, Parkinson's, ... ...

Abstract	Interactions amongst different amyloid proteins have been proposed as a probable mechanism of aggregation and thus an important risk factor for the onset as well as progression of various neurodegenerative disorders including Alzheimer's, Parkinson's, Huntington's, and Amyotrophic Lateral Sclerosis. Evidences suggest that transthyretin (TTR), a plasma protein associated with transthyretin amyloidosis or familial polyneuropathy (FAP) interacts with heterologous amyloid proteins including amyloid beta and islet amyloid polypeptide. In addition, recent clinical studies have revealed the presence of systemic polyneuropathy associated with FAP mutations in patients with spinocerebral ataxia, amyotrophic lateral sclerosis, and new familial systematic prion disease. Hence, it is important to investigate the interactions amongst different amyloid proteins to gain better insight into the pathology of amyloid disorders. Yeast has been an excellent model system to study interaction/ cross-seeding between heterologous amyloid proteins, more because of presence of endogenous yeast prions. Here, we examined interactions of non-glutamine (non-Q)-rich transthyretin, with glutamine (Q)-rich yeast prion protein Sup35. We established aggregation of an engineered double (F87M/L110M) mutant M-TTR-GFP in yeast. This mutant is monomeric and readily formed aggregates compared to WT-TTR-GFP in yeast at acidic pH. Interestingly, aggregation of M-TTR-GFP was significantly enhanced in presence of [
Language	English
Publishing date	2018-03-13
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2452967-9
ISSN	1662-5099
ISSN	1662-5099
DOI	10.3389/fnmol.2018.00075
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Are probiotics a feasible intervention for prevention of diarrhoea in the developing world?

Hajela Neerja / Nair Gopinath B / Ganguly Nirmal K

Gut Pathogens, Vol 2, Iss 1, p

2010 Volume 10

Abstract: Abstract With more than 1.4 million of the 9 million child deaths being attributed to diarrhoea in 2008 and 49% of them occurring in five countries namely, India, Nigeria, Democratic Republic of the Congo, Pakistan and China, there is an urgent need for ... ...

Abstract	Abstract With more than 1.4 million of the 9 million child deaths being attributed to diarrhoea in 2008 and 49% of them occurring in five countries namely, India, Nigeria, Democratic Republic of the Congo, Pakistan and China, there is an urgent need for intervention to prevent and control diarrhoeal diseases. Of the various interventions, probiotics offer immense potential. The past decade has witnessed the validation of their utility for the prevention, treatment and management of a variety of infective and non infective disorders. The most investigated field continues to remain infectious diarrhoea and compelling evidence comes from randomized placebo controlled trials. While results from these studies are encouraging most of them reflect the outcomes of the developed world. Developing countries like India continue to struggle with nutritional and health challenges and bear the greatest burden of diarrhoea. A paucity of data from the developing countries limits the definite recommendation of probiotics. In these countries curd, often confused for a probiotic, is practiced as an integral part of the culture. While the nutritional benefits of these products cannot be understated, it is still uncertain whether these products can be classified as a probiotic. The emergence of probiotic foods which are scientifically validated for their efficacy and impart defined health benefits offer an excellent opportunity to improve public health. A recent randomized controlled trial conducted by the National Institute of Cholera and Enteric Diseases in Kolkata, India demonstrated a protective efficacy of 14% in preventing diarrhoea among children who received a probiotic. For the developing world however the vision for probiotics would mean a fundamental change in perception and developing a well planned strategy to allow interventions like probiotics to permeate to impoverished settings, where the assault of micro organisms is on a daily basis. This would mean that probiotics are ingrained into the public health system without being seen as a medicine.
Keywords	Diseases of the digestive system. Gastroenterology ; RC799-869 ; Specialties of internal medicine ; RC581-951 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Gastroenterology ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
Subject code	360
Language	English
Publishing date	2010-08-01T00:00:00Z
Publisher	BioMed Central
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Health impact of probiotics - vision and opportunities

Hajela Neerja / Nair G Balakrish / Abraham Philip / Ganguly Nirmal K

Gut Pathogens, Vol 4, Iss 1, p

2012 Volume 1

Abstract: Abstract Our understanding of the role of the microbiota in our gut and other sites in our body is rapidly emerging and could lead to many new and innovative approaches for health care. The promise of the potential role of probiotics for the prevention ... ...

Abstract	Abstract Our understanding of the role of the microbiota in our gut and other sites in our body is rapidly emerging and could lead to many new and innovative approaches for health care. The promise of the potential role of probiotics for the prevention and treatment of enteric and other infections as an effective solution needs to be realized. The meeting report summarizes the insights and learning from a recent symposium, "Health Impact of Probiotics - Vision and Opportunities" conducted in Mumbai by the Yakult India Microbiota and Probiotic Science Foundation and P.D. Hinduja National Hospital, Mumbai. The symposium reflected its objective of unraveling the potential role of probiotics for health benefits through presentations and discussions. Experts clearly highlighted the role of probiotics in improving various aspects of health and in immune modulation. The report also captures the debate and discussions on the challenges that are likely to be encountered for the use of probiotics in the country.
Keywords	Diseases of the digestive system. Gastroenterology ; RC799-869 ; Specialties of internal medicine ; RC581-951 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Gastroenterology ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
Subject code	360
Language	English
Publishing date	2012-03-01T00:00:00Z
Publisher	BioMed Central
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: The cell based therapy and the policy implications in India.

Mukhopadhyay, Bratati / Basak, Saroj K / Ganguly, Nirmal K

Journal of stem cells

2011 Volume 6, Issue 3, Page(s) 155–179

Abstract: The recent scientific development using stem or other differentiated cells has generated great hopes for treatment of various diseases. Major thrust has been given to formulate country specific laws and regulations considering international guidelines to ...

Abstract	The recent scientific development using stem or other differentiated cells has generated great hopes for treatment of various diseases. Major thrust has been given to formulate country specific laws and regulations considering international guidelines to conduct research and clinical applications of "Cell Based Therapy" (CBT) all over the world. Attempts have made in this review to discuss the current policies that are practiced by various countries in the areas related to CBT with special emphasis on CBT related research and development in India. The two major funding agencies of Government of India e.g. Department of Biotechnology (DBT) and Indian Council of Medical Research (ICMR), have jointly formulated the "Guidelines for Stem Cell Research and Therapy" in 2007 which requires update and revision. Based on the review of the current world scenario of CBT research and development, suggestions have been made for the development of a new CBT policy that will help in progress of research and patient treatment in India.
MeSH term(s)	Animals ; Biomedical Research/economics ; Biomedical Research/legislation & jurisprudence ; Cell Transplantation/adverse effects ; Cell Transplantation/economics ; Cell Transplantation/legislation & jurisprudence ; Dendritic Cells/transplantation ; Endothelial Cells/transplantation ; Genetic Therapy/legislation & jurisprudence ; Government Regulation ; Health Policy/economics ; Health Policy/legislation & jurisprudence ; Humans ; India ; Patient Safety/legislation & jurisprudence ; Practice Guidelines as Topic ; Research Support as Topic/legislation & jurisprudence ; Stem Cell Research/legislation & jurisprudence ; Stem Cell Transplantation/legislation & jurisprudence
Language	English
Publishing date	2011
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Review
ISSN	1556-8539
ISSN	1556-8539
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Book ; Online: Studies on Respiratory Disorders

Ganguly, Nirmal K / Barnes, Peter J / Biswal, Shyam / Jindal, Surinder K / Pawankar, Ruby

(Oxidative Stress in Applied Basic Research and Clinical Practice)

2014

Abstract: Studies on Respiratory Disorders considers the whole panorama of oxidative damage in different respiratory disorders for the review of clinician and laboratory investigators and makes diverse information available in a single volume. This volume ... ...

Author's details	edited by Nirmal K. Ganguly, Surinder K. Jindal, Shyam Biswal, Peter J. Barnes, Ruby Pawankar
Series title	Oxidative Stress in Applied Basic Research and Clinical Practice
Abstract	Studies on Respiratory Disorders considers the whole panorama of oxidative damage in different respiratory disorders for the review of clinician and laboratory investigators and makes diverse information available in a single volume. This volume provides a comprehensive review of numerous studies on the role of oxygen and nitrogen species in lung diseases; it also discusses the potential role of anti-oxidants in their treatment. The contents are organized into three sections along fairly broad classifications: I. General introductory chapters on oxidant stress; general considerations related to reactive oxygen and nitrogen species; the role of exhaled breath condensate and other volatile compounds as exhaled biomarkers of inflammation; II. Oxidative stress in different groups of respiratory disorders such as pulmonary infections (viral, bacterial and tuberculosis); airway diseases such as chronic obstructive pulmonary diseases, air pollution, allergies and asthma; miscellaneous lung diseases (e.g., interstitial diseases, sarcoidosis, asbestosis, respiratory muscle dysfunction, pulmonary hypertension and cancer); and III., Anti-oxidant drugs. These final chapters on anti-oxidant drugs including the mimics (such as traditional herbs) provide a critical review of the available information on their success and failure. Studies on Respiratory Disorders is an important addition to the Oxidative Stress in Applied Basic Research and Clinical Practice series and is essential reading for those treating or researching treatment for respiratory disorders
Keywords	Cytology ; Life sciences ; Pneumology ; Technik / Wissen Biologie
Language	English
Size	Online-Ressource (XII, 394 p. 26 illus., 19 illus. in color), online resource
Publisher	Springer New York
Publishing place	New York, NY ;s.l
Document type	Book ; Online
Note	Description based upon print version of record
ISBN	9781493904969 ; 9781493904976 ; 1493904965 ; 1493904973
DOI	10.1007/978-1-4939-0497-6
Database	Former special subject collection: coastal and deep sea fishing

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