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Article: Effects of smart city construction on employment: mechanism and evidence from China.

Lv, Rongjie / Gao, Hao

2023 , Page(s) 1–33

Abstract: Based on the first batch of smart city pilots in China, this paper systematically investigates the impact of smart city construction on urban employment and employment structure, and its influence mechanism and urban heterogeneity are explored using the ... ...

Abstract	Based on the first batch of smart city pilots in China, this paper systematically investigates the impact of smart city construction on urban employment and employment structure, and its influence mechanism and urban heterogeneity are explored using the difference-in-differences (DID) model. The main conclusions are as follows: (1) Smart city construction significantly promotes urban employment, especially employment in the secondary and tertiary industries. (2) Digital technology development and public services are important mechanisms for smart city construction to improve urban employment. (3) There was heterogeneity among Chinese cities, with the employment promotion effect of smart city construction is primarily reflected in cities located in the eastern and central regions, medium cities, large cities, as well as cities with higher levels of financial development, human capital, and informatization. (4) Through different impacts on various sectors, smart city construction promotes the transfer of employment to the service sector and optimizes the urban employment structure. Conclusions enrich the academic community's understanding of the development and construction of smart cities and provide enlightenment and reference for the formulation and promulgation of relevant supporting policies.
Language	English
Publishing date	2023-05-09
Publishing country	Austria
Document type	Journal Article
ZDB-ID	1462176-9
ISSN	1435-8921 ; 0377-7332
ISSN (online)	1435-8921
ISSN	0377-7332
DOI	10.1007/s00181-023-02429-3
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Article ; Online: Hybrid proton-photon inverse optimization with uniformity-regularized proton and photon target dose.

Gao, Hao

Physics in medicine and biology

2019 Volume 64, Issue 10, Page(s) 105003

Abstract: The goal of radiation therapy is to deliver tumoricidal dose to clinical target volume (CTV) while sparing organs-at-risk (OAR). We hypothesize that the joint use of proton and photon radiation therapy via appropriate hybrid proton-photon inverse ... ...

Abstract	The goal of radiation therapy is to deliver tumoricidal dose to clinical target volume (CTV) while sparing organs-at-risk (OAR). We hypothesize that the joint use of proton and photon radiation therapy via appropriate hybrid proton-photon inverse planning method will be more favorable than proton or photon therapy alone, in terms of optimized combination of CTV coverage and OAR sparing. This work develops hybrid proton-photon inverse optimization method that simultaneously optimizes proton and photon variables. To account for delivery uncertainty, proton dose is targeted at CTV using robust optimization, and photon dose is targeted at either CTV using robust optimization or planning target volume (PTV) using the same setup shifts. The optimization objectives enforce OAR sparing and uniform CTV coverage for the total dose, while imposing uniform-dose regularization at targets for both the proton and photon component in order for both components to be individually deliverable. The hybrid problem with dose-volume-histogram (DVH) constraints is nonconvex and solved by iterative convex relaxations of DVH constraints and alternating direction method of multipliers (ADMM). Preliminary results suggest the hybrid proton-photon planning potentially improves proton or photon planning in terms of optimized combination of CTV coverage and OAR sparing.
MeSH term(s)	Algorithms ; Humans ; Neoplasms/radiotherapy ; Organs at Risk/radiation effects ; Photons/therapeutic use ; Proton Therapy/methods ; Proton Therapy/standards ; Radiotherapy Dosage ; Radiotherapy Planning, Computer-Assisted/methods ; Radiotherapy Planning, Computer-Assisted/standards ; Radiotherapy, Intensity-Modulated/methods ; Radiotherapy, Intensity-Modulated/standards ; Uncertainty
Language	English
Publishing date	2019-05-08
Publishing country	England
Document type	Journal Article
ZDB-ID	208857-5
ISSN	1361-6560 ; 0031-9155
ISSN (online)	1361-6560
ISSN	0031-9155
DOI	10.1088/1361-6560/ab18c7
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Article ; Online: Using LDDMM and a kinematic cardiac growth model to quantify growth and remodelling in rat hearts under PAH.

Guan, Debao / Tian, Lian / Li, Wei / Gao, Hao

Computers in biology and medicine

2024 Volume 171, Page(s) 108218

Abstract: Pulmonary arterial hypertension (PAH) is a rapidly progressive and fatal disease, with right ventricular failure being the primary cause of death in patients with PAH. This study aims to determine the mechanical stimuli that may initiate heart growth and ...

Abstract	Pulmonary arterial hypertension (PAH) is a rapidly progressive and fatal disease, with right ventricular failure being the primary cause of death in patients with PAH. This study aims to determine the mechanical stimuli that may initiate heart growth and remodelling (G&R). To achieve this, two bi-ventricular models were constructed: one for a control rat heart and another for a rat heart with PAH. The growth of the diseased heart was estimated by warping it to the control heart using an improved large deformation diffeomorphic metric mapping (LDDMM) framework. Correlation analysis was then performed between mechanical cues (stress and strain) and growth tensors, which revealed that principal strains may serve as a triggering stimulus for myocardial growth and remodelling under PAH. The growth tensors, estimated from in vivo images, could explain 84.3% of the observed geometrical changes in the diseased heart with PAH by using a kinematic cardiac growth model. Our approach has the potential to quantify G&R using sparse in vivo images and to provide insights into the underlying mechanism of triggering right heart failure from a biomechanical perspective.
MeSH term(s)	Humans ; Rats ; Animals ; Pulmonary Arterial Hypertension ; Hypertension, Pulmonary ; Biomechanical Phenomena ; Heart ; Heart Ventricles
Language	English
Publishing date	2024-02-28
Publishing country	United States
Document type	Journal Article
ZDB-ID	127557-4
ISSN	1879-0534 ; 0010-4825
ISSN (online)	1879-0534
ISSN	0010-4825
DOI	10.1016/j.compbiomed.2024.108218
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Article ; Online: A remarkable new species and one newly recorded species of genus Oxyartes Stl, 1875 (Phasmida, Lonchodidae, Necrosciinae) from China.

Gao, Hao-Ran / Wang, Chen / Zhang, Hong-Rui

Zootaxa

2024 Volume 5419, Issue 3, Page(s) 419–429

Abstract: The genus Oxyartes currently comprises 17 taxa, of which 12 are found in China, representing the high diversity in China. This list includes the two species from China as described in this paper. The first is a new remarkable species O. bouxraeuz sp. nov. ...

Abstract	The genus Oxyartes currently comprises 17 taxa, of which 12 are found in China, representing the high diversity in China. This list includes the two species from China as described in this paper. The first is a new remarkable species O. bouxraeuz sp. nov. collected from Gulinqing township, Yunnan. The second is a newly recorded species, O. cresphontes. This species is reported from Mdog, Xizang, China. A key to this genus from China is presented. Type specimens are deposited in the Yunnan Agricultural University (YNAU).
MeSH term(s)	Humans ; Animals ; China ; Neoptera ; Universities
Language	English
Publishing date	2024-03-07
Publishing country	New Zealand
Document type	Journal Article
ISSN	1175-5334
ISSN (online)	1175-5334
DOI	10.11646/zootaxa.5419.3.6
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Article ; Online: Identification of a Glycerophosphocholine Phosphodiesterase, GDE5, in chicken

Gao Hao / Chang Pingan

E3S Web of Conferences, Vol 245, p

2021 Volume 03054

Abstract: Glycerophosphodiester phosphodiesterase (GDPD/GDE) catalyzes the hydrolysis of glycerophosphodiesters to glycerol 3-phosphate and alcohol. It was discovered that the glycerophosphodiesterase family plays a role in lipid metabolism and signal pathway in ... ...

Abstract	Glycerophosphodiester phosphodiesterase (GDPD/GDE) catalyzes the hydrolysis of glycerophosphodiesters to glycerol 3-phosphate and alcohol. It was discovered that the glycerophosphodiesterase family plays a role in lipid metabolism and signal pathway in recent years, but little has been known about the characteristics of chicken GDEs. Here, chicken GDE5 (cGDE5) was identified and characterized for the first time. The full length coding cDNA sequence of cGDE5 was cloned, which encoded a polypeptide with 678 amino acids containing a carbohydrate-binding module 20 (CBM20) and a GDPD domain. Tissue expression profiles showed that cGDE5 mRNA was high in various tissues. such as heart, brain, skeletal muscle and testis. Moreover, cGDE5 was demonstrated to exhibit glycerophosphocholine phosphodiesterase activity. These results together suggested that cGDE5, as a unique member of GDE family, may play multiple roles as a cytoplasmic glycerophosphocholine phosphodiesterase.
Keywords	Environmental sciences ; GE1-350
Subject code	571
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	EDP Sciences
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: First report of the genus Spinomarmessoidea (Phasmatodea, Lonchodidae, Necrosciinae) from China, with the description of a new species.

Gao, Hao-Ran / Yong-He Li

Zootaxa

2023 Volume 5239, Issue 2, Page(s) 280–288

Abstract: The recently described genus Spinomarmessoidea is comprised of only 2 species from Peninsular Malaysia. The 3rd species of this genus, Spinomarmessoidea damingensis sp. nov. is described from Guangxi Province, China. The new species represents the first ... ...

Abstract	The recently described genus Spinomarmessoidea is comprised of only 2 species from Peninsular Malaysia. The 3rd species of this genus, Spinomarmessoidea damingensis sp. nov. is described from Guangxi Province, China. The new species represents the first record of this genus in China. The granulose head of new species without large spines and mesonotum with short spines are distinguished from the other 2 species. A key to the female of this genus is compiled. Type materials are deposited in the Yunnan Agricultural University (YNAU).
MeSH term(s)	Female ; Animals ; China ; Animal Distribution ; Neoptera ; Universities
Language	English
Publishing date	2023-02-09
Publishing country	New Zealand
Document type	Journal Article
ISSN	1175-5334
ISSN (online)	1175-5334
DOI	10.11646/zootaxa.5239.2.6
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Article ; Online: Effectiveness of social video platforms in promoting smoking cessation among youth: A content-specific analysis of smoking cessation topic videos on the social platform Bilibili.

Ye, Liujiang / Ye, Yijie / Gao, Hao

Tobacco induced diseases

2023 Volume 21, Page(s) 105

Abstract: Introduction: Smoking cessation is a significant public health issue for young people. Social media provide the public with health knowledge through various types of videos. Bilibili is a trendy social video platform among the young population in China, ...

Abstract	Introduction: Smoking cessation is a significant public health issue for young people. Social media provide the public with health knowledge through various types of videos. Bilibili is a trendy social video platform among the young population in China, and the number of smoking cessation videos on this platform is continuously increasing. Different content creators advocating smoking cessation through videos may influence young people's attitudes and behaviors towards tobacco and smoking. This study aims to measure the message sensation value (MSV) and the information appeals in smoking cessation videos on Bilibili, examining their impact on communication effectiveness. Methods: This study collected 337 videos from Bilibili and conducted a content analysis regarding the content creator's information, video presentation, MSV, and message appeals. The communication effectiveness of the videos was defined as a dependent variable and was divided into three dimensions: communication breadth, recognition, and participation. Results: The average MSV (rated on a scale of 0 to 11) for smoking cessation-themed videos was 4.49 (SD=2.23). Chi-squared analysis revealed significant differences among different types of videos in the use of threat appeal (p<0.001), humor appeal (p<0.001), and psychological benefit (p<0.05). Additionally, different types of creators showed differences in the use of threat appeal (p<0.05), humor appeal (p<0.001), and psychological benefit (p<0.05). ANOVA results indicated significant differences in the level of MSV among different smoking cessation videos (F=39.775, p<0.001). Linear regression analysis showed that MSV, threat appeal, humor appeal, and economic benefit positively impacted dissemination effects (p<0.001). Conclusions: The results indicate that young people are likelier to watch smoking cessation videos with higher MSV and information appeal. These elements can enhance persuasion and the effectiveness of communication. Therefore, when video creators aim to promote smoking cessation among young people, they can consider factors such as MSV, threat appeal, humor appeal, and economic benefit to enhance communication effects.
Language	English
Publishing date	2023-08-21
Publishing country	Greece
Document type	Journal Article
ZDB-ID	2194616-4
ISSN	1617-9625 ; 1617-9625
ISSN (online)	1617-9625
ISSN	1617-9625
DOI	10.18332/tid/169662
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Article ; Online: A swap-based sparse array design method in personal sound zone.

Cheng, Jiazheng / Gao, Hao / Feng, Xuelei / Shen, Yong

The Journal of the Acoustical Society of America

2023 Volume 154, Issue 5, Page(s) 2779–2789

Abstract: Sparse array design (SAD) optimizes the geometrical configuration of the loudspeaker array. It provides possibilities for further improving the performance of personal sound zone (PSZ). In this paper, the SAD problem in PSZ is formulated as a sparse ... ...

Abstract	Sparse array design (SAD) optimizes the geometrical configuration of the loudspeaker array. It provides possibilities for further improving the performance of personal sound zone (PSZ). In this paper, the SAD problem in PSZ is formulated as a sparse multi-objective optimization problem, which takes multiple performance metrics into consideration during the sparsity promotion procedure. A swap-based group search algorithm is designed and proposed for solving the formulated non-convex and combinatorial problem to near-optimality. An approximate form is also proposed for reducing computational burden when there exist multiple target sound fields in bright zone. Simulation and experimental results suggest that the proposed method is more suitable in PSZ for controlling over trade-offs and achieving the same good or even better performances, and the proposed approximate form is effective.
Language	English
Publishing date	2023-11-02
Publishing country	United States
Document type	Journal Article
ZDB-ID	219231-7
ISSN	1520-8524 ; 0001-4966
ISSN (online)	1520-8524
ISSN	0001-4966
DOI	10.1121/10.0022048
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Article ; Online: An updated Lagrangian constrained mixture model of pathological cardiac growth and remodelling.

Guan, Debao / Zhuan, Xin / Luo, Xiaoyu / Gao, Hao

Acta biomaterialia

2023 Volume 166, Page(s) 375–399

Abstract: Progressive left ventricular (LV) growth and remodelling (G&R) is often induced by volume and pressure overload, characterized by structural and functional adaptation through myocyte hypertrophy and extracellular matrix remodelling, which are dynamically ...

Abstract	Progressive left ventricular (LV) growth and remodelling (G&R) is often induced by volume and pressure overload, characterized by structural and functional adaptation through myocyte hypertrophy and extracellular matrix remodelling, which are dynamically regulated by biomechanical factors, inflammation, neurohormonal pathways, etc. When prolonged, it can eventually lead to irreversible heart failure. In this study, we have developed a new framework for modelling pathological cardiac G&R based on constrained mixture theory using an updated reference configuration, which is triggered by altered biomechanical factors to restore biomechanical homeostasis. Eccentric and concentric growth, and their combination have been explored in a patient-specific human LV model under volume and pressure overload. Eccentric growth is triggered by overstretching of myofibres due to volume overload, i.e. mitral regurgitation, whilst concentric growth is driven by excessive contractile stress due to pressure overload, i.e. aortic stenosis. Different biological constituent's adaptations under pathological conditions are integrated together, which are the ground matrix, myofibres and collagen network. We have shown that this constrained mixture-motivated G&R model can capture different phenotypes of maladaptive LV G&R, such as chamber dilation and wall thinning under volume overload, wall thickening under pressure overload, and more complex patterns under both pressure and volume overload. We have further demonstrated how collagen G&R would affect LV structural and functional adaption by providing mechanistic insight on anti-fibrotic interventions. This updated Lagrangian constrained mixture based myocardial G&R model has the potential to understand the turnover processes of myocytes and collagen due to altered local mechanical stimuli in heart diseases, and in providing mechanistic links between biomechanical factors and biological adaption at both the organ and cellular levels. Once calibrated with patient data, it can be used for assessing heart failure risk and designing optimal treatment therapies. STATEMENT OF SIGNIFICANCE: Computational modelling of cardiac G&R has shown high promise to provide insight into heart disease management when mechanistic understandings are quantified between biomechanical factors and underlying cellular adaptation processes. The kinematic growth theory has been dominantly used to phenomenologically describe the biological G&R process but neglecting underlying cellular mechanisms. We have developed a constrained mixture based G&R model with updated reference by taking into account different mechanobiological processes in the ground matrix, myocytes and collagen fibres. This G&R model can serve as a basis for developing more advanced myocardial G&R models further informed by patient data to assess heart failure risk, predict disease progression, select the optimal treatment by hypothesis testing, and eventually towards a truly precision cardiology using in-silico models.
MeSH term(s)	Humans ; Heart Failure/pathology ; Collagen/metabolism ; Extracellular Matrix/metabolism ; Ventricular Remodeling ; Aortic Valve Stenosis
Chemical Substances	Collagen (9007-34-5)
Language	English
Publishing date	2023-05-16
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2173841-5
ISSN	1878-7568 ; 1742-7061
ISSN (online)	1878-7568
ISSN	1742-7061
DOI	10.1016/j.actbio.2023.05.022
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Article ; Online: Multizone sound reproduction with adaptive control of scattering effects.

Gao, Hao / Cheng, Jiazheng / Liu, Ziyun / Shen, Yong

The Journal of the Acoustical Society of America

2023 Volume 153, Issue 2, Page(s) 835

Abstract: The aim of multizone sound reproduction is to reproduce different sound programs to different spatial zones in a common space using a set of loudspeakers. Several multizone sound reproduction methods have been developed over the past few decades, and ... ...

Abstract	The aim of multizone sound reproduction is to reproduce different sound programs to different spatial zones in a common space using a set of loudspeakers. Several multizone sound reproduction methods have been developed over the past few decades, and most of them assume that there are no listeners in the listening area. However, when listeners enter the listening area, the scattering effects will reduce the performance of the multizone sound reproduction system. In this paper, an adaptive control method of scattering effects is proposed for multizone sound reproduction. The proposed method models the scattering effects based on the equivalent source method and uses adaptive filters to estimate the scattering effect by a small number of additional microphones. To validate the proposed method, several simulations are presented. The results of the simulations indicate that the proposed adaptive method exhibits good performance when used in multizone sound reproduction with the scattering effects.
Language	English
Publishing date	2023-03-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	219231-7
ISSN	1520-8524 ; 0001-4966
ISSN (online)	1520-8524
ISSN	0001-4966
DOI	10.1121/10.0017101
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