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Article ; Online: Family history, waist circumference and risk of ischemic stroke: A prospective cohort study among Chinese adults

Liu, Lei / Xue, Xiaojia / Zhang, Hua / Tian, Xiaocao / Chen, Yunhui / Guo, Yu / Pei, Pei / Wang, Shaojie / Duan, Haiping / Gao, Ruqin / Pang, Zengchang / Chen, Zhengming / Li, Liming

The Italian Diabetes Society, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition and the Department of Clinical Medicine and Surgery, Federico II University Nutrition, Metabolism and Cardiovascular Diseases. 2023 Apr., v. 33, no. 4 p.758-769

2023

Abstract: The associations between genetic factors and waist circumference (WC) with stroke risk have been evaluated in Western studies. However, evidence of this association has rarely been reported in the Chinese population. This study aimed to evaluate the ... ...

Abstract	The associations between genetic factors and waist circumference (WC) with stroke risk have been evaluated in Western studies. However, evidence of this association has rarely been reported in the Chinese population. This study aimed to evaluate the association between WC and family history of stroke (FHS) with ischemic stroke (IS) risk among Chinese adults and to further explore the potential interaction of these associations. The China Kadoorie Biobank (CKB) study recruited 35,508 participants aged 30–79 years from the Qingdao urban area during 2004–2008. A total of 33,355 participants were included in study. Cox regression analysis was used to estimate the multivariable-adjusted hazard ratios (HR) and 95% confidence intervals (CI) for the independent and interactional associations between FHS and WC and IS risk. Participants with FHS had a 29% (HR = 1.29, 95% CI: 1.12–1.50) higher IS risk than those without FHS. Participants with excessive WC (85 cm for males and 80 cm for females) had a 78% (HR = 1.78, 95% CI: 1.51–2.10) higher IS risk than those with normal WC. The combined effect of FHS and excessive WC on IS was statistically significant (HR = 2.29, 95% CI: 1.84–2.86). The present study further found statistically significant multiplicative interactions of FHS and WC with IS risk (Pᵢₙₜₑᵣₐcₜᵢₒₙ < 0.001). The present study indicated that FHS and WC were significantly associated with an increased risk of IS. The association between FHS and IS was associated with excessive WC.
Keywords	cohort studies ; metabolism ; nutrition ; regression analysis ; risk ; stroke ; urban areas ; waist circumference ; China ; Family history ; Ischemic stroke ; Prospective study
Language	English
Dates of publication	2023-04
Size	p. 758-769.
Publishing place	Elsevier B.V.
Document type	Article ; Online
ZDB-ID	1067704-5
ISSN	0939-4753
ISSN	0939-4753
DOI	10.1016/j.numecd.2023.01.009
Database	NAL-Catalogue (AGRICOLA)

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Article: Preparation of biochemical fulvic acid‐modified diatomite and its adsorption characteristics for tetracycline in water

Gao, Ruqin / Pan, Lu / Zhu, Jiaqi / Li, Youyin / Zhang, Zichang / Yao, Yingli / Liang, Heng / Li, Guoting

Journal of chemical technology and biotechnology. 2022 July, v. 97, no. 7

2022

Abstract: BACKGROUND: Diatomite and biochemical fulvic acid were used as raw materials to prepare biochemical fulvic acid‐modified diatomite using by the sol–gel method. The structure and properties of samples were investigated by X‐ray diffraction, scanning ... ...

Abstract	BACKGROUND: Diatomite and biochemical fulvic acid were used as raw materials to prepare biochemical fulvic acid‐modified diatomite using by the sol–gel method. The structure and properties of samples were investigated by X‐ray diffraction, scanning electron microscopy, etc. The effects of solution pH and reaction temperature on the adsorption performance of adsorption materials were evaluated by taking tetracycline as the target pollutant. The adsorption kinetics, adsorption rate mechanism and adsorption isotherm of tetracycline were revealed. RESULTS: The results showed that the main form of diatomite is amorphous SiO₂. The surface and channels of diatomite were loaded with biochemical fulvic acid, and the specific surface area of the modified material increased from 9.182 to 13.774 m² g⁻¹, while the average pore size decreased from 10.972 to 7.15 nm. The pH of the tetracycline solution was 5 and the initial concentration was 20 mg L⁻¹; the adsorption capacity of the modified sample increased 1.93‐fold to 29.84 mg g⁻¹. When the adsorption temperature was increased from 10 to 60 °C, the adsorption capacity of the modified material increased nearly fourfold, reaching 78.8 mg g⁻¹. CONCLUSION: Quasi‐second‐order reaction kinetics has a correlation coefficient R² of 0.993, which suggests a good fit to the adsorption process of tetracycline by the modified diatomite. Both Freundlich and Redlich–Peterson adsorption isotherm equations can elucidate the adsorption process of the composites. The adsorption is heterogeneous adsorption on the surface, mainly multi‐layer adsorption and electrostatic attraction adsorption. © 2022 Society of Chemical Industry (SCI).
Keywords	X-ray diffraction ; adsorption ; biotechnology ; diatomaceous earth ; electrostatic interactions ; fulvic acids ; pH ; pollutants ; porosity ; reaction kinetics ; sol-gel processing ; sorption isotherms ; surface area ; temperature ; tetracycline
Language	English
Dates of publication	2022-07
Size	p. 1803-1812.
Publishing place	John Wiley & Sons, Ltd.
Document type	Article
Note	JOURNAL ARTICLE
ZDB-ID	1479465-2
ISSN	1097-4660 ; 0268-2575
ISSN (online)	1097-4660
ISSN	0268-2575
DOI	10.1002/jctb.7051
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Article ; Online: Environmental contamination of a quarantine hotel via SARS-CoV-2 positive travellers.

Hu, Xiaowen / Liu, Ziran / Liang, Jiwei / Song, Xin / Wang, Zhaoguo / Gao, Ruqin / Jiang, Fachun

Journal of travel medicine

2021 Volume 28, Issue 8

MeSH term(s)	COVID-19 ; Humans ; Quarantine ; SARS-CoV-2 ; Travel
Language	English
Publishing date	2021-10-12
Publishing country	England
Document type	Journal Article
ZDB-ID	1212504-0
ISSN	1708-8305 ; 1195-1982
ISSN (online)	1708-8305
ISSN	1195-1982
DOI	10.1093/jtm/taab148
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Article ; Online: Association between dairy consumption and ischemic heart disease among Chinese adults: a prospective study in Qingdao

Song, Jiahui / Pan, Chi / Li, Feifei / Guo, Yu / Pei, Pei / Tian, Xiaocao / Wang, Shaojie / Gao, Ruqin / Pang, Zengchang / Chen, Zhengming / Li, Liming

Nutr Metab (Lond). 2022 Dec., v. 19, no. 1 p.11-11

2022

Abstract: BACKGROUND: Previous studies linking dairy consumption with ischemic heart disease (IHD) are almost from western countries, with little from China. The present study was to explore the relationship between dairy consumption and IHD among Chinese adults. ... ...

Abstract	BACKGROUND: Previous studies linking dairy consumption with ischemic heart disease (IHD) are almost from western countries, with little from China. The present study was to explore the relationship between dairy consumption and IHD among Chinese adults. METHODS: The data for the present study was from the prospective cohort study of China Kadoorie Biobank in Qingdao, a total of 33,355 participants in the present study. An interviewer-administered laptop-based questionnaire was used to collect information on the consumption frequency of dairy, incident IHD cases were identified through Disease Surveillance Point System and the new national health insurance databases. Cox regression analyses were performed to estimate adjusted hazard ratios (HRs) and confidence interval for the relationship between the incidence of IHD and dairy consumption. RESULTS: The baseline survey reported that 32.4% of males and 34.6% of females consumed dairy regularly (i.e. ≥ 4 days/week). Over an average of 9.2 years follow-up, 2712 new-onset IHD were documented. Compared with participants who never or rarely consume dairy, the HR of consumed dairy regularly was 0.85(0.73–0.98) for males (P < 0.05), while no significant benefits were identified for females. CONCLUSIONS: Regular dairy consumption had an inverse association to the onset of IHD among males, with no similar findings for females.
Keywords	confidence interval ; dairy consumption ; disease surveillance ; health insurance ; myocardial ischemia ; prospective studies ; questionnaires ; regression analysis ; China
Language	English
Dates of publication	2022-12
Size	p. 11.
Publishing place	BioMed Central
Document type	Article ; Online
ZDB-ID	2160376-5
ISSN	1743-7075
ISSN	1743-7075
DOI	10.1186/s12986-022-00645-9
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Article ; Online: Detection of SARS-CoV-2 in Different Types of Clinical Specimens.

Wang, Wenling / Xu, Yanli / Gao, Ruqin / Lu, Roujian / Han, Kai / Wu, Guizhen / Tan, Wenjie

JAMA

2020 Volume 323, Issue 18, Page(s) 1843–1844

MeSH term(s)	Adolescent ; Adult ; Aged ; Betacoronavirus/isolation & purification ; Bronchoalveolar Lavage Fluid/virology ; Bronchoscopy/statistics & numerical data ; COVID-19 ; Child ; Child, Preschool ; China ; Coronavirus Infections/blood ; Coronavirus Infections/urine ; Coronavirus Infections/virology ; Feces/virology ; Female ; Gene Dosage ; Genes, Viral ; Humans ; Male ; Middle Aged ; Nose/virology ; Open Reading Frames ; Pandemics ; Pharynx/virology ; Pneumonia, Viral/blood ; Pneumonia, Viral/urine ; Pneumonia, Viral/virology ; RNA, Viral/isolation & purification ; Real-Time Polymerase Chain Reaction ; SARS-CoV-2 ; Sputum/virology ; Viral Load ; Young Adult
Chemical Substances	RNA, Viral
Keywords	covid19
Language	English
Publishing date	2020-01-27
Publishing country	United States
Document type	Journal Article ; Multicenter Study ; Research Support, Non-U.S. Gov't
ZDB-ID	2958-0
ISSN	1538-3598 ; 0254-9077 ; 0002-9955 ; 0098-7484
ISSN (online)	1538-3598
ISSN	0254-9077 ; 0002-9955 ; 0098-7484
DOI	10.1001/jama.2020.3786
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Article ; Online: The Prospective Associations of Egg Consumption with the Risk of Total Cerebrovascular Disease Morbidity among Chinese Adults.

Pan, Chi / Sun, Xiaohui / Song, Jiahui / Yu, Canqing / Guo, Yu / Wang, Shaojie / Gao, Ruqin / Ning, Feng / Pang, Zengchang / Chen, Zhengming / Li, Liming

Nutrients

2023 Volume 15, Issue 8

Abstract: Background: Studies investigating the relationship between egg consumption and the risk of cerebrovascular disease (CED) have yielded inconsistent results. This study evaluated the association between egg consumption and the risk of CED among Chinese ... ...

Abstract	Background: Studies investigating the relationship between egg consumption and the risk of cerebrovascular disease (CED) have yielded inconsistent results. This study evaluated the association between egg consumption and the risk of CED among Chinese adults. Methods: Data were obtained from China Kadoorie Biobank, Qingdao. A computerised questionnaire was used to collect information regarding egg consumption frequency. CED events were tracked through linkage with the Disease Surveillance Point System and the new national health insurance databases. Cox proportional hazards regression analyses were used to evaluate associations between egg consumption and CED risk controlling for potential confounders. Results: After a median follow-up of 9.2 years, 865 and 1083 CED events among men and women, respectively, were documented. More than 50% of participants consumed eggs daily with an average age of 52.0 (10.4) years at baseline. No association between egg consumption and CED were identified in the whole cohort and women. However, a 28% lower risk of CED was observed in those who consumed eggs at a higher frequency (HR = 0.72, 95% CI: 0.55-0.95) and a significant trend for the association ( Conclusion: Higher frequency of egg consumption was associated with a lower risk of total CED events among men but not women in Chinese adults. The beneficial effect on women warrants further investigations.
MeSH term(s)	Adult ; Humans ; Male ; Middle Aged ; Cerebrovascular Disorders/epidemiology ; Cerebrovascular Disorders/etiology ; China/epidemiology ; East Asian People ; Eggs ; Morbidity ; Prospective Studies ; Risk Factors ; Female
Language	English
Publishing date	2023-04-07
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu15081808
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Family history, waist circumference and risk of ischemic stroke: A prospective cohort study among Chinese adults.

Liu, Lei / Xue, Xiaojia / Zhang, Hua / Tian, Xiaocao / Chen, Yunhui / Guo, Yu / Pei, Pei / Wang, Shaojie / Duan, Haiping / Gao, Ruqin / Pang, Zengchang / Chen, Zhengming / Li, Liming

Nutrition, metabolism, and cardiovascular diseases : NMCD

2023 Volume 33, Issue 4, Page(s) 758–769

Abstract: Background and aims: The associations between genetic factors and waist circumference (WC) with stroke risk have been evaluated in Western studies. However, evidence of this association has rarely been reported in the Chinese population. This study ... ...

Abstract	Background and aims: The associations between genetic factors and waist circumference (WC) with stroke risk have been evaluated in Western studies. However, evidence of this association has rarely been reported in the Chinese population. This study aimed to evaluate the association between WC and family history of stroke (FHS) with ischemic stroke (IS) risk among Chinese adults and to further explore the potential interaction of these associations. Methods and results: The China Kadoorie Biobank (CKB) study recruited 35,508 participants aged 30-79 years from the Qingdao urban area during 2004-2008. A total of 33,355 participants were included in study. Cox regression analysis was used to estimate the multivariable-adjusted hazard ratios (HR) and 95% confidence intervals (CI) for the independent and interactional associations between FHS and WC and IS risk. Participants with FHS had a 29% (HR = 1.29, 95% CI: 1.12-1.50) higher IS risk than those without FHS. Participants with excessive WC (85 cm for males and 80 cm for females) had a 78% (HR = 1.78, 95% CI: 1.51-2.10) higher IS risk than those with normal WC. The combined effect of FHS and excessive WC on IS was statistically significant (HR = 2.29, 95% CI: 1.84-2.86). The present study further found statistically significant multiplicative interactions of FHS and WC with IS risk (P Conclusion: The present study indicated that FHS and WC were significantly associated with an increased risk of IS. The association between FHS and IS was associated with excessive WC.
MeSH term(s)	Adult ; Female ; Humans ; Male ; Body Mass Index ; China/epidemiology ; East Asian People/statistics & numerical data ; Ischemic Stroke/ethnology ; Ischemic Stroke/etiology ; Prospective Studies ; Risk Factors ; Waist Circumference ; Medical History Taking ; Family ; Middle Aged ; Aged ; Urban Population
Language	English
Publishing date	2023-01-18
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1067704-5
ISSN	1590-3729 ; 0939-4753
ISSN (online)	1590-3729
ISSN	0939-4753
DOI	10.1016/j.numecd.2023.01.009
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Article: Famine exposure in early life and type 2 diabetes in adulthood: findings from prospective studies in China.

Ning, Feng / Zhao, Jing / Zhang, Lei / Wang, Weijing / Sun, Xiaohui / Song, Xin / Zhang, Yanlei / Xin, Hualei / Gao, Weiguo / Gao, Ruqin / Zhang, Dongfeng / Pang, Zengchang

Nutrition research and practice

2023 Volume 17, Issue 4, Page(s) 780–788

Abstract: Background/objectives: This study examined the relationship between famine exposure in early life and the risk of type 2 diabetes in adulthood during the 1959-1961 Chinese Famine.: Subjects/methods: A total of 3,418 individuals aged 35-74 years free ... ...

Abstract	Background/objectives: This study examined the relationship between famine exposure in early life and the risk of type 2 diabetes in adulthood during the 1959-1961 Chinese Famine. Subjects/methods: A total of 3,418 individuals aged 35-74 years free of diabetes from two studies in 2006 and 2009 were followed up prospectively in 2009 and 2012, respectively. Famine exposure was classified as unexposed (individuals born in 1962-1978), fetal exposed (individuals born in 1959-1961), child exposed (individuals born in 1949-1958), and adolescent/adult exposed (born in 1931-1948). A logistic regression model was used to assess the relationship between famine exposure and diabetes after adjustment for potential covariates. Results: During a three-year follow-up, the age-adjusted incidence rates of type 2 diabetes were 5.7%, 14.5%, 12.7%, and 17.8% in unexposed, fetal-exposed, child-exposed, and adolescent/adult-exposed groups, respectively ( Conclusions: These findings indicate that famine exposure in early life is an independent predictor of type 2 diabetes, particularly in women. Early identification and intervention may help prevent diabetes in later life. Trial registration: ClinicalTrials.gov Identifier: NCT01053195.
Language	English
Publishing date	2023-03-13
Publishing country	Korea (South)
Document type	Journal Article
ZDB-ID	2387946-4
ISSN	2005-6168 ; 1976-1457
ISSN (online)	2005-6168
ISSN	1976-1457
DOI	10.4162/nrp.2023.17.4.780
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Article ; Online: A Nosocomial COVID-19 Outbreak Initiated by an Infected Dockworker at Qingdao City Port - Shandong Province, China, October, 2020.

Yuan, Qun / Kou, Zengqiang / Jiang, Fachun / Li, Zhongjie / Zhang, Lijie / Liu, Huihui / Zhao, Xiang / Kang, Dianmin / Gao, Ruqin / Lei, Jie

China CDC weekly

2021 Volume 2, Issue 43, Page(s) 838–840

Language	English
Publishing date	2021-08-29
Publishing country	China
Document type	Journal Article
ISSN	2096-7071
ISSN (online)	2096-7071
DOI	10.46234/ccdcw2020.224
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Article ; Online: Preliminary evidence for an influence of exposure to polycyclic aromatic hydrocarbons on the composition of the gut microbiota and neurodevelopment in three-year-old healthy children.

Zhang, Wei / Sun, Zhongqing / Zhang, Qian / Sun, Zhitao / Su, Ya / Song, Jiahui / Wang, Bingling / Gao, Ruqin

BMC pediatrics

2021 Volume 21, Issue 1, Page(s) 86

Abstract: Background: During the second and third year after birth the gut microbiota (GM) is subjected to important development. The polycyclic aromatic hydrocarbon (PAH) exposure could influence the GM in animal and early postnatal exposure is associated with ... ...

Abstract	Background: During the second and third year after birth the gut microbiota (GM) is subjected to important development. The polycyclic aromatic hydrocarbon (PAH) exposure could influence the GM in animal and early postnatal exposure is associated with neurodevelopment disorder in children. This study was designed to explore the possible influence of the polycyclic aromatic hydrocarbons (PAHs) on the composition of the gut microbiota (GM) and neurodevelopment in a sample of 38 healthy children at the age of 3 years. Methods: A brief development (Gesell Development Inventory, GDI) and behavior test (Child Behavior Checklist, CBCL) were completed on 3-yr-olds and stool samples were collected for 16S rRNA V4-V5 sequencing. The PAH-DNA adduct in the umbilical cord blood and the urinary hydroxyl PAHs (OH-PAHs) at the age of 12 months were measured as pre- and postnatal PAH exposure, respectively. Results: The most abundant two phyla were Bacteroidetes (68.6%) and Firmicutes (24.2%). The phyla Firmicutes, Actinobacteria, Proteobacteria, Tenericutes, and Lentisphaerae were positively correlated with most domain behaviors of the GDI, whereas the Bacteroidetes, Cyanobacteria, and Fusobacteria were negatively correlated. Correspondingly, the phyla Bacteroidetes, Actinobacteria, and Fusobacteria showed positive correlations with most CBCL core and broadband syndromes, whereas the Firmicutes, Verrucomicrobia, Synergistetes, Proteobacteria and Tenericules were negatively correlated. The OH-PAH levels were not significantly associated with the Firmicutes phylum whereas the Bacteroidetes, Bacteroidia, and Bacteroidales all showed significant negative association with the OH-PAH levels. Conclusion: The current findings suggest that composition of the GM is associated with neurodevelopment of the child. PAHs seem to change the relative abundance of some taxa (some deleted and some recruited) to counteract the negative effects of the PAHs.
MeSH term(s)	Bacteria ; Child ; Child, Preschool ; Fetal Blood ; Gastrointestinal Microbiome ; Humans ; Infant ; Polycyclic Aromatic Hydrocarbons/toxicity ; RNA, Ribosomal, 16S/genetics
Chemical Substances	Polycyclic Aromatic Hydrocarbons ; RNA, Ribosomal, 16S
Language	English
Publishing date	2021-02-17
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2041342-7
ISSN	1471-2431 ; 1471-2431
ISSN (online)	1471-2431
ISSN	1471-2431
DOI	10.1186/s12887-021-02539-w
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