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  1. Article ; Online: Assessing fresh water acute toxicity with Surface-Enhanced Raman Scattering (SERS).

    Gao, Weixing / Fan, Wanli / Wang, Dongmei / Sun, Ji / Li, Yong / Tang, Changyu / Fan, Meikun

    Talanta

    2023  Volume 267, Page(s) 125163

    Abstract: It's well known that the toxicity of chemicals in the environment depends not only their concentrations, but more importantly, their bio-availability. Thus, the acute toxicity test of environmental water samples is of great importance in water quality ... ...

    Abstract It's well known that the toxicity of chemicals in the environment depends not only their concentrations, but more importantly, their bio-availability. Thus, the acute toxicity test of environmental water samples is of great importance in water quality evaluation. In this work, water acute toxicity was determined via SERS approach for the first time based on the reaction between Escherichia coli (E. coli) and p-benzoquinone (BQ). The E. coli was used as the subject of toxicity assay. Under normal conditions, the BQ molecules can be transformed into Hydroquinone (HQ) by the E. coli bacteria; subsequently, the BQ will continue to react with the resulting HQ to form Quinone hydroquinone (QHQ). This process could be impaired in the presence of many toxic chemicals. Bromide modified Ag NPs was then introduced for the highly sensitive SERS detection of the product (HQ and QHQ). Several key factors that may affect water acute toxicity evaluation have been explored, which include the initial BQ and E. coli concentration, the incubation time with BQ, and the sodium chloride concentration. Later, the established system was applied for the toxicity evaluation of Cu
    MeSH term(s) Escherichia coli ; Hydroquinones/toxicity ; Spectrum Analysis, Raman/methods ; Metal Nanoparticles/toxicity ; Metal Nanoparticles/chemistry
    Chemical Substances hydroquinone (XV74C1N1AE) ; Hydroquinones
    Language English
    Publishing date 2023-09-08
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1500969-5
    ISSN 1873-3573 ; 0039-9140
    ISSN (online) 1873-3573
    ISSN 0039-9140
    DOI 10.1016/j.talanta.2023.125163
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Highly sensitive SERS detection of residual nitrofurantoin and 1-amino-hydantoin in aquatic products and feeds.

    Fan, Wanli / Gao, Weixing / Jiao, Jian / Wang, Dongmei / Fan, Meikun

    Luminescence : the journal of biological and chemical luminescence

    2021  Volume 37, Issue 1, Page(s) 82–88

    Abstract: Nitrofurantoin (NFT), a typical highly effective nitrofuran antibiotic drug, has been prohibited but still widely found in animal food products. It can be metabolized in animals to form 1-amino-hydantoin (AHD) that can then form stable and toxic ... ...

    Abstract Nitrofurantoin (NFT), a typical highly effective nitrofuran antibiotic drug, has been prohibited but still widely found in animal food products. It can be metabolized in animals to form 1-amino-hydantoin (AHD) that can then form stable and toxic metabolite-protein adducts. Hence, the detection of NFT and AHD in aquatic products and feeds is very important. However, there are limited reports concerning NFT detection and none about AHD by using surface-enhanced Raman spectroscopy (SERS) method. Herein, potassium bromide (KBr) decorated silver (Ag) nanoparticles (Ag-BrNPs)-based SERS approach was proposed for NFT and AHD detection. The limit of detection (LOD) for NFT was 1 μg/L. The detection of NFT residues in sea cucumber and fish feeds was also realized with the LOD of 1 and 50 ng/g, respectively. More importantly, the sensing of AHD was easily realized with the SERS approach for the first time. After the derivatization with 2-nitrobenzaldehyde (2-NBA), Ag-BrNPs were also successfully utilized for AHD detection in sea cucumber with the LOD of 5 ng/g.
    MeSH term(s) Animals ; Hydantoins ; Limit of Detection ; Metal Nanoparticles ; Nitrofurantoin ; Silver ; Spectrum Analysis, Raman
    Chemical Substances Hydantoins ; Silver (3M4G523W1G) ; Nitrofurantoin (927AH8112L)
    Language English
    Publishing date 2021-10-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 1470995-8
    ISSN 1522-7243 ; 1522-7235 ; 1099-1271
    ISSN (online) 1522-7243
    ISSN 1522-7235 ; 1099-1271
    DOI 10.1002/bio.4148
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: CD300e: Emerging role and mechanism as an immune-activating receptor.

    Liu, Na / Sun, Wenchang / Gao, Weixing / Yan, Shushan / Yang, Chunjuan / Zhang, Jin / Ni, Biao / Zhang, Lili / Zang, Jie / Zhang, Sue / Xu, Donghua

    International immunopharmacology

    2024  Volume 133, Page(s) 112055

    Abstract: As a transmembrane protein, CD300e is primarily expressed in myeloid cells. It belongs to the CD300 glycoprotein family, functioning as an immune-activating receptor. Dysfunction of CD300e has been suggested in many diseases, such as infections, immune ... ...

    Abstract As a transmembrane protein, CD300e is primarily expressed in myeloid cells. It belongs to the CD300 glycoprotein family, functioning as an immune-activating receptor. Dysfunction of CD300e has been suggested in many diseases, such as infections, immune disorders, obesity, and diabetes, signifying its potential as a key biomarker for disease diagnosis and treatment. This review is aimed to explore the roles and potential mechanisms of CD300e in regulating oxidative stress, immune cell activation, tissue damage and repair, and lipid metabolism, shedding light on its role as a diagnostic marker or a therapeutic target, particularly for infections and autoimmune disorders.
    Language English
    Publishing date 2024-04-26
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 2043785-7
    ISSN 1878-1705 ; 1567-5769
    ISSN (online) 1878-1705
    ISSN 1567-5769
    DOI 10.1016/j.intimp.2024.112055
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: An ERP study on the influence of mental abacus calculation on subthreshold arithmetic priming in children.

    Wang, Cong-Cong / Sun, Yan-Chao / Zhang, Yu / Xin, Yan-Wei / Gao, Wei-Xing / Jia, Li-Ping / Liu, Xiao-Qin

    Neuroreport

    2022  Volume 33, Issue 3, Page(s) 116–128

    Abstract: Objective: The objective of this study was to investigate the influence of mental abacus calculation training (MACT) on subliminal cognitive processes.: Methods: Twenty children with intensive MACT (MACT group) and 20 children without MACT (non-MACT ... ...

    Abstract Objective: The objective of this study was to investigate the influence of mental abacus calculation training (MACT) on subliminal cognitive processes.
    Methods: Twenty children with intensive MACT (MACT group) and 20 children without MACT (non-MACT group) were selected. The two groups of children were matched in age, sex, handedness and academic grade. The participants were tested with subthreshold arithmetic priming task while their neural activities were recorded with a 32-channel electroencephalogram system.
    Results: We found that MACT changed the subliminal cognitive mechanism of computational processing, speeding up the computation. MACT affected the computational processing mode. Specifically, in the identification stage, both groups of children adopted the visual space processing mode, while in the computing stage, the MACT group adopted a visual space processing mode, but the non-MACT group adopted a semantic processing mode. Moreover, MACT improved children's executive functions.
    Conclusion: These results yielded insights into the effect of early abacus training on children's cognitive processing, providing a theoretical basis for the development and promotion of abacus training.
    MeSH term(s) Brain ; Child ; Electroencephalography ; Executive Function ; Humans ; Mathematics
    Language English
    Publishing date 2022-02-09
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1049746-8
    ISSN 1473-558X ; 0959-4965
    ISSN (online) 1473-558X
    ISSN 0959-4965
    DOI 10.1097/WNR.0000000000001761
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Estimating loss of life caused by dam breaches based on the simulation of floods routing and evacuation potential of population at risk

    Ge, Wei / Jiao, Yutie / Wu, Meimei / Li, Zongkun / Wang, Te / Li, Wei / Zhang, Yadong / Gao, Weixing / van Gelder, Pieter

    Journal of hydrology. 2022 June 09,

    2022  

    Abstract: Dam breaches often have catastrophic consequences in downstream areas. Hydrodynamic factors and the evacuation potential of the population at risk (PAR) have significant impacts on the loss of life (LOL) caused by dam breaches. However, the existing ... ...

    Abstract Dam breaches often have catastrophic consequences in downstream areas. Hydrodynamic factors and the evacuation potential of the population at risk (PAR) have significant impacts on the loss of life (LOL) caused by dam breaches. However, the existing comprehensive evaluation models have not conducted in-depth research on the evacuation potential of populations. Thus, limited guidance is available for relevant departments to formulate emergency plans to reduce the potential LOL. Therefore, a new comprehensive evaluation model was proposed in this study. According to the relevant references and disaster theory, the main influencing factors and the process through which the LOL is caused by dam breaches were determined. The specific occurrence process was divided into six stages: a dam breach causes flood, the flood puts the PAR, the PAR complete the preparation work, the PAR evacuate, the un-evacuated population shelter themselves inside buildings, and flood causes the death of the exposed population. To calculate the LOL, the parameters relevant at each stage were defined. Furthermore, the Hydrologic Engineering Center’s River Analysis System, Geographic Information System, and related materials were used to simulate the flood routing and evacuation potential of the PAR, quantifying the parameters in the model. The model was applied to 14 towns in the downstream areas of the Luhun Reservoir in Henan Province, China, and its accuracy was verified by comparing the results obtained from the two existing models. In addition, the specific suggestions for reducing the potential LOL were proposed based on the results of the simulation.
    Keywords at-risk population ; death ; geographic information systems ; hydrodynamics ; models ; rivers ; China
    Language English
    Dates of publication 2022-0609
    Publishing place Elsevier B.V.
    Document type Article
    Note Pre-press version
    ZDB-ID 1473173-3
    ISSN 1879-2707 ; 0022-1694
    ISSN (online) 1879-2707
    ISSN 0022-1694
    DOI 10.1016/j.jhydrol.2022.128059
    Database NAL-Catalogue (AGRICOLA)

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  6. Article ; Online: Economic risk criteria for dams considering the relative level of economy and industrial economic contribution.

    Ge, Wei / Sun, Heqiang / Zhang, Hexiang / Li, Zongkun / Guo, Xinyan / Wang, Xiuwei / Qin, Yupan / Gao, Weixing / van Gelder, Pieter

    The Science of the total environment

    2020  Volume 725, Page(s) 138139

    Abstract: When a dam breaks, huge floods will be generated that may inundate urban areas, enterprises, farmlands, and infrastructure and cause giant economic losses. Economic risk criteria are a kind of basis for determining dam risk levels and to decide whether ... ...

    Abstract When a dam breaks, huge floods will be generated that may inundate urban areas, enterprises, farmlands, and infrastructure and cause giant economic losses. Economic risk criteria are a kind of basis for determining dam risk levels and to decide whether risk control measures should be taken or not. However, compared to loss-of-life risk criteria, much fewer economic risk criteria for dams have been proposed and implemented for two main reasons: (a) The ability of most areas to endure economic losses caused by dam breach changes over time because of the constant development of their economic levels; and (b) Economic development levels in an area are distinct from the levels in other areas, resulting in significant differences in the ability of different areas to endure economic losses caused by a dam breach. Therefore, an equivalent economic scale (EES) that indicates the relative economic level of an area to the whole country in a given period of time is a preferred measure. It was shown in this paper that EES has much more stable values than do ordinary economic measures; therefore, it was taken as the basic index for establishing economic risk criteria. Furthermore, due to the distinct economic loss rates of different industries, the index of industrial economic contribution (IEC) was introduced to determine the correction coefficient to modify the ESS to reflect the potential economic loss of the area to be evaluated. This is the first research that pays careful attention to the change of ability to endure economic losses, in which the established economic risk criteria are applicable over a relatively long time and for different areas based on the consideration of the relative level of the economy and the industrial economic contribution.
    Language English
    Publishing date 2020-03-23
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2020.138139
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Economic risk criteria for dams considering the relative level of economy and industrial economic contribution

    Ge, Wei / Sun, Heqiang / Zhang, Hexiang / Li, Zongkun / Guo, Xinyan / Wang, Xiuwei / Qin, Yupan / Gao, Weixing / van Gelder, Pieter

    Science of the total environment. 2020 July 10, v. 725

    2020  

    Abstract: When a dam breaks, huge floods will be generated that may inundate urban areas, enterprises, farmlands, and infrastructure and cause giant economic losses. Economic risk criteria are a kind of basis for determining dam risk levels and to decide whether ... ...

    Abstract When a dam breaks, huge floods will be generated that may inundate urban areas, enterprises, farmlands, and infrastructure and cause giant economic losses. Economic risk criteria are a kind of basis for determining dam risk levels and to decide whether risk control measures should be taken or not. However, compared to loss-of-life risk criteria, much fewer economic risk criteria for dams have been proposed and implemented for two main reasons: (a) The ability of most areas to endure economic losses caused by dam breach changes over time because of the constant development of their economic levels; and (b) Economic development levels in an area are distinct from the levels in other areas, resulting in significant differences in the ability of different areas to endure economic losses caused by a dam breach. Therefore, an equivalent economic scale (EES) that indicates the relative economic level of an area to the whole country in a given period of time is a preferred measure. It was shown in this paper that EES has much more stable values than do ordinary economic measures; therefore, it was taken as the basic index for establishing economic risk criteria. Furthermore, due to the distinct economic loss rates of different industries, the index of industrial economic contribution (IEC) was introduced to determine the correction coefficient to modify the ESS to reflect the potential economic loss of the area to be evaluated. This is the first research that pays careful attention to the change of ability to endure economic losses, in which the established economic risk criteria are applicable over a relatively long time and for different areas based on the consideration of the relative level of the economy and the industrial economic contribution.
    Keywords economic development ; financial economics ; floods ; risk reduction
    Language English
    Dates of publication 2020-0710
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2020.138139
    Database NAL-Catalogue (AGRICOLA)

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  8. Article ; Online: Vitamin D receptor

    Kang, Shaosan / Zhao, Yansheng / Wang, Lei / Liu, Jian / Chen, Xi / Liu, Xiaofeng / Shi, Zhijie / Gao, Weixing / Cao, Fenghong

    Oncotarget

    2018  Volume 9, Issue 6, Page(s) 7136–7147

    Abstract: Numerous previous studies reported the association of Vitamin D receptor ... ...

    Abstract Numerous previous studies reported the association of Vitamin D receptor gene
    Language English
    Publishing date 2018-01-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2560162-3
    ISSN 1949-2553 ; 1949-2553
    ISSN (online) 1949-2553
    ISSN 1949-2553
    DOI 10.18632/oncotarget.23606
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Lack of association between the risk of prostate cancer and vitamin D receptor

    Kang, Shaosan / Zhao, Yansheng / Wang, Lei / Liu, Jian / Chen, Xi / Liu, Xiaofeng / Shi, Zhijie / Gao, Weixing / Cao, Fenghong

    Cancer management and research

    2018  Volume 10, Page(s) 2377–2387

    Abstract: Background: The association between vitamin D receptor gene : Methods: All studies published up to December 2017 were identified via a systematic search of PubMed, Embase, and China National Knowledge Infrastructure databases. Pooled odds ratios (ORs) ...

    Abstract Background: The association between vitamin D receptor gene
    Methods: All studies published up to December 2017 were identified via a systematic search of PubMed, Embase, and China National Knowledge Infrastructure databases. Pooled odds ratios (ORs) with their 95% confidence intervals (CIs) were estimated to describe the strength of the relationship between
    Results: In this meta-analysis, 27 studies with 9,993 cases and 9,345 controls were included. The pooled results revealed that
    Conclusion: Our results suggest that
    Language English
    Publishing date 2018-08-01
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2508013-1
    ISSN 1179-1322
    ISSN 1179-1322
    DOI 10.2147/CMAR.S171305
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Bioinformatics analysis of differentially expressed proteins in prostate cancer based on proteomics data.

    Chen, Chen / Zhang, Li-Guo / Liu, Jian / Han, Hui / Chen, Ning / Yao, An-Liang / Kang, Shao-San / Gao, Wei-Xing / Shen, Hong / Zhang, Long-Jun / Li, Ya-Peng / Cao, Feng-Hong / Li, Zhi-Guo

    OncoTargets and therapy

    2016  Volume 9, Page(s) 1545–1557

    Abstract: We mined the literature for proteomics data to examine the occurrence and metastasis of prostate cancer (PCa) through a bioinformatics analysis. We divided the differentially expressed proteins (DEPs) into two groups: the group consisting of PCa and ... ...

    Abstract We mined the literature for proteomics data to examine the occurrence and metastasis of prostate cancer (PCa) through a bioinformatics analysis. We divided the differentially expressed proteins (DEPs) into two groups: the group consisting of PCa and benign tissues (P&b) and the group presenting both high and low PCa metastatic tendencies (H&L). In the P&b group, we found 320 DEPs, 20 of which were reported more than three times, and DES was the most commonly reported. Among these DEPs, the expression levels of FGG, GSN, SERPINC1, TPM1, and TUBB4B have not yet been correlated with PCa. In the H&L group, we identified 353 DEPs, 13 of which were reported more than three times. Among these DEPs, MDH2 and MYH9 have not yet been correlated with PCa metastasis. We further confirmed that DES was differentially expressed between 30 cancer and 30 benign tissues. In addition, DEPs associated with protein transport, regulation of actin cytoskeleton, and the extracellular matrix (ECM)-receptor interaction pathway were prevalent in the H&L group and have not yet been studied in detail in this context. Proteins related to homeostasis, the wound-healing response, focal adhesions, and the complement and coagulation pathways were overrepresented in both groups. Our findings suggest that the repeatedly reported DEPs in the two groups may function as potential biomarkers for detecting PCa and predicting its aggressiveness. Furthermore, the implicated biological processes and signaling pathways may help elucidate the molecular mechanisms of PCa carcinogenesis and metastasis and provide new targets for clinical treatment.
    Language English
    Publishing date 2016-03-16
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2495130-4
    ISSN 1178-6930
    ISSN 1178-6930
    DOI 10.2147/OTT.S98807
    Database MEDical Literature Analysis and Retrieval System OnLINE

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