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  1. Article ; Online: Clinical characteristics and outcomes of pleural aspergillosis: a review of 13 cases.

    Zhang, Jing / Gao, Xing-Lin / Wu, Jian / Chen, Jing-Jing

    Microbiology spectrum

    2024  Volume 12, Issue 4, Page(s) e0385223

    Abstract: Aspergillus pleurisy is a rare complication of invasive pulmonary aspergillosis (IPA), which mostly occurs in the immunocompromised host. The clinical condition is critical, especially to those who develop bronchopleural fistula. This study aimed to ... ...

    Abstract Aspergillus pleurisy is a rare complication of invasive pulmonary aspergillosis (IPA), which mostly occurs in the immunocompromised host. The clinical condition is critical, especially to those who develop bronchopleural fistula. This study aimed to assess the characteristics and the prognosis of aspergillus pleurisy. Clinical data from 13 patients diagnosed with aspergillus pleurisy in our hospital from January 2000 to December 2022 were retrospectively studied. Thirteen patients with
    Importance: Aspergillus pleurisy is a rare complication of invasive pulmonary aspergillosis (IPA), associated with a poor prognosis. The morbidity and mortality of this condition have not been thoroughly studied, and recent research on this topic is limited. The current study included 13 patients diagnosed with Aspergillus pleurisy, with the majority presenting concomitantly with a bronchopleural fistula. Among these patients, nine had a history of thoracic surgery, including lung transplantation and lobectomy. Four patients refused further treatment and were discharged against medical advice, while one patient succumbed to massive hemoptysis 2 years after discharge. This case series provides essential insights into Aspergillus pleurisy and evaluates the therapeutic strategy based on a limited cohort.
    MeSH term(s) Male ; Female ; Humans ; Adolescent ; Young Adult ; Adult ; Middle Aged ; Aged ; Invasive Pulmonary Aspergillosis/drug therapy ; Antifungal Agents/therapeutic use ; Hemoptysis/drug therapy ; Retrospective Studies ; Aspergillus ; Pleurisy/drug therapy ; Fistula/drug therapy
    Chemical Substances Antifungal Agents
    Language English
    Publishing date 2024-02-27
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 2807133-5
    ISSN 2165-0497 ; 2165-0497
    ISSN (online) 2165-0497
    ISSN 2165-0497
    DOI 10.1128/spectrum.03852-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: [Research status of solid tumor immunity regulated by DNA methylation].

    Li, S S / Gao, X L

    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases

    2021  Volume 44, Issue 10, Page(s) 921–926

    MeSH term(s) Cell Line, Tumor ; DNA Methylation ; Gene Expression Regulation, Neoplastic
    Language Chinese
    Publishing date 2021-09-26
    Publishing country China
    Document type Journal Article
    ZDB-ID 1027965-9
    ISSN 1001-0939
    ISSN 1001-0939
    DOI 10.3760/cma.j.cn112147-20201116-01098
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    In stock of ZB MED Cologne/Königswinter

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  3. Article: [Sedentary behavior, screen time and mental health of college students: a Meta-analysis].

    Gao, X L / Zhang, J H / Yang, Y / Cao, Z B

    Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi

    2023  Volume 44, Issue 3, Page(s) 477–485

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Humans ; Mental Health ; Depression/diagnosis ; Sedentary Behavior ; Screen Time ; Students/psychology
    Language Chinese
    Publishing date 2023-03-11
    Publishing country China
    Document type Meta-Analysis ; English Abstract ; Journal Article
    ZDB-ID 645026-x
    ISSN 0254-6450
    ISSN 0254-6450
    DOI 10.3760/cma.j.cn112338-20220728-00669
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    In stock of ZB MED Cologne/Königswinter

    Zs.B 3276: Show issues Location:
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  4. Article: [Research progress in coagulation dysfunction and its relationship with cytokine storm syndrome in patients with severe/critical COVID-19].

    Zhang, J / Gao, X L / Yang, L H

    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi

    2021  Volume 42, Issue 8, Page(s) 700–704

    MeSH term(s) Blood Coagulation ; Blood Coagulation Disorders ; COVID-19 ; Cytokine Release Syndrome ; Cytokines ; Humans ; SARS-CoV-2
    Chemical Substances Cytokines
    Language Chinese
    Publishing date 2021-09-14
    Publishing country China
    Document type Journal Article
    ZDB-ID 2997162-7
    ISSN 0253-2727 ; 0253-2727
    ISSN (online) 0253-2727
    ISSN 0253-2727
    DOI 10.3760/cma.j.issn.0253-2727.2021.08.019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: [Clinical characteristics of 111 cases with mucopolysaccharidosis ⅣA].

    Yi, M N / Zhang, H W / Gao, X L / Wang, Y / Han, L S / Qiu, W J / Gu, X F

    Zhonghua er ke za zhi = Chinese journal of pediatrics

    2023  Volume 61, Issue 6, Page(s) 503–508

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Male ; Child ; Female ; Humans ; Adolescent ; Mucopolysaccharidosis IV ; Pectus Carinatum ; Retrospective Studies ; Snoring ; China ; Mucopolysaccharidoses ; Growth Disorders ; Vision Disorders
    Language Chinese
    Publishing date 2023-06-14
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 784523-6
    ISSN 0578-1310
    ISSN 0578-1310
    DOI 10.3760/cma.j.cn112140-20230308-00170
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 3292: Show issues Location:
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  6. Article: A non-classical Mindlin plate model incorporating microstructure, surface energy and foundation effects.

    Gao, X-L / Zhang, G Y

    Proceedings. Mathematical, physical, and engineering sciences

    2016  Volume 472, Issue 2191, Page(s) 20160275

    Abstract: A non-classical model for a Mindlin plate resting on an elastic foundation is developed in a general form using a modified couple stress theory, a surface elasticity theory and a two-parameter Winkler-Pasternak foundation model. It includes all five ... ...

    Abstract A non-classical model for a Mindlin plate resting on an elastic foundation is developed in a general form using a modified couple stress theory, a surface elasticity theory and a two-parameter Winkler-Pasternak foundation model. It includes all five kinematic variables possible for a Mindlin plate. The equations of motion and the complete boundary conditions are obtained simultaneously through a variational formulation based on Hamilton's principle, and the microstructure, surface energy and foundation effects are treated in a unified manner. The newly developed model contains one material length-scale parameter to describe the microstructure effect, three surface elastic constants to account for the surface energy effect, and two foundation parameters to capture the foundation effect. The current non-classical plate model reduces to its classical elasticity-based counterpart when the microstructure, surface energy and foundation effects are all suppressed. In addition, the new model includes the Mindlin plate models considering the microstructure dependence or the surface energy effect or the foundation influence alone as special cases, recovers the Kirchhoff plate model incorporating the microstructure, surface energy and foundation effects, and degenerates to the Timoshenko beam model including the microstructure effect. To illustrate the new Mindlin plate model, the static bending and free vibration problems of a simply supported rectangular plate are analytically solved by directly applying the general formulae derived.
    Language English
    Publishing date 2016-08-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 209241-4
    ISSN 1471-2946 ; 1364-5021 ; 0962-8444 ; 0080-4630 ; 0950-1207
    ISSN (online) 1471-2946
    ISSN 1364-5021 ; 0962-8444 ; 0080-4630 ; 0950-1207
    DOI 10.1098/rspa.2016.0275
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Mechanism of MIR-210 mediated NF-κB pathway on cardiac ischemia-reperfusion injury.

    Liu, L / Wang, F E / Feng, Q / Mi, X F / Zhao, J J / Gao, X L

    Journal of biological regulators and homeostatic agents

    2021  Volume 35, Issue Special Issue on Internal Medicine n.1

    Abstract: In this study, MicroRNA-210 (miR-210), which was previously proved to be a potential immunomodulator in various disease, attenuated mouse myocardium ischemia/reperfusion (I/R) injury. miR-210 was increased in cardiomyocytes exposed to hypoxia/ ... ...

    Abstract In this study, MicroRNA-210 (miR-210), which was previously proved to be a potential immunomodulator in various disease, attenuated mouse myocardium ischemia/reperfusion (I/R) injury. miR-210 was increased in cardiomyocytes exposed to hypoxia/reoxygenation (H/R). The expression of IL-6 and TNF-α in both serum and supernatant were reduced in miR-210 mimics groups. Mice were randomly divided into four groups, which were pre-treated with saline (sham and ischemia/reperfusion group), miR-210 mimics and miR-210 inhibitor treatments. Three days later, the mouse IR model was established by ischemia for 30 min, followed by reperfusion for 3 h. Myocardium and plasma were harvested and assessed. The myocardium histopathological changes were reduced in miR-210 mimics groups, and serum levels of Creatine kinase isoenzyme (CK-MB) and Lactate dehydrogenase (LDH) were significantly decreased compared with I/R groups. The protein expression of proinflammatory factor interleukin (IL)-1β and IL-6 were suppressed by the up-regulation of miR-210. The expression of miR-210 was negatively correlated with the expression of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB). In conclusion, our study indicates that miR-210 protects heart from myocardium I/R injury via suppressing NF-κB signal pathway.
    MeSH term(s) Animals ; Mice ; MicroRNAs/genetics ; Myocardial Reperfusion Injury/genetics ; Myocytes, Cardiac ; NF-kappa B/genetics ; Rats ; Rats, Sprague-Dawley ; Reperfusion Injury
    Chemical Substances MIRN210 microRNA, mouse ; MIRN210 microRNA, rat ; MicroRNAs ; NF-kappa B
    Language English
    Publishing date 2021-07-30
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 639196-5
    ISSN 1724-6083 ; 0393-974X
    ISSN (online) 1724-6083
    ISSN 0393-974X
    DOI 10.23812/21-SI1-7
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    In stock of ZB MED Cologne/Königswinter

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  8. Article: [The progress and controversy of atrial septal occluder in the treatment of bronchopleural fistula].

    Zhong, Z C / Chen, J J / Gao, X L

    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases

    2018  Volume 41, Issue 6, Page(s) 491–493

    Language Chinese
    Publishing date 2018-07-06
    Publishing country China
    Document type Journal Article
    ZDB-ID 1027965-9
    ISSN 1001-0939
    ISSN 1001-0939
    DOI 10.3760/cma.j.issn.1001-0939.2018.06.011
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  9. Article: [Predictive value of prognostic inflammatory and tumor score in intrahepatic cholangiocarcinoma].

    Ma, B Q / Meng, H J / Dong, X F / Gao, X L / Wu, Y N / Zhang, W / Li, S P / Shen, A

    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology

    2022  Volume 30, Issue 7, Page(s) 777–783

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Bile Duct Neoplasms/diagnosis ; Bile Duct Neoplasms/pathology ; Bile Ducts, Intrahepatic/pathology ; Biomarkers, Tumor ; CA-19-9 Antigen ; Cholangiocarcinoma/diagnosis ; Cholangiocarcinoma/pathology ; Humans ; Prognosis ; Retrospective Studies
    Chemical Substances Biomarkers, Tumor ; CA-19-9 Antigen
    Language Chinese
    Publishing date 2022-06-03
    Publishing country China
    Document type Journal Article
    ISSN 1007-3418
    ISSN 1007-3418
    DOI 10.3760/cma.j.cn501113-20211108-00539
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Mir-98 reduces the expression of HMGA2 and promotes osteogenic differentiation of mesenchymal stem cells.

    Gao, X-L / Cao, M-G / Ai, G-G / Hu, Y-B

    European review for medical and pharmacological sciences

    2018  Volume 22, Issue 11, Page(s) 3311–3317

    Abstract: Objective: To study effects of microRNA-98 (miR-98) on osteogenic differentiation of mesenchymal stem cells (MSCs).: Patients and methods: We predicted target gene of miR-98 with software test, and detected expression changes of miR-98, as well as ... ...

    Abstract Objective: To study effects of microRNA-98 (miR-98) on osteogenic differentiation of mesenchymal stem cells (MSCs).
    Patients and methods: We predicted target gene of miR-98 with software test, and detected expression changes of miR-98, as well as its target gene HMGA2, in the process of osteogenic differentiation of mesenchymal stem cells. After transfection of miR-98 mimic and HMGA2 siRNA, we induced osteogenic differentiation and detected expression changes of osteogenic differentiation markers (RUNX2, ALP, OCN, and BSP).
    Results: MiR-98 combined directly with target gene HMGA2 and inhibited its expression. During the process of osteogenic differentiation, expression of miR-98 was up-regulated, while HMGA2 expression was down-regulated. In addition, the expression of osteogenesis maker genes increased in cells being transfected with miR-98 mimics and HMGA2 siRNA.
    Conclusions: MiR-98 can promote osteogenic differentiation of mesenchymal stem cells by targeting gene HMGA2.
    MeSH term(s) Cell Differentiation/genetics ; Cells, Cultured ; Down-Regulation ; Gene Expression Regulation ; HMGA2 Protein/genetics ; Humans ; Mesenchymal Stem Cells/cytology ; Mesenchymal Stem Cells/metabolism ; MicroRNAs/genetics ; Osteogenesis/genetics ; RNA, Small Interfering/genetics ; Transfection ; Up-Regulation
    Chemical Substances HMGA2 Protein ; HMGA2 protein, human ; MIRN98 microRNA, human ; MicroRNAs ; RNA, Small Interfering
    Language English
    Publishing date 2018-06-19
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 605550-3
    ISSN 2284-0729 ; 1128-3602 ; 0392-291X
    ISSN (online) 2284-0729
    ISSN 1128-3602 ; 0392-291X
    DOI 10.26355/eurrev_201806_15150
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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