LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 209

Search options

  1. Article ; Online: Secondary metabolites from a deep-sea derived fungal strain of Phomopsis lithocarpus FS508 [Correction: Aug. 2023, 37(15), p. 2638]

    Hu, Jinhua / Wang, Nuoyi / Liu, Hongxin / Li, Saini / Liu, Zhaoming / Zhang, Weimin / Gao, Xiaoxia

    Natural Product Research. 2023 July 18, v. 37, no. 14, p. 2351-2358

    2023  , Page(s) 2351–2358

    Abstract: One new isoindolinone lactam lithocarlactam A (1) and one new triterpene lithocarin D (2), along with nine known natural products (3-11) were isolated from the broth extract of marine fungus Phomopsis lithocarpus FS508, which was isolated from a deep-sea ...

    Abstract One new isoindolinone lactam lithocarlactam A (1) and one new triterpene lithocarin D (2), along with nine known natural products (3-11) were isolated from the broth extract of marine fungus Phomopsis lithocarpus FS508, which was isolated from a deep-sea sediment sample. Their structures were elucidated by interpretation of spectroscopic analysis and comparison with previously published literatures for the known compounds. Moreover, compounds 1 and 2 were evaluated for cytotoxic activity against SF-268, MCF-7, HepG-2, and A549 cell lines. However, both of them showed no activity against the tumor cell lines.
    Keywords Diaporthe ; cytotoxicity ; lactams ; marine fungi ; marine sediments ; neoplasm cells ; research ; secondary metabolites ; spectral analysis ; triterpenoids ; Marine fungus ; Phomopsis lithocarpus ; isoindolinone lactam
    Language English
    Dates of publication 2023-0718
    Size p. 2351-2358
    Publishing place Taylor & Francis
    Document type Article ; Online
    ZDB-ID 2185747-7
    ISSN 1478-6427 ; 1478-6419
    ISSN (online) 1478-6427
    ISSN 1478-6419
    DOI 10.1080/14786419.2022.2044810
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article: Effects of different drying methods on chemical compositions, antioxidant activity and anti-

    Miao, Jing / Liu, Jingjing / Gao, Xiaoxia / Lu, Fangyi / Yang, Xue

    Heliyon

    2022  Volume 8, Issue 11, Page(s) e11784

    Abstract: Coreopsis ... ...

    Abstract Coreopsis tinctoria
    Language English
    Publishing date 2022-11-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2022.e11784
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: Research on Deep Learning Method and Optimization of Vibration Characteristics of Rotating Equipment.

    Zhu, Xiaoxun / Liu, Baoping / Li, Zhentao / Lin, Jiawei / Gao, Xiaoxia

    Sensors (Basel, Switzerland)

    2022  Volume 22, Issue 10

    Abstract: CNN extracts the signal characteristics layer by layer through the local perception of convolution kernel, but the rotation speed and sampling frequency of the vibration signal of rotating equipment are not the same. Extracting different signal features ... ...

    Abstract CNN extracts the signal characteristics layer by layer through the local perception of convolution kernel, but the rotation speed and sampling frequency of the vibration signal of rotating equipment are not the same. Extracting different signal features with a fixed convolution kernel will affect the local feature perception and ultimately affect the learning effect and recognition accuracy. In order to solve this problem, the matching between the size of convolution kernel and the signal (rotation speed, sampling frequency) was optimized with the matching relation obtained. Through the study of this paper, the ability of extracting vibration features of CNN was improved, and the accuracy of vibration state recognition was finally improved to 98%.
    MeSH term(s) Algorithms ; Deep Learning ; Neural Networks, Computer ; Vibration
    Language English
    Publishing date 2022-05-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s22103693
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article: DNA barcoding: an efficient technology to authenticate plant species of traditional Chinese medicine and recent advances.

    Zhu, Shuang / Liu, Qiaozhen / Qiu, Simin / Dai, Jiangpeng / Gao, Xiaoxia

    Chinese medicine

    2022  Volume 17, Issue 1, Page(s) 112

    Abstract: Traditional Chinese medicine (TCM) plays an important role in the global traditional health systems. However, adulterated and counterfeit TCM is on the rise. DNA barcoding is an effective, rapid, and accurate technique for identifying plant species. In ... ...

    Abstract Traditional Chinese medicine (TCM) plays an important role in the global traditional health systems. However, adulterated and counterfeit TCM is on the rise. DNA barcoding is an effective, rapid, and accurate technique for identifying plant species. In this study, we collected manuscripts on DNA barcoding published in the last decade and summarized the use of this technique in identifying 50 common Chinese herbs listed in the Chinese pharmacopoeia. Based on the dataset of the major seven DNA barcodes of plants in the NCBI database, the strengths and limitations of the barcodes and their derivative barcoding technology, including single-locus barcode, multi-locus barcoding, super-barcoding, meta-barcoding, and mini-barcoding, were illustrated. In addition, the advances in DNA barcoding, particularly identifying plant species for TCM using machine learning technology, are also reviewed. Finally, the selection process of an ideal DNA barcoding technique for accurate identification of a given TCM plant species was also outlined.
    Language English
    Publishing date 2022-09-28
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2260322-0
    ISSN 1749-8546
    ISSN 1749-8546
    DOI 10.1186/s13020-022-00655-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: The effect of diet quality on the risk of developing gestational diabetes mellitus: A systematic review and meta-analysis.

    Gao, Xiaoxia / Zheng, Qingxiang / Jiang, Xiumin / Chen, Xiaoqian / Liao, Yanping / Pan, Yuqing

    Frontiers in public health

    2023  Volume 10, Page(s) 1062304

    Abstract: Objective: To examine the effect of diet quality on the risk of gestational diabetes mellitus.: Methods: This review included cohort and case-control studies reporting an association between diet quality and gestational diabetes mellitus. We searched ...

    Abstract Objective: To examine the effect of diet quality on the risk of gestational diabetes mellitus.
    Methods: This review included cohort and case-control studies reporting an association between diet quality and gestational diabetes mellitus. We searched PubMed, Cochrane Library, Web of Science, Embase, PsycINFO, CINAHL Complete, Chinese Periodical Full-text Database, China National Knowledge Infrastructure, Chinese Biomedical Literature Database, and China Wanfang Database for studies published from inception to November 18, 2022. The Newcastle-Ottawa Scale was used for quality assessment, and the overall quality of evidence was assessed using the GRADEpro GDT.
    Results: A total of 19 studies (15 cohort, four case-control) with 108,084 participants were included. We found that better higher diet quality before or during pregnancy reduced the risk of developing gestational diabetes mellitus, including a higher Mediterranean diet (OR: 0.51; 95% CI: 0.30-0.86), dietary approaches to stop hypertension (OR: 0.66; 95% CI: 0.44-0.97), Alternate Healthy Eating Index (OR: 0.61; 95% CI: 0.44-0.83), overall plant-based diet index (OR: 0.57; 95% CI: 0.41-0.78), and adherence to national dietary guidelines (OR: 0.39; 95% CI:0.31-0.48). However, poorer diet quality increased the risk of gestational diabetes mellitus, including a higher dietary inflammatory index (OR: 1.37; 95% CI: 1.21-1.57) and overall low-carbohydrate diets (OR: 1.41; 95% CI: 1.22-1.64). After meta-regression, subgroup, and sensitivity analyses, the results remained statistically significant.
    Conclusions: Before and during pregnancy, higher diet quality reduced the risk of developing gestational diabetes mellitus, whereas poorer diet quality increased this risk.
    Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/, identifier: CRD42022372488.
    MeSH term(s) Pregnancy ; Female ; Humans ; Diabetes, Gestational/epidemiology ; Diabetes, Gestational/etiology ; Diet, Healthy ; Hypertension ; Diet, Mediterranean ; China/epidemiology
    Language English
    Publishing date 2023-01-09
    Publishing country Switzerland
    Document type Meta-Analysis ; Systematic Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2022.1062304
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: Correction: Gong et al. Neuroprotective and Cytotoxic Phthalides from

    Gong, Wenxia / Zhou, Yuzhi / Li, Xiao / Gao, Xiaoxia / Tian, Junsheng / Qin, Xuemei / Du, Guanhua

    Molecules (Basel, Switzerland)

    2023  Volume 28, Issue 23

    Abstract: ... Error in ... ...

    Abstract Error in Figure
    Language English
    Publishing date 2023-11-28
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules28237814
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.MO 81: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article: Comparative and phylogenetic analysis of the complete chloroplast genomes of

    Dai, Jiangpeng / Liu, Qiaozhen / Xu, Xingyuan / Tan, Zhijie / Lin, Yuexia / Gao, Xiaoxia / Zhu, Shuang

    Frontiers in plant science

    2023  Volume 14, Page(s) 1271689

    Abstract: ... The ... ...

    Abstract The genus
    Language English
    Publishing date 2023-12-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2613694-6
    ISSN 1664-462X
    ISSN 1664-462X
    DOI 10.3389/fpls.2023.1271689
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: Cytospotones A-D, four new polyketones from the endophytic fungus Cytospora sp. A879.

    Ma, Weipeng / Shao, Zhishen / Chen, Yuchan / Li, Saini / Liu, Hongxin / Zhang, Weimin / Gao, Xiaoxia

    Fitoterapia

    2023  Volume 173, Page(s) 105751

    Abstract: Three new α-pyrone derivatives cytospotones A-C (1-3) and a new cyclohexenone derivative cytospotone D (4) together with four known α-pyrones were isolated from the endophytic fungus Cytospora sp. A879 of Pogostemon cablin (Blanco) Benth. The structures ... ...

    Abstract Three new α-pyrone derivatives cytospotones A-C (1-3) and a new cyclohexenone derivative cytospotone D (4) together with four known α-pyrones were isolated from the endophytic fungus Cytospora sp. A879 of Pogostemon cablin (Blanco) Benth. The structures of 1-4 were elucidated primarily by spectroscopic methods (1D, 2D NMR and HRESIMS), ECD spectra analyses, and ECD calculations. Furthermore, the four new compounds (1-4) were evaluated for their anti-inflammatory and α-glucosidase inhibitory activities. The results showed that compound 1 had moderate inhibitory effect on LPS-induced NO production in RAW 264.7 macrophages.
    MeSH term(s) Molecular Structure ; Ascomycota/chemistry ; Pogostemon ; Magnetic Resonance Spectroscopy ; Pyrones
    Chemical Substances Pyrones
    Language English
    Publishing date 2023-11-17
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 412385-2
    ISSN 1873-6971 ; 0367-326X
    ISSN (online) 1873-6971
    ISSN 0367-326X
    DOI 10.1016/j.fitote.2023.105751
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 1873: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: Radix Paeoniae Alba attenuates Radix Bupleuri-induced hepatotoxicity by modulating gut microbiota to alleviate the inhibition of saikosaponins on glutathione synthetase.

    Chen, Congcong / Gong, Wenxia / Tian, Junshen / Gao, Xiaoxia / Qin, Xuemei / Du, Guanhua / Zhou, Yuzhi

    Journal of pharmaceutical analysis

    2023  Volume 13, Issue 6, Page(s) 640–659

    Abstract: Radix Bupleuri (RB) is commonly used to treat depression, but it can also lead to hepatotoxicity after long-term use. In many anti-depression prescriptions, RB is often used in combination with Radix Paeoniae Alba (RPA) as an herb pair. However, whether ... ...

    Abstract Radix Bupleuri (RB) is commonly used to treat depression, but it can also lead to hepatotoxicity after long-term use. In many anti-depression prescriptions, RB is often used in combination with Radix Paeoniae Alba (RPA) as an herb pair. However, whether RPA can alleviate RB-induced hepatotoxicity remain unclear. In this work, the results confirmed that RB had a dose-dependent antidepressant effect, but the optimal antidepressant dose caused hepatotoxicity. Notably, RPA effectively reversed RB-induced hepatotoxicity. Afterward, the mechanism of RB-induced hepatotoxicity was confirmed. The results showed that saikosaponin A and saikosaponin D could inhibit GSH synthase (GSS) activity in the liver, and further cause liver injury through oxidative stress and nuclear factor kappa B (NF-κB)/NOD-like receptor thermal protein domain associated protein 3 (NLRP3) pathway. Furthermore, the mechanisms by which RPA attenuates RB-induced hepatotoxicity were investigated. The results demonstrated that RPA increased the abundance of intestinal bacteria with glycosidase activity, thereby promoting the conversion of saikosaponins to saikogenins in vivo. Different from saikosaponin A and saikosaponin D, which are directly combined with GSS as an inhibitor, their deglycosylation conversion products saikogenin F and saikogenin G exhibited no GSS binding activity. Based on this, RPA can alleviate the inhibitory effect of saikosaponins on GSS activity to reshape the liver redox balance and further reverse the RB-induced liver inflammatory response by the NF-κB/NLRP3 pathway. In conclusion, the present study suggests that promoting the conversion of saikosaponins by modulating gut microbiota to attenuate the inhibition of GSS is the potential mechanism by which RPA prevents RB-induced hepatotoxicity.
    Language English
    Publishing date 2023-04-26
    Publishing country China
    Document type Journal Article
    ZDB-ID 2630174-X
    ISSN 2214-0883 ; 2095-1779
    ISSN (online) 2214-0883
    ISSN 2095-1779
    DOI 10.1016/j.jpha.2023.04.016
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: Saikosaponins regulate bile acid excretion in mice liver and ileum by activating farnesoid X receptor and bile acid transporter.

    Wang, YuKun / Li, Jing / Wu, Li / Qin, XueMei / Xie, Cen / Gao, XiaoXia

    Phytotherapy research : PTR

    2023  Volume 37, Issue 10, Page(s) 4572–4586

    Abstract: Radix Bupleuri exerts effective hepatoprotective and cholagogic effects through its Saikosaponins (SSs) component. Therefore, we attempted to determine the mechanism of saikosaponins used to promote bile excretion by studying their effects on ... ...

    Abstract Radix Bupleuri exerts effective hepatoprotective and cholagogic effects through its Saikosaponins (SSs) component. Therefore, we attempted to determine the mechanism of saikosaponins used to promote bile excretion by studying their effects on intrahepatic bile flow, focusing on the synthesis, transport, excretion, and metabolism of bile acids. C57BL/6N mice were continuously gavaged with saikosaponin a (SSa), saikosaponin b
    Language English
    Publishing date 2023-06-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 639136-9
    ISSN 1099-1573 ; 0951-418X
    ISSN (online) 1099-1573
    ISSN 0951-418X
    DOI 10.1002/ptr.7927
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 3092: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top