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  1. Article ; Online: Study on the adsorption of Zn(II) and Cu(II) in acid mine drainage by fly ash loaded nano-FeS.

    Guo, Xuying / Fu, Honglei / Gao, Xinle / Zhao, Zilong / Hu, Zhiyong

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 9927

    Abstract: Aiming at the acid mine drainage (AMD) in zinc, copper and other heavy metals treatment difficulties, severe pollution of soil and water environment and other problems. Through the ultrasonic precipitation method, this study prepared fly ash-loaded nano- ... ...

    Abstract Aiming at the acid mine drainage (AMD) in zinc, copper and other heavy metals treatment difficulties, severe pollution of soil and water environment and other problems. Through the ultrasonic precipitation method, this study prepared fly ash-loaded nano-FeS composites (nFeS-F). The effects of nFeS-F dosage, pH, stirring rate, reaction time and initial concentration of the solution on the adsorption of Zn(II) and Cu(II) were investigated. The data were fitted by Lagergren first and second-order kinetic equations, Internal diffusion equation, Langmuir and Freundlich isotherm models, and combined with SEM, TEM, FTIR, TGA, and XPS assays to reveal the mechanism of nFeS-F adsorption of Zn(II) and Cu(II). The results demonstrated that: The removal of Zn(II) and Cu(II) by nFeS-F could reach 83.36% and 70.40%, respectively (The dosage was 8 g/L, pH was 4, time was 150 min, and concentration was 100 mg/L). The adsorption process, mainly chemical adsorption, conforms to the Lagergren second-order kinetic equation (R
    Language English
    Publishing date 2024-04-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-58815-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Study on the Preparation of Nano-FeS Loaded on Fly Ash and Its Cr Removal Performance.

    Guo, Xuying / Hu, Zhiyong / Gao, Xinle / Dong, Yanrong / Fu, Saiou

    ACS omega

    2022  Volume 7, Issue 36, Page(s) 32331–32338

    Abstract: Chromium has been considered as one of the most hazardous heavy metals because of its strong and persistent toxicity to the ecosystem and human beings. In this study, fly ash-loaded nano-FeS (nFeS-F) composites were constructed with fly ash as the ... ...

    Abstract Chromium has been considered as one of the most hazardous heavy metals because of its strong and persistent toxicity to the ecosystem and human beings. In this study, fly ash-loaded nano-FeS (nFeS-F) composites were constructed with fly ash as the carrier, and the performance and mechanism of the composites for the removal of Cr(VI) and total chromium from water were investigated. The composite was characterized by X-ray diffraction and transmission electron microscopy. The effects of fly ash size, molarity of FeSO
    Language English
    Publishing date 2022-09-02
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.2c03699
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Dynamic experiment on the treatment of acidic chromium-containing wastewater by lignite loaded nano FeS

    Guo, Xuying / Gao, Xinle / Fu, Saiou / Jiang, Guoliang / Dong, Yanrong / Hu, Zhiyong

    RSC advances. 2022 Feb. 18, v. 12, no. 10

    2022  

    Abstract: In terms of the problem of severe pollution to the ecological environment caused by the acidic chrome-containing wastewater produced in the tanning, electroplating, metallurgy, printing and dyeing and other industries, based on the good adsorbability, ... ...

    Abstract In terms of the problem of severe pollution to the ecological environment caused by the acidic chrome-containing wastewater produced in the tanning, electroplating, metallurgy, printing and dyeing and other industries, based on the good adsorbability, reducibility and other properties of heavy metals such as Cr(vi) by lignite and nano FeS, the lignite-loaded nano FeS adsorbing material (nFeS-lignite) was prepared by ultrasonic precipitation method. NFeS-lignite and lignite were used as fillers to construct 1# and 2# dynamic columns to carry out the dynamic treatment experiment of acidic chrome-containing wastewater. And nFeS-lignite and lignite were characterized by XRD, SEM and EDS to explore the regularity, long-acting properties and removal mechanism of acidic chrome-containing wastewater treated by NFeS-lignite and lignite. The results indicate that: ① during 25 days of operation, the average removal percentages of Cr(vi) in the 1# and 2# dynamic columns are 71.6% and 53.1%. The average removal percentages of total chromium in 1# and 2# dynamic columns are 54.4% and 28.8%, and the average effluent pH of 1# and 2# dynamic columns is 5.3 and 7.3. ② According to XRD, SEM, EDS and FTIR analysis, the reducing groups in the structure of nFeS-lignite, such as –CH₃, –CH₂, C–O and Ar-OH, participate in the reaction and are oxidized to CC, CO and other groups. A large number of sediment crystals appeared on the particle surface, and new diffraction peaks such as FeOOH, Cr(OH)₃ and Cr₂S₃ appeared at the same time, indicating that after Cr(vi) was reduced to Cr(iii), it would be fixed on the surface of nFeS-lignite in the form of precipitation such as hydroxide and sulfide.
    Keywords chromium ; lignite ; metallurgy ; pH ; pollution ; sediments ; sulfides ; ultrasonics ; wastewater
    Language English
    Dates of publication 2022-0218
    Size p. 6054-6062.
    Publishing place The Royal Society of Chemistry
    Document type Article
    ISSN 2046-2069
    DOI 10.1039/d1ra08892k
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: Dynamic experiment on the treatment of acidic chromium-containing wastewater by lignite loaded nano FeS.

    Guo, Xuying / Gao, Xinle / Fu, Saiou / Jiang, Guoliang / Dong, Yanrong / Hu, Zhiyong

    RSC advances

    2022  Volume 12, Issue 10, Page(s) 6054–6062

    Abstract: In terms of the problem of severe pollution to the ecological environment caused by the acidic chrome-containing wastewater produced in the tanning, electroplating, metallurgy, printing and dyeing and other industries, based on the good adsorbability, ... ...

    Abstract In terms of the problem of severe pollution to the ecological environment caused by the acidic chrome-containing wastewater produced in the tanning, electroplating, metallurgy, printing and dyeing and other industries, based on the good adsorbability, reducibility and other properties of heavy metals such as Cr(vi) by lignite and nano FeS, the lignite-loaded nano FeS adsorbing material (nFeS-lignite) was prepared by ultrasonic precipitation method. NFeS-lignite and lignite were used as fillers to construct 1# and 2# dynamic columns to carry out the dynamic treatment experiment of acidic chrome-containing wastewater. And nFeS-lignite and lignite were characterized by XRD, SEM and EDS to explore the regularity, long-acting properties and removal mechanism of acidic chrome-containing wastewater treated by NFeS-lignite and lignite. The results indicate that: ① during 25 days of operation, the average removal percentages of Cr(vi) in the 1# and 2# dynamic columns are 71.6% and 53.1%. The average removal percentages of total chromium in 1# and 2# dynamic columns are 54.4% and 28.8%, and the average effluent pH of 1# and 2# dynamic columns is 5.3 and 7.3. ② According to XRD, SEM, EDS and FTIR analysis, the reducing groups in the structure of nFeS-lignite, such as -CH
    Language English
    Publishing date 2022-02-18
    Publishing country England
    Document type Journal Article
    ISSN 2046-2069
    ISSN (online) 2046-2069
    DOI 10.1039/d1ra08892k
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Study on Growth Influencing Factors and Desulfurization Performance of

    Dong, Yanrong / Wang, Jingbo / Gao, Ziqing / Di, Junzhen / Wang, Dong / Guo, Xuying / Hu, Zhiyong / Gao, Xinle / Wang, Yunfeng

    ACS omega

    2023  Volume 8, Issue 4, Page(s) 4046–4059

    Abstract: Sulfate reducing ... ...

    Abstract Sulfate reducing bacteria
    Language English
    Publishing date 2023-01-20
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.2c06931
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Semiautomated design and soluble expression of a chimeric antigen TbpAB01 from Glaesserella parasuis.

    Chen, Jin-Ping / Zhou, Lin / Gong, Jin-Song / Wang, Nan-Kai / Miao, Fen-Fang / Su, Chang / Gao, Xin-Le / Xu, Guo-Qiang / Shi, Jin-Song / Xu, Zheng-Hong

    Biotechnology and bioengineering

    2024  

    Abstract: Pathogenic bacterial membrane proteins (MPs) are a class of vaccine and antibiotic development targets with widespread clinical application. However, the inherent hydrophobicity of MPs poses a challenge to fold correctly in living cells. Herein, we ... ...

    Abstract Pathogenic bacterial membrane proteins (MPs) are a class of vaccine and antibiotic development targets with widespread clinical application. However, the inherent hydrophobicity of MPs poses a challenge to fold correctly in living cells. Herein, we present a comprehensive method to improve the soluble form of MP antigen by rationally designing multi-epitope chimeric antigen (ChA) and screening two classes of protein-assisting folding element. The study uses a homologous protein antigen as a functional scaffold to generate a ChA possessing four epitopes from transferrin-binding protein A of Glaesserella parasuis. Our engineered strain, which co-expresses P17 tagged-ChA and endogenous chaperones groEL-ES, yields a 0.346 g/L highly soluble ChA with the property of HPS-positive serum reaction. Moreover, the protein titer of ChA reaches 4.27 g/L with >90% soluble proportion in 5-L bioreactor, which is the highest titer reported so far. The results highlight a timely approach to design and improve the soluble expression of MP antigen in industrially viable applications.
    Language English
    Publishing date 2024-04-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 280318-5
    ISSN 1097-0290 ; 0006-3592
    ISSN (online) 1097-0290
    ISSN 0006-3592
    DOI 10.1002/bit.28710
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 960: Show issues Location:
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  7. Article ; Online: Significantly enhanced tumor cellular and lysosomal hydroxychloroquine delivery by smart liposomes for optimal autophagy inhibition and improved antitumor efficiency with liposomal doxorubicin.

    Wang, Yang / Shi, Kairong / Zhang, Li / Hu, Guanlian / Wan, Jingyu / Tang, Jiajing / Yin, Sheng / Duan, Jiandong / Qin, Ming / Wang, Neng / Xie, Dandan / Gao, Xinle / Gao, Huile / Zhang, Zhirong / He, Qin

    Autophagy

    2016  Volume 12, Issue 6, Page(s) 949–962

    Abstract: Hydroxychloroquine (HCQ) inhibits autophagy and therefore can sensitize some cancer cells to chemotherapy, but the high doses required limit its clinical use. Here we show that loading HCQ into liposomes (HCQ/Lip) decorated with a pH-sensitive TH-RGD ... ...

    Abstract Hydroxychloroquine (HCQ) inhibits autophagy and therefore can sensitize some cancer cells to chemotherapy, but the high doses required limit its clinical use. Here we show that loading HCQ into liposomes (HCQ/Lip) decorated with a pH-sensitive TH-RGD targeting peptide (HCQ/Lip-TR) can concentrate HCQ in B16F10 tumor cells and lysosomes. HCQ/Lip-TR was efficiently internalized as a result of its ability to bind ITGAV-ITGB3/integrin αvβ3 receptors highly expressed on the tumor cell surface and to undergo charge reversal from anionic at pH 7.4 to cationic at pH 6.5. Studies in vitro at pH 6.5 showed that the intracellular HCQ concentration was 35.68-fold higher, and lysosomal HCQ concentration 32.22-fold higher, after treating cultures with HCQ/Lip-TR than after treating them with free HCQ. The corresponding enhancements observed in mice bearing B16F10 tumors were 15.16-fold within tumor cells and 14.10-fold within lysosomes. HCQ/Lip-TR was associated with milder anemia and milder myosuppressive reductions in white blood cell and platelet counts than free HCQ, as well as less accumulation in the small intestine, which may reduce risk of intestinal side effects. In addition, co-delivering HCQ/Lip-TR with either free doxorubicin (DOX) or liposomal DOX improved the ability of DOX to inhibit tumor growth. Biochemical, electron microscopy and immunofluorescence experiments confirmed that HCQ/Lip-TR blocked autophagic flux in tumor cells. Our results suggest that loading HCQ into Lip-TR liposomes may increase the effective concentration of the inhibitor in tumor cells, allowing less toxic doses to be used.
    MeSH term(s) Animals ; Antineoplastic Agents/pharmacology ; Autophagy/drug effects ; Biophysical Phenomena ; Doxorubicin/analogs & derivatives ; Doxorubicin/pharmacology ; Drug Delivery Systems ; Female ; Humans ; Hydrogen-Ion Concentration ; Hydroxychloroquine/administration & dosage ; Hydroxychloroquine/pharmacology ; Lysosomes/drug effects ; Lysosomes/metabolism ; MCF-7 Cells ; Melanoma, Experimental/pathology ; Mice, Inbred C57BL ; Models, Biological ; Peptides/pharmacology ; Polyethylene Glycols/pharmacology
    Chemical Substances Antineoplastic Agents ; Peptides ; liposomal doxorubicin ; Polyethylene Glycols (3WJQ0SDW1A) ; Hydroxychloroquine (4QWG6N8QKH) ; Doxorubicin (80168379AG)
    Language English
    Publishing date 2016-04-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2454135-7
    ISSN 1554-8635 ; 1554-8627
    ISSN (online) 1554-8635
    ISSN 1554-8627
    DOI 10.1080/15548627.2016.1162930
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6741: Show issues Location:
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