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  1. Book ; Online ; E-Book: Yangzi waters

    Gao, Yan

    transforming the water regime of the Jianghan Plain in late imperial China

    (China Studies)

    2022  

    Abstract: This book centers on the changes of polders and investigates the complex hydro-social relationships of the Jianghan Plain in late imperial China. Once a "hydraulic frontier" where local communities managed the polders, the Jianghan Plain became a state- ... ...

    Author's details by Yan Gao
    Series title China Studies
    Abstract "This book centers on the changes of polders and investigates the complex hydro-social relationships of the Jianghan Plain in late imperial China. Once a "hydraulic frontier" where local communities managed the polders, the Jianghan Plain became a state-led hydro-electric powerhouse by the mid-twentieth century. Through meticulous historical analysis, this book shows how water politics, cultural practice, and ecology interplayed and transformed the landscape and waterscape of the plain from a long-term perspective. By touching on topics such as religious beliefs, ethnic tension and militarization, the author reveals a plain in between nature and culture that has never been fully examined before"--
    Keywords Water resources development/History ; Yangtze River (China) ; Jianghan Region (China) ; China
    Subject code 333.910095121
    Language English
    Size 1 online resource (289 pages)
    Publisher Brill
    Publishing place Leiden, The Netherlands ; Boston
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 9789004505285 ; 9789004505278 ; 9004505288 ; 900450527X
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online ; E-Book: Biology of vascular smooth muscle

    Gao, Yuansheng

    vasoconstriction and dilatation

    2022  

    Author's details Yuansheng Gao
    Keywords Vascular smooth muscle ; Vascular smooth muscle/Physiology ; Múscul llis ; Sistema cardiovascular ; Fisiologia humana
    Subject code 599.0116
    Language English
    Size 1 online resource (422 pages)
    Edition 2nd ed.
    Publisher Springer
    Publishing place Singapore
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 9789811971228 ; 9789811971211 ; 9811971226 ; 9811971218
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book: Biology of Vascular Smooth Muscle

    Gao, Yuansheng

    Vasoconstriction and Dilatation

    2022  

    Author's details Dr. Yuansheng Gao received a diploma in military medicine from the Fourth Military Medical University (now Air Force Medical University) in Xian, China in 1977, and a master degree in physiology from Beijing Medical College (now Peking University Health Science Center) in Beijing, China in 1982. He received his PhD in physiology (supervisor: Paul M Vanhoutte) in 1990 from Mayo Graduate School (now Mayo Clinic Graduate School of Biomedical Sciences), MN, USA and obtained his postdoctoral training (supervisor: Paul M Vanhoutte) from 1990 to 1992 at Baylor College of Medicine, TX, USA. He was an adjunct assistant professor (1992-1999) and adjunct associate professor (1999- 2002) in Dr. Usha J Raj's laboratory at the Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, CA, USA, a professor at the Department of Physiology and Pathophysiology at Peking University Health Science Center from 2002 to 2014, a visiting professor at the Department of Pediatrics, University of Illinoi
    Keywords vasoreactivity ; cAMP-PKA signaling ; cGMP-PKG signaling ; vasoconstriction and dilatation regulators ; Vasculature ; vascular smooth muscle
    Language English
    Size 440 p.
    Edition 2
    Publisher Springer Nature Singapore
    Document type Book
    Note PDA Manuell_17
    Format 160 x 241 x 30
    ISBN 9789811971211 ; 9811971218
    Database PDA

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  4. Book ; Online: Covalent Organic Frameworks

    Gao, Yanan / Lu, Fei

    2023  

    Keywords Organic chemistry ; Chemistry
    Language English
    Size 1 electronic resource (122 pages)
    Publisher IntechOpen
    Document type Book ; Online
    Note English
    HBZ-ID HT030377695
    ISBN 9781803569611 ; 1803569611
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  5. Article: Design of urban innovation space system using artificial intelligence technology and internet of things.

    Gao, Yifang

    Heliyon

    2024  Volume 10, Issue 3, Page(s) e25396

    Abstract: The goal of this paper is to integrate artificial intelligence (AI) and Internet of things (IoT) technology into urban innovation space systems while expediting the construction of urban informatization. The core of the paper is to build an innovation ... ...

    Abstract The goal of this paper is to integrate artificial intelligence (AI) and Internet of things (IoT) technology into urban innovation space systems while expediting the construction of urban informatization. The core of the paper is to build an innovation space system, which is developed around three key components: innovation elements, innovation networks and innovation bases. First, the definition of innovation space is investigated in detail, and the essence of innovation space is understood to ensure that the key elements in the innovation process can be accurately captured and analyzed in the follow-up research. Second, it is clear that Chengdu is a representative city in Sichuan Province. Through the research in this area, people can deeply understand the specific background and characteristics of urban innovation space system. Then, the innovation space system is constructed, which is supported by innovation elements, innovation networks and innovation bases. These three components are intertwined, which together constitute the key elements of urban innovation space. Furthermore, the Internet worm technology is integrated with the IoT technology, and the system is visually inspected with the help of AI. The application of IoT technology helps to realize the automation and information sharing of the system, while the use of AI provides a deep insight into the system structure and operation. Through this research process, people can fully understand the construction process of Chengdu innovation space system, and provide deeper insight and support for urban innovation through the application of IoT and AI technology. The results show that while Chengdu's entrepreneurship and innovation enterprises are dispersed throughout all of the city's districts and counties, the city's academic talent and the bulk of its higher education institutions are concentrated in the city's core. There are 275 entrepreneurship and innovation enterprises in the High-tech District of Chengdu, which is the most densely distributed area. An urban innovation space network is being built by eight distinct research and higher education establishments. As urban innovation spaces are being built, emphasis should be given to the regional aggregation features of talents, higher education and research institutions, as well as entrepreneurship and innovation business enterprises. The innovation space system based on Internet worm technology of the IoT shows excellent performance in real-time identification of innovation elements, network connection quality, sensor monitoring, AI visual monitoring and so on. The system performs well in real-time monitoring of new enterprises and projects, and the real-time recognition rate reaches 98 %. The communication quality of the innovation network is relatively stable, and the connection quality reaches 92 %. The accuracy of sensor status monitoring in the IoT is high, reaching 99 %. The coverage of AI vision monitoring system reaches 96 %, effectively monitoring the areas involved in innovative space systems. Generally speaking, through the combination of theory and practice, this paaper provides comprehensive and specific guidance for the construction of urban innovation space system, promotes the research progress in this field, and makes beneficial contributions to the sustainable development of urban innovation and informatization.
    Language English
    Publishing date 2024-01-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e25396
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Progress in atypical lobular hyperplasia: Striking a balance between active surveillance and minimally invasive interventions.

    Gao, Yinguang

    World journal of surgery

    2024  

    Language English
    Publishing date 2024-04-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 224043-9
    ISSN 1432-2323 ; 0364-2313
    ISSN (online) 1432-2323
    ISSN 0364-2313
    DOI 10.1002/wjs.12165
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1336: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Book ; Online ; E-Book: Biology of vascular smooth muscle: Vasoconstriction and dilatation

    Gao, Yuansheng

    2017  

    Author's details Yuansheng Gao
    Keywords Medicine ; Human physiology ; Molecular biology ; Angiology ; Cell physiology
    Subject code 612
    Language English
    Size 1 Online-Ressource (xiii, 286 Seiten), Illustrationen
    Publisher Springer
    Publishing place Singapore
    Publishing country Singapore
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019413554
    ISBN 978-981-10-4810-4 ; 9789811048098 ; 981-10-4810-X ; 9811048096
    DOI 10.1007/978-981-10-4810-4
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  8. Article ; Online: Oncolytic Therapy of Solid Tumors by Modified Vesicular Stomatitis Virus.

    Gao, Yanhua

    DNA and cell biology

    2023  Volume 43, Issue 2, Page(s) 57–60

    Abstract: Vesicular stomatitis virus (VSV) is a promising oncolytic virus for treating solid tumors. We recently engineered a replicating VSV that specifically targets and ... ...

    Abstract Vesicular stomatitis virus (VSV) is a promising oncolytic virus for treating solid tumors. We recently engineered a replicating VSV that specifically targets and destroys
    MeSH term(s) Animals ; Humans ; Oncolytic Virotherapy ; Vesicular Stomatitis/therapy ; Vesicular stomatitis Indiana virus/genetics ; Neoplasms/genetics ; Neoplasms/therapy ; Oncolytic Viruses/genetics ; Cell Line, Tumor
    Language English
    Publishing date 2023-12-11
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 1024454-2
    ISSN 1557-7430 ; 0198-0238 ; 1044-5498
    ISSN (online) 1557-7430
    ISSN 0198-0238 ; 1044-5498
    DOI 10.1089/dna.2023.0368
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2061: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Impact of the number of cycles of platinum-based chemotherapy for early stage ovarian clear cell carcinoma on survival: a retrospective study.

    Gao, Yang

    BMC women's health

    2023  Volume 23, Issue 1, Page(s) 262

    Abstract: Background: Ovarian clear cell carcinoma (OCCC) is a unique subtype of ovarian epithelial ovarian cancer. The number of chemotherapy cycles for early-stage patients is still debated. This study aimed to evaluate whether at least 4 cycles of adjuvant ... ...

    Abstract Background: Ovarian clear cell carcinoma (OCCC) is a unique subtype of ovarian epithelial ovarian cancer. The number of chemotherapy cycles for early-stage patients is still debated. This study aimed to evaluate whether at least 4 cycles of adjuvant platinum-based chemotherapy have better prognostic value than 1-3 cycles in early-stage OCCC.
    Methods: We retrospectively retrieved data from 102 patients with stage I-IIA OCCC between 2008 and 2017. All patients underwent complete surgical staging followed by adjuvant platinum-based chemotherapy. Kaplan-Meier curves and Multivariate Cox analysis were performed to estimate 5-year overall survival (OS) and progression-free (PFS) according to the number of chemotherapy cycles.
    Results: Among stage I-IIA disease, twenty (19.6%) patients received 1-3 cycles, and eighty-two (80.4%) patients received at least 4 cycles of adjuvant chemotherapy. Univariate analysis revealed that the patients in 1-3cycles group had not significantly improved 5-year OS and PFS than those in the ≥ 4 cycles group (5-year OS: hazard ratio [HR] 1.21; 95% confidence interval [CI] 0.25- 5.78, p = 0.1), and 5-year PFS: HR 0.79; 95% CI 0.26- 2.34, p = 0.1). In the multivariate analysis, there was no impact of 1-3 versus ≥ 4 cycles of chemotherapy on 5-year OS (HR 1.21, 95% CI 0.25-3.89, p = 0.8) or 5-year PFS (HR 0.94, 95% CI 0.32-2.71, p = 0.9). The potential independent risk factors associated with 5-year OS and PFS included the surgery approach and FIGO stage.
    Conclusion: The number of cycles of platinum-based chemotherapy could not be associated with a survival benefit for patients with early-stage OCCC.
    MeSH term(s) Female ; Humans ; Ovarian Neoplasms/pathology ; Retrospective Studies ; Platinum/therapeutic use ; Neoplasm Staging ; Disease-Free Survival ; Carcinoma, Ovarian Epithelial/drug therapy ; Chemotherapy, Adjuvant ; Adenocarcinoma, Clear Cell/drug therapy ; Adenocarcinoma, Clear Cell/pathology
    Chemical Substances Platinum (49DFR088MY)
    Language English
    Publishing date 2023-05-15
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2050444-5
    ISSN 1472-6874 ; 1472-6874
    ISSN (online) 1472-6874
    ISSN 1472-6874
    DOI 10.1186/s12905-023-02405-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: A computational model of learning flexible navigation in a maze by layout-conforming replay of place cells.

    Gao, Yuanxiang

    Frontiers in computational neuroscience

    2023  Volume 17, Page(s) 1053097

    Abstract: Recent experimental observations have shown that the reactivation of hippocampal place cells (PC) during sleep or wakeful immobility depicts trajectories that can go around barriers and can flexibly adapt to a changing maze layout. However, existing ... ...

    Abstract Recent experimental observations have shown that the reactivation of hippocampal place cells (PC) during sleep or wakeful immobility depicts trajectories that can go around barriers and can flexibly adapt to a changing maze layout. However, existing computational models of replay fall short of generating such layout-conforming replay, restricting their usage to simple environments, like linear tracks or open fields. In this paper, we propose a computational model that generates layout-conforming replay and explains how such replay drives the learning of flexible navigation in a maze. First, we propose a Hebbian-like rule to learn the inter-PC synaptic strength during exploration. Then we use a continuous attractor network (CAN) with feedback inhibition to model the interaction among place cells and hippocampal interneurons. The activity bump of place cells drifts along paths in the maze, which models layout-conforming replay. During replay in sleep, the synaptic strengths from place cells to striatal medium spiny neurons (MSN) are learned by a novel dopamine-modulated three-factor rule to store place-reward associations. During goal-directed navigation, the CAN periodically generates replay trajectories from the animal's location for path planning, and the trajectory leading to a maximal MSN activity is followed by the animal. We have implemented our model into a high-fidelity virtual rat in the MuJoCo physics simulator. Extensive experiments have demonstrated that its superior flexibility during navigation in a maze is due to a continuous re-learning of inter-PC and PC-MSN synaptic strength.
    Language English
    Publishing date 2023-02-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2452964-3
    ISSN 1662-5188
    ISSN 1662-5188
    DOI 10.3389/fncom.2023.1053097
    Database MEDical Literature Analysis and Retrieval System OnLINE

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