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Article ; Online: High loading FeS2 nanoparticles anchored on biomass-derived carbon tube as low cost and long cycle anode for sodium-ion batteries

Kongyao Chen / Gaojie Li / Yanjie Wang / Weihua Chen / Liwei Mi

Green Energy & Environment, Vol 5, Iss 1, Pp 50-

2020 Volume 58

Abstract: In recent years, the sodium storage mechanism and performance optimization of FeS2 have been studied intensively. However, before the commercial application of FeS2, preconditions of low-cost, simple craft and scale production of nanoscale FeS2 are also ... ...

Abstract	In recent years, the sodium storage mechanism and performance optimization of FeS2 have been studied intensively. However, before the commercial application of FeS2, preconditions of low-cost, simple craft and scale production of nanoscale FeS2 are also essential. Based on above challenges, mesh-like FeS2/carbon tube/FeS2 composites are prepared simply from green, low-cost and renewable natural herb in this work. With the assistance of protogenetic interconnected carbon tube network (only 5.3 wt%), FeS2/carbon tube/FeS2 composites show high capacity (542.2 mA h g−1), good stability (< 0.005% per cycle over 1000 cycles), and excellent rate performance (426.2 mA h g−1 at 2 A g−1). The outstanding electrochemical performance of FeS2/carbon tube/FeS2 composites may be attributed to the unique interconnected reticular structure, meaning that FeS2 nanoparticles are effectively immobilized by carbon tube network via physical encapsulation and chemical bonding. More importantly, this work may provide green and low cost preparation method for specially structured metal sulfides/carbon composites, which promotes their commercial utilization in environmentally friendly energy storage system. Keywords: FeS2, Biomass-drived carbon, Mesh-like structure, Low cost, Sodium-ion batteries
Keywords	Renewable energy sources ; TJ807-830 ; Ecology ; QH540-549.5
Subject code	620
Language	English
Publishing date	2020-01-01T00:00:00Z
Publisher	KeAi Communications Co., Ltd.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: The association between doctors’ presenteeism and job burnout

Pei Pei / Guohua Lin / Gaojie Li / Yifan Zhu / Xiaoyu Xi

BMC Health Services Research, Vol 20, Iss 1, Pp 1-

a cross-sectional survey study in China

2020 Volume 7

Abstract: Abstract Background It is necessary to examine doctors working with illness from a professional point of view, because it is not only related to their occupational health, but more importantly, will affect the treatment effect of patients and the overall ...

Abstract	Abstract Background It is necessary to examine doctors working with illness from a professional point of view, because it is not only related to their occupational health, but more importantly, will affect the treatment effect of patients and the overall medical level of the hospital. The purpose of this study was to explore the relationship between doctors’ presenteeism and job burnout, and to identify other factors that are associated with presenteeism. Methods A cross-sectional survey involving doctors (except for primary doctors) was conducted in China. Using one item measure about presenteeism and a 15-item Chinese version of the BMI-GS questionnaire, this study investigated prevalence of doctors’ presenteeism and job burnout, and determined the relationship between presenteeism and job burnout by logistical model. Results Relationship between presenteeism and job burnout were explored, and the influence of work factors were evaluated. The survey was completed by 1376/1547 hospital doctors, with a response rate of 88.9%. Presenteeism was reported by 30.7% of participants. Using MBI-GS, 86.8% of all doctors had moderate job burnout and 6.0%(n = 82) were severe job burnout. Logistic regression analysis showed that doctors with medium, high degree of emotional exhaustion and high degree of cynicism were more likely to practice presenteeism (all p < 0.05). In addition, two other work-related factors, including the doctors’ department and position, were also likely to relate with presenteeism (all p < 0.05). Conclusions By examining the relationship between presenteeism and job burnout, this study determined that there is indeed a significant correlation between the two. This result has a certain reference value for the development of work health, especially presenteeism and job burnout theory, and also makes a certain contribution to the relevant research literature.
Keywords	Presenteeism ; Job burnout ; Emotional exhaustion ; Cynicism ; Doctors ; Public aspects of medicine ; RA1-1270
Subject code	300
Language	English
Publishing date	2020-08-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Role of Nramp transporter genes of Spirodela polyrhiza in cadmium accumulation

Yan Chen / Gaojie Li / Jingjing Yang / Xuyao Zhao / Zuoliang Sun / Hongwei Hou

Ecotoxicology and Environmental Safety, Vol 227, Iss , Pp 112907- (2021)

2021

Abstract: As a pollutant, Cd causes severe impact to the environment and damages living organisms. It can be uptaken from the environment by the natural resistance-associated macrophage protein (Nramp) in plants. However, the ion absorption function of Nramp ... ...

Abstract	As a pollutant, Cd causes severe impact to the environment and damages living organisms. It can be uptaken from the environment by the natural resistance-associated macrophage protein (Nramp) in plants. However, the ion absorption function of Nramp transporter genes in Spirodela polyrhiza has not been reported. In this study, SpNramp1, SpNramp2, and SpNramp3 from S. polyrhiza were cloned and their functions were analyzed in S. polyrhiza and yeast. Growth parameters and physicochemical indices of wild-type and transgenic lines were measured under Cd stress. Results revealed that SpNramp1, SpNramp2, and SpNramp3 were identified as plasma membrane-localized transporters, and their roles in transporting Cd were verified in yeast. In S. polyrhiza, SpNramp1 overexpression significantly increased the content of Cd, Fe, Mn, and fresh weight. SpNramp2 overexpression increased Mn and Cd. SpNramp3 overexpression increased Fe and Mn concentrations. These results indicate that SpNramp1, SpNramp2, and SpNramp3 had a different preference for ion absorption. Two S. polyrhiza transgenic lines (OE1 and OE3) were obtained. One of them (OE1) showed a stronger accumulation ability, and the other one (OE3) exhibited tolerance capacity to Cd. This study provides new insight into the functions of SpNramp1, SpNramp2, and SpNramp3 and obtains important enrichment lines (OE1) for manipulating Cd accumulation, phytoremediation, and ecological safety.
Keywords	Nramp transporter genes ; Yeast ; Subcellular localization ; Cd accumulation ; Phytoremediation ; Environmental pollution ; TD172-193.5 ; Environmental sciences ; GE1-350
Subject code	580
Language	English
Publishing date	2021-12-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Mechanisms of the Morphological Plasticity Induced by Phytohormones and the Environment in Plants

Gaojie Li / Shiqi Hu / Xuyao Zhao / Sunjeet Kumar / Yixian Li / Jingjing Yang / Hongwei Hou

International Journal of Molecular Sciences, Vol 22, Iss 2, p

2021 Volume 765

Abstract: Plants adapt to environmental changes by regulating their development and growth. As an important interface between plants and their environment, leaf morphogenesis varies between species, populations, or even shows plasticity within individuals. Leaf ... ...

Abstract	Plants adapt to environmental changes by regulating their development and growth. As an important interface between plants and their environment, leaf morphogenesis varies between species, populations, or even shows plasticity within individuals. Leaf growth is dependent on many environmental factors, such as light, temperature, and submergence. Phytohormones play key functions in leaf development and can act as molecular regulatory elements in response to environmental signals. In this review, we discuss the current knowledge on the effects of different environmental factors and phytohormone pathways on morphological plasticity and intend to summarize the advances in leaf development. In addition, we detail the molecular mechanisms of heterophylly, the representative of leaf plasticity, providing novel insights into phytohormones and the environmental adaptation in plants.
Keywords	environment ; leaf ; morphological plasticity ; phytohormones ; molecular mechanism ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
Subject code	580
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Clinical and economic outcomes of hospital pharmaceutical care

Guohua Lin / Rong Huang / Jing Zhang / Gaojie Li / Lei Chen / Xiaoyu Xi

BMC Health Services Research, Vol 20, Iss 1, Pp 1-

a systematic review and meta-analysis

2020 Volume 14

Abstract: Abstract Background Hospital clinical pharmacists have been working in many countries for many years and clinical pharmaceutical care have a positive effect on the recovery of patients. In order to evaluate the clinical effectiveness and economic ... ...

Abstract	Abstract Background Hospital clinical pharmacists have been working in many countries for many years and clinical pharmaceutical care have a positive effect on the recovery of patients. In order to evaluate the clinical effectiveness and economic outcomes of clinical pharmaceutical care, relevant clinical trial studies were reviewed and analysed. Methods Two researchers searched literatures published from January 1992 to October 2019, and screened them by keywords like pharmaceutical care, pharmaceutical services, pharmacist interventions, outcomes, effects, impact, etc. Then, duplicate literatures were removed and the titles, abstracts and texts were read to screen literatures according to inclusion and exclusion criteria. Key data in the literature were extracted, and Meta-analysis was conducted using the literature with common outcome indicators. Results A total of 3299 articles were retrieved, and 42 studies were finally included. Twelve of them were used for meta-analysis. Among the 42 studies included, the main results of pharmaceutical care showed positive effects, 36 experimental groups were significantly better than the control group, and the remaining 6 studies showed mixed or no effects. Meta-analysis showed that clinical pharmacists had significant effects on reducing systolic blood pressure and diastolic blood pressure and shortening hospitalization days (P < 0.05), but no statistical significance in reducing medical costs (P > 0.05). Conclusion Clinical pharmacists’ pharmaceutical care has a significant positive effect on patients’ clinical effects, but has no significant economic effect.
Keywords	Pharmaceutical care ; Systematic review ; Meta-analysis ; Public aspects of medicine ; RA1-1270
Subject code	610
Language	English
Publishing date	2020-06-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Genome-Wide Identification of the Nramp Gene Family in Spirodela polyrhiza and Expression Analysis under Cadmium Stress

Yan Chen / Xuyao Zhao / Gaojie Li / Sunjeet Kumar / Zuoliang Sun / Yixian Li / Wenjun Guo / Jingjing Yang / Hongwei Hou

International Journal of Molecular Sciences, Vol 22, Iss 6414, p

2021 Volume 6414

Abstract: Natural resistance-associated macrophage proteins (Nramps) are specific metal transporters in plants with different functions among various species. The evolutionary and functional information of the Nramp gene family in Spirodela polyrhiza has not been ... ...

Abstract	Natural resistance-associated macrophage proteins (Nramps) are specific metal transporters in plants with different functions among various species. The evolutionary and functional information of the Nramp gene family in Spirodela polyrhiza has not been previously reported in detail. To identify the Nramp genes in S. polyrhiza , we performed genome-wide identification, characterization, classification, and cis-elements analysis among 22 species with 138 amino acid sequences. We also conducted chromosomal localization and analyzed the synteny relationship, promoter, subcellular localization, and expression patterns in S. polyrhiza . β-Glucuronidase staining indicated that SpNramp 1 and SpNramp3 mainly accumulated in the root and joint between mother and daughter frond. Moreover, SpNramp1 was also widely displayed in the frond. SpNramp2 was intensively distributed in the root and frond. Quantitative real-time PCR results proved that the SpNramp gene expression level was influenced by Cd stress, especially in response to Fe or Mn deficiency. The study provides detailed information on the SpNramp gene family and their distribution and expression, laying a beneficial foundation for functional research.
Keywords	Spirodela polyrhiza ; Nramp family ; promoter ; Cd ; Fe or Mn limiting ; gene expression profiling ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
Subject code	580
Language	English
Publishing date	2021-06-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Once-monthly hemin suppresses inflammatory and autoreactive CD4+ T cell responses to robustly ameliorate experimental rheumatoid arthritis

Bingzhi Sun / Gaojie Li / Ling Guo / Na Yin / Huan Huang / Xiaodong Wu / Runyue Huang / Min Feng

iScience, Vol 24, Iss 10, Pp 103101- (2021)

2021

Abstract: Summary: Rheumatoid arthritis (RA) is an inflammatory autoimmune disease that would permanently damage the affected joints. Unfortunately, a large proportion of RA patients fail to respond adequately to current treatments. Here, repurposing hemin and its ...

Abstract	Summary: Rheumatoid arthritis (RA) is an inflammatory autoimmune disease that would permanently damage the affected joints. Unfortunately, a large proportion of RA patients fail to respond adequately to current treatments. Here, repurposing hemin and its ultra-long-acting formulation were explored for the effective treatment of RA in animal models. We provided evidence that hemin prevented the onset and ameliorated the clinical course of RA. Notably, hemin treatment rescued the dysregulated gene expression in animal models of RA, resulting in attenuation of Th1/Th17 cell-mediated responses and proinflammatory cytokines. Moreover, we further formulated hemin into the in-situ forming implant, and a single injection of the ultra-long-acting hemin exerted potent disease-modifying effects for at least six weeks with a remarkable dose reduction. Taken together, given the potent anti-inflammatory and immunosuppressive effects, the once-monthly hemin injection holds promise for rapid clinical translation, and represents a potential strategy to treat RA and possibly other autoimmune diseases.
Keywords	Science ; Q
Subject code	610
Language	English
Publishing date	2021-10-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Single-Nucleotide Resolution Mapping of N6‑Methyladenine in Genomic DNA

Cheng-Jie Ma / Gaojie Li / Wen-Xuan Shao / Yi-Hao Min / Ping Wang / Jiang-Hui Ding / Neng-Bin Xie / Min Wang / Feng Tang / Yu-Qi Feng / Weimin Ci / Yinsheng Wang / Bi-Feng Yuan

ACS Central Science, Vol 9, Iss 9, Pp 1799-

2023 Volume 1809

Keywords	Chemistry ; QD1-999
Language	English
Publishing date	2023-08-01T00:00:00Z
Publisher	American Chemical Society
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Identification, Structural, and Expression Analyses of SPX Genes in Giant Duckweed ( Spirodela polyrhiza ) Reveals Its Role in Response to Low Phosphorus and Nitrogen Stresses

Jingjing Yang / Xuyao Zhao / Yan Chen / Gaojie Li / Xiaozhe Li / Manli Xia / Zuoliang Sun / Yimeng Chen / Yixian Li / Lunguang Yao / Hongwei Hou

Cells, Vol 11, Iss 1167, p

2022 Volume 1167

Abstract: SPX genes play important roles in the coordinated utilization of nitrogen (N) and phosphorus (P) in plants. However, a genome-wide analysis of the SPX family is still lacking. In this study, the gene structure and phylogenetic relationship of 160 SPX ... ...

Abstract	SPX genes play important roles in the coordinated utilization of nitrogen (N) and phosphorus (P) in plants. However, a genome-wide analysis of the SPX family is still lacking. In this study, the gene structure and phylogenetic relationship of 160 SPX genes were systematically analyzed at the genome-wide level. Results revealed that SPX genes were highly conserved in plants. All SPX genes contained the conserved SPX domain containing motifs 2, 3, 4, and 8. The 160 SPX genes were divided into five clades and the SPX genes within the same clade shared a similar motif composition. P1BS cis –elements showed a high frequency in the promoter region of SPX s, indicating that SPX genes could interact with the P signal center regulatory gene Phosphate Starvation Response1 ( PHR1 ) in response to low P stress. Other cis –elements were also involved in plant development and biotic/abiotic stress, suggesting the functional diversity of SPX s. Further studies were conducted on the interaction network of three SpSPXs , revealing that these genes could interact with important components of the P signaling network. The expression profiles showed that SpSPX s responded sensitively to N and P deficiency stresses, thus playing a key regulatory function in P and N metabolism. Furthermore, the expression of SpSPXs under P and N deficiency stresses could be affected by environmental factors such as ABA treatment, osmotic, and LT stresses. Our study suggested that SpSPXs could be good candidates for enhancing the uptake ability of Spirodela polyrhiza for P nutrients in wastewater. These findings could broaden the understanding of the evolution and biological function of the SPX family and offer a foundation to further investigate this family in plants.
Keywords	SPX ; Spirodela polyrhiza ; phosphorus stress ; nitrogen stress ; gene structure ; gene expression profiling ; Biology (General) ; QH301-705.5
Subject code	572 ; 580
Language	English
Publishing date	2022-03-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Mid-Cretaceous desert system in the Simao Basin, southwestern China, and its implications for sea-level change during a greenhouse climate

Wu, Chihua / Chenglin Liu / Haisheng Yi / Guoqing Xia / Hua Zhang / Licheng Wang / Gaojie Li / Michael Wagreich

Palaeogeography, palaeoclimatology, palaeoecology. 2017 Feb. 15, v. 468

2017

Abstract: Paleoclimatic indicators suggest that the mid-Cretaceous was one of the warmest intervals of the Phanerozoic. The period of the mid-Cretaceous âsuper-greenhouseâ also experienced an equator-to-pole temperature gradient much lower than that of the ... ...

Abstract	Paleoclimatic indicators suggest that the mid-Cretaceous was one of the warmest intervals of the Phanerozoic. The period of the mid-Cretaceous âsuper-greenhouseâ also experienced an equator-to-pole temperature gradient much lower than that of the present day, implying greater meridional heat transport by the atmosphere and/or oceans. However, reconstructions of Cretaceous atmospheric circulation have been hindered by a lack of relevant datasets based on reliable proxies or direct geological evidence. Aeolian deposits provide direct information about paleoclimate, as well as the direction and intensity of paleo-wind in the interiors of continents. Using petrologic and sedimentologic observations, this study reassesses the terrestrial deposits of the mid-Cretaceous Mangang Formation in the Simao Basin of southwestern China. Originally considered to be aqueous deposits, we reinterpret these strata as representing aeolian transport in a desert environment. We suggest that the development of aeolian deposits in the Mangang Formation (and coeval strata in adjacent basins) was a local response to the prevailing desert climate in the mid- to low-latitudes of the Northern Hemisphere during the mid-Cretaceous, which were dominated by subtropical high-pressure systems on a planetary scale. In addition, with the closure of the Mesotethys Ocean, the intermontane basins of the South China, Simao, and Indochina blocks became more isolated from atmospheric circulation. Bidirectional subduction of the Bangong-Nujiang oceanic crust and the Izanagi Plate beneath East Asia led to the development of Andean-type margins, which created a rain-shadow effect in continental East Asia. These factors caused the development of a tropical desert climate, characterized by aeolian dunes and evaporite deposition. We speculate that the severe depletion of groundwater reservoirs via the desertification of East Asia may represent a previously unrecognized trigger for short-term sea-level changes during the ice-free Cretaceous greenhouse interval.
Keywords	atmospheric circulation ; basins ; climate ; data collection ; desertification ; dunes ; eolian deposits ; greenhouse effect ; groundwater ; heat ; latitude ; oceans ; paleoclimatology ; sea level ; China ; Indochina
Language	English
Dates of publication	2017-0215
Size	p. 529-544.
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	417718-6
ISSN	0031-0182
ISSN	0031-0182
DOI	10.1016/j.palaeo.2016.12.048
Database	NAL-Catalogue (AGRICOLA)

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