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  1. AU="García, Patricia J"
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  1. Book ; Online ; E-Book: Manson's tropical diseases

    Manson, Patrick / Farrar, Jeremy / Hotez, Peter J. / Junghanss, Thomas / Kang, Gagandeep / Lalloo, David / White, Nicholas J. / Garcia, Patricia J.

    2024  

    Title variant Tropical diseases
    Author's details Jeremy Farrar, Peter J. Hotez, Thomas Junghanss, Gagandeep Kang, David Lalloo, Nicholas J. White, Patricia J. Garcia
    Keywords Tropical medicine ; Tropenkrankheit ; Tropenmedizin
    Language English
    Size 1 Online-Ressource (5477 Seiten), Illustrationen, Diagramme
    Edition Twenty-third edition
    Publisher Elsevier
    Publishing place London
    Publishing country Great Britain
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT030592106
    ISBN 978-0-7020-7961-0 ; 9780702079597 ; 0-7020-7961-8 ; 0702079596
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Women's leadership and gender equality in Latin America: the journey is far from over.

    Garcia, Patricia J

    BMJ (Clinical research ed.)

    2024  Volume 384, Page(s) q575

    MeSH term(s) Female ; Humans ; Latin America ; Leadership ; Gender Equity ; Socioeconomic Factors ; Women's Rights
    Language English
    Publishing date 2024-03-07
    Publishing country England
    Document type Editorial
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj.q575
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book: Manson's Tropical Diseases

    Lalloo, David / Kang, Gagandeep / Farrar, Jeremy / White, Nicholas J. / Garcia, Patricia J. / Hotez, Peter J / Junghanss, Thomas Section Clinical Tropical Medicine University Hospital Heidelberg Heidelberg

    2023  

    Author's details Jeremy Farrar, FRCP, FMedAcSci, DPhil, OBE§Wellcome Trust §(From 5 May 2023 Chief Scientist World Health Organization)
    Size 1384 p.
    Publisher Elsevier Science
    Document type Book
    Note PDA Manuell_22
    Format 225 x 283 x 53
    ISBN 9780702079597 ; 0702079596
    Database PDA

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  4. Article ; Online: Corruption in global health: the open secret.

    García, Patricia J

    Lancet (London, England)

    2019  Volume 394, Issue 10214, Page(s) 2119–2124

    Abstract: Corruption is embedded in health systems. Throughout my life-as a researcher, public health worker, and a Minister of Health-I have been able to see entrenched dishonesty and fraud. But despite being one of the most important barriers to implementing ... ...

    Abstract Corruption is embedded in health systems. Throughout my life-as a researcher, public health worker, and a Minister of Health-I have been able to see entrenched dishonesty and fraud. But despite being one of the most important barriers to implementing universal health coverage around the world, corruption is rarely openly discussed. In this Lecture, I outline the magnitude of the problem of corruption, how it started, and what is happening now. I also outline people's fears around the topic, what is needed to address corruption, and the responsibilities of the academic and research communities in all countries, irrespective of their level of economic development. Policy makers, researchers, and funders need to think about corruption as an important area of research in the same way we think about diseases. If we are really aiming to achieve the Sustainable Development Goals and ensure healthy lives for all, corruption in global health must no longer be an open secret.
    MeSH term(s) Biomedical Research ; Crime ; Fraud ; Global Health ; Health Care Sector ; Humans ; International Cooperation ; Professional Misconduct ; Social Responsibility ; Universal Health Care
    Language English
    Publishing date 2019-11-27
    Publishing country England
    Document type Journal Article ; Lecture ; Review
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(19)32527-9
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  5. Article ; Online: Challenges in implementation of public policies in aging and dementia in Peru.

    Diaz, Monica M / Pintado-Caipa, Maritza / Garcia, Patricia J

    PLOS global public health

    2023  Volume 3, Issue 9, Page(s) e0002345

    Language English
    Publishing date 2023-09-07
    Publishing country United States
    Document type Journal Article
    ISSN 2767-3375
    ISSN (online) 2767-3375
    DOI 10.1371/journal.pgph.0002345
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  6. Article ; Online: Lessons from Peru to reduce under-5 mortality: understanding program implementation and context.

    García, Patricia J / Williams, Anna Larson / Carcamo, Marco H / VanderZanden, Amelia / Binagwaho, Agnes

    BMC pediatrics

    2024  Volume 23, Issue Suppl 1, Page(s) 646

    Abstract: Background: Health policymakers aiming to reduce under-5 mortality (U5M) often lack data regarding how successful interventions in other countries were implemented. The Exemplars in U5M Study identified countries that achieved significant reductions in ... ...

    Abstract Background: Health policymakers aiming to reduce under-5 mortality (U5M) often lack data regarding how successful interventions in other countries were implemented. The Exemplars in U5M Study identified countries that achieved significant reductions in amenable U5M. This case study in Peru used implementation research to explore the contextual factors and strategies that contributed to the successful implementation of key evidence-based interventions (EBIs).
    Methods: This research utilized a hybrid implementation research framework and a mixed-methods approach to understand the factors associated with EBI implementation and the successful reduction of U5M between 2000-2015. A desk review of existing literature on EBIs and U5M in Peru was completed, and in-depth interviews were performed with key Peruvian informants to understand the implementation strategies employed and the contextual factors that facilitated or were barriers to success. For the purposes of this analysis, three EBIs were selected and evaluated: antenatal care visits (ANC), facility-based deliveries, and infant vaccination.
    Results: Between 2000-2015, the percent of mothers attending at least four antenatal care visits rose from 69% to 96.9%, and the percent of facility-based deliveries increased from 56 to 91%. Three doses of the tetanus/diphtheria/pertussis vaccine, widely acknowledged as a key global health indicator, reached 90% by 2015. Key informants noted that economic growth, financial reforms, strong national commitment to reduce poverty in Peru, and national prioritization of maternal and child health, were important contextual factors that contributed to the successful reduction of U5M. They noted key strategies that helped achieve success during the implementation of EBIs, including utilization of data for decision-making, adaptation driven by cultural sensitivity to address gaps in coverage, and a focus on equity and anti-poverty initiatives with the participation of government, civil society, and political parties to assure continuity of policies.
    Conclusion: Several EBIs contributed to the successful reduction of U5M in Peru between 2000-2015. Strategies such as the focus on equity throughout the study period contributed to an increase in coverage of EBIs like ANC visits, facility-based deliveries and infant vaccination which worked to reduce U5M. Understanding how Peru successfully implemented programs that reduced preventable infant and child deaths could be useful to replicating this substantial public health success in other low- and middle-income countries.
    MeSH term(s) Infant ; Child ; Humans ; Pregnancy ; Female ; Peru/epidemiology ; Prenatal Care ; Poverty ; Child Health ; Mothers
    Language English
    Publishing date 2024-02-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041342-7
    ISSN 1471-2431 ; 1471-2431
    ISSN (online) 1471-2431
    ISSN 1471-2431
    DOI 10.1186/s12887-023-03890-w
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  7. Article ; Online: Syphilis.

    Peeling, Rosanna W / Mabey, David / Chen, Xiang-Sheng / Garcia, Patricia J

    Lancet (London, England)

    2023  Volume 402, Issue 10398, Page(s) 336–346

    Abstract: Syphilis is a sexually and vertically transmitted bacterial infection caused by the bacterium Treponema pallidum. Its prevalence is high in low-income and middle-income countries, and its incidence has increased in high-income countries in the last few ... ...

    Abstract Syphilis is a sexually and vertically transmitted bacterial infection caused by the bacterium Treponema pallidum. Its prevalence is high in low-income and middle-income countries, and its incidence has increased in high-income countries in the last few decades among men who have sex with men. Syphilis is a major cause of adverse pregnancy outcomes in low-income and middle-income countries. Clinical features include a primary chancre at the point of inoculation, followed weeks later by the rash of secondary syphilis, a latent period, and in some cases, involvement of the eyes, CNS, and cardiovascular systems. It is diagnosed serologically. A single intramuscular dose of long-acting benzathine penicillin is recommended for people who have had syphilis for less than 1 year and longer courses for people with late latent syphilis. Control strategies include screening and treatment of all pregnant women, and targeted interventions for groups at high risk. Vaccine development, research on antibiotic prophylaxis, and digital messaging as prevention strategies are ongoing.
    MeSH term(s) Pregnancy ; Male ; Female ; Humans ; Syphilis/diagnosis ; Syphilis/drug therapy ; Syphilis/epidemiology ; Homosexuality, Male ; Sexual and Gender Minorities ; Chancre ; Treponema pallidum ; Penicillins
    Chemical Substances Penicillins
    Language English
    Publishing date 2023-06-30
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(22)02348-0
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  8. Article ; Online: The brazilian tragedy: Where patients living at the 'Earth's lungs' die of asphyxia, and the fallacy of herd immunity is killing people.

    Malta, Monica / Strathdee, Steffanie A / Garcia, Patricia J

    EClinicalMedicine

    2021  Volume 32, Page(s) 100757

    Language English
    Publishing date 2021-02-12
    Publishing country England
    Document type Journal Article
    ISSN 2589-5370
    ISSN (online) 2589-5370
    DOI 10.1016/j.eclinm.2021.100757
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  9. Article ; Online: Assessment of regional body composition, physical function and sarcopenia among peruvian women aging with HIV: A cross-sectional study.

    Cabrera, Diego M / Cornejo, Mijahil P / Pinedo, Yvett / Garcia, Patricia J / Hsieh, Evelyn

    PLOS global public health

    2023  Volume 3, Issue 8, Page(s) e0000814

    Abstract: Management of chronic conditions and optimization of overall health has become a primary global health concern in the care of people living with HIV in the era of highly active antiretroviral therapy (ART), particularly in lower-and-middle income ... ...

    Abstract Management of chronic conditions and optimization of overall health has become a primary global health concern in the care of people living with HIV in the era of highly active antiretroviral therapy (ART), particularly in lower-and-middle income countries where infrastructure for chronic disease management may be fragmented. Alterations in body composition can reflect important changes in musculoskeletal health, particularly among populations at risk for developing fat and muscle redistribution syndromes, such as women with HIV on ART. Given the lack of data on this topic in Latin America and the Caribbean, we designed an exploratory study to measure these outcomes in a population of women aging with HIV in Peru. We conducted a cross-sectional study among Peruvian women with and without HIV aged ≥40 years. Dual X-ray absorptiometry was used to measure trunk and limb lean mass (LM) and fat mass (FM). Physical performance was assessed with the Short Physical Performance Battery (SPPB) and physical strength with a dynamometer. Sarcopenia was assessed based upon EWGSOP criteria. We used linear regression to model associations between body composition, sarcopenia and physical performance scores. 104 women with HIV and 212 women without HIV were enrolled (mean age 52.4±8.2 vs. 56.4±8.8 years, p≤0.001). Among women with HIV, mean years since diagnosis was 11.8±6 and all were on ART. Mean SPPB score was 9.9 vs 10.8 (p<0.001) between both groups. Sarcopenia spectrum was found in 25.9% and 23.1%, respectively. In the multivariable regression analysis, trunk FM and older age were negatively correlated with physical performance among women with HIV. Severe sarcopenia was found among a greater proportion of those with HIV (3.8% vs. 0.9%, p = 0.84), however this finding was not statistically significant. Women with HIV had significantly lower SPPB scores compared to women without HIV, and trunk FM and upper limb LM were independent predictors for the SPPB and Grip Strength tests, respectively. Larger, prospective studies are needed in Latin America & the Caribbean to identify individuals at high risk for sarcopenia and declines in physical function, and to inform prevention guidelines.
    Language English
    Publishing date 2023-08-18
    Publishing country United States
    Document type Journal Article
    ISSN 2767-3375
    ISSN (online) 2767-3375
    DOI 10.1371/journal.pgph.0000814
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  10. Article ; Online: HIV and COVID-19 in Latin America and the Caribbean.

    Garcia, Patricia J / Cabrera, Diego M / Cárcamo, Paloma M / Diaz, Monica M

    Current HIV/AIDS reports

    2022  Volume 19, Issue 1, Page(s) 37–45

    Abstract: Purpose of review: Latin America and the Caribbean (LAC) has been hit hard by COVID-19 due to political instability, flawed health systems, and structural inequalities. The repercussion of the pandemic on vulnerable populations, like people living with ... ...

    Abstract Purpose of review: Latin America and the Caribbean (LAC) has been hit hard by COVID-19 due to political instability, flawed health systems, and structural inequalities. The repercussion of the pandemic on vulnerable populations, like people living with HIV (PLWH), is complex. This review aims to explore the interactions between the HIV and COVID-19 pandemics in this region.
    Recent findings: Data regarding the interactions of HIV and COVID-19 in LAC is scarce. Only case reports or small case series have been published regarding the clinical course of COVID-19 in PLWH and regarding the clinical course of COVID-19 in PLWH, which appears to be similar to the general population. The pandemic has disrupted prevention and treatment of PLWH. However, there have been country efforts to counteract those effects. There are some lessons from the HIV response which have been effectively applied in the region to address COVID-19. COVID-19 has had an unprecedented impact on the cascade-of-care among PLWH in LAC. There is a need for longitudinal studies that assess clinic implication of these pandemic interactions in LAC.
    MeSH term(s) COVID-19/epidemiology ; Caribbean Region/epidemiology ; HIV Infections/prevention & control ; Humans ; Latin America/epidemiology ; SARS-CoV-2
    Language English
    Publishing date 2022-01-29
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2151206-1
    ISSN 1548-3576 ; 1548-3568
    ISSN (online) 1548-3576
    ISSN 1548-3568
    DOI 10.1007/s11904-021-00589-4
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