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Article ; Online: Strengthening self-regulation and reducing poverty to prevent adolescent depression and anxiety: Rationale, approach and methods of the ALIVE interdisciplinary research collaboration in Colombia, Nepal and South Africa.

Lund, Crick / Jordans, Mark J D / Garman, Emily / Araya, Ricardo / Avendano, Mauricio / Bauer, Annette / Bahure, Vikram / Dua, Tarun / Eleftheriou, Georgia / Evans-Lacko, Sara / García Rodríguez, Juan Felipe / Gautam, Kamal / Gevonden, Martin / Hessel, Philipp / Kohrt, Brandon A / Krabbendam, Lydia / Luitel, Nagendra P / Roy, Sanchari / Seifert Bonifaz, Manuel /
Singh, Rakesh / Sinichi, Mohammadamin / Sorsdahl, Katherine / Thornicroft, Graham / Tol, Wietse A / Trujillo, Daniela / van der Merwe, Nicci / Wahid, Syed Shabab / Yarrow, Paula

Epidemiology and psychiatric sciences

2023  Volume 32, Page(s) e69

Abstract: Aims: Depression and anxiety are the leading contributors to the global burden of disease among young people, accounting for over a third (34.8%) of years lived with disability. Yet there is limited evidence for interventions that prevent adolescent ... ...

Abstract Aims: Depression and anxiety are the leading contributors to the global burden of disease among young people, accounting for over a third (34.8%) of years lived with disability. Yet there is limited evidence for interventions that prevent adolescent depression and anxiety in low- and middle-income countries (LMICs), where 90% of adolescents live. This article introduces the 'Improving Adolescent mentaL health by reducing the Impact of poVErty (ALIVE)' study, its conceptual framework, objectives, methods and expected outcomes. The aim of the ALIVE study is to develop and pilot-test an intervention that combines poverty reduction with strengthening self-regulation to prevent depression and anxiety among adolescents living in urban poverty in Colombia, Nepal and South Africa.
Methods: This aim will be achieved by addressing four objectives: (1) develop a conceptual framework that identifies the causal mechanisms linking poverty, self-regulation and depression and anxiety; (2) develop a multi-component selective prevention intervention targeting self-regulation and poverty among adolescents at high risk of developing depression or anxiety; (3) adapt and validate instruments to measure incidence of depression and anxiety, mediators and implementation parameters of the prevention intervention; and (4) undertake a four-arm pilot cluster randomised controlled trial to assess the feasibility, acceptability and cost of the selective prevention intervention in the three study sites.
Results: The contributions of this study include the active engagement and participation of adolescents in the research process; a focus on the causal mechanisms of the intervention; building an evidence base for prevention interventions in LMICs; and the use of an interdisciplinary approach.
Conclusions: By developing and evaluating an intervention that addresses multidimensional poverty and self-regulation, ALIVE can make contributions to evidence on the integration of mental health into broader development policy and practice.
MeSH term(s) Adolescent ; Humans ; Anxiety/prevention & control ; Anxiety/psychology ; Colombia/epidemiology ; Depression/psychology ; Interdisciplinary Research ; Nepal ; Poverty ; Self-Control ; South Africa/epidemiology
Language English
Publishing date 2023-12-13
Publishing country England
Document type Journal Article
ZDB-ID 2607964-1
ISSN 2045-7979 ; 2045-7960
ISSN (online) 2045-7979
ISSN 2045-7960
DOI 10.1017/S2045796023000811
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